Neuron-specific enolase correlates with other prognostic markers after cardiac arrest

Neurology

Volumn 77, Issue 7, 2011, Pages 623-630

  Cronberg, T ^a   Rundgren, M ^b   Westhall, E ^b   Englund, E ^b   Siemund, R ^b   Rosen I ^b   Widner, H ^a   Friberg, H ^b  

^a LUND UNIVERSITY HOSPITAL   (Sweden)

^b LUND UNIVERSITY   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

NEURON SPECIFIC ENOLASE; BIOLOGICAL MARKER; ENOLASE;

ADULT; AGED; AROUSAL; ARTICLE; AUTOPSY; BODY TEMPERATURE; BRAIN CORTEX; BRAIN ISCHEMIA; CARDIAC PATIENT; COMA; CONSCIOUSNESS LEVEL; CONVALESCENCE; DIFFUSION WEIGHTED IMAGING; DISEASE SEVERITY; ELECTROENCEPHALOGRAPHY; ENZYME BLOOD LEVEL; EPILEPTIC STATE; EVOKED SOMATOSENSORY RESPONSE; FEMALE; FOLLOW UP; HEART ARREST; HISTOPATHOLOGY; HUMAN; INDUCED HYPOTHERMIA; INTENSIVE CARE; LONG TERM CARE; MAJOR CLINICAL STUDY; MALE; NUCLEAR MAGNETIC RESONANCE IMAGING; OBSERVATIONAL STUDY; PRIORITY JOURNAL; PROGNOSIS; PROSPECTIVE STUDY; VERBAL COMMUNICATION; BLOOD; MIDDLE AGED; PREDICTIVE VALUE; RESUSCITATION;

AGED; BIOLOGICAL MARKERS; CARDIOPULMONARY RESUSCITATION; COMA; FEMALE; HEART ARREST; HUMANS; HYPOTHERMIA, INDUCED; MALE; MIDDLE AGED; PHOSPHOPYRUVATE HYDRATASE; PREDICTIVE VALUE OF TESTS; PROGNOSIS; PROSPECTIVE STUDIES;

EID: 80055085732     PISSN: 00283878     EISSN: 1526632X     Source Type: Journal    
DOI: 10.1212/WNL.0b013e31822a276d     Document Type: Article

References (33)

1. Edgren E, Hedstrand U, Kelsey S, Sutton-Tyrrell K, Safar P. Assessment of neurological prognosis in comatose survivors of cardiac arrest. Lancet 1994;343:1055-1059. (Pubitemid 24128203)
2. Levy DE, Caronna JJ, Singer BH, Lapinski RH, Frydman H, Plum F. Predicting outcome from hypoxic-ischemic coma. JAMA 1985;253:1420-1426. (Pubitemid 15128803)
3. Zandbergen EG, de Haan RJ, Stoutenbeek CP, Koelman JH, Hijdra A. Systematic review of early prediction of poor outcome in anoxic-ischaemic coma. Lancet 1998;352: 1808-1812. (Pubitemid 28550069)
4. Zandbergen EG, Hijdra A, Koelman JH, et al. Prediction of poor outcome within the first 3 days of postanoxic coma. Neurology 2006;66:62-68. (Pubitemid 43739593)
5. Young GB. The EEG in coma. J Clin Neurophysiol 2000; 17:473-485.
6. Rossetti AO, Urbano LA, Delodder F, Kaplan PW, Oddo M. Prognostic value of continuous EEG monitoring during therapeutic hypothermia after cardiac arrest. Crit Care 2010;14:R173.
7. Reisinger J, Siostrzonek P. Prediction of neurological outcome after cardiopulmonary resuscitation. Eur Heart J 2007;28:2415. (Pubitemid 47537779)
8. Rundgren M, Karlsson T, Nielsen N, Cronberg T, Johnsson P, Friberg H. Neuron specific enolase and S-100B as predictors of outcome after cardiac arrest and induced hypothermia. Resuscitation 2009;80:784-789.
9. Tiainen M, Roine RO, Pettila V, Takkunen O. Serum neuron-specific enolase and S-100B protein in cardiac arrest patients treated with hypothermia. Stroke 2003;34: 2881-2886. (Pubitemid 37517761)
10. Wijdicks EF, Campeau NG, Miller GM. MR imaging in comatose survivors of cardiac resuscitation. Am J Neuroradiol 2001;22:1561-1565. (Pubitemid 32862269)
11. Järnum H, Knutsson L, Rundgren M, et al. Diffusion and perfusion MRI of the brain in comatose patients treated with mild hypothermia after cardiac arrest: a prospective observational study. Resuscitation 2009;80:425-430.
12. HACA: Hypothermia After Cardiac Arrest Study Group. Mild therapeutic hypothermia to improve the neurologic outcome after cardiac arrest. N Engl J Med 2002;346: 549-556.
13. Bernard SA, Gray TW, Buist MD, et al. Treatment of comatose survivors of out-of-hospital cardiac arrest with induced hypothermia. N Engl J Med 2002;346:557-563. (Pubitemid 34438816)
14. Peberdy MA, Callaway CW, Neumar RW, et al. Part 9: post-cardiac arrest care: 2010 American Heart Association Guidelines for Cardiopulmonary Resuscitation and Emergency Cardiovascular Care. Circulation 2010;122:S768-786.
15. Nolan JP, Soar J, Zideman DA, et al. European Resuscitation Council Guidelines for Resuscitation 2010: section 1: executive summary. Resuscitation 2010;81:1219-1276.
16. Tortorici MA, Kochanek PM, Poloyac SM. Effects of hypothermia on drug disposition, metabolism, and response: a focus of hypothermia-mediated alterations on the cytochrome P450 enzyme system. Crit Care Med 2007;35: 2196-2204. (Pubitemid 47326460)
17. Al Thenayan E, Savard M, Sharpe M, Norton L, Young B. Predictors of poor neurologic outcome after induced mild hypothermia following cardiac arrest. Neurology 2008;71: 1535-1537.
18. Holzer M. Targeted temperature management for comatose survivors of cardiac arrest. N Engl J Med 2010;363: 1256-1264.
19. Wijdicks EF, Hijdra A, Young GB, Bassetti CL, Wiebe S. Practice parameter: prediction of outcome in comatose survivors after cardiopulmonary resuscitation (an evidence-based review): report of the Quality Standards Subcommittee of the American Academy of Neurology. Neurology 2006;67:203-210. (Pubitemid 44305400)
20. Bouwes A, Binnekade JM, Zandstra DF, et al. Somatosensory evoked potentials during mild hypothermia after cardiopulmonary resuscitation. Neurology 2009;73: 1457-1461.
21. Tiainen M, Kovala TT, Takkunen OS, Roine RO. Somatosensory and brainstem auditory evoked potentials in cardiac arrest patients treated with hypothermia. Crit Care Med 2005;33:1736-1740. (Pubitemid 41153698)
22. Oksanen T, Tiainen M, Skrifvars MB, et al. Predictive power of serum NSE and OHCA score regarding 6-month neurologic outcome after out-of-hospital ventricular fibrillation and therapeutic hypothermia. Resuscitation 2009; 80:165-170.
23. Leithner C, Ploner CJ, Hasper D, Storm C. Does hypothermia influence the predictive value of bilateral absent N20 after cardiac arrest? Neurology 2010;74:965-969.
24. Fugate JE, Wijdicks EF, Mandrekar J, et al. Predictors of neurologic outcome in hypothermia after cardiac arrest. Ann Neurol 2010;68:904-914.
25. Steffen IG, Hasper D, Ploner CJ, et al. Mild therapeutic hypothermia alters neuron specific enolase as an outcome predictor after resuscitation: 97 prospective hypothermia patients compared to 133 historical non-hypothermia patients. Crit Care 2010;14:R69.
26. Rundgren M, Rosen I, Friberg H. Amplitude-integrated EEG (aEEG) predicts outcome after cardiac arrest and induced hypothermia. Intens Care Med 2006;32:836-842. (Pubitemid 43781364)
27. Rundgren M, Westhall E, Cronberg T, Rosén I, Friberg H. Continuous amplitude integrated EEG predicts outcome in hypothermia treated cardiac arrest patients. Crit Care Med 2010;38:1838 -1844.
28. Rossetti AO, Oddo M, Liaudet L, Kaplan PW. Predictors of awakening from postanoxic status epilepticus after therapeutic hypothermia. Neurology 2009;72:744-749.
29. Rossetti AO, Oddo M, Logroscino G, Kaplan PW. Prognostication after cardiac arrest and hypothermia: a prospective study. Ann Neurol 2010;67:301-307.
30. Cronberg T, Lilja G, Rundgren M, Friberg H, Widner H. Long-term neurological outcome after cardiac arrest and therapeutic hypothermia. Resuscitation 2009;80:1119-1123.
31. Pulsinelli WA, Brierley JB, Plum F. Temporal profile of neuronal damage in a model of transient forebrain ischemia. Ann Neurol 1982;11:491-498. (Pubitemid 12158810)
32. Petito CK, Feldmann E, Pulsinelli WA, Plum F. Delayed hippocampal damage in humans following cardiorespiratory arrest. Neurology 1987;37:1281-1286.
33. Stern P, Bartos V, Uhrova J, et al. Performance characteristics of seven neuron-specific enolase assays. Tumour Biol 2007;28:84-92. (Pubitemid 46328596)