Genomic and expression analysis of the vanG-like gene cluster of Clostridium difficile

Microbiology (United Kingdom)

Volumn 159, Issue PART7, 2013, Pages 1510-1520

  Peltier, Johann ^a   Courtin, Pascal ^b   El Meouche, Imane ^a   Catel Ferreira, Manuella ^c   Chapot Chartier, Marie Pierre ^b   Lemée, Ludovic ^a   Pons, Jean Louis ^d  

^a UNIVERSITÉ DE ROUEN   (France)

^b UMR1319 MICALIS   (France)

^c UNIVERSITÉ DE ROUEN   (France)

^d UNIVERSITÉ PARIS DESCARTES   (France)

Author keywords

[No Author keywords available]

Indexed keywords

TEICOPLANIN; VANCOMYCIN;

AMINO ACID SEQUENCE; ANTIBIOTIC RESISTANCE; ANTIBIOTIC SENSITIVITY; ARTICLE; BACTERIAL CELL WALL; BACTERIAL GENETICS; BACTERIAL GROWTH; CLOSTRIDIUM DIFFICILE; CONTROLLED STUDY; DNA SEQUENCE; GENE CLUSTER; GENE EXPRESSION; GENE INACTIVATION; GENETIC ORGANIZATION; GENETIC TRANSCRIPTION; HYDROPHILIC INTERACTION CHROMATOGRAPHY; INVERTED REPEAT; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; OPERON; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN SECONDARY STRUCTURE; REGULATOR GENE; STOP CODON; TRANSPOSON;

ANTI-BACTERIAL AGENTS; BACTERIAL PROTEINS; CLOSTRIDIUM DIFFICILE; GENE EXPRESSION REGULATION, BACTERIAL; GENES, BACTERIAL; GENOMICS; HUMANS; MICROBIAL SENSITIVITY TESTS; MULTIGENE FAMILY; OPERON; PHYLOGENY; URIDINE DIPHOSPHATE N-ACETYLMURAMIC ACID; VANCOMYCIN; VANCOMYCIN RESISTANCE;

CLOSTRIDIUM DIFFICILE;

EID: 84879822520     PISSN: 13500872     EISSN: 14652080     Source Type: Journal    
DOI: 10.1099/mic.0.065060-0     Document Type: Article

References (38)

1. Ammam, F., Marvaud, J. C. & Lambert, T. (2012). Distribution of the vanG-like gene cluster in Clostridium difficile clinical isolates. Can J Microbiol 58, 547-551.
2. Arthur, M., Depardieu, F., Reynolds, P. & Courvalin, P. (1996a). Quantitative analysis of the metabolism of soluble cytoplasmic peptidoglycan precursors of glycopeptide-resistant enterococci. Mol Microbiol 21, 33-44.
3. Arthur, M., Reynolds, P. & Courvalin, P. (1996b). Glycopeptide resistance in enterococci. Trends Microbiol 4, 401-407.
4. Berkner, S. & Lipps, G. (2007). An active nonautonomous mobile element in Sulfolobus islandicus REN1H1. J Bacteriol 189, 2145-2149.
5. Billot-Klein, D., Gutmann, L., Sablé, S., Guittet, E. & van Heijenoort, J. (1994). Modification of peptidoglycan precursors is a common feature of the low-level vancomycin-resistant VANB-type Enterococcus D366 and of the naturally glycopeptide-resistant species Lactobacillus casei, Pediococcus pentosaceus, Leuconostoc mesenteroides, and Enterococcus gallinarum. J Bacteriol 176, 2398-2405.
6. Bonnet, R., Cavallo, J. D., Chardon, H. &other authors (2013). Comité de l'antibiogramme de la Société Française de Microbiologie. Recommandations 2013. Société Française de Microbiologie.
7. Boyd, D. A., Du, T., Hizon, R., Kaplen, B., Murphy, T., Tyler, S., Brown, S., Jamieson, F., Weiss, K. & Mulvey, M. R. (2006). VanG-type vancomycin-resistant Enterococcus faecalis strains isolated in Canada. Antimicrob Agents Chemother 50, 2217-2221.
8. Boyd, D. A., Willey, B. M., Fawcett, D., Gillani, N. & Mulvey, M. R. (2008). Molecular characterization of Enterococcus faecalis N06-0364 with low-level vancomycin resistance harboring a novel D-Ala-D-Ser gene cluster, vanL. Antimicrob Agents Chemother 52, 2667-2672.
9. Courvalin, P. (2006). Vancomycin resistance in gram-positive cocci. Clin Infect Dis 42 (Suppl 1), S25-S34.
10. David, V., Bozdogan, B., Mainardi, J. L., Legrand, R., Gutmann, L. & Leclercq, R. (2004). Mechanism of intrinsic resistance to vancomycin in Clostridium innocuum NCIB 10674. J Bacteriol 186, 3415-3422.
11. Depardieu, F., Bonora, M. G., Reynolds, P. E. & Courvalin, P. (2003). The vanG glycopeptide resistance operon from Enterococcus faecalis revisited. Mol Microbiol 50, 931-948.
12. Gay, N. J., Tybulewicz, V. L. & Walker, J. E. (1986). Insertion of transposon Tn7 into the Escherichia coli glmS transcriptional terminator. Biochem J 234, 111-117.
13. Gerding, D. N., Muto, C. A. & Owens, R. C., Jr (2008). Treatment of Clostridium difficile infection. Clin Infect Dis 46 (Suppl 1), S32-S42.
14. Heap, J. T., Pennington, O. J., Cartman, S. T., Carter, G. P. & Minton, N. P. (2007). The ClosTron: a universal gene knock-out system for the genus Clostridium. J Microbiol Methods 70, 452-464.
15. Hussain, H. A., Roberts, A. P. & Mullany, P. (2005). Generation of an erythromycin-sensitive derivative of Clostridium difficile strain 630 (630Derm) and demonstration that the conjugative transposon Tn916DE enters the genome of this strain at multiple sites. J Med Microbiol 54, 137-141.
16. Kelly, C. P. & LaMont, J. T. (1998). Clostridium difficile infection. Annu Rev Med 49, 375-390.
17. Lavollay, M., Arthur, M., Fourgeaud, M., Dubost, L., Marie, A., Riegel, P., Gutmann, L. & Mainardi, J. L. (2009). The b-lactam-sensitive D,Dcarboxypeptidase activity of Pbp4 controls the L,D and D,D transpeptidation pathways in Corynebacterium jeikeium. Mol Microbiol 74, 650-661.
18. Lebreton, F., Depardieu, F., Bourdon, N., Fines-Guyon, M., Berger, P., Camiade, S., Leclercq, R., Courvalin, P. & Cattoir, V. (2011). D-Ala-D-Ser VanN-type transferable vancomycin resistance in Enterococcus faecium. Antimicrob Agents Chemother 55, 4606-4612.
19. Leclercq, R., Derlot, E., Duval, J. & Courvalin, P. (1988). Plasmidmediated resistance to vancomycin and teicoplanin in Enterococcus faecium. N Engl J Med 319, 157-161.
20. Lemée, L. & Pons, J. L. (2010). Multilocus sequence typing for Clostridium difficile. Methods Mol Biol 646, 77-90.
21. Lemee, L., Dhalluin, A., Pestel-Caron, M., Lemeland, J. F. & Pons, J. L. (2004). Multilocus sequence typing analysis of human and animal Clostridium difficile isolates of various toxigenic types. J Clin Microbiol 42, 2609-2617.
22. Mahillon, J., Léonard, C. & Chandler, M. (1999). IS elements as constituents of bacterial genomes. Res Microbiol 150, 675-687.
23. Mainardi, J. L., Villet, R., Bugg, T. D., Mayer, C. & Arthur, M. (2008). Evolution of peptidoglycan biosynthesis under the selective pressure of antibiotics in Gram-positive bacteria. FEMS Microbiol Rev 32, 386-408.
24. McKessar, S. J., Berry, A. M., Bell, J. M., Turnidge, J. D. & Paton, J. C. (2000). Genetic characterization of vanG, a novel vancomycin resistance locus of Enterococcus faecalis. Antimicrob Agents Chemother 44, 3224-3228.
25. Meziane-Cherif, D., Saul, F. A., Haouz, A. & Courvalin, P. (2012). Structural and functional characterization of VanG D-Ala: D-Ser ligase associated with vancomycin resistance in Enterococcus faecalis. J Biol Chem 287, 37583-37592.
26. Patel, R., Piper, K., Cockerill, F. R., III, Steckelberg, J. M. & Yousten, A. A. (2000). The biopesticide Paenibacillus popilliae has a vancomycin resistance gene cluster homologous to the enterococcal VanA vancomycin resistance gene cluster. Antimicrob Agents Chemother 44, 705-709.
27. Peltier, J., Courtin, P., El Meouche, I., Lemée, L., Chapot-Chartier, M. P. & Pons, J. L. (2011). Clostridium difficile has an original peptidoglycan structure with a high level of N-acetylglucosamine deacetylation and mainly 3-3 cross-links. J Biol Chem 286, 29053-29062.
28. Peters, J. E. & Craig, N. L. (2001). Tn7: smarter than we thought. Nat Rev Mol Cell Biol 2, 806-814.
29. Rupnik, M., Avesani, V., Janc, M., von Eichel-Streiber, C. & Delmée, M. (1998). A novel toxinotyping scheme and correlation of toxinotypes with serogroups of Clostridium difficile isolates. J Clin Microbiol 36, 2240-2247.
30. Sacco, E., Hugonnet, J. E., Josseaume, N., Cremniter, J., Dubost, L., Marie, A., Patin, D., Blanot, D., Rice, L. B. & other authors (2010). Activation of the L,D-transpeptidation peptidoglycan cross-linking pathway by a metallo-D,D-carboxypeptidase in Enterococcus faecium. Mol Microbiol 75, 874-885.
31. Sebaihia, M., Wren, B. W., Mullany, P., Fairweather, N. F., Minton, N., Stabler, R., Thomson, N. R., Roberts, A. P., Cerdeño-Tárraga, A. M. & other authors (2006). The multidrug-resistant human pathogen Clostridium difficile has a highly mobile, mosaic genome. Nat Genet 38, 779-786.
32. Severin, A., Tabei, K., Tenover, F., Chung, M., Clarke, N. & Tomasz, A. (2004). High level oxacillin and vancomycin resistance and altered cell wall composition in Staphylococcus aureus carrying the staphylococcal mecA and the enterococcal vanA gene complex. J Biol Chem 279, 3398-3407.
33. Tschudin-Sutter, S., Widmer, A. F. & Perl, T. M. (2012). Clostridium difficile: novel insights on an incessantly challenging disease. Curr Opin Infect Dis 25, 405-411.
34. Vedantam, G., Novicki, T. J. & Hecht, D. W. (1999). Bacteroides fragilis transfer factor Tn5520: the smallest bacterial mobilizable transposon containing single integrase and mobilization genes that function in Escherichia coli. J Bacteriol 181, 2564-2571.
35. Viswanathan, V. K., Mallozzi, M. J. & Vedantam, G. (2010). Clostridium difficile infection: an overview of the disease and its pathogenesis, epidemiology and interventions. Gut Microbes 1, 234-242.
36. Warny, M., Pepin, J., Fang, A., Killgore, G., Thompson, A., Brazier, J., Frost, E. & McDonald, L. C. (2005). Toxin production by an emerging strain of Clostridium difficile associated with outbreaks of severe disease in North America and Europe. Lancet 366, 1079-1084.
37. Xu, X., Lin, D., Yan, G., Ye, X., Wu, S., Guo, Y., Zhu, D., Hu, F., Zhang, Y. & other authors (2010). vanM, a new glycopeptide resistance gene cluster found in Enterococcus faecium. Antimicrob Agents Chemother 54, 4643-4647.
38. Zar, F. A., Bakkanagari, S. R., Moorthi, K. M. & Davis, M. B. (2007). A comparison of vancomycin and metronidazole for the treatment of Clostridium difficile-associated diarrhea, stratified by disease severity. Clin Infect Dis 45, 302-307. Edited by: A. O'Neill