Selenoprotein P and selenoprotein M block Zn2+-mediated Aβ42 aggregation and toxicity

Metallomics

Volumn 5, Issue 7, 2013, Pages 861-870

  Du, Xiubo ^a   Li, Haiping ^b   Wang, Zhi ^a   Qiu, Shi ^b   Liu, Qiong ^b   Ni, Jiazuan ^a  

^a SHENZHEN UNIVERSITY   (China)

^b The Key Laboratory for Marine Bioresource and Eco environmental Science   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ALZHEIMER'S DISEASE; BINDING TRANSITION; INCURABLE DISEASE; METAL HOMEOSTASIS; REACTIVE OXYGEN SPECIES; STRUCTURAL CHANGE; SUB-MICROMOLAR AFFINITY; THERAPEUTIC STRATEGY;

AMINO ACIDS; METAL IONS; PROTEINS; REDOX REACTIONS; TOXICITY; TRANSMISSION ELECTRON MICROSCOPY;

ZINC;

AMYLOID BETA PROTEIN[1-42]; CADMIUM; HISTIDINE; REACTIVE OXYGEN METABOLITE; SELENOCYSTEINE; SELENOPROTEIN; SELENOPROTEIN M; SELENOPROTEIN P; THIOFLAVINE; UNCLASSIFIED DRUG; ZINC ION;

ALZHEIMER DISEASE; AMINO ACID SEQUENCE; ANIMAL CELL; ARTICLE; CELL CULTURE; CIRCULAR DICHROISM; HOMEOSTASIS; ISOTHERMAL TITRATION CALORIMETRY; METAL BINDING; MOUSE; NERVE CELL; NEUROTOXICITY; NONHUMAN; OXIDATION REDUCTION REACTION; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN BINDING; PROTEIN FUNCTION; PROTEIN MOTIF; PROTEIN STRUCTURE; TRANSMISSION ELECTRON MICROSCOPY;

AMINO ACID SEQUENCE; AMYLOID BETA-PEPTIDES; BASE SEQUENCE; CIRCULAR DICHROISM; DNA PRIMERS; ESCHERICHIA COLI; MICROSCOPY, ELECTRON, TRANSMISSION; MOLECULAR SEQUENCE DATA; SELENOPROTEIN P; SELENOPROTEINS; SEQUENCE HOMOLOGY, AMINO ACID; SPECTROPHOTOMETRY, ULTRAVIOLET; ZINC;

EID: 84879861295     PISSN: 17565901     EISSN: 1756591X     Source Type: Journal    
DOI: 10.1039/c3mt20282h     Document Type: Article

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