Development of a novel osmotically driven drug delivery system for weakly basic drugs

European Journal of Pharmaceutics and Biopharmaceutics

Volumn 69, Issue 2, 2008, Pages 667-674

  Guthmann, C ^a,b   Lipp, R ^c   Wagner, T ^a   Kranz, H ^a  

^a BAYER PHARMA AG   (Germany)

^b FREIE UNIVERSITÄT BERLIN   (Germany)

^c ELI LILLY AND COMPANY   (United States)

Author keywords

Enteric coating; Extended release; Multiparticulates; Osmotic active; pH independent

Indexed keywords

3 [5 CHLORO 2 [2 [4 (4 FLUOROBENZYL) 2 METHYLPIPERAZIN 1 YL]-2-OXOETHOXY]PHENYL]URONIUM HYDROGEN SULFATE; ACRYLIC ACID ETHYL ESTER; CHLORIDE; COPOLYMER; DRUG; METHACRYLIC ACID; POLYVINYL ACETATE; POTASSIUM CHLORIDE; POVIDONE; SODIUM CHLORIDE; SUCROSE;

ANALYTIC METHOD; ARTICLE; DRUG DELIVERY SYSTEM; DRUG FORMULATION; DRUG RELEASE; DRUG SYNTHESIS; OSMOSIS; OSMOTIC PRESSURE; PH;

CHEMISTRY, PHARMACEUTICAL; CHEMISTRY, PHYSICAL; DRUG DELIVERY SYSTEMS; HALF-LIFE; HYDROGEN-ION CONCENTRATION; METHACRYLATES; MICROSCOPY, ELECTRON, SCANNING; OSMOSIS; PHARMACEUTIC AIDS; PHARMACEUTICAL PREPARATIONS; POLYVINYLS; POTASSIUM CHLORIDE; POVIDONE; SODIUM CHLORIDE; SOLUBILITY; SUCROSE; TABLETS, ENTERIC-COATED;

EID: 43249113881     PISSN: 09396411     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejpb.2007.12.017     Document Type: Article

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