Electron currents generated by the human phagocyte NADPH oxidase

Nature

Volumn 392, Issue 6677, 1998, Pages 734-737

  Schrenzel, Jacques ^a,b   Serrander, Lena ^a   Bánfi, Botond ^a,c   Nüße, Oliver ^a   Fouyouzi, Reyhaneh ^a   Lew, Daniel P ^a   Demaurex, Nicolas ^d   Krause, Karl Heinz ^a  

^a GENEVA UNIVERSITY HOSPITALS   (Switzerland)

^b MAYO CLINIC   (United States)

^c SEMMELWEIS UNIVERSITY OF MEDICINE   (Hungary)

^d UNIVERSITY OF GENEVA MEDICAL SCHOOL   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; SUPEROXIDE;

ARTICLE; CELL MEMBRANE; CHRONIC GRANULOMATOUS DISEASE; CONTROLLED STUDY; ELECTRON TRANSPORT; EOSINOPHIL; HOST RESISTANCE; HUMAN; HUMAN CELL; PATCH CLAMP; PHAGOCYTE; PRIORITY JOURNAL;

ADULT; ELECTRON TRANSPORT; EOSINOPHILS; FEMALE; GLUCOSEPHOSPHATE DEHYDROGENASE DEFICIENCY; GRANULOMATOUS DISEASE, CHRONIC; HETEROZYGOTE; HUMANS; MALE; NADPH OXIDASE; OXYGEN; PATCH-CLAMP TECHNIQUES; PHAGOCYTES;

EUKARYOTA;

EID: 0032537190     PISSN: 00280836     EISSN: None     Source Type: Journal    
DOI: 10.1038/33725     Document Type: Article

References (24)

1. Mitchell, P. Foundations of vectorial metabolism and osmochemistry. Biosci. Rep. 11, 297-346 (1991).
2. Klebanoff, S. J. Oxygen metabolism and the toxic properties of phagocytes. Ann. Intern. Med. 93, 480-489 (1980).
3. Clark, R. A. The human neutrophil respiratory burst oxidase. J. Infect. Dis. 161, 1140-1147 (1990).
4. Segal, A. W. & Abo, A. The biochemical basis of the NADPH oxidase of phagocytes. Trends Biochem. Sci. 18, 43-47 (1993).
5. Chanock, S. J., el Benna, J., Smith, R. M. & Babior, B. M. The respiratory burst oxidase. J. Biol. Chem. 269, 24519-24522 (1994).
6. Clark, R. A. Genetic variation in chronic granulomatous disease. Hosp. Pract. 25, 51-55 (1990).
7. Boxer, L. A. & Blackwood, R. A. Leukocyte disorders: quantitative and qualitative disorders of the neutrophil, part 1. Pediatr. Rev. 17, 19-28 (1996).
8. + channel. Biochem. J. 246, 325-329 (1987).
9. Shult, P. A., Graziano, F. M., Wallow, I. H. & Busse, W. W. Comparison of Superoxide generation and luminol-dependent chemiluminescence with eosinophils and neutrophils from normal individuals. J. Lab. Clin. Med. 106, 638-645 (1985).
10. Gallin, E. K. & McKinney, L. C. in Current Topics in Membranes and Transport. Vol. 35: Mechanisms of Leukocyte Activation (eds Kleinzeller, A., Grinstein, S. & Rotstein, O. D.) 127-152 (Academic, San Diego, 1990).
11. Nanda, A. & Grinstein, S. The membrane potential of resting and activated neutrophils: determinants and significance. Cell Physiol. Biochem. 1, 65-75 (1991).
12. Demaurex, N., Schrenzel, J., Jaconi, M. E., Lew, D. P. & Krause, K.-H. Proton channels, plasma membrane potential, and respiratory burst in human neutrophils. Eur. J. Haematol. 51, 309-312 (1993).
13. Newburger, P.E. et al. Parental diagnosis of chronic granulomatous disease. N. Engl. J. Med. 300, 178-181 (1979).
14. Cross, A. R. & Jones, O. T. The effect of the inhibitor diphenylene iodonium on the superoxide-generating system of neutrophils. Specific labelling of a component polypeptide of the oxidase. Biochem. J. 237, 111-116 (1986).
15. Schrenzel, J., Lew, D. P. & Krause, K. H. Proton currents in human eosinophils. Am. J. Physiol. Cell Physiol 271, C1861-C1871 (1996).
16. Vives Corrons, J. L. et al. Severe-glucose-6-phosphate dehydrogenase (G6PD) deficiency associated with chronic hemolytic anemia, granulocyte dysfunction, and increased susceptibility to infections: description of a new molecular variant (G6PD Barcelona). Blood 59, 428-434 (1982).
17. Benesch, R. E. & Benesch, R. Enzymatic removal of oxygen for polarography and related methods. Science 118, 447-448 (1953).
18. Hille, B. Ionic Channels of Excitable Membranes (Sinauer Associates, Sunderland, MA, 1992).
19. Gordienko, D. V. et al. Voltage-activated proton current in eosinophils from human blood. J. Physiol. 496, 299-316 (1996).
20. Cherny, V. V., Markin, V. S. & De Coursey, T. E. The voltage-activated hydrogen ion conductance in a rat alveolar epithelial cells is determined by the pH gradient. J. Gen. Physiol. 105, 861-896 (1995).
21. Saier, M. H. Peter Mitchell and his chemiosmotic theories. ASM News 63, 13-21 (1997).
22. Zimmerli, W., Lew, D. P., Suter, S., Wyss, M. & Waldvogel, F. A. In vitro efficacy of several antibiotics against intracellular S. aureus in chronic granulomatous disease. Helv. Paediatr. Acta 38, 51-61 (1983).
23. + channels in HL-60 granulocytes. J. Physiol. (Lond.) 472, 373-390 (1993).
24. 2+ stores. J. Clin. Invest. 90, 830-839 (1992).