Senescence-induced increases in intracellular oxidative stress and enhancement of the need for ascorbic acid in human fibroblasts

Molecular and Cellular Biochemistry

Volumn 380, Issue 1-2, 2013, Pages 129-141

  Saitoh, Yasukazu ^a   Morishita, Aiko ^a   Mito, Satomi ^a   Tsujiya, Tsubasa ^a   Miwa, Nobuhiko ^b  

^a PREFECTURAL UNIVERSITY OF HIROSHIMA   (Japan)

^b BUTSURYO COLLEGE OF OSAKA   (Japan)

Author keywords

Aging; Ascorbic acid; Intracellular oxidative stress; Senescent cell; Sodium dependent vitamin C transporter (SVCT)

Indexed keywords

ASCORBIC ACID; MESSENGER RNA; PEROXIDE; REACTIVE OXYGEN METABOLITE; SODIUM ASCORBIC ACID COTRANSPORTER; SUPEROXIDE;

ANTIOXIDANT ACTIVITY; ARTICLE; CELL AGING; CELL GROWTH; CELL LEVEL; CELL POPULATION; CELL SIZE; CELL STRESS; CONTROLLED STUDY; DRUG UPTAKE; EMBRYO; FIBROBLAST; GENE EXPRESSION; HUMAN; HUMAN CELL; OXIDATIVE STRESS; PROTEIN EXPRESSION; SENESCENCE;

ANTIOXIDANTS; ASCORBIC ACID; BLOTTING, WESTERN; CELL AGING; CELL LINE; FIBROBLASTS; GENE EXPRESSION; HUMANS; INTRACELLULAR SPACE; OXIDATIVE STRESS; PEROXIDES; REACTIVE OXYGEN SPECIES; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SODIUM-COUPLED VITAMIN C TRANSPORTERS; SUPEROXIDES; TIME FACTORS;

EID: 84879800098     PISSN: 03008177     EISSN: 15734919     Source Type: Journal    
DOI: 10.1007/s11010-013-1666-y     Document Type: Article

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