The adjuvant-free immunoprotection of recombinant filarial protein Abundant Larval Transcript-2 (ALT-2) in Mastomys coucha and the immunoprophylactic importance of its putative signal sequence

Experimental Parasitology

Volumn 129, Issue 3, 2011, Pages 247-253

  Sharmila, Sam ^a   Christiana, Immanuel ^a   Kiran, Pote ^b   Reddy, Maryada Venkata Rami ^b   Kaliraj, Perumal ^a  

^a ANNA UNIVERSITY   (India)

^b MAHATMA GANDHI INSTITUTE OF MEDICAL SCIENCES   (India)

Author keywords

Abundant Larval Transcript; Brugia malayi; Immunoprophylaxis; Lymphatic filariasis; Mastomys coucha; Worm clearance

Indexed keywords

ALUMINUM POTASSIUM SULFATE; GAMMA INTERFERON; IMMUNOGLOBULIN G ANTIBODY; IMMUNOGLOBULIN G1 ANTIBODY; IMMUNOGLOBULIN G2A ANTIBODY; IMMUNOGLOBULIN G2B ANTIBODY; IMMUNOGLOBULIN G3 ANTIBODY; INTERLEUKIN 10; INTERLEUKIN 2; INTERLEUKIN 4; INTERLEUKIN 5; NALT PROTEIN; PARASITE ANTIGEN; RECOMBINANT ABUNDANT LARVAL TRANSCRIPT 2 PROTEIN; SALT PROTEIN; UNCLASSIFIED DRUG;

ADJUVANT THERAPY; AMINO TERMINAL SEQUENCE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIBODY TITER; ARTICLE; BRUGIA MALAYI; BRUGIAN FILARIASIS; CELL PROLIFERATION; CELLULAR IMMUNITY; CONTROLLED STUDY; HUMORAL IMMUNITY; IMMUNOGLOBULIN BLOOD LEVEL; IMMUNOPROPHYLAXIS; MALE; MASTOMYS; MASTOMYS COUCHA; NONHUMAN; NUCLEOTIDE SEQUENCE; PARASITE CLEARANCE; PRIORITY JOURNAL; RECOMBINANT DNA TECHNOLOGY; SPLEEN CELL; TH1 TH2 BALANCE;

ANIMALS; ANTIBODIES, HELMINTH; ANTIGENS, HELMINTH; BRUGIA MALAYI; CYTOKINES; DISEASE MODELS, ANIMAL; FILARIASIS; GENE EXPRESSION; IMMUNITY, CELLULAR; IMMUNOGLOBULIN G; LYMPHOCYTE ACTIVATION; MALE; MURINAE; PROTEIN SORTING SIGNALS; RECOMBINANT PROTEINS; SPLEEN; VACCINES, SYNTHETIC;

ANIMALIA; BRUGIA MALAYI; MASTOMYS COUCHA;

EID: 80054738900     PISSN: 00144894     EISSN: 10902449     Source Type: Journal    
DOI: 10.1016/j.exppara.2011.08.005     Document Type: Article

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