Bacterial lipid modification enhances immunoprophylaxis of filarial abundant larval transcript-2 protein in Mastomys model

Parasite Immunology

Volumn 35, Issue 7-8, 2013, Pages 201-213

  Sharmila, S ^a   Christiana, I ^a   Kiran, P ^b   Reddy, M V R ^b   Sankaran, K ^a   Kaliraj, P ^a  

^a ANNA UNIVERSITY   (India)

^b MAHATMA GANDHI INSTITUTE OF MEDICAL SCIENCES   (India)

Author keywords

Abundant larval transcript; Bacterial lipid modification; Brugia malayi; Immunoprophylaxis; Lymphatic filariasis; Mastomys

Indexed keywords

ABUNDANT LARVAL TRANSCRIPT 2 PROTEIN; GAMMA INTERFERON; LIPID; PROTOZOAL VACCINE; RECOMBINANT PROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIBODY TITER; ARTICLE; BRUGIA MALAYI; BRUGIAN FILARIASIS; CELLULAR DISTRIBUTION; CONTROLLED STUDY; IMMUNE RESPONSE; IMMUNOPROPHYLAXIS; LARVA; MALE; MASTOMYS; NONHUMAN; PRIORITY JOURNAL; PROTEIN ENGINEERING; PROTEIN EXPRESSION; PROTEIN MODIFICATION; PROTEIN PURIFICATION; TH1 TH2 BALANCE; VACCINATION;

ABUNDANT LARVAL TRANSCRIPT; BACTERIAL LIPID MODIFICATION; BRUGIA MALAYI; IMMUNOPROPHYLAXIS; LYMPHATIC FILARIASIS; MASTOMYS;

ANIMALS; ANTIBODIES, HELMINTH; ANTIGENS, HELMINTH; BRUGIA MALAYI; CYTOKINES; ELEPHANTIASIS, FILARIAL; EPITOPES, T-LYMPHOCYTE; ESCHERICHIA COLI; GLYCERIDES; HUMANS; IMMUNIZATION; LARVA; LIPIDS; LYMPHOCYTE ACTIVATION; MALE; MURINAE; PROTEIN ENGINEERING; RECOMBINANT PROTEINS; T-LYMPHOCYTES; VACCINES;

BACTERIA (MICROORGANISMS); BRUGIA MALAYI; MASTOMYS; MASTOMYS COUCHA;

EID: 84879806732     PISSN: 01419838     EISSN: 13653024     Source Type: Journal    
DOI: 10.1111/pim.12034     Document Type: Article

References (50)

1. Chu BK, Hooper PJ, Bradley MH, McFarland DA & Ottesen EA. The economic benefits resulting from the first 8 years of the Global Programme to Eliminate Lymphatic Filariasis (2000-2007). PLoS Negl Trop Dis 2010; 4: e708. doi: 10.1371/journal.pntd.0000708.
2. Schwab AE, Boakye DA, Kyelem D & Prichard RK. Detection of benzimidazole resistance-associated mutations in the filarial nematode Wuchereria bancrofti and evidence for selection by albendazole and ivermectin combination treatment. Am J Trop Med Hyg 2005; 73: 234-238.
3. Mitja O, Paru R, Hays R, et al. The impact of a filariasis control program on Lihir Island, Papua New Guinea. PLoS Negl Trop Dis 2011; 5: e1286. doi: 10.1371/journal.pntd.0001286.
4. Taylor MJ, Hoerauf A & Bockarie M. Lymphatic filariasis and Onchocerciasis. Lancet 2010; 376: 1175-1185.
5. Bergquist R & Lustigman S. Control of important helminthic infections vaccine development as part of the solution. Adv Parasitol 2010; 73: 297-326.
6. Ghedin E, Wang S, Spiro D, et al. Draft genome of the filarial nematode parasite Brugia malayi. Science 2007; 317: 1756-1760.
7. Gregory WF, Atmadja AK, Allen JE & Maizels RM. The abundant larval transcript 1/2 genes of Brugia malayi encode stage-specific candidate vaccine antigens for filariasis. Infect Immun 2000; 68: 4174-4179.
8. Gnanasekar M, Rao KV, He YX, et al. Novel phage display-based subtractive screening to identify vaccine candidates of Brugia malayi. Infect Immun 2004; 72: 4707-4715.
9. Sharmila S, Christiana I, Kiran P, Reddy MVR & Kaliraj P. The adjuvant-free immunoprotection of recombinant filarial protein abundant larval transcript-2 (ALT-2) in Mastomys coucha and the immunoprophylactic importance of its putative signal sequence. Exp Parasitol 2011; 129: 247-253.
10. Hernández I, Sanmartín O, Cardá C, Gómez S & Alfaro A. B-cell pseudolymphoma caused by aluminium hydroxide following hyposensitization therapy. Actas Dermo-Sifiliográficas 2008; 99: 213-216. (English Edition)
11. Cote-Sierra J, Bredan A, Toldos CM, et al. Bacterial lipoprotein-based vaccines induce tumor necrosis factor-dependent Type 1 protective immunity against Leishmania major. Infect Immun 2002; 70: 240-248.
12. Chen H, Liu S, Liu H, et al. A novel technology for the production of a heterologous lipoprotein immunogen in high yield has implications for the field of vaccine design. Vaccine 2009; 27: 1400-1409.
13. Weis JJ, Ma Y & Erdile LF. Biological activities of native and recombinant Borrelia burgdorferi outer surface protein A: dependence on lipid modification. Infect Immun 1994; 62: 4632-4636.
14. Neff L, Daher S, Muzzin P, et al. Molecular characterization and subcellular localization of macrophage infectivity potentiator, a Chlamydia trachomatis lipoprotein. J Bacteriol 2007; 189: 4739-4748.
15. Hsu CA, Lin WR, Li JC, et al. Immunoproteomic identification of the hypothetical protein NMB1468 as a novel lipoprotein ubiquitous in Neisseria meningitidis with vaccine potential. Proteomics 2008; 8: 2115-2125.
16. Kamalakkannan S, Murugan V, Jagannadham MV, Nagaraj R & Sankaran K. Bacterial lipid modification of proteins for novel protein engineering applications. Protein Eng Des Sel 2004; 17: 721-729.
17. Babu MM & Sankaran K. DOLOP - database of bacterial lipoproteins. Bioinformatics 2002; 18: 641-643.
18. Brombacher E, Baratto A, Dorel C & Landini P. Gene expression regulation by the curli activator CsgD protein: modulation of cellulose biosynthesis and control of negative determinants for microbial adhesion. J Bacteriol 2006; 188: 2027-2037.
19. Retamal CA, Thiebaut P & Alves EW. Protein purification from polyacrylamide gels by sonication extraction. Anal Biochem 1999; 268: 15-20.
20. Hayashi S & Wu HC. Lipoproteins in bacteria. J Bioenerg Biomembr 1990; 22: 451-471.
21. Shruthi H, Anand P, Murugan V & Sankaran K. Twin arginine translocase pathway and fast-folding lipoprotein biosynthesis in E. coli: interesting implications and applications. Mol BioSyst 2010; 6: 1-9.
22. Hoenig V & Werner F. Is propylene glycol an inert substance? Toxicol Lett 1980; 5: 389-392.
23. Rathaura S, Yadava M, Gupta S, Anandharaman V & Reddy MV. Filarial glutathione-S-transferase: a potential vaccine candidate against lymphatic filariasis. Vaccine 2008; 26: 4094-4100.
24. Suzuki T & Seregeg IG. A mass dissection technique for determining infectivity rate of filariasis vectors. Jpn J Exp Med 1979; 49: 117-121.
25. de Paula L, Silva CL, Carlos D, et al. Comparison of different delivery systems of DNA vaccination for the induction of protection against tuberculosis in mice and guinea pigs. Genet Vaccines Ther 2007; 5: 2. doi: 10.1186/1479-0556-5-2.
26. Fleer A & Krediet TG. Innate immunity: toll-like receptors and some more. A brief history, basic organization and relevance for the human newborn. Neonatology 2007; 92: 145-157.
27. Iwasaki A & Medzhitov R. Toll-like receptor control of the adaptive immune responses. Nat Immunol 2004; 5: 987-995.
28. Aliprantis AO, Yang R, Mark MR, et al. Cell activation and apoptosis by bacterial lipoproteins through toll-like receptor-2. Science 1999; 285: 736-738.
29. Jin MS, Kim SE, Heo JY, et al. Crystal structure of the TLR1-TLR2 heterodimer induced by binding of a tri-acylated lipopeptide. Cell 2007; 130: 979-981.
30. Zeng W, Ghosh S, Lau YF, Brown LE & Jackson DC. Highly immunogenic and totally self-adjuvanting synthetic lipopeptides as immunocontraceptive vaccines. J Immunol 2002; 169: 4905-4912.
31. Ying X, Chen X, Wang Y, Fang W & Luo D. Signal sequence analysis of protein sequences from the filarial nematode parasite Brugia malayi and the evolution of secreted proteins in parasites. Parasitol Res 2009; 104: 1321-1326.
32. Lawrence RA. Immunity to filarial nematodes. Vet Parasitol 2001; 100: 33-44.
33. Gray CA & Lawrence RA. A role for antibody and Fc receptor in the clearance of Brugia malayi microfilariae. Eur J Immunol 2002; 32: 1114-1120.
34. Madhumathi J, Prince PR, Anugraha G, et al. Identification and characterization of nematode specific protective epitopes of Brugia malayi TRX towards development of synthetic vaccine construct for lymphatic filariasis. Vaccine 2010; 28: 5038-5048.
35. Tyagi K, Murthy PK & Chatterjee RK. Brugia malayi in Mastomys coucha: establishment in immunosuppressed animals. Acta Trop 1998; 70: 157-162.
36. Piessens WF, Wadee AA & Kurniawan L. Regulation of immune responses in lymphatic filariasis. Ciba Found Symp 1987; 127: 164-179.
37. Sher A, Pearce E & Kaye P. Shaping the immune response to parasites: role of dendritic cells. Curr Opin Immunol 2003; 15: 421-429.
38. Coffman RL, Seymour BWP, Lebman DA, Hiraki DD & Christiansen JA. The role of helper T cell products in mouse B cell differentiation and isotype regulation. Immunol Rev 1988; 10: 5-28.
39. Robinson JH, Case MC & Brooks CG. Palmitic acid conjugation of a protein antigen enhances major histocompatibility complex class II-restricted presentation to T cells. Immunology 1992; 76: 593-598.
40. Hoek KL, Antony P, Lowe J, Shinners N & Sarmah B. Transitional B cell fate is associated with developmental stage-specific regulation of diacylglycerol and calcium signaling upon B cell receptor engagement. J Immunol 2006; 177: 5405-5413.
41. Kronin V, Winkel K, Süss G, Kelso A & Heath W. A subclass of dendritic cells regulates the response of naive CD8 T cells by limiting their IL-2 production. J Immunol 1996; 157: 3819-3827.
42. Banyer JL, Halliday DCT, Thomson SA & Hamilton NHR. Combinations of IFN-γ and IL-4 induce distinct profiles. Genes Immun 2003; 4: 427-440.
43. Nutman TB & Kumaraswami V. Regulation of the immune response in lymphatic filariasis: perspectives on acute and chronic infection with Wuchereria bancrofti in South India. Parasite Immunol 2001; 23: 389-399.
44. Babu S, Blauvelt CP, Kumaraswami V & Nutman TB. Diminished expression and function of TLR in lymphatic filariasis: a novel mechanism of immune dysregulation. J Immunol 2005; 175: 1170-1176.
45. Volkmann L, Saeftel M, Bain O, Fischer K, Fleischer B & Hoerauf A. Interleukin-4 is essential for the control of microfilariae in murine infection with the filaria Litomosoides sigmodontis. Infect Immun 2001; 69: 2950-2956.
46. Martin C, Al-Qaoud KM, Ungeheuer MN, et al. IL-5 is essential for vaccine-induced protection and for resolution of primary infection in murine filariasis. Med Microbiol Immunol 2000; 189: 67-74.
47. Thirugnanam S, Pandiaraja P, Ramaswamy K, et al. Brugia malayi: comparison of protective immune responses induced by Bm-alt-2 DNA, recombinant Bm-ALT-2 protein and prime-boost vaccine regimens in a jird model. Exp Parasitol 2007; 116: 483-491.
48. Madhumathi J, Prince PR, Rao DN & Kaliraj P. Dominant T cell epitopes of filarial Bm ALT-2 and their cytokine profile in Balb/c mice. Parasite Immunol 2010; 32: 760-763.
49. Liu T, König R, Sha J, et al. Immunological responses against Salmonella enterica serovar Typhimurium Braun lipoprotein and lipid A mutant strains in Swiss-Webster mice: potential use as live-attenuated vaccines. Microb Pathog 2008; 44: 224-237.
50. Infante-Duarte C & Kamradt T. Lipopeptides of Borrelia burgdorferi outer surface proteins induce Th1 phenotype development in αβ T-cell receptor transgenic mice. Infect Immun 1997; 65: 4094-4099.