Evaluation of anti-inflammatory and antinoceceptive activity of xanthones from Swertia Corymbosa (Griseb.) Wight ex C.B. Clarke

International Journal of Pharmacy and Pharmaceutical Sciences

Volumn 5, Issue 3, 2013, Pages 523-529

  Mahendran, G ^a   Manoj, M ^a   Rajendra Prasad, K J ^a   Narmatha Bai, V ^a  

^a BHARATHIAR UNIVERSITY   (India)

Author keywords

Anti inflammatory; Carrageenan induced paw edema; Swertia corymbosa; Xanthone dixylopyranoside

Indexed keywords

1, 2, DIHYDROXY 6 METHOXYXANTHONE 8 O BETA D XYLOPYRANOSYL; 1, 8 DIHYDROXY 2, 6 DIMETHOXYXANTHONE; 8 HYDROXY 1, 2, 4, 6 TETRAMETHOXYXANTHONE; DECUSSATIN; GENTIACAULEIN; INDOMETACIN; PENTAZOCINE; SWERTIANIN; UNCLASSIFIED DRUG; XANTHONE DERIVATIVE;

ACUTE TOXICITY; ANALGESIC ACTIVITY; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIINFLAMMATORY ACTIVITY; ANTINOCICEPTION; ARTICLE; CONTROLLED STUDY; HOT PLATE TEST; MALE; MOUSE; NONHUMAN; RAT; SPECTROSCOPY;

EID: 84879902053     PISSN: None     EISSN: 09751491     Source Type: Journal    
DOI: None     Document Type: Article

References (45)

1. Kumar V, Abbas AK, Fausto N. Pathologic basic of disease. 7th ed. Elsevier Saundar. 2004.
2. Simmones DL. What makes a good Anti-inflammatory drug target? Drug Discov Today. 2006; 11:210-9.
3. Parenteau NL, Hardin-Young J. The biological mechanisms behind injury and inflammation: how they can affect treatment strategy, product performance and healing. Wounds 2007; 19:87-96.
4. Vane JR, Bolting RM. New insights into the mode of action of anti-inflammatory drugs. Inflamm. Res 1995; 44(1):1-10.
5. Stevens RJ, Douglas KMJ, Saratzis AN, Kitas GD. Inflammation and atherosclerosis in rheumatoid arthritis. Exp. Rev. Mol. Med 2005; 7:1-24.
6. Klareskog L, Padyukov L, Ronnelid J, Alfredsson L. Genes, envitronment immunity in the development of rheumatoid arthritis. Curr. Opin. Immunol 2006; 18:650-5.
7. Simka M. Blood brain barrier compromise with endothelial inflammation may lead to autoimmune loss of myelin during multiple sclerosis. Curr. Neurovasc. Res 2009; 6:132-9.
8. Kong DX, Li XY, Zhang HY. Where is the hope for drug discovery? Let history tell the future. Drug Discov Today 2008; 14:115-119.
9. Ahmed VU, Rahman IU, Khan MA, Arfan M, Siddique MT. A xanthone dixylopyranosis from Swertia thomsonii. Z Naturforsch 2002; 57:122-126.
10. Pant N, Jain DC, Bhakuni RS. Phytochemicals from genus Swertia and their biological activities. Indian J Chem 2000; 39:565-586.
11. Singh PP, Ambika, Chauhan, S. Activity-guided isolation of antioxidant xanthones from Swertia chirayita (Roxb.) H. Karsten (Gentianaceae). Nat Prod Res 2012; 26:1682-1686.
12. Jung HA, Su BN, Keller WJ, Mehta RG, Kinghorn AD. Antioxidant xanthones from the pericarp of Garcinia mangostana (Mangosteen). J Agri Food Chem 2006; 54:2077-2082.
13. Lee BW, Lee JH, Lee ST, Lee HS, Lee WS, Jeong TS, Park KH. Antioxidant and cytotoxic activities of xanthones from Cudrania tricuspidata. Bioorg Med Chem Let 2005; 15:5548.
14. Lin CN, Chung MI, Liou SJ, Lee TH, Wang JP. Synthesis and anti-inflammatory effects of xanthone derivatives. J Pharm Pharmacol 1996; 48:532-538.
15. Valenti P, Bisi A, Rampa A, Belluti F, Gobbi S, Zampiron A, Carrara M. Synthesis and biological activity of some rigid analogues of flavone-8-acetic acid. Bioorg Med Chem 2000; 8:239-246.
16. Pedro M, Cerqueira F, Sousa ME, Nascimento MSJ, Pinto M. Xanthones as inhibitors of growth of human cancer cell lines and their effects on the proliferation of human lymphocytes in vitro. Bioorg Med Chem 2002; 10:3725-3730.
17. Seo EJ, Curtis-Long MJ, Lee BW, Kim, HY, Ryu YB, Jeong TS, Lee WS, Park KH. Xanthones from Cudrania tricuspidata displaying potent α-glucosidase inhibition. Bioorg Med Chem Let 2007; 17:6421-6424.
18. Li GL, He JY, Zhang A, Wan Y, Wang B, Chen WH. Toward potent α-glucosidase inhibitors based on xanthones: a closer look into the structure-activity correlations. Eur J Med Chem 2011; 46:4050-4055.
19. Brahmachari G, Monda S, Gangopadhyay A, Gorai D, Mukhopadhyay B, Saha S, Brahmachari AK. Swertia (Gentianaceae): Chemical and Pharmacological Aspects. Chem Biodivers 2004; 1:1627-1651.
20. Abraham Z. Ethnobotany of the Todas, the Kotas, the Irulas of the Nilgiris. In Jain SK. (Ed.), Glimpses of Indian Ethnobotany. Oxford & IBH, New Delhi. 1981. pp. 26-30.
21. Ramesh N, Vishwanathan MB, Saraswathy A, Balakrishna K, Brindha P, Perumalsamy PL, Antimicrobial and phytochemical studies of Swertia corymbosa. Fitoterapia 2002; 73:160-164.
22. Selvameena P, Arumugasamy K, Baluprakash T, Kokilavani R, Balakrishnan A. Antioxidant activity of methanolic extract of Swertia corymbosa (Griseb) Wight Ex Clarke (Gentianaceae) on alloxan induced diabetic rates. Int Res J Pharm 2010; 1:392-394.
23. Mahendran G, Narmatha Bai V. Evaluation of analgesic, anti-inflammatory and antipyretic potential of methanol extract of aerial parts of swertia corymbosa (griseb.) wight ex C.B. Clarke. Int J Pharm Pharml Sci 2013; 5:459-463.
24. Saraswathy A, Ariyanathan S, 1, 5, 8-Trihydroxy-3-methoxyxanthone from Swertia corymbosa (Griseb.) Wight ex C.B. Clarke. Int J Pharm Life Sci 2011; 2:976-977.
25. MacDonald AD, Woolfe G, Bergel F, Morrison AL, Rinderknecht H. Analgesic action of pethidine derivatives and related compounds. Br J Pharmacol 1946; 1:4-14.
26. Siegmund E, Cadmus R, Lu G. A method for evaluating both non-narcotic and non narcotic analgesics. Proc Soc Exp Biol Med 1957; 95:729-731.
27. Vasudevan M, Gunnam KK, Parle M. Antinociceptive and anti-inflammatory properties of Daucus carota seeds extract. J Health Sci 2006; 52:598-606.
28. Chintalwar GJ, Chattopadhyay S. Structural conformation of decussatin, a Swertia decussata xanthone. Nat Prod Res 2006; 20:53-56.
29. Uvarani C, Chandraprakash K, Sankaran M, Ata A, Mohan PS. Antioxidant and structure-activity relationships of five tetra oxygenated xanthones from Swertia minor (Griscb.) Knob. Nat Prod Res 2012; 26:1265-1270
30. Tian LY, Bai X, Chen XH, Fang JB, Liu SH, Chen JC. Anti-diabetic effect of methylswertianin and bellidifolin from Swertia punicea Hemsl. and its potential mechanism Phytomed 2010; 17:533-539.
31. Markham KR. Techniques of Flavonoid identification. Academic press London. 1982.
32. Mendesa SS, Bomfima RR, Jesus HCR, Alvesb PB, Blank AF, Estevama CS, Antoniollia AR, Thomazzia SM. Evaluation of the analgesic and anti-inflammatory effects of the essential oil of Lippia gracilis leaves. J Ethnopharmacol 2010; 129:391-397.
33. Firdous SM and Koneri R. In vivo and in vitro anti-inflammatory activity of leaves of Ipomoea staphylina. Int J Pharm Pharml Sci 2012; 4:339-343.
34. Amutha D, Shanthi S and Mariappan. V. Antiflammatory effect of Tarenna asiatica (L) in carrageenan induced lung inflammation. Int J Pharm Pharml Sci 2012; 4:344-347.
35. Panthong A, Kanjanapothi D, Taesotikul T, Wongcome T, Reutrakul V. Anti-inflammatory and antipyretic properties of Clerodendrum petasites. S. Moore. J Ethnopharmacol 2003; 85:151-156.
36. Chen LG, Yang LL, Wang CC. Anti-inflammatory activity of mangostins from Garcinia mangostana. Food Chem Toxicol 2007; 46:688-693.
37. Nakatani K, Yamakuni T, Kondo N, Arakawa T, Oosawa K, Shimura S, Inoue H, Ohizumi Y. γ-Mangostin inhibits inhibitor-KB kinase activity and decreases lipoplysaccharide-inducedcyclooxygenase-2 gene expression in C6 rat glioma cells. Mol Pharmacol 2004; 66:667-674.
38. Banerjee S, Sur TK, Mandal S, Das PC, Sikdar S. Assessment of the anti-inflammatory effects of Swertia chirata in acute and chronic experimental models in male albino rats. Indian J Pharmacol 2000; 32:21-24.
39. Khan H, Saeed M, Gilani AU, Khan MA, Khan I, Ashraf N. Antinociceptive activity of aerial parts of polygonatum verticillatum: attenuation of both peripheral and central pain mediators. Phytother Res 2011; 25:1024-1030.
40. Le Bars D, Gozariu M, Cadden SW. Animal models of nociception. Pharmacol Rev 2001; 53:597-652.
41. De Souza ET, Lira DP, Queiroz AC, Silva DJC, Aquino AB, Mella EAC, Lorenzo VL, Miranda GEC, Araujo-Junior JX, Chaves MCO. The antinociceptive and anti-inflammatory activities of caulerpin, a bisindole alkaloid isolated from seaweeds of the genus Caulerpa. Mar Drugs 2009; 7:689-704.
42. Ikeda A, Ueno H, Naraba H, Ohishi S. Involvement of vanilloid receptor VR1 and prostanoids in the acid induced writhing responses of mice. Life Sci 2001; 69:2911-2919
43. Bley KR, Hunter JC, Eglen RM, Smith JA. The role of IP prostanoid receptors in inflammatory pain. Trends Pharmacol Sci 1998; 19:141-147.
44. Islam CN, Bandyopadhyay SK, Banerjee MK, Das PC. Preliminary studies on the anti-inflammatory effects of Swertia chirata in albino rats. Indian J Pharmacol 1995; 27:37-39.
45. Kim HK, Park SK, Zhou JL, Taglialatela G, Chung K, Coggeshall RE, Chung JM. Reactive oxygen species (ROS) play an important role in a rat model of neuropathic pain. Pain 2004; 111:116-124.