Involvement of high mobility group box 1 and the therapeutic effect of recombinant thrombomodulin in a mouse model of severe acute respiratory distress syndrome

Clinical and Experimental Immunology

Volumn 173, Issue 2, 2013, Pages 276-287

  Kudo, D ^a   Toyama, M ^a   Aoyagi, T ^a   Akahori, Y ^a   Yamamoto, H ^a   Ishii, K ^a   Kanno, E ^a   Maruyama, R ^a   Kaku, M ^a   Kushimoto, S ^a   Kawakami, K ^a  

^a TOHOKU UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

ARDS; HMGB1; IL 10; regulatory T cells; TGF ; Thrombomodulin

Indexed keywords

GAMMA INTERFERON; HIGH MOBILITY GROUP B1 PROTEIN; INTERLEUKIN 10; RECOMBINANT THROMBOMODULIN; TRANSFORMING GROWTH FACTOR BETA;

ADULT RESPIRATORY DISTRESS SYNDROME; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; DISEASE SEVERITY; LUNG ALVEOLUS EPITHELIUM; MACROPHAGE; MOUSE; NEUTROPHIL CHEMOTAXIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; REGULATORY T LYMPHOCYTE; SURVIVAL TIME;

ARDS; HMGB1; IL-10; REGULATORY T CELLS; TGF-Β; THROMBOMODULIN;

ANIMALS; ANTIGENS, CD4; DISEASE MODELS, ANIMAL; FORKHEAD TRANSCRIPTION FACTORS; GENE EXPRESSION REGULATION; HMGB1 PROTEIN; HUMANS; INTERLEUKIN-2 RECEPTOR ALPHA SUBUNIT; LUNG; MICE; MICE, INBRED C57BL; RECOMBINANT PROTEINS; RESPIRATORY DISTRESS SYNDROME, ADULT; T-LYMPHOCYTES, REGULATORY; THROMBOMODULIN;

EID: 84880027477     PISSN: 00099104     EISSN: 13652249     Source Type: Journal    
DOI: 10.1111/cei.12106     Document Type: Article

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