Amelioration of palmitate-induced insulin resistance in C2C12 muscle cells by rooibos (Aspalathus linearis)

Phytomedicine

Volumn 20, Issue 10, 2013, Pages 813-819

  Mazibuko, S E ^a,b   Muller, C J F ^a   Joubert, E ^c,d   De Beer, D ^c   Johnson, R ^a   Opoku, A R ^b   Louw, J ^a  

^a SOUTH AFRICAN MEDICAL RESEARCH COUNCIL   (South Africa)

^b UNIVERSITY OF ZULULAND   (South Africa)

^c AGRICULTURAL RESEARCH COUNCIL   (South Africa)

^d STELLENBOSCH UNIVERSITY   (South Africa)

Author keywords

Aspalathin; Aspalathus linearis; Glucose uptake; Insulin resistance; Palmitate; Rooibos

Indexed keywords

ADENYLATE KINASE; GLUCOSE; GLUCOSE TRANSPORTER 4; LUTEOLIN 7 GLUCOSIDE; PALMITIC ACID; PHENYLPYRUVIC ACID; PROTEIN KINASE B;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; ASPALATHUS; ASPALATHUS LINEARIS; CONTROLLED STUDY; GLUCOSE BLOOD LEVEL; GLUCOSE METABOLISM; GLUCOSE TRANSPORT; IN VITRO STUDY; IN VIVO STUDY; INSULIN RESISTANCE; MOUSE; MUSCLE CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SKELETAL MUSCLE; WESTERN BLOTTING;

3-(4,5-DIMETHYLTHIAZOL-2-YL)-2,5-DIPHENYLTETRAZOLIUM BROMIDE; 5′ ADENOSINE MONOPHOSPHATE-ACTIVATED PROTEIN KINASE; ADENOSINE TRIPHOSPHATE; AKT; AMPK; ASPALATHIN; ASPALATHIN-ENRICHED GREEN ROOIBOS EXTRACT; ASPALATHUS LINEARIS; ATP; BOVINE SERUM ALBUMIN; BSA; DAG; DIACYLGLYCEROL; DMEM; DPBS; DULBECCO'S MODIFIED EAGLE MEDIUM; DULBECCO'S PHOSPHATE BUFFERED SALINE; FCS; FERMENTED ROOIBOS EXTRACT; FETAL CALF SERUM; FFAS; FRE; FREE FATTY ACIDS; GLUCOSE TRANSPORTER TYPE 4; GLUCOSE UPTAKE; GLUT4; GRE; HIGH-PERFORMANCE LIQUID CHROMATOGRAPHY WITH DIODE-ARRAY DETECTION; HORSERADISH PEROXIDISE; HPLC-DAD; HPR; IGG; IMMUNOGLOBULIN G; INSULIN RECEPTOR SUBSTRATE 1; INSULIN RESISTANCE; IR; IRS1; MTT; PAKT; PALMITATE; PAMPK; PHENYLMETHANESULFONYLFLUORIDE; PHOSPHORYLATED 5′ ADENOSINE MONOPHOSPHATE-ACTIVATED PROTEIN KINASE; PHOSPHORYLATED PROTEIN KINASE; PHOSPHORYLATED PROTEIN KINASE C THETA; PKC Θ; PMSF; PPKC Θ; PROTEIN KINASE B; PROTEIN KINASE C THETA; RIBONUCLEASE; RNASE; ROOIBOS; T2D; TAKT; TAMPK; TBST; TOTAL 5′ ADENOSINE MONOPHOSPHATE-ACTIVATED PROTEIN KINASE; TOTAL PROTEIN KINASE B; TOTAL PROTEIN KINASE C THETA; TPKC Θ; TRIS-BUFFERED SALINE WITH TWEEN; TYPE 2 DIABETES;

ANIMALS; ASPALATHUS; CELL LINE; HYPERINSULINISM; INSULIN RESISTANCE; MICE; MUSCLE, SKELETAL; PALMITIC ACID; PHYTOTHERAPY; PLANT EXTRACTS;

ASPALATHUS LINEARIS; RATTUS;

EID: 84879885429     PISSN: 09447113     EISSN: 1618095X     Source Type: Journal    
DOI: 10.1016/j.phymed.2013.03.018     Document Type: Article

References (36)

1. M.A. Abdul-Ghani, and R.A. DeFronzo Pathogenesis of insulin resistance in skeletal muscle Journal of Biomedicine and Biotechnology 2010 1 19 10.1155/2010/4762790 2010
2. A.J. Alonso-Castro, R. Zapata-Bustos, G. Gómez-Espinoza, and L.A. Salazar-Olivo Isoorientin reverts TNF-α-induced insulin resistance in adipocytes activating the insulin signaling pathway Endocrinology 153 2011 5222 5230
3. G.F. Anhê, M.M. Okamoto, A. Kinote, A. Sollon, C. Lellis-Santos, F.F. Anhê, G.A. Lima, S.M. Hirabara, L.A. Velloso, S. Bordin, and U.F. Machado Quercetin decreases inflammatory response and increases insulin action in skeletal muscle of ob/ob mice and in L6 myotubes European Journal of Pharmacology 689 2012 285 293
4. R. Beltrán-Debón, A. Rull, F. Rodríguez-Sanabria, I. Iswaldi, M. Herranz-López, G. Aragonès, J. Camps, C. Alonso-Villaverde, J.A. Menéndez, V. Micol, A. Segura-Carretero, and J. Joven Continuous administration of polyphenols from aqueous rooibos (Aspalathus linearis) extract ameliorates dietary-induced metabolic disturbances in hyperlipidaemic mice Phytomedicine 18 2011 414 424
5. S. Bhattacharya, D. Dey, and S.S. Roy Molecular mechanism of insulin resistance Journal of Bioscience 32 2007 405 413
6. G. Boden, X. Chen, J. Ruiz, J.V. White, and L. Rosseti Mechanism of fatty acid-induced inhibition of glucose uptake Journal of Clinical Investigation 93 1993 2438 2446
7. K. Bouzakri, A. Zachrisson, L. Al-Khalili, B.B. Zhang, H.A. Koistinen, A. Krook, and J.R. Zierath siRNA-based gene silencing reveals specialized roles of IRS-1/Akt2 and IRS-2/Akt1 in glucose and lipid metabolism in human skeletal muscle Cell Metabolism 4 2006 89 96
8. E. Cersosimo, and J.E. Dutra de Oliveira Nutrology and type 2 diabetes: nutrient pathophysiology and the transition from health to disease International Journal of Nutrology 5 2012 6 13
9. 2+ in pancreatic cell death induced by alcohol metabolites Journal of Gastroenterology and Hepatology 3 2006 14 17
10. R.A. DeFronzo, and D. Tripathy Skeletal muscle insulin resistance is the primary defect in type 2 diabetes Diabetes Care 32 2009 S157 S163
11. Y.T. Deng, T.W. Chang, M.S. Lee, and J.K. Lin Suppression of free fatty acid-induced insulin resistance by phytopolyphenols in C2C12 mouse skeletal muscle cells Journal of Agricultural and Food Chemistry 60 2012 1059 1066
12. N. Dimopoulos, M. Watson, K. Sakamoto, and H.S. Hundal Differential effects of palmitate and palmitoleate on insulin action and glucose utilisation in rat L6 skeletal muscle cells Biochemical Journal 399 2006 473 481
13. A.K. Dutta-Roy Cellular uptake of long-chain fatty acids: role of membrane-associated fatty-acid-binding/transport proteins Cellular and Molecular Life Sciences 57 2000 1360 1372
14. H.M. Eid, L.C. Martineau, A. Saleem, A. Muhammad, D. Vallerand, A. Benhaddou-Andaloussi, L. Nistor, A. Afshar, J.T. Arnason, and P.S. Haddad Stimulation of AMP-activated protein kinase and enhancement of basal glucose uptake in muscle cells by quercetin and quercetin glycosides, active principles of the antidiabetic medicinal plant Vaccinium vitis-idaea Molecular Nutrition Food Research Journal 54 2010 991 1003
15. J. Eriksson, J. Lindström, and J. Tuomilehto Potential for the prevention of type 2 diabetes British Medical Bulletin 60 2001 183 199
16. J.F.C. Glatz, J.J.F.P. Luiken, and A. Bonen Membrane fatty acid transporters as regulators of lipid metabolism: implications for metabolic disease Physiological Reviews 90 2010 367 417
17. Grüner-Richter, S., Otto, F., Weinreich, B., 2008. Rooibos extract with increased aspalathin content, process for the preparation of such a rooibos extract, and cosmetic agent containing such a rooibos extract. US Patent Application No. US2008/0247974 A1.
18. F.B. Hu Globalization of diabetes: the role of diet, lifestyle, and genes Diabetes Care 34 2011 1249 1257
19. E. Joubert, and D. De Beer Rooibos (Aspalathus linearis) beyond the farm gate: from herbal tea to potential phytopharmaceutical South African Journal of Botany 77 2011 869 886
20. E. Joubert, W.C.A. Gelderblom, J. Louw, and D. De Beer South African herbal teas: Aspalathus linearis, Cyclopia spp. and Athrixia phylicoides - a review Journal of Ethnopharmacology 119 2008 376 412
21. M. Jové, A. Planavila, R.M. Sánchez, M. Merlos, J.C. Laguna, and M. Vázquez-Carrera Palmitate induces tumor necrosis factor-α expression in C2C12 skeletal muscle cells by a mechanism involving protein kinase C and nuclear factor-κB activation Endocrinology 147 2006 552 561
22. A. Kawano, H. Nakamura, S. Hata, M. Minakawa, Y. Miura, and K. Yagasaki Hypoglycemic effect of aspalathin, a rooibos tea component from Aspalathus linearis, in type 2 diabetic model db/db mice Phytomedicine 16 2009 437 443
23. C. Lee, W. Hsu, S. Shen, Y. Cheng, and S. Wu Fagopyrum tataricum (Buckwheat) improved high-glucose-induced insulin resistance in mouse hepatocytes and diabetes in fructose-rich diet-induced mice Experimental Diabetes Research 2012 2012 1 10 10.1155/2012/375673
24. H.M.T. Mossman Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxic assays Journal of Immunological Methods 65 1983 55 63
25. C.J.F. Muller, E. Joubert, D. De Beer, M. Sanderson, C.J. Malherbe, S.J. Fey, and J. Louw Acute assessment of an aspalathin-enriched green rooibos (Aspalathus linearis) extract with hypoglycaemic potential Phytomedicine 20 2012 32 39
26. M. Prashanth, H.K. Ganesh, M. Vimal, M. John, T. Bandgar, S.R. Joshi, and S.R. Shah Prevalence of nonalcoholic fatty liver disease in patients with Type 2 diabetes mellitus Journal of the Association of Physicians of India 57 2009 205 210
27. R. Ragheb, and A.M. Medhat Mechanisms of fatty acid-induced insulin resistance in muscle and liver Journal of Diabetes and Metabolism 2 2011 1 5
28. M.P. Sajan, G. Bandyopadhyay, A. Miura, M.L. Standaert, S. Nimal, S.L. Longnus, E. Van Obberghen, I. Hainault, F. Foufelle, R. Kahn, U. Braun, M. Leitges, and R.V. Farese AICAR and metformin, but not exercise, increase muscle glucose transport through AMPK-, ERK-, and PDK1-dependent activation of atypical PKC American Journal of Physiology - Endocrinology and Metabolism 298 2010 E179 E192
29. M.K. Son, M. Minakawa, M. Miura, and K. Yagasaki Aspalathin improves hyperglycemia and glucose intolerance in obese diabetic ob/ob mice The European Journal of Nutrition 2012 1 13 10.1007/s00394-012-0466-6
30. Y. Song, J. Li, Y. Zhao, Q. Zhang, Z. Lui, J. Li, X. Chen, Z. Yang, C. Yu, and X. Xiao Severe maternal hyperglycemia exacerbates the development of insulin resistance and fatty liver in the offspring on high fat diet Experimental Diabetes Research 2012 2012 1 8 10.1155/2012/254976
31. E.H. Walker, M.E. Pacold, O. Perisic, L. Stephens, P.T. Hawkins, M.P. Waymann, and R.L. Williams Structural determinants of phosphoinositide 3-kinase inhibition by wortmannin, LY294002, quercetin, myricetin, and staurosporine Molecular Cell 6 2000 909 919
32. C. Weigert, K. Klopfer, C. Kausch, K. Brodbeck, M. Stumvoll, H.U. Harring, and E.D. Scheleicher Palmitate-induced activation of the hexosamine pathway in human myotubes Diabetes 52 2003 650 656
33. G. Wilcox Insulin and insulin resistance The Clinical Biochemist Reviews 26 2005 19 39
34. K.N. Wisman, A.A. Perkins, M.D. Jeffers, and A.E. Hagerman Accurate assessment of the bioactivities of redox-active polyphenolic in cell culture Journal of Agricultural and Food Chemistry 56 2008 7831 7833
35. C. Wu, M. Lin, H. Wang, M. Yang, M. Jou, and C. Wang Rutin inhibits oleic acid induced lipid accumulation via reducing lipogenesis and oxidative stress in hepatocarcinoma cells Journal of Food Science 72 2011 T71 T72
36. L. Yuzefovych, G. Wilson, and L. Rachek Different effects of oleate vs. palmitate on mitochondrial function, apoptosis, and insulin signaling in L6 skeletal muscle cells: role of oxidative stress American Journal of Physiology - Endocrinology and Metabolism 299 2010 E1096 E1105