Procalcitonin after cardiac arrest - An indicator of severity of illness, ischemia-reperfusion injury and outcome

Resuscitation

Volumn 84, Issue 6, 2013, Pages 782-787

  Annborn, Martin ^a   Dankiewicz, Josef ^a   Erlinge, David ^a   Hertel, Sabine ^b   Rundgren, Malin ^a   Smith, J Gustav ^a   Struck, Joachim ^b   Friberg, Hans ^a  

^a LUND UNIVERSITY   (Sweden)

^b THERMO FISHER SCIENTIFIC   (Germany)

Author keywords

Cardiac arrest; Hypothermia; Infection; Outcome; Post cardiac arrest syndrome; Procalcitonin

Indexed keywords

C REACTIVE PROTEIN; PROCALCITONIN;

ACCURACY; ADULT; AGED; ARTICLE; BRAIN FUNCTION; DISEASE SEVERITY; FEMALE; HEART ARREST; HORMONE BLOOD LEVEL; HUMAN; INDUCED HYPOTHERMIA; INFECTION; MAJOR CLINICAL STUDY; MALE; NEUROLOGICAL COMPLICATION; OUTCOME ASSESSMENT; POST CARDIAC ARREST SYNDROME; PREDICTIVE VALUE; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; REPERFUSION INJURY; RETURN OF SPONTANEOUS CIRCULATION; SYSTEMIC INFLAMMATORY RESPONSE SYNDROME;

AGED; BIOLOGICAL MARKERS; C-REACTIVE PROTEIN; CALCITONIN; FEMALE; HEART ARREST; HUMANS; HYPOTHERMIA, INDUCED; MALE; MIDDLE AGED; PROSPECTIVE STUDIES; PROTEIN PRECURSORS; REPERFUSION INJURY; SEVERITY OF ILLNESS INDEX; SWEDEN; TREATMENT OUTCOME;

EID: 84879888133     PISSN: 03009572     EISSN: 18731570     Source Type: Journal    
DOI: 10.1016/j.resuscitation.2013.01.004     Document Type: Article

References (37)

1. Nolan J.P., Neumar R.W., Adrie C., et al. Post-cardiac arrest syndrome: epidemiology, pathophysiology, treatment, and prognostication. A Scientific Statement from the International Liaison Committee on Resuscitation; the American Heart Association Emergency Cardiovascular Care Committee; the Council on Cardiovascular Surgery and Anesthesia; the Council on Cardiopulmonary, Perioperative, and Critical Care; the Council on Clinical Cardiology; the Council on Stroke. Resuscitation 2008, 79:350-379.
2. Adrie C., Adib-Conquy M., Laurent I., et al. Successful cardiopulmonary resuscitation after cardiac arrest as a "sepsis-like" syndrome. Circulation 2002, 106:562-568.
3. Hazinski M.F., Nolan J.P., Billi J.E., et al. Part 1: Executive summary: 2010 International Consensus on Cardiopulmonary Resuscitation and Emergency Cardiovascular Care Science With Treatment Recommendations. Circulation 2010, 122:S250-S275.
4. Zandbergen E.G., Hijdra A., Koelman J.H., et al. Prediction of poor outcome within the first 3 days of postanoxic coma. Neurology 2006, 66:62-68.
5. Cronberg T., Rundgren M., Westhall E., et al. Neuron-specific enolase correlates with other prognostic markers after cardiac arrest. Neurology 2011, 77:623-630.
6. Oksanen T., Tiainen M., Skrifvars M.B., et al. Predictive power of serum NSE and OHCA score regarding 6-month neurologic outcome after out-of-hospital ventricular fibrillation and therapeutic hypothermia. Resuscitation 2009, 80:165-170.
7. Wijdicks E.F., Hijdra A., Young G.B., Bassetti C.L., Wiebe S. Practice parameter: prediction of outcome in comatose survivors after cardiopulmonary resuscitation (an evidence-based review): report of the Quality Standards Subcommittee of the American Academy of Neurology. Neurology 2006, 67:203-210.
8. Fugate J.E., Wijdicks E.F., Mandrekar J., et al. Predictors of neurologic outcome in hypothermia after cardiac arrest. Ann Neurol 2010, 68:907-914.
9. Meisner M. Pathobiochemistry and clinical use of procalcitonin. Clin Chim Acta 2002, 323:17-29.
10. Muller B., White J.C., Nylen E.S., Snider R.H., Becker K.L., Habener J.F. Ubiquitous expression of the calcitonin-i gene in multiple tissues in response to sepsis. J Clin Endocrinol Metab 2001, 86:396-404.
11. Brunkhorst F.M., Heinz U., Forycki Z.F. Kinetics of procalcitonin in iatrogenic sepsis. Intensive Care Med 1998, 24:888-889.
12. Mongardon N., Lemiale V., Perbet S., et al. Value of procalcitonin for diagnosis of early onset pneumonia in hypothermia-treated cardiac arrest patients. Intensive Care Med 2010, 36:92-99.
13. Schuetz P., Affolter B., Hunziker S., et al. Serum procalcitonin, C-reactive protein and white blood cell levels following hypothermia after cardiac arrest: a retrospective cohort study. Eur J Clin Invest 2010, 40:376-381.
14. Fries M., Kunz D., Gressner A.M., Rossaint R., Kuhlen R. Procalcitonin serum levels after out-of-hospital cardiac arrest. Resuscitation 2003, 59:105-109.
15. Fries M., Stoppe C., Brucken D., Rossaint R., Kuhlen R. Influence of mild therapeutic hypothermia on the inflammatory response after successful resuscitation from cardiac arrest. J Crit Care 2009, 24:453-457.
16. Hayashida H., Kaneko T., Kasaoka S., et al. Comparison of the predictability of neurological outcome by serum procalcitonin and glial fibrillary acidic protein in postcardiac-arrest patients. Neurocrit Care 2010, 12:252-257.
17. Stammet P., Devaux Y., Azuaje F., et al. Assessment of procalcitonin to predict outcome in hypothermia-treated patients after cardiac arrest. Crit Care Res Pract 2011, 2011:631062.
18. Nielsen N., Wetterslev J., al-Subaie N., et al. Target Temperature Management after out-of-hospital cardiac arrest-a randomized, parallel-group, assessor-blinded clinical trial-rationale and design. Am Heart J 2012, 163:541-548.
19. Rundgren M., Karlsson T., Nielsen N., Cronberg T., Johnsson P., Friberg H. Neuron specific enolase and S-100B as predictors of outcome after cardiac arrest and induced hypothermia. Resuscitation 2009, 80:784-789.
20. Jennett B., Bond M. Assessment of outcome after severe brain damage. Lancet 1975, 1:480-484.
21. Luna C.M., Blanzaco D., Niederman M.S., et al. Resolution of ventilator-associated pneumonia: prospective evaluation of the clinical pulmonary infection score as an early clinical predictor of outcome. Crit Care Med 2003, 31:676-682.
22. Nielsen N., Sunde K., Hovdenes J., et al. Adverse events and their relation to mortality in out-of-hospital cardiac arrest patients treated with therapeutic hypothermia. Crit Care Med 2011, 39:57-64.
23. Swedish Intensive Care Registry (SIR): http://www.icuregswe.org/en/.
24. Dragancea I., Rundgren M., Englund E., Friberg H., Cronberg T. The influence of induced hypothermia and delayed prognostication on the mode of death after cardiac arrest. Resuscitation 2012, [Epub ahead of print]. 10.1016/j.resuscitation.2012.09.015.
25. Al-Nawas B., Krammer I., Shah P.M. Procalcitonin in diagnosis of severe infections. Eur J Med Res 1996, 1:331-333.
26. Adib-Conquy M., Monchi M., Goulenok C., et al. Increased plasma levels of soluble triggering receptor expressed on myeloid cells 1 and procalcitonin after cardiac surgery and cardiac arrest without infection. Shock 2007, 28:406-410.
27. Friberg H., Rundgren M., Westhall E., Nielsen N., Cronberg T. Continuous evaluation of neurological prognosis after cardiac arrest. Acta Anaesthesiol Scand 2013, 57:6-15.
28. Tang B.M., Eslick G.D., Craig J.C., McLean A.S. Accuracy of procalcitonin for sepsis diagnosis in critically ill patients: systematic review and meta-analysis. Lancet Infect Dis 2007, 7:210-217.
29. Oppert M., Reinicke A., Muller C., Barckow D., Frei U., Eckardt K.U. Elevations in procalcitonin but not C-reactive protein are associated with pneumonia after cardiopulmonary resuscitation. Resuscitation 2002, 53:167-170.
30. Tsai M.S., Chiang W.C., Lee C.C., et al. Infections in the survivors of out-of-hospital cardiac arrest in the first 7 days. Intensive Care Med 2005, 31:621-626.
31. Christ-Crain M., Jaccard-Stolz D., Bingisser R., et al. Effect of procalcitonin-guided treatment on antibiotic use and outcome in lower respiratory tract infections: cluster-randomised, single-blinded intervention trial. Lancet 2004, 363:600-607.
32. Hug A., Murle B., Dalpke A., Zorn M., Liesz A., Veltkamp R. Usefulness of serum procalcitonin levels for the early diagnosis of stroke-associated respiratory tract infections. Neurocrit Care 2011, 14:416-422.
33. Schuetz P., Christ-Crain M., Thomann R., et al. Effect of procalcitonin-based guidelines vs standard guidelines on antibiotic use in lower respiratory tract infections: the ProHOSP randomized controlled trial. JAMA 2009, 302:1059-1066.
34. Goto T., Hazui H., Hoshiga M., et al. Bacterial translocation after mild therapeutic hypothermia. Resuscitation 2009, 80:960.
35. Hebra A., Hong J., McGowan K.L., Smith C., McKernan M.L., Ross A.J. Bacterial translocation in mesenteric ischemia-reperfusion injury: is dysfunctional motility the link?. J Pediatr Surg 1994, 29:280-285. discussion 5-7.
36. Geppert A., Steiner A., Delle-Karth G., Heinz G., Huber K. Usefulness of procalcitonin for diagnosing complicating sepsis in patients with cardiogenic shock. Intensive Care Med 2003, 29:1384-1389.
37. Schuetz P., Christ-Crain M., Huber A.R., Muller B. Long-term stability of procalcitonin in frozen samples and comparison of Kryptor and VIDAS automated immunoassays. Clin Biochem 2010, 43:341-344.