Interleukin-1 receptor associated kinases-1/4 inhibition protects against acute hypoxia/ischemia-induced neuronal injury in vivo and in vitro

Neuroscience

Volumn 196, Issue , 2011, Pages 25-34

  Yang, Y F ^a   Chen, Z ^a   Hu, S L ^a   Hu, J ^a   Li, B ^a   Li, J T ^a   Wei, L J ^a   Qian, Z M ^a   Lin, J K ^a   Feng, H ^a   Zhu, G ^a  

^a THIRD MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

Inflammation; IRAK 1; IRAK 1 4 inhibitor; IRAK 4; Ischemic stroke; Neuron

Indexed keywords

CASPASE 3; COBALT CHLORIDE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1 RECEPTOR ASSOCIATED KINASE 1; INTERLEUKIN 1 RECEPTOR ASSOCIATED KINASE 4; INTERLEUKIN 6; STRESS ACTIVATED PROTEIN KINASE; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 4; TRANSCRIPTION FACTOR RELA; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN CORTEX; BRAIN HYPOXIA; BRAIN INFARCTION; BRAIN INFARCTION SIZE; BRAIN ISCHEMIA; CELL VIABILITY; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOTOXICITY; ENZYME INHIBITION; FUNCTIONAL DISEASE; IMMUNOFLUORESCENCE; IMMUNOREACTIVITY; IN VITRO STUDY; IN VIVO STUDY; MALE; MIDDLE CEREBRAL ARTERY OCCLUSION; MORTALITY; NERVE CELL LESION; NEUROBLASTOMA; NEUROLOGIC DISEASE; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; RAT; SIGNAL TRANSDUCTION;

ANIMALS; APOPTOSIS; BRAIN INFARCTION; CASPASE 3; CELLS, CULTURED; CEREBRAL CORTEX; COBALT; DISEASE MODELS, ANIMAL; ENZYME INHIBITORS; HUMANS; HYPOXIA-ISCHEMIA, BRAIN; INFARCTION, MIDDLE CEREBRAL ARTERY; INTERLEUKIN-1 RECEPTOR-ASSOCIATED KINASES; INTERLEUKIN-6; JNK MITOGEN-ACTIVATED PROTEIN KINASES; MALE; NEURONS; NEUROPROTECTIVE AGENTS; NF-KAPPA B; RATS; RATS, SPRAGUE-DAWLEY; SIGNAL TRANSDUCTION; TUMOR NECROSIS FACTOR-ALPHA;

EID: 80054042211     PISSN: 03064522     EISSN: 18737544     Source Type: Journal    
DOI: 10.1016/j.neuroscience.2011.08.059     Document Type: Article

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