Development of an osmotically-driven pellet coated with acrylic copolymers (Eudragit® RS 30 D) for the sustained release of oxymatrine, a freely water soluble drug used to treat stress ulcers (I): In vitro and in vivo evaluation in rabbits

Drug Development and Industrial Pharmacy

Volumn 39, Issue 8, 2013, Pages 1230-1237

  Piao, Hongyu ^a   Liu, Shihong ^a   Piao, Hongze ^a   Li, Xuefeng ^a   Cui, Fude ^a  

^a SHENYANG PHARMACEUTICAL UNIVERSITY   (China)

Author keywords

Matrine; Osmotically driven; Oxymatrine; Pellets; Sustained release

Indexed keywords

EUDRAGIT RS; MATRINE; OXYMATRINE; SODIUM CHLORIDE; TIANQINGFUXIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG BIOAVAILABILITY; DRUG COATING; DRUG PELLET; IN VITRO STUDY; IN VIVO STUDY; MALE; NONHUMAN; RABBIT; SPHERONIZATION; STRESS ULCER; SUSTAINED RELEASE FORMULATION;

ACRYLIC RESINS; ALKALOIDS; ANIMALS; DELAYED-ACTION PREPARATIONS; MALE; OSMOTIC PRESSURE; QUINOLIZINES; RABBITS; SODIUM CHLORIDE; SOLUBILITY; STOMACH ULCER; STRESS, PSYCHOLOGICAL;

EID: 84879955656     PISSN: 03639045     EISSN: 15205762     Source Type: Journal    
DOI: 10.3109/03639045.2012.707206     Document Type: Article

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