Control of Important Helminthic Infections. VaccineDevelopment as Part of the Solution

Advances in Parasitology

Volumn 73, Issue C, 2010, Pages 297-326

  Bergquist, Robert ^a   Lustigman, Sara ^b  

^a Brastad   (Sweden)

^b NEW YORK BLOOD CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

1 [2 [3 (2 CHLOROETHYL) 3 NITROSOUREIDO] 1 METHYLTHIOETHYL] 5 FLUOROURACIL; ALUMINUM POTASSIUM SULFATE; BENZIMIDAZOLE; DNA VACCINE; EG 95; GAMMA INTERFERON; IMMUNOLOGICAL ADJUVANT; INTERLEUKIN 1; IVERMECTIN; LIPOPEPTIDE; LIPOPOLYSACCHARIDE; PARASITE ANTIGEN; PEPTIDE VACCINE; PHOSPHORYL LIPID A; RECOMBINANT VACCINE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; VACCINE;

ANTIBODY RESPONSE; BOOK; CESTODIASIS; DRUG DESIGN; DRUG MANUFACTURE; ECHINOCOCCOSIS; ECHINOCOCCUS GRANULOSUS; HOST PARASITE INTERACTION; HUMAN; IMMUNOGENICITY; LYMPHATIC FILARIASIS; NEMATODIASIS; ONCHOCERCIASIS; PARASITE CONTROL; PARASITE TRANSMISSION; PRIORITY JOURNAL; TAENIA SOLIUM; TREMATODIASIS; VACCINE PRODUCTION; ANIMAL; CESTODE; HELMINTHIASIS; HELMINTHIASIS, ANIMAL; IMMUNOLOGY; NEMATODE; TREMATODE;

ANIMALS; CESTODA; HELMINTHIASIS; HELMINTHIASIS, ANIMAL; HUMANS; NEMATODA; TREMATODA; VACCINES;

EID: 77954605078     PISSN: 0065308X     EISSN: None     Source Type: Book Series    
DOI: 10.1016/S0065-308X(10)73010-4     Document Type: Chapter

References (130)

1. Abubucker S., Martin J., Yin Y., Fulton L., Yang S.P., Hallsworth-Pepin K., et al. The canine hookworm genome: analysis and classification of Ancylostoma caninum survey sequences. Mol. Biochem. Parasitol. 2008, 157:187-192.
2. Achukwi M.D., Harnett W., Enyong P., Renz A. Successful vaccination against Onchocerca ochengi infestation in cattle using live Onchocerca volvulus infective larvae. Parasite Immunol. 2007, 29:113-116.
3. Acosta L.P., Waine G., Aligui G.D., Tiu W.U., Olveda R.M. Immune correlate study on human Schistosoma japonicum in a well-defined population in Leyte Philippines: II. Cellular immune responses to S. japonicum recombinant and native antigens. Acta Trop. 2002, 84:137-149.
4. Ahmad G., Zhang W., Torben W., Haskins C., Diggs C., Noor Z., Le L., et al. Prime-boost and recombinant protein vaccination strategies using Sm-p80 protects against Schistosoma mansoni infection in the mouse model to levels previously attainable only by the irradiated cercarial vaccine. Parasitol. Res. 2009, 105:1767-1777.
5. Allen J.E., Adjei O., Bain O., Hoerauf A., Hoffmann W.H., Makepeace B.L., et al. Of mice, cattle, and humans: the immunology and treatment of river blindness. PLoS Negl. Trop. Dis. 2008, 2:e217.
6. Almeida C.R., Stoco P.H., Wagner G., Sincero T.C., Rotava G., Bayer-Santos E., et al. Transcriptome analysis of Taenia solium cysticerci using Open Reading Frame ESTs (ORESTES). Parasit. Vectors 2009, 2:35.
7. Al-Sherbiny M., Osman A., Barakat R., El Morshedy H., Bergquist R., Olds R. In vitro cellular and humoral responses to Schistosoma mansoni vaccine candidate antigens. Acta Trop. 2003, 88:117-130.
8. Amri M., Mezioug D., Touil-Boukoffa C. Involvement of IL-10 and IL-4 in evasion strategies of Echinococcus granulosus to host immune response. Eur. Cytokine Netw. 2009, 20:63-68.
9. Argiro L., Henri S., Dessein H., Kouriba B., Dessein A.J., Bourgois A. Induction of a protection against S. mansoni with a MAP containing epitopes of Sm37-GAPDH and Sm10-DLC. Effect of coadsorption with GM-CSF on alum. Vaccine 2000, 18:2033-2038.
10. Attwood S.W., Fatih F.A., Upatham E.S. DNA-sequence variation among Schistosoma mekongi populations and related taxa; phylogeography and the current distribution of Asian schistosomiasis. PLoS Negl. Trop. Dis. 2008, 2:e200.
11. Bennuru S., Semnani R., Meng Z., Ribeiro J.M., Veenstra T.D., Nutman T.B. Brugia malayi excreted/secreted proteins at the host/parasite interface: stage- and gender-specific proteomic profiling. PLoS Negl. Trop. Dis. 2009, 3:e410.
12. Bergquist N.R., Colley D.G. Schistosomiasis vaccine: research to development. Parasitol. Today 1998, 14:99-104.
13. Bergquist R., Utzinger J., McManus D.P. Trick or treat: the role of vaccines in integrated schistosomiasis control. PLoS Negl. Trop. Dis. 2008, 2:e244.
14. Berriman M., Haas B.J., LoVerde P.T., Wilson R.A., Dillon G.P., Cerqueira G.C., et al. The genome of the blood fluke Schistosoma mansoni. Nature 2009, 460:352-358.
15. Bethony J.M., Simon G., Diemert D.J., Bethony J.M., Simon G., Diemer D.J., et al. Randomized, placebo-controlled, double-blind trial of the Na-ASP-2 hookworm vaccine in unexposed adults. Vaccine 2008, 26:2408-2417.
16. Borchert N., Becker-Pauly C., Wagner A., Fischer P., Stöcker W., Brattig N.W. Identification and characterization of onchoastacin, an astacin-like metalloproteinase from the filaria Onchocerca volvulus. Microbes Infect. 2007, 9:498-506.
17. Boussinesq M. Onchocerciasis control: biological research is still needed. Parasite 2008, 15:510-514.
18. Brindley P.J., Mitreva M., Ghedin E., Lustigman S. Helminth genomics: the implications for human health. PLoS Negl. Trop. Dis. 2009, 3:e538.
19. Burnette W.N. "Western blotting": electrophoretic transfer of proteins from sodium dodecyl sulfate - polyacrylamide gels to unmodified nitrocellulose and radiographic detection with antibody and radioiodinated protein A. Anal. Biochem. 1981, 112:195-203.
20. Butterworth A.E., Capron M., Cordingley J.S., Dalton P.R., Dunne D.W., Kariuki H.C., et al. Immunity after treatment of human schistosomiasis mansoni. II. Identification of resistant individuals, and analysis of their immune responses. Trans. R. Soc. Trop. Med. Hyg. 1985, 79:393-408.
21. Capron A. Schistosomiasis: forty years' war on the worm. Parasitol. Today 1998, 14:379-384.
22. Capron A., Riveau G., Capron M., Trottein F. Schistosomes: the road from host-parasite interactions to vaccines in clinical trials. Trends Parasitol. 2005, 21:143-149.
23. Chow C., Gauci C.G., Vural G., Jenkins D.J., Heath D.D., Rosenzvit M.C., et al. Echinococcus granulosus: variability of the host-protective EG95 vaccine antigen in G6 and G7 genotypic variants. Exp. Parasitol. 2008, 119:499-505.
24. Churcher T.S., Pion S.D., Osei-Atweneboana M.Y., Prichard R.K., Awadzi K., Boussinesq M., et al. Identifying sub-optimal responses to ivermectin in the treatment of River Blindness. Proc. Natl. Acad. Sci. U.S.A 2009, 106:16716-16721.
25. Colatrella B. The Mectizan Donation Program: 20years of successful collaboration - a retrospective. Ann. Trop. Med. Parasitol. 2008, 102(Suppl. 1):7-11.
26. Coles G.C., Rhodes A.C., Wolstenholme A.J. Rapid selection for ivermectin resistance in Haemonchus contortus. Vet. Parasitol. 2005, 129:345-347.
27. Cook J.A., Steel C., Ottesen E.A. Towards a vaccine for onchocerciasis. Trends Parasitol. 2001, 17:555-558.
28. Coupar B.E., Oke P.G., Andrew M.E. Insertion sites for recombinant vaccinia virus construction: effects on expression of a foreign protein. J. Gen. Virol. 2000, 81:431-439.
29. Craig P.S., McManus D.P., Lightowlers M.W., Chabalgoity J.A., Garcia H.H., Gavidia C.M., et al. Prevention and control of cystic echinococcosis. Lancet Infect. Dis. 2007, 7:385-394.
30. Da'dara A.A., Li Y.S., Xiong T., Zhou J., Williams G.M., McManus, et al. DNA-based vaccines protect against zoonotic schistosomiasis in water buffalo. Vaccine 2008, 26:3617-3625.
31. Dang Z., Watanabe J., Kajino K., Oku Y., Matsumoto J., Yagi K., et al. Molecular cloning and characterization of a T24-like protein in Echinococcus multilocularis. Mol. Biochem. Parasitol. 2009, 168:117-119.
32. Dang Z., Yagi K., Oku Y., Kouguchi H., Kajino K., Watanabe J., et al. Evaluation of Echinococcus multilocularis tetraspanins as vaccine candidates against primary alveolar echinococcosis. Vaccine 2009, (Sep 25).
33. Dean D.A. Schistosoma and related genera: acquired resistance in mice. Exp. Parasitol. 1983, 55:1-104.
34. DeMarco R., Verjovski-Almeida S. Schistosomes - proteomics studies for potential novel vaccines and drug targets. Drug Discov. Today 2009, 14:472-478.
35. Diemert D.J., Bethony J.M., Hotez P.J. Hookworm vaccines. Clin. Infect. Dis. 2008, 46:282-288.
36. Duerr H.P., Hoffmann W.H., Eichner M. Does resistance to filarial reinfections become leaky over time?. Trends Parasitol. 2008, 24:350-354.
37. Egerton J.R., Suhayda D., Eary C.H. Laboratory selection of Haemonchus contortus for resistance to ivermectin. J. Parasitol. 1988, 74:614-617.
38. Erttmann K.D., Büttner D.W. Immunohistological studies on Onchocerca volvulus paramyosin. Parasitol. Res. 2009, 105:1371-1374.
39. Erttmann K.D., Kleensang A., Schneider E., Hammerschmidt S., Büttner D.W., Gallin M. Cloning, characterization and DNA immunization of an Onchocerca volvulus glyceraldehyde-3-phosphate dehydrogenase (Ov-GAPDH). Biochim. Biophys. Acta. 2005, 1741:85-94.
40. Ferru I., Georges B., Bossus M., Estaquier J., Delacre M., Harn D.A., et al. Analysis of the immune response elicited by a multiple antigen peptide (MAP) composed of two distinct protective antigens derived from the parasite Schistosoma mansoni. Parasit. Immunol. 1997, 19:1-11.
41. Fitzpatrick J.M., Peak E., Perally S., Chalmers I.W., Barrett J., Yoshino T.P., et al. Anti-schistosomal intervention targets identified by lifecycle transcriptomic analyses. PLoS Negl. Trop. Dis. 2009, 3:e543.
42. Gauci C., Heath D., Chow C., Lightowlers M.W. Hydatid disease: vaccinology and development of the EG95 recombinant vaccine. Expert. Rev. Vaccines 2005, 4:103-112.
43. Ghedin E., Wang S., Spiro D., Caler E., Zhao Q., Crabtree J., et al. Draft genome of the filarial nematode parasite Brugia malayi. Science 2007, 317:1756-1760.
44. Gottstein B., Hemphill A. Echinococcus multilocularis: the parasite-host interplay. Exp. Parasitol. 2008, 119:447-452.
45. Goudot-Crozel V., Caillol D., Djabali M., Dessein A.J. The major parasite surface antigen associated with human resistance to schistosomiasis is a 37-kD glyceraldehyde-3P-dehydrogenase. J. Exp. Med. 1989, 170:2065-2080.
46. Gray D.J., Williams G.M., Li Y., Chen H., Li R.S., Forsyth S.J., et al. A cluster-randomized bovine intervention trial against Schistosoma japonicum in the People's Republic of China: design and baseline results. Am. J. Trop. Med. Hyg. 2007, 77:866-874.
47. Grossmann C., Tenbusch M., Nchinda G., Temchura V., Nabi G., Stone G.W., et al. Enhancement of the priming efficacy of DNA vaccines encoding dendritic cell-targeted antigens by synergistic toll-like receptor ligands. BMC Immunol. 2009, 3:43.
48. Guo J., Li Y., Gray D., Ning A., Hu G., Chen H., et al. A drug-based intervention study on the importance of buffaloes for human Schistosoma japonicum infection around Poyang Lake, People's Republic of China. Am. J. Trop. Med. Hyg. 2006, 74:335-341.
49. Haag K.L., Gottstein B., Ayala F.J. The EG95 antigen of Echinococcus spp. contains positively selected amino acids, which may influence host specificity and vaccine efficacy. PLoS One 2009, 4:e5362.
50. Harn D.A., Gu W., Oligino L.D., Mitsuyama M., Gebremichael A., Richter D. A protective monoclonal antibody specifically recognizes and alters the catalytic activity of schistosome triose-phosphate isomerase. J. Immunol. 1992, 148:562-567.
51. Hauguel T.M., Hackett C.J. Rationally designed vaccine adjuvants: separating efficacy from toxicity. Front Biosci. 2008, 13:2806-2813.
52. Hotez P.J., Kamath A. Neglected tropical diseases in sub-Saharan Africa: review of their prevalence, distribution, and disease burden. PLoS Negl. Trop. Dis. 2009, 3:e412.
53. Hotez P.J., Bottazzi M.E., Franco-Paredes C., Ault S.K., Periago M.R. The neglected tropical diseases of Latin America and the Caribbean: a review of disease burden and distribution and a roadmap for control and elimination. PLoS Negl. Trop. Dis. 2008, 2:e300.
54. Hu W., Yan Q., Shen D.K., Liu F., Zhu Z.D., Song H.D., et al. Evolutionary and biomedical implications of a Schistosoma japonicum complementary DNA resource. Nat. Genet. 2003, 35:139-147.
55. Jiang Z.H., Koganty R.R. Synthetic vaccines: the role of adjuvants in immune targeting. Curr. Med. Chem. 2003, 10:1423-1439.
56. Johansen M.V., Bogh H.O., Nansen P., Christensen N.O. Schistosoma japonicum infection in the pig as a model for human schistosomiasis japonica. Acta Trop. 2000, 76:85-99.
57. Johnson K.S., Harrison G.B., Lightowlers M.W., O'Hoy K.L., Cougle W.G., Dempster R.P., et al. Vaccination against ovine cysticercosis using a defined recombinant antigen. Nature 1989, 338:585-587.
58. Keiser J., Utzinger J. Emerging foodborne trematodiasis. Emerg. Infect. Dis. 2005, 11:1507-1514.
59. Krithika K.N., Dabir P., Kulkarni S., Anandharaman V., Reddy M.V. Identification of 38kDa Brugia malayi microfilarial protease as a vaccine candidate for lymphatic filariasis. Indian J. Exp. Biol. 2005, 43:759-768.
60. Kwissa M., Kasturi S.P., Pulendran B. The science of adjuvants. Expert Rev. Vaccines 2007, 6:673-684.
61. Kyngdon C.T., Gauci C.G., Gonzalez A.E., Flisser A., Zoli A., Read A.J., et al. Antibody responses and epitope specificities to the Taenia solium cysticercosis vaccines TSOL18 and TSOL45-1A. Parasite Immunol. 2006, 28:191-199.
62. Lafuente E.M., Reche P.A. Prediction of MHC-peptide binding: a systematic and comprehensive overview. Curr. Pharm. Des. 2009, 15:3209-3220.
63. Lawrence R.A., Devaney E. Lymphatic filariasis: parallels between the immunology of infection in humans and mice. Parasite Immunol. 2001, 23:353-361.
64. Lightowlers M.W. Vaccines for prevention of cysticercosis. Acta Trop. 2003, 87:129-135.
65. Lightowlers M.W. Vaccination for the prevention of cysticercosis. Dev. Biol. (Basel) 2004, 119:361-368.
66. Lightowlers M.W. Cestode vaccines: origins, current status and future prospects. Parasitology 2006, 133(Suppl.):S27-S42.
67. Lightowlers M.W. Vaccines against cysticercosis and hydatidosis: foundations in taeniid cestode immunology. Parasitol. Int. 2006, 55:S39-S43.
68. Lightowlers M.W., Heath D.D. Immunity and vaccine control of Echinococcus granulosus infection in animal intermediate hosts. Parassitologia 2004, 46:27-31.
69. Lightowlers M.W., Colebrook A.L., Gauci C.G., Gauci S.M., Kyngdon C.T., Monkhouse J.L., et al. Vaccination against cestode parasites: anti-helminth vaccines that work and why. Vet. Parasitol. 2003, 115:83-123.
70. Lindblad E.B. Aluminium adjuvants - in retrospect and prospect. Vaccine 2004, 22:3658-3668.
71. Loukas A., Bethony J.M., Williamson A.L., Goud G.N., Mendez S., Zhan B., et al. Vaccination of dogs with a recombinant cysteine protease from the intestine of canine hookworms diminishes the fecundity and growth of worms. J. Infect. Dis. 2004, 189:1952-1961.
72. Loukas A., Bethony J.M., Mendez S., Fujiwara R.T., Goud G.N., Ranjit N., et al. Vaccination with recombinant aspartic hemoglobinase reduces parasite load and blood loss after hookworm infection in dogs. PLoS Med. 2005, 2:e295.
73. Luo X., Zheng Y., Hou J., Zhang S., Cai X. Protection against Asiatic Taenia solium induced by a recombinant 45W-4B protein. Clin. Vaccine Immunol. 2009, 16:230-232.
74. Lustigman S., Abraham D. Onchocerciasis. Vaccines for biodefense and emerging and neglected diseases 2009, 1379-1400. Academic Press Inc - Elsevier Science & Technology, (Chapter 67), London. A.D.T. Barrett, L.R. Stanberry (Eds.).
75. Lustigman S., McCarter J.P. Ivermectin resistance in Onchocerca volvulus: toward a genetic basis. PLoS Negl. Trop. Dis. 2007, 1:e76.
76. Lustigman S., James E.R., Tawe W., Abraham D. Towards a recombinant antigen vaccine against Onchocerca volvulus. Trends Parasitol. 2002, 18:135-141.
77. Lustigman S., MacDonald A.J., Abraham D. CD4+-dependent immunity to Onchocerca volvulus third-stage larvae in humans and the mouse vaccination model: common ground and distinctions. Int. J. Parasitol. 2003, 33:1161-1171.
78. MacDonald A.J., Tawe W., Leon O., Cao L., Liu J., Oksov Y., et al. Ov-ASP-1, the Onchocerca volvulus homologue of the activation associated secreted protein family is immunostimulatory and can induce protective anti-larval immunity. Parasite Immunol. 2004, 26:53-62.
79. Makepeace B.L., Jensen S.A., Laney S.J., Nfon C.K., Njongmeta L.M., Tanya V.N., et al. Immunisation with a multivalent, subunit vaccine reduces patent infection in a natural bovine model of onchocerciasis during intense field exposure. PLoS Negl. Trop. Dis. 2009, 3:e544.
80. McCarthy J.S., Wieseman M., Tropea J., Kaslow D., Abraham D., Lustigman S., et al. Onchocerca volvulus glycolytic enzyme fructose-1, 6-bisphosphate aldolase as a target for a protective immune response in humans. Infect. Immun. 2002, 70:851-858.
81. McManus D.P. Echinococcosis with particular reference to Southeast Asia. Adv. Parasitol. 2010, 72:267-304.
82. McManus D.P., Dalton J.P. Vaccines against the zoonotic trematodes Schistosoma japonicum, Fasciola hepatica and Fasciola gigantica. Parasitology 2006, 133(Suppl.):S43-S61.
83. McManus D.P., Loukas A. The current status of vaccines for schistosomiasis. Clin. Microbiol. Rev. 2008, 21:225-242.
84. McManus D.P., Li Y., Gray D.J., Ross A.G. Conquering 'snail fever': schistosomiasis and its control in China. Expert. Rev. Anti. Infect. Ther. 2009, 7:473-485.
85. Mulvenna J., Hamilton B., Nagaraj S.H., Smyth D., Loukas A., Gorman J.J. Proteomics analysis of the excretory/secretory component of the blood-feeding stage of the hookworm Ancylostoma caninum. Mol. Cell Proteomics 2009, 8:109-121.
86. Nagaraj S.H., Gasser R.B., Ranganathan S. Needles in the EST haystack: large-scale identification and analysis of excretory-secretory (ES) proteins in parasitic nematodes using Expressed Sequence Tags (ESTs). PLoS Negl. Trop. Dis. 2008, 2:e301.
87. Nutman T.B. Future directions for vaccine-related onchocerciasis research. Trends Parasitol. 2002, 18:237-239.
88. Olveda R.M., Daniel B.L., Ramirez B.D., Aligui G.D., Acosta L.P., Fevidal P., et al. Schistosomiasis japonica in the Philippines: the long-term impact of population-based chemotherapy on infection, transmission, and morbidity. J. Infect. Dis. 1996, 174:163-172.
89. Osei-Atweneboana M.Y., Eng J.K., Boakye D.A., Gyapong J.O., Prichard R.K. Prevalence and intensity of Onchocerca volvulus infection and efficacy of ivermectin in endemic communities in Ghana: a two-phase epidemiological study. Lancet 2007, 369:2021-2029.
90. Pearce E.J., James S.L., Hieny S., Lanar D.E., Sher A. Induction of protective immunity against Schistosoma mansoni by vaccination with schistosome paramyosin (Sm97), a nonsurface parasite antigen. Proc. Natl. Acad. Sci. U.S.A 1988, 85:5678-5682.
91. Persing D.H., Coler R.N., Lacy M.J., Johnson D.A., Baldridge J.R., et al. Taking toll: lipid A mimetics as adjuvant and immunomodulators. Trends Microbiol. 2002, 10(Suppl.):32-37.
92. Pichichero M.E. Improving vaccine delivery using novel adjuvant systems. Hum. Vaccin. 2008, 4:262-270.
93. Pokharel D.R., Rai R., Nandakumar Kodumudi K., Reddy M.V., Rathaur S. Vaccination with Setaria cervi 175kDa collagenase induces high level of protection against Brugia malayi infection in jirds. Vaccine 2006, 24:6208-6215.
94. Prieur E., Gilbert S.C., Schneider J., Moore A.C., Sheu E.G., Goonetilleke N., et al. A Plasmodium falciparum candidate vaccine based on a six-antigen polyprotein encoded by recombinant poxviruses. Proc. Natl. Acad. Sci. U.S.A 2004, 101:290-295.
95. Ramachandran S., Kumar M.P., Rami R.M., Chinnaiah H.B., Nutman T., Kaliraj P., et al. The larval specific lymphatic filarial ALT-2: induction of protection using protein or DNA vaccination. Microbiol. Immunol. 2004, 48:945-955.
96. Ramos C.R., Figueredo R.C., Pertinhez T.A., Vilar M.M., do Nascimento A.L., Tendler M., et al. Gene structure and M20T polymorphism of the Schistosoma mansoni Sm14 fatty acid-binding protein. Molecular, functioanl, and immunoprotection analysis. J. Biol. Chem. 2003, 278:12745-12751.
97. Ramos C.R., Spisni A., Oyama S., Sforça M.L., Ramos H.R., Vilar M.M., et al. Stability improvement of the fatty acid binding protein Sm14 from S. mansoni by Cys replacement: structural and functional characterization of a vaccine candidate. Biochim. Biophys. Acta 2009, 1794:655-662.
98. Reimert C.M., Tukahebwa E.M., Kabatereine Narcis B., David W., Dunne D.W., et al. Assessment of Schistosoma mansoni induced intestinal inflammation by means of eosinophil cationic protein, eosinophil protein X and myeloperoxidase before and after treatment with praziquantel. Acta Trop. 2008, 105:253-259.
99. Ribeiro de Jesus A., Araújo I., Bacellar O., Magalhães A., Pearce E., Harn D., et al. Human immune responses to Schistosoma mansoni vaccine candidate antigens. Infect. Immun. 2000, 68:2797-2803.
100. Rickard M.D., Harrison G.B., Heath D.D., Lightowlers M.W. Taenia ovis recombinant vaccine - 'quo vadit'. Parasitology 1995, 110(Suppl.):S5-S9.
101. Rosenzvit M.C., Camicia F., Kamenetzky L., Muzulin P.M., Gutierrez A.M. Identification and intra-specific variability analysis of secreted and membrane-bound proteins from Echinococcus granulosus. Parasitol. Int. 2006, 55(Suppl.):S63-S67.
102. Zhou Y., Zheng H., Liu F., Hu W., Wang Z.Q., Gang L., et al. The Schistosoma japonicum genome reveals features of host-parasite interplay. Nature 2009, 460:345-351. Schistosoma japonicum Genome Sequencing and Functional Analysis Consortium.
103. Schwab A.E., Boakye D.A., Kyelem D., Prichard R.K. Detection of benzimidazole resistance-associated mutations in the filarial nematode Wuchereria bancrofti and evidence for selection by albendazole and ivermectin combination treatment. Am. J. Trop. Med. Hyg. 2005, 73:234-238.
104. Sciutto E., Fragoso G., de Aluja A.S., Hernández M., Rosas G., Larralde C. Vaccines against cysticercosis. Curr. Top. Med. Chem. 2008, 8:415-423.
105. Siddiqui A.A., Pinkston J.R., Quinlin M.L., Kavikondala V., Rewers-Felkins K.A., Phillips T., et al. Characterization of protective immunity induced against Schistosoma mansoni via DNA priming with the large subunit of calpain (Sm-p80) in the presence of genetic adjuvants. Parasite 2005, 12:3-8.
106. Steeghs L., Tommassen J., Leusen J.H., van de Winkel J.G., van der Ley P. Teasing apart structural determinants of 'toxic' and 'adjuvanticy': implications for meningococcal vaccine development. J. Endotoxin Res. 2004, 10:113-119.
107. Steinmann P., Keiser J., Bos R., Tanner M., Utzinger J. Schistosomiasis and water resources development: systematic review, meta-analysis, and estimates of people at risk. Lancet Infect. Dis. 2006, 6:411-425.
108. Tchakouté V.L., Graham S.P., Jensen S.A., Makepeace B.L., Nfon C.K., Njongmeta L.M., et al. In a bovine model of onchocerciasis, protective immunity exists naturally, is absent in drug-cured hosts, and is induced by vaccination. Proc. Natl. Acad. Sci. U.S.A. 2006, 103:5971-5976.
109. Tendler M., Simpson A.J. The biotechnology-value chain: development of Sm14 as a schistosomiasis vaccine. Acta Trop. 2008, 108:263-266.
110. The Carter Center Schistosomiasis Control Program, Atlanta, USA. http://www.cartercenter.org/health/schistosomiasis/index.html.
111. Todd C.W., Colley D.G. Practical and ethical issues in the development of a vaccine against Schistosomiasis mansoni. Am. J. Trop. Med. Hyg. 2002, 66:348-358.
112. Torgerson P.R. Mathematical models for the control of cystic echinococcosis. Parasitol. Int. 2006, 55:S253-258.
113. Torgerson P.R. Dogs, vaccines and Echinococcus. Trends Parasitol. 2009, 25:57-58.
114. Vedi S., Dangi A., Hajela K., Misra-Bhattacharya S. Vaccination with 73kDa recombinant heavy chain myosin generates high level of protection against Brugia malayi challenge in jird and mastomys models. Vaccine 2008, 26:5997-6005.
115. Veerapathran A., Dakshinamoorthy G., Gnanasekar M., Reddy M.V., Kalyanasundaram R.E. Evaluation of Wuchereria bancrofti GST as a vaccine candidate for lymphatic filariasis. PLoS Negl. Trop. Dis. 2009, 3:e457.
116. Vilar M.M., Barrientos F., Almeida M., Thaumaturgo N., Simpson A., Garratt R., et al. An experimental bivalent peptide vaccine against schistosomiasis and fascioliasis. Vaccine 2003, 22:137-144.
117. Wang T.P., Vang Johansen M., Zhang S.Q., Wang F.F., Wu W.D., Zhang G.H., et al. Transmission of Schistosoma japonicum by humans and domestic animals in the Yangtze River valley, Anhui province, China. Acta Trop. 2005, 96:198-204.
118. Fact sheet N° 102 on lymphatic filariasis WHO. http://www.who.int/mediacentre/factsheets/fs102/en.
119. Prevention and control of schistosomiasis and soil-transmitted helminthiasis: report of a WHO expert committee. WHO Tech. Rep. Ser. 2002, 912:1-57. WHO.
120. African Programme for Onchocerciasis Control (APOC) WHO. http://www.who.int/apoc/onchocerciasis/en.
121. Preventive chemotherapy databank WHO. http://www.who.int/neglected_diseases/preventive_chemotherapy/databank/en/index.html.
122. Willingham III A.L., Wu H.-W., Conlan J., Satrija F. Combating Taenia solium Cysticercosis in Southeast Asia: an Opportunity for improving human health and livestock Production. Adv. Parasitol. 2010, 72:235-259.
123. Wu Y., Egerton G., Pappin D.J., Harrison R.A., Wilkinson M.C., Underwood A., et al. The Secreted Larval Acidic Proteins (SLAPs) of Onchocerca spp. are encoded by orthologues of the alt gene family of Brugia malayi and have host protective potential. Mol. Biochem. Parasitol. 2004, 134:213-224.
124. Xu M., Molento M., Blackhall W., Ribeiro P., Beech R., Prichard R. Ivermectin resistance in nematodes may be caused by alteration of P-glycoprotein homolog. Mol. Biochem. Parasitol. 1998, 91:327-335.
125. Zhan B., Liu S., Perally S., Xue J., Fujiwara R., Brophy P., et al. Biochemical characterization and vaccine potential of a heme-binding glutathione transferase from the adult hookworm Ancylostoma caninum. Infect. Immun. 2005, 73:6903-6911.
126. Zhang W., McManus D.P. Vaccination of dogs against Echinococcosus granulosus: a means to control hydatid disease?. Trends Parasitol. 2008, 24:419-424.
127. Zhang W., Ross A.G., McManus D.P. Mechanisms of immunity in hydatid disease: implications for vaccine development. J. Immunol. 2008, 181:6679-6685.
128. Zhou Z., Xia H., Hu X., Huang Y., Li Y., Li L., et al. Oral administration of a Bacillus subtilis spore-based vaccine expressing Clonorchis sinensis tegumental protein 22.3kDa confers protection against Clonorchis sinensis. Vaccine 2008, 26:1817-1825.
129. Zhu Y., Ren J., Da'dara A., Harn D., Xu M., Si J., et al. The protective effect of a Schistosoma japonicum Chinese strain 23kDa plasmid DNA vaccine in pigs is enhanced with IL-12. Vaccine 2004, 23:78-83.
130. Zhu Y., Si J., Harn D.A., Xu M., Ren J., Yu C., et al. Schistosoma japonicum triose-phosphate isomerase plasmid DNA vaccine protects pigs against challenge infection. Parasitology 2006, 132:67-71.