메뉴 건너뛰기




Volumn 8, Issue 2, 2013, Pages 557-564

The effect of MAPK inhibitors and ROS modulators on cell growth and death of H2O2-treated HeLa cells

Author keywords

Cell death; HeLa cell; Hydrogen peroxide; Mitogen activated protein kinase; Reactive oxygen species

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; ACETYLCYSTEINE; ANTHRA[1,9 CD]PYRAZOL 6(2H) ONE; BUTHIONINE SULFOXIMINE; GALLIC ACID PROPYL ESTER; HYDROGEN PEROXIDE; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; REACTIVE OXYGEN METABOLITE;

EID: 84879955209     PISSN: 17912997     EISSN: 17913004     Source Type: Journal    
DOI: 10.3892/mmr.2013.1551     Document Type: Article
Times cited : (30)

References (35)
  • 1
    • 0036667555 scopus 로고    scopus 로고
    • Superoxide dismutase multigene family: A comparison of the CuZn-SOD (SOD1), Mn-SOD (SOD2), and EC-SOD (SOD3) gene structures, evolution, and expression
    • Zelko IN, Mariani TJ and Folz RJ: Superoxide dismutase multigene family: a comparison of the CuZn-SOD (SOD1), Mn-SOD (SOD2), and EC-SOD (SOD3) gene structures, evolution, and expression. Free Radic Biol Med 33: 337-349, 2002.
    • (2002) Free Radic Biol Med , vol.33 , pp. 337-349
    • Zelko, I.N.1    Mariani, T.J.2    Folz, R.J.3
  • 2
    • 0036548475 scopus 로고    scopus 로고
    • Reactive oxygen species: Roles in blood pressure and kidney function
    • Wilcox CS: Reactive oxygen species: roles in blood pressure and kidney function. Curr Hypertens Rep 4: 160-166, 2002.
    • (2002) Curr Hypertens Rep , vol.4 , pp. 160-166
    • Wilcox, C.S.1
  • 3
    • 34447631168 scopus 로고    scopus 로고
    • Oxyl radicals, redox-sensitive signalling cascades and antioxidants
    • Genestra M: Oxyl radicals, redox-sensitive signalling cascades and antioxidants. Cell Signal 19: 1807-1819, 2007.
    • (2007) Cell Signal , vol.19 , pp. 1807-1819
    • Genestra, M.1
  • 4
    • 0027233448 scopus 로고
    • Signal transduction via the MAP kinases: Proceed at your own RSK
    • Blenis J: Signal transduction via the MAP kinases: proceed at your own RSK. Proc Natl Acad Sci USA 90: 5889-5892, 1993.
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 5889-5892
    • Blenis, J.1
  • 5
    • 0032547814 scopus 로고    scopus 로고
    • P38 Kinase is a negative regulator of angiotensin II signal transduction in vascular smooth muscle cells: Effects on Na+/H+ exchange and ERK1/2
    • Kusuhara M, Takahashi E, Peterson TE, Abe J, Ishida M, Han J, Ulevitch R and Berk BC: p38 Kinase is a negative regulator of angiotensin II signal transduction in vascular smooth muscle cells: effects on Na+/H+ exchange and ERK1/2. Circ Res 83: 824-831, 1998.
    • (1998) Circ Res , vol.83 , pp. 824-831
    • Kusuhara, M.1    Takahashi, E.2    Peterson, T.E.3    Abe, J.4    Ishida, M.5    Han, J.6    Ulevitch, R.7    Berk, B.C.8
  • 6
    • 45849153496 scopus 로고    scopus 로고
    • The apoptotic effect of nanosilver is mediated by a ROS- and JNK-dependent mechanism involving the mitochondrial pathway in NIH3T3 cells
    • Hsin YH, Chen CF, Huang S, Shih TS, Lai PS and Chueh PJ: The apoptotic effect of nanosilver is mediated by a ROS- and JNK-dependent mechanism involving the mitochondrial pathway in NIH3T3 cells. Toxicol Lett 179: 130-139, 2008.
    • (2008) Toxicol Lett , vol.179 , pp. 130-139
    • Hsin, Y.H.1    Chen, C.F.2    Huang, S.3    Shih, T.S.4    Lai, P.S.5    Chueh, P.J.6
  • 7
    • 49149088537 scopus 로고    scopus 로고
    • Induction of apoptosis by shikonin through a ROS/JNK-mediated process in Bcr/Abl-positive chronic myelogenous leukemia (CML) cells
    • Mao X, Yu CR, Li WH and Li WX: Induction of apoptosis by shikonin through a ROS/JNK-mediated process in Bcr/Abl-positive chronic myelogenous leukemia (CML) cells. Cell Res 18: 879-888, 2008.
    • (2008) Cell Res , vol.18 , pp. 879-888
    • Mao, X.1    Yu, C.R.2    Li, W.H.3    Li, W.X.4
  • 8
    • 70350783602 scopus 로고    scopus 로고
    • JNK and p38 inhibitors increase and decrease apoptosis, respectively, in pyrogallol-treated calf pulmonary arterial endothelial cells
    • Han YH, Moon HJ, You BR, Kim SZ, Kim SH and Park WH: JNK and p38 inhibitors increase and decrease apoptosis, respectively, in pyrogallol-treated calf pulmonary arterial endothelial cells. Int J Mol Med 24: 717-722, 2009.
    • (2009) Int J Mol Med , vol.24 , pp. 717-722
    • Han, Y.H.1    Moon, H.J.2    You, B.R.3    Kim, S.Z.4    Kim, S.H.5    Park, W.H.6
  • 9
    • 0942287674 scopus 로고    scopus 로고
    • Enhanced survival effect of pyruvate correlates MAPK and NF-kappaB activation in hydrogen peroxide-treated human endothelial cells
    • Lee YJ, Kang IJ, Bünger R and Kang YH: Enhanced survival effect of pyruvate correlates MAPK and NF-kappaB activation in hydrogen peroxide-treated human endothelial cells. J Appl Physiol 96: 792-801, 2004.
    • (2004) J Appl Physiol , vol.96 , pp. 792-801
    • Lee, Y.J.1    Kang, I.J.2    Bünger, R.3    Kang, Y.H.4
  • 10
    • 0030049439 scopus 로고    scopus 로고
    • Activation of mitogen-activated protein kinase by H2O2. Role in cell survival following oxidant injury
    • Guyton KZ, Liu Y, Gorospe M, Xu Q and Holbrook NJ: Activation of mitogen-activated protein kinase by H2O2. Role in cell survival following oxidant injury. J Biol Chem 271: 4138-4142, 1996.
    • (1996) J Biol Chem , vol.271 , pp. 4138-4142
    • Guyton, K.Z.1    Liu, Y.2    Gorospe, M.3    Xu, Q.4    Holbrook, N.J.5
  • 11
    • 33750412872 scopus 로고    scopus 로고
    • Surviving cell death through epidermal growth factor (EGF) signal transduction pathways: Implications for cancer therapy
    • Henson ES and Gibson SB: Surviving cell death through epidermal growth factor (EGF) signal transduction pathways: implications for cancer therapy. Cell Signal 18: 2089-2097, 2006.
    • (2006) Cell Signal , vol.18 , pp. 2089-2097
    • Henson, E.S.1    Gibson, S.B.2
  • 12
    • 15044362438 scopus 로고    scopus 로고
    • Intracellular messenger function of hydrogen peroxide and its regulation by peroxiredoxins
    • Rhee SG, Kang SW, Jeong W, Chang TS, Yang KS and Woo HA: Intracellular messenger function of hydrogen peroxide and its regulation by peroxiredoxins. Curr Opin Cell Biol 17: 183-189, 2005.
    • (2005) Curr Opin Cell Biol , vol.17 , pp. 183-189
    • Rhee, S.G.1    Kang, S.W.2    Jeong, W.3    Chang, T.S.4    Yang, K.S.5    Woo, H.A.6
  • 13
    • 1842510009 scopus 로고    scopus 로고
    • The phagocyte NADPH oxidase depends on cholesterol-enriched membrane microdomains for assembly
    • Vilhardt F and van Deurs B: The phagocyte NADPH oxidase depends on cholesterol-enriched membrane microdomains for assembly. EMBO J 23: 739-748, 2004.
    • (2004) EMBO J , vol.23 , pp. 739-748
    • Vilhardt, F.1    Van Deurs, B.2
  • 14
    • 68349109741 scopus 로고    scopus 로고
    • The effects of N-acetyl cysteine, buthionine sulfoximine, diethyldithiocarbamate or 3-amino-1,2,4-triazole on antimycin A-treated Calu-6 lung cells in relation to cell growth, reactive oxygen species and glutathione
    • Han YH and Park WH: The effects of N-acetyl cysteine, buthionine sulfoximine, diethyldithiocarbamate or 3-amino-1,2,4-triazole on antimycin A-treated Calu-6 lung cells in relation to cell growth, reactive oxygen species and glutathione. Oncol Rep 22: 385-391, 2009.
    • (2009) Oncol Rep , vol.22 , pp. 385-391
    • Han, Y.H.1    Park, W.H.2
  • 15
    • 71749103032 scopus 로고    scopus 로고
    • Effects of carbonyl cyanide p-(trifluoromethoxy) phenylhydrazone on the growth inhibition in human pulmonary adenocarcinoma Calu-6 cells
    • Han YH, Moon HJ, You BR, Kim SZ, Kim SH and Park WH: Effects of carbonyl cyanide p-(trifluoromethoxy) phenylhydrazone on the growth inhibition in human pulmonary adenocarcinoma Calu-6 cells. Toxicology 265: 101-107, 2009.
    • (2009) Toxicology , vol.265 , pp. 101-107
    • Han, Y.H.1    Moon, H.J.2    You, B.R.3    Kim, S.Z.4    Kim, S.H.5    Park, W.H.6
  • 16
    • 49349086137 scopus 로고    scopus 로고
    • Pyrogallol inhibits the growth of human lung cancer Calu-6 cells via arresting the cell cycle arrest
    • Han YH, Kim SZ, Kim SH and Park WH: Pyrogallol inhibits the growth of human lung cancer Calu-6 cells via arresting the cell cycle arrest. Toxicol In Vitro 22: 1605-1609, 2008.
    • (2008) Toxicol in Vitro , vol.22 , pp. 1605-1609
    • Han, Y.H.1    Kim, S.Z.2    Kim, S.H.3    Park, W.H.4
  • 17
    • 68249153842 scopus 로고    scopus 로고
    • The effect of MG132, a proteasome inhibitor on HeLa cells in relation to cell growth, reactive oxygen species and GSH
    • Han YH, Moon HJ, You BR and Park WH: The effect of MG132, a proteasome inhibitor on HeLa cells in relation to cell growth, reactive oxygen species and GSH. Oncol Rep 22: 215-221, 2009.
    • (2009) Oncol Rep , vol.22 , pp. 215-221
    • Han, Y.H.1    Moon, H.J.2    You, B.R.3    Park, W.H.4
  • 18
    • 58149131828 scopus 로고    scopus 로고
    • Carbonyl cyanide p-(trifluoromethoxy) phenylhydrazone (FCCP) as an O2•- generator induces apoptosis via the depletion of intracellular GSH contents in Calu-6 cells
    • Han YH, Kim SH, Kim SZ and Park WH: Carbonyl cyanide p-(trifluoromethoxy) phenylhydrazone (FCCP) as an O2•- generator induces apoptosis via the depletion of intracellular GSH contents in Calu-6 cells. Lung Cancer 63: 201-209, 2009.
    • (2009) Lung Cancer , vol.63 , pp. 201-209
    • Han, Y.H.1    Kim, S.H.2    Kim, S.Z.3    Park, W.H.4
  • 19
    • 69549116458 scopus 로고    scopus 로고
    • Propyl gallate inhibits the growth of HeLa cells via regulating intracellular GSH level
    • Han YH and Park WH: Propyl gallate inhibits the growth of HeLa cells via regulating intracellular GSH level. Food Chem Toxicol 47: 2531-2538, 2009.
    • (2009) Food Chem Toxicol , vol.47 , pp. 2531-2538
    • Han, Y.H.1    Park, W.H.2
  • 20
    • 45149125713 scopus 로고    scopus 로고
    • Intracellular GSH level is a factor in As4.1 juxtaglomerular cell death by arsenic trioxide
    • Han YH, Kim SZ, Kim SH and Park WH: Intracellular GSH level is a factor in As4.1 juxtaglomerular cell death by arsenic trioxide. J Cell Biochem 104: 995-1009, 2008.
    • (2008) J Cell Biochem , vol.104 , pp. 995-1009
    • Han, Y.H.1    Kim, S.Z.2    Kim, S.H.3    Park, W.H.4
  • 22
    • 36048939725 scopus 로고    scopus 로고
    • Hydrogen peroxide induces apoptosis in HeLa cells through mitochondrial pathway
    • Singh M, Sharma H and Singh N: Hydrogen peroxide induces apoptosis in HeLa cells through mitochondrial pathway. Mitochondrion 7: 367-373, 2007.
    • (2007) Mitochondrion , vol.7 , pp. 367-373
    • Singh, M.1    Sharma, H.2    Singh, N.3
  • 23
    • 50849105753 scopus 로고    scopus 로고
    • Mammalian 105 kDa heat shock family proteins suppress hydrogen peroxide-induced apoptosis through a p38 MAPK-dependent mitochondrial pathway in HeLa cells
    • Yamagishi N, Saito Y and Hatayama T: Mammalian 105 kDa heat shock family proteins suppress hydrogen peroxide-induced apoptosis through a p38 MAPK-dependent mitochondrial pathway in HeLa cells. FEBS J 275: 4558-4570, 2008.
    • (2008) FEBS J , vol.275 , pp. 4558-4570
    • Yamagishi, N.1    Saito, Y.2    Hatayama, T.3
  • 26
    • 1242317093 scopus 로고    scopus 로고
    • Metal-mediated oxidative damage to cellular and isolated DNA by gallic acid, a metabolite of antioxidant propyl gallate
    • Kobayashi H, Oikawa S, Hirakawa K and Kawanishi S: Metal-mediated oxidative damage to cellular and isolated DNA by gallic acid, a metabolite of antioxidant propyl gallate. Mutat Res 558: 111-120, 2004.
    • (2004) Mutat Res , vol.558 , pp. 111-120
    • Kobayashi, H.1    Oikawa, S.2    Hirakawa, K.3    Kawanishi, S.4
  • 27
    • 28844448258 scopus 로고    scopus 로고
    • Evaluation for safety of antioxidant chemopreventive agents
    • Kawanishi S, Oikawa S and Murata M: Evaluation for safety of antioxidant chemopreventive agents. Antioxid Redox Signal 7: 1728-1739, 2005.
    • (2005) Antioxid Redox Signal , vol.7 , pp. 1728-1739
    • Kawanishi, S.1    Oikawa, S.2    Murata, M.3
  • 28
    • 77952771818 scopus 로고    scopus 로고
    • Propyl gallate inhibits the growth of endothelial cells, especially calf pulmonary arterial endothelial cells via caspase-independent apoptosis
    • Han YH, Moon HJ, You BR, Yang YM, Kim SZ, Kim SH and Park WH: Propyl gallate inhibits the growth of endothelial cells, especially calf pulmonary arterial endothelial cells via caspase-independent apoptosis. Int J Mol Med 25: 937-944, 2010.
    • (2010) Int J Mol Med , vol.25 , pp. 937-944
    • Han, Y.H.1    Moon, H.J.2    You, B.R.3    Yang, Y.M.4    Kim, S.Z.5    Kim, S.H.6    Park, W.H.7
  • 29
    • 0032054199 scopus 로고    scopus 로고
    • DNA strand break induction and enhanced cytotoxicity of propyl gallate in the presence of copper(II)
    • Jacobi H, Eicke B and Witte I: DNA strand break induction and enhanced cytotoxicity of propyl gallate in the presence of copper(II). Free Radic Biol Med 24: 972-978, 1998.
    • (1998) Free Radic Biol Med , vol.24 , pp. 972-978
    • Jacobi, H.1    Eicke, B.2    Witte, I.3
  • 30
    • 51049093020 scopus 로고    scopus 로고
    • Enhancement of arsenic trioxide-induced apoptosis in HeLa cells by diethyldithiocarbamate or buthionine sulfoximine
    • Han YH, Kim SZ, Kim SH and Park WH: Enhancement of arsenic trioxide-induced apoptosis in HeLa cells by diethyldithiocarbamate or buthionine sulfoximine. Int J Oncol 33: 205-213, 2008.
    • (2008) Int J Oncol , vol.33 , pp. 205-213
    • Han, Y.H.1    Kim, S.Z.2    Kim, S.H.3    Park, W.H.4
  • 31
    • 53449092255 scopus 로고    scopus 로고
    • Suppression of arsenic trioxide-induced apoptosis in HeLa cells by N-acetylcysteine
    • Han YH, Kim SZ, Kim SH and Park WH: Suppression of arsenic trioxide-induced apoptosis in HeLa cells by N-acetylcysteine. Mol Cells 26: 18-25, 2008.
    • (2008) Mol Cells , vol.26 , pp. 18-25
    • Han, Y.H.1    Kim, S.Z.2    Kim, S.H.3    Park, W.H.4
  • 33
    • 53749094063 scopus 로고    scopus 로고
    • Induction of apoptosis in arsenic trioxide-treated lung cancer A549 cells by buthionine sulfoximine
    • Han YH, Kim SZ, Kim SH and Park WH: Induction of apoptosis in arsenic trioxide-treated lung cancer A549 cells by buthionine sulfoximine. Mol Cells 26: 158-164, 2008.
    • (2008) Mol Cells , vol.26 , pp. 158-164
    • Han, Y.H.1    Kim, S.Z.2    Kim, S.H.3    Park, W.H.4
  • 35
    • 42649083649 scopus 로고    scopus 로고
    • Quercetin decreases intracellular GSH content and potentiates the apoptotic action of the antileukemic drug arsenic trioxide in human leukemia cell lines
    • Ramos AM and Aller P: Quercetin decreases intracellular GSH content and potentiates the apoptotic action of the antileukemic drug arsenic trioxide in human leukemia cell lines. Biochem Pharmacol 75: 1912-1923, 2008.
    • (2008) Biochem Pharmacol , vol.75 , pp. 1912-1923
    • Ramos, A.M.1    Aller, P.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.