SCOPUS 정보 검색 플랫폼

Volumn 19, Issue 28, 2013, Pages 9343-9350

Multistep continuous-flow synthesis in medicinal chemistry: Discovery and preliminary structure-activity relationships of CCR8 ligands

(7) Petersen, Trine P a,b Mirsharghi, Sahar a Rummel, Pia C c Thiele, Stefanie c Rosenkilde, Mette M c Ritzén, Andreas b,d Ulven, Trond a

a UNIVERSITY OF SOUTHERN DENMARK (Denmark)

b H LUNDBECK A S (Denmark)

c UNIVERSITY OF COPENHAGEN (Denmark)

d LEO PHARMA A S (Denmark)

Author keywords

chemokine receptor ligands; flow chemistry; medicinal chemistry; small molecule agonist; structure activity relationships

Indexed keywords

CHEMOKINE RECEPTORS; FLOW CHEMISTRY; MEDICINAL CHEMISTRY; SMALL MOLECULES; STRUCTURE ACTIVITY RELATIONSHIPS;

LIGANDS; OFFICE BUILDINGS;

CHELATION;

CCR8 PROTEIN, HUMAN; CHEMOKINE RECEPTOR CCR8; INOSITOL PHOSPHATE; LIGAND; NAPHTHALENE DERIVATIVE; PIPERAZINE DERIVATIVE;

ANIMAL; ARTICLE; CELL STRAIN COS1; CHEMISTRY; CHEMOKINE RECEPTOR LIGANDS; CHLOROCEBUS AETHIOPS; DRUG POTENTIATION; FLOW CHEMISTRY; GENETICS; HUMAN; MEDICINAL CHEMISTRY; METABOLISM; PROTEIN BINDING; SMALL MOLECULE AGONIST; STEREOISOMERISM; STRUCTURE ACTIVITY RELATION; STRUCTURE-ACTIVITY RELATIONSHIPS; SYNTHESIS;

CHEMOKINE RECEPTOR LIGANDS; FLOW CHEMISTRY; MEDICINAL CHEMISTRY; SMALL MOLECULE AGONIST; STRUCTURE-ACTIVITY RELATIONSHIPS;

ANIMALS; CERCOPITHECUS AETHIOPS; COS CELLS; HUMANS; INOSITOL PHOSPHATES; LIGANDS; NAPHTHALENES; PIPERAZINES; PROTEIN BINDING; RECEPTORS, CCR8; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84879883941 PISSN: 09476539 EISSN: 15213765 Source Type: Journal
DOI: 10.1002/chem.201204350 Document Type: Article

Times cited : (22)

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