The influence of induced hypothermia and delayed prognostication on the mode of death after cardiac arrest

Resuscitation

Volumn 84, Issue 3, 2013, Pages 337-342

  Dragancea, Irina ^a   Rundgren, Malin ^a   Englund, Elisabet ^a   Friberg, Hans ^a   Cronberg, Tobias ^a  

^a LUND UNIVERSITY HOSPITAL   (Sweden)

Author keywords

Cardiac arrest; Hypothermia; Mode of death; Neurological prognostication

Indexed keywords

ADOLESCENT; ADULT; AGED; ARTICLE; BRAIN DEATH; BRAIN INJURY; CAUSE OF DEATH; CEREBRAL PERFORMANCE CATEGORIES SCALE; DECISION MAKING; FEMALE; HEART ARREST; HOSPITAL DISCHARGE; HUMAN; INDUCED HYPOTHERMIA; INTENSIVE CARE; LUNG COMPLICATION; MAJOR CLINICAL STUDY; MALE; OBSERVATIONAL STUDY; ORGAN DONOR; PERSISTENT VEGETATIVE STATE; PRIORITY JOURNAL; PROGNOSIS; RATING SCALE; RETROSPECTIVE STUDY; SURVIVOR; WARMING;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; BRAIN ISCHEMIA; CAUSE OF DEATH; COMA; FEMALE; HEART ARREST; HUMANS; HYPOTHERMIA, INDUCED; INCIDENCE; MALE; MIDDLE AGED; PERSISTENT VEGETATIVE STATE; PROGNOSIS; RETROSPECTIVE STUDIES; SURVIVAL RATE; SWEDEN; TREATMENT OUTCOME; YOUNG ADULT;

EID: 84875056069     PISSN: 03009572     EISSN: 18731570     Source Type: Journal    
DOI: 10.1016/j.resuscitation.2012.09.015     Document Type: Article

References (35)

1. Atwood C., Eisenberg M.S., Herlitz J., Rea T.D. Incidence of EMS-treated out-of-hospital cardiac arrest in Europe. Resuscitation 2005, 67:75-80.
2. Adielsson A., Hollenberg J., Karlsson T., et al. Increase in survival and bystander CPR in out-of-hospital shockable arrhythmia: bystander CPR and female gender are predictors of improved outcome. Experiences from Sweden in an 18-year perspective. Heart 2011, 97:1391-1396.
3. Lund-Kordahl I., Olasveengen T.M., Lorem T., Samdal M., Wik L., Sunde K. Improving outcome after out-of-hospital cardiac arrest by strengthening weak links of the local Chain of Survival; quality of advanced life support and post-resuscitation care. Resuscitation 2010, 81:422-426.
4. Holmberg M., Holmberg S., Herlitz J. Effect of bystander cardiopulmonary resuscitation in out-of-hospital cardiac arrest patients in Sweden. Resuscitation 2000, 47:59-70.
5. Nichol G., Karmy-Jones R., Salerno C., Cantore L., Becker L. Systematic review of percutaneous cardiopulmonary bypass for cardiac arrest or cardiogenic shock states. Resuscitation 2006, 70:381-394.
6. Sunde K., Pytte M., Jacobsen D., et al. Implementation of a standardised treatment protocol for post resuscitation care after out-of-hospital cardiac arrest. Resuscitation 2007, 73:29-39.
7. Mild therapeutic hypothermia to improve the neurologic outcome after cardiac arrest. N Engl J Med 2002, 346:549-556.
8. Bernard S.A., Gray T.W., Buist M.D., et al. Treatment of comatose survivors of out-of-hospital cardiac arrest with induced hypothermia. N Engl J Med 2002, 346:557-563.
9. Herlitz J., Engdahl J., Svensson L., Angquist K.A., Silfverstolpe J., Holmberg S. Major differences in 1-month survival between hospitals in Sweden among initial survivors of out-of-hospital cardiac arrest. Resuscitation 2006, 70:404-409.
10. Langhelle A., Tyvold S.S., Lexow K., Hapnes S.A., Sunde K., Steen P.A. In-hospital factors associated with improved outcome after out-of-hospital cardiac arrest. A comparison between four regions in Norway. Resuscitation 2003, 56:247-263.
11. Nolan J.P., Laver S.R., Welch C.A., Harrison D.A., Gupta V., Roman K. Outcome following admission to UK intensive care units after cardiac arrest: a secondary analysis of the ICNARC Case Mix Programme Database. Anaesthesia 2007, 62:1207-1216.
12. Brain Resuscitation Clinical Trial I Study Group Randomized clinical study of thiopental loading in comatose survivors of cardiac arrest. N Engl J Med 1986, 314:397-403.
13. Brain Resuscitation Clinical Trial II Study Group A randomized clinical study of a calcium-entry blocker (lidoflazine) in the treatment of comatose survivors of cardiac arrest. N Engl J Med 1991, 324:1225-1231.
14. Laver S., Farrow C., Turner D., Nolan J. Mode of death after admission to an intensive care unit following cardiac arrest. Intensive Care Med 2004, 30:2126-2128.
15. Olasveengen T.M., Sunde K., Brunborg C., Thowsen J., Steen P.A., Wik L. Intravenous drug administration during out-of-hospital cardiac arrest: a randomized trial. JAMA 2009, 302:2222-2229.
16. Cronberg T., Lilja G., Rundgren M., Friberg H., Widner H. Long-term neurological outcome after cardiac arrest and therapeutic hypothermia. Resuscitation 2009, 80:1119-1123.
17. Che D., Li L., Kopil C.M., Liu Z., Guo W., Neumar R.W. Impact of therapeutic hypothermia onset and duration on survival, neurologic function, and neurodegeneration after cardiac arrest. Crit Care Med 2011, 39:1423-1430.
18. Deakin C.D., Nolan J.P., Soar J., et al. European Resuscitation Council Guidelines for Resuscitation 2010 Section 4. Adult advanced life support. Resuscitation 2010, 81:1305-1352.
19. Peberdy M.A., Callaway C.W., Neumar R.W., et al. Part 9: post-cardiac arrest care: 2010 American Heart Association Guidelines for Cardiopulmonary Resuscitation and Emergency Cardiovascular Care. Circulation 2010, 122:S768-S786.
20. Wijdicks E.F., Hijdra A., Young G.B., Bassetti C.L., Wiebe S. Practice parameter: prediction of outcome in comatose survivors after cardiopulmonary resuscitation (an evidence-based review): report of the Quality Standards Subcommittee of the American Academy of Neurology. Neurology 2006, 67:203-210.
21. Samaniego E.A., Mlynash M., Caulfield A.F., Eyngorn I., Wijman C.A. Sedation confounds outcome prediction in cardiac arrest survivors treated with hypothermia. Neurocrit Care 2011, 15:113-119.
22. Tortorici M.A., Kochanek P.M., Poloyac S.M. Effects of hypothermia on drug disposition, metabolism, and response: a focus of hypothermia-mediated alterations on the cytochrome P450 enzyme system. Crit Care Med 2007, 35:2196-2204.
23. Webb A.C., Samuels O.B. Reversible brain death after cardiopulmonary arrest and induced hypothermia. Crit Care Med 2011, 39:1538-1542.
24. Cronberg T., Rundgren M., Westhall E., et al. Neuron-specific enolase correlates with other prognostic markers after cardiac arrest. Neurology 2011, 77:623-630.
25. Rundgren M., Westhall E., Cronberg T., Rosen I., Friberg H. Continuous amplitude-integrated electroencephalogram predicts outcome in hypothermia-treated cardiac arrest patients. Crit Care Med 2010, 38:1838-1844.
26. Jennett B., Bond M. Assessment of outcome after severe brain damage. Lancet 1975, 1:480-484.
27. Socialstyrelsens föreskrifter och allmänna råd om kriterier för bestämmande av människans död. Svensk författningssamling SOSFS (Swedish Statute book SOSFS) Directions and recommendations from the National Board of Health and Welfare in Sweden concerning criteria for determination of death. 2005; 10.
28. Jörgensen E.O., Holm S. The natural course of neurological recovery following cardiopulmonary resuscitation. Resuscitation 1998, 36:111-122.
29. Rossetti A.O., Oddo M., Logroscino G., Kaplan P.W. Prognostication after cardiac arrest and hypothermia: a prospective study. Ann Neurol 2010, 67:301-307.
30. Fugate J.E., Wijdicks E.F., White R.D., Rabinstein A.A. Does therapeutic hypothermia affect time to awakening in cardiac arrest survivors?. Neurology 2011, 77:1346-1350.
31. Nielsen N., Hovdenes J., Nilsson F., et al. Outcome, timing and adverse events in therapeutic hypothermia after out-of-hospital cardiac arrest. Acta Anaesthesiol Scand 2009, 53:926-934.
32. Al Thenayan E., Savard M., Sharpe M., Norton L., Young B. Predictors of poor neurologic outcome after induced mild hypothermia following cardiac arrest. Neurology 2008, 71:1535-1537.
33. Lucas J.M., Cocchi M.N., Salciccioli J., et al. Neurologic recovery after therapeutic hypothermia in patients with post-cardiac arrest myoclonus. Resuscitation 2011.
34. Rossetti A.O., Oddo M., Liaudet L., Kaplan P.W. Predictors of awakening from postanoxic status epilepticus after therapeutic hypothermia. Neurology 2009, 72:744-749.
35. Organ Procurement and Transplantation Network: deceased donors recovered in US with anoxia as cause of death. Available at: [accessed 29.7.12]. http://optn.transplant.hrsa.gov/.