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Volumn 32, Issue 1, 2013, Pages 86-99

Baicalin maintains late-stage functional cardiomyocytes in embryoid bodies derived from murine embryonic stem cells

Author keywords

Baicalin; Cardiomyocytes; Differentiation; Embryonic stem cells

Indexed keywords

ALPHA ACTININ; BAICALIN; BIOLOGICAL MARKER; ATRIAL NATRIURETIC FACTOR; MYOSIN HEAVY CHAIN ALPHA; MYOSIN LIGHT CHAIN 2; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR GATA 4; TRANSCRIPTION FACTOR NK 2; TRANSCRIPTION FACTOR NKX2.5; TRANSCRIPTION FACTOR TBX5; UNCLASSIFIED DRUG;

EID: 84879765645     PISSN: 10158987     EISSN: 14219778     Source Type: Journal    
DOI: 10.1159/000350127     Document Type: Article
Times cited : (10)

References (54)
  • 5
    • 33646113360 scopus 로고    scopus 로고
    • Enhanced differentiation of human embryonic stem cells into cardiomyocytes by combining hanging drop culture and 5-azacytidine treatment
    • Yoon BS, Yoo SJ, Lee JE, You S, Lee HT, Yoon HS: Enhanced differentiation of human embryonic stem cells into cardiomyocytes by combining hanging drop culture and 5-azacytidine treatment. Differentiation 2006;74:149-159.
    • (2006) Differentiation , vol.74 , pp. 149-159
    • Yoon, B.S.1    Yoo, S.J.2    Lee, J.E.3    You, S.4    Lee, H.T.5    Yoon, H.S.6
  • 6
  • 7
    • 33847220393 scopus 로고    scopus 로고
    • Hepatocyte growth factor (HGF) enhances cardiac commitment of differentiating embryonic stem cells by activating PI3 kinase
    • Roggia C, Ukena C, Bohm M, Kilter H: Hepatocyte growth factor (HGF) enhances cardiac commitment of differentiating embryonic stem cells by activating PI3 kinase. Exp Cell Res 2007;313:921-930.
    • (2007) Exp Cell Res , vol.313 , pp. 921-930
    • Roggia, C.1    Ukena, C.2    Bohm, M.3    Kilter, H.4
  • 8
    • 0033794615 scopus 로고    scopus 로고
    • Antioxidant and free radical scavenging effects of baicalein, baicalin and wogonin
    • Shieh DE, Liu LT, Lin CC: Antioxidant and free radical scavenging effects of baicalein, baicalin and wogonin. Anticancer Res 2000;20:2861-2865.
    • (2000) Anticancer Res , vol.20 , pp. 2861-2865
    • Shieh, D.E.1    Liu, L.T.2    Lin, C.C.3
  • 9
    • 0034727789 scopus 로고    scopus 로고
    • Induction of apoptosis in prostate cancer cell lines by a flavonoid, baicalin
    • Chan FL, Choi HL, Chen ZY, Chan PS, Huang Y: Induction of apoptosis in prostate cancer cell lines by a flavonoid, baicalin. Cancer Lett 2000;160:219-228.
    • (2000) Cancer Lett , vol.160 , pp. 219-228
    • Chan, F.L.1    Choi, H.L.2    Chen, Z.Y.3    Chan, P.S.4    Huang, Y.5
  • 11
    • 79953300796 scopus 로고    scopus 로고
    • A novel therapeutic regimen for hepatic fibrosis using the combination of mesenchymal stem cells and baicalin
    • Qiao H, Tong Y, Han H, Xu W, Ren Z, Ouyang J, Chen Y: A novel therapeutic regimen for hepatic fibrosis using the combination of mesenchymal stem cells and baicalin. Pharmazie 2011;66:37-43.
    • (2011) Pharmazie , vol.66 , pp. 37-43
    • Qiao, H.1    Tong, Y.2    Han, H.3    Xu, W.4    Ren, Z.5    Ouyang, J.6    Chen, Y.7
  • 12
    • 34249079715 scopus 로고    scopus 로고
    • Differentiation of human umbilical cord blood mesenchymal stem cells toward neurons induced by baicalin in vitro
    • Yan XH, Huang RB: [Differentiation of human umbilical cord blood mesenchymal stem cells toward neurons induced by baicalin in vitro]. Zhonghua Er Ke Za Zhi 2006;44:214-219.
    • (2006) Zhonghua Er Ke Za Zhi , vol.44 , pp. 214-219
    • Yan, X.H.1    Huang, R.B.2
  • 13
    • 79551569169 scopus 로고    scopus 로고
    • Neuronal differentiation of C17.2 neural stem cells induced by a natural flavonoid, baicalin
    • Li M, Tsang KS, Choi ST, Li K, Shaw PC, Lau KF: Neuronal differentiation of C17.2 neural stem cells induced by a natural flavonoid, baicalin. Chembiochem 2011;12:449-456.
    • (2011) Chembiochem , vol.12 , pp. 449-456
    • Li, M.1    Tsang, K.S.2    Choi, S.T.3    Li, K.4    Shaw, P.C.5    Lau, K.F.6
  • 14
    • 0033573265 scopus 로고    scopus 로고
    • Effects of electrical fields on cardiomyocyte differentiation of embryonic stem cells
    • Sauer H, Rahimi G, Hescheler J, Wartenberg M: Effects of electrical fields on cardiomyocyte differentiation of embryonic stem cells. J Cell Biochem 1999;75:710-723.
    • (1999) J Cell Biochem , vol.75 , pp. 710-723
    • Sauer, H.1    Rahimi, G.2    Hescheler, J.3    Wartenberg, M.4
  • 17
    • 0036134448 scopus 로고    scopus 로고
    • Embryonic stem cells as a model to study cardiac, skeletal muscle, and vascular smooth muscle cell differentiation
    • Wobus AM, Guan K, Yang HT, Boheler KR: Embryonic stem cells as a model to study cardiac, skeletal muscle, and vascular smooth muscle cell differentiation. Methods Mol Biol 2002;185:127-156.
    • (2002) Methods Mol Biol , vol.185 , pp. 127-156
    • Wobus, A.M.1    Guan, K.2    Yang, H.T.3    Boheler, K.R.4
  • 20
    • 0033562350 scopus 로고    scopus 로고
    • Development and validation of real-time quantitative reverse transcriptase-polymerase chain reaction for monitoring gene expression in cardiac myocytes in vitro
    • Winer J, Jung CK, Shackel I, Williams PM: Development and validation of real-time quantitative reverse transcriptase-polymerase chain reaction for monitoring gene expression in cardiac myocytes in vitro. Anal Biochem 1999;270:41-49.
    • (1999) Anal Biochem , vol.270 , pp. 41-49
    • Winer, J.1    Jung, C.K.2    Shackel, I.3    Williams, P.M.4
  • 21
    • 62549089745 scopus 로고    scopus 로고
    • Role of natural-killer group 2 member D ligands and intercellular adhesion molecule 1 in natural killer cell-mediated lysis of murine embryonic stem cells and embryonic stem cell-derived cardiomyocytes
    • Frenzel LP, Abdullah Z, Kriegeskorte AK, Dieterich R, Lange N, Busch DH, Kronke M, Utermohlen O, Hescheler J, Saric T: Role of natural-killer group 2 member D ligands and intercellular adhesion molecule 1 in natural killer cell-mediated lysis of murine embryonic stem cells and embryonic stem cell-derived cardiomyocytes. Stem Cells 2009;27:307-316.
    • (2009) Stem Cells , vol.27 , pp. 307-316
    • Frenzel, L.P.1    Abdullah, Z.2    Kriegeskorte, A.K.3    Dieterich, R.4    Lange, N.5    Busch, D.H.6    Kronke, M.7    Utermohlen, O.8    Hescheler, J.9    Saric, T.10
  • 23
    • 0028365627 scopus 로고
    • Cardiomyocytes differentiated in vitro from embryonic stem cells developmentally express cardiac-specific genes and ionic currents
    • Maltsev VA, Wobus AM, Rohwedel J, Bader M, Hescheler J: Cardiomyocytes differentiated in vitro from embryonic stem cells developmentally express cardiac-specific genes and ionic currents. Circ Res 1994;75:233-244.
    • (1994) Circ Res , vol.75 , pp. 233-244
    • Maltsev, V.A.1    Wobus, A.M.2    Rohwedel, J.3    Bader, M.4    Hescheler, J.5
  • 25
    • 0027718107 scopus 로고
    • Embryonic stem cells differentiate in vitro into cardiomyocytes representing sinusnodal, atrial and ventricular cell types
    • Maltsev VA, Rohwedel J, Hescheler J, Wobus AM: Embryonic stem cells differentiate in vitro into cardiomyocytes representing sinusnodal, atrial and ventricular cell types. Mech Dev 1993;44:41-50.
    • (1993) Mech Dev , vol.44 , pp. 41-50
    • Maltsev, V.A.1    Rohwedel, J.2    Hescheler, J.3    Wobus, A.M.4
  • 27
    • 0042161933 scopus 로고    scopus 로고
    • Sizing up the heart: Development redux in disease
    • Olson EN, Schneider MD: Sizing up the heart: development redux in disease. Genes Dev 2003;17:1937-1956.
    • (2003) Genes Dev , vol.17 , pp. 1937-1956
    • Olson, E.N.1    Schneider, M.D.2
  • 29
    • 77349087843 scopus 로고    scopus 로고
    • The anti-inflammatory effect of baicalin on hypoxia/reoxygenation and TNF-alpha induced injury in cultural rat cardiomyocytes
    • Lin L, Wu XD, Davey AK, Wang J: The anti-inflammatory effect of baicalin on hypoxia/reoxygenation and TNF-alpha induced injury in cultural rat cardiomyocytes. Phytother Res 2010;24:429-437.
    • (2010) Phytother Res , vol.24 , pp. 429-437
    • Lin, L.1    Wu, X.D.2    Davey, A.K.3    Wang, J.4
  • 31
    • 78649666101 scopus 로고    scopus 로고
    • Differential gene expressions in atrial and ventricular myocytes: Insights into the road of applying embryonic stem cell-derived cardiomyocytes for future therapies
    • Ng SY, Wong CK, Tsang SY: Differential gene expressions in atrial and ventricular myocytes: insights into the road of applying embryonic stem cell-derived cardiomyocytes for future therapies. Am J Physiol Cell Physiol 2010;299:C1234-1249.
    • (2010) Am J Physiol Cell Physiol , vol.299
    • Ng, S.Y.1    Wong, C.K.2    Tsang, S.Y.3
  • 32
    • 0038030927 scopus 로고    scopus 로고
    • Development of heart muscle-cell diversity: A help or a hindrance for phenotyping embryonic stem cell-derived cardiomyocytes
    • Fijnvandraat AC, Lekanne Deprez RH, Moorman AF: Development of heart muscle-cell diversity: a help or a hindrance for phenotyping embryonic stem cell-derived cardiomyocytes. Cardiovasc Res 2003;58:303-312.
    • (2003) Cardiovasc Res , vol.58 , pp. 303-312
    • Fijnvandraat, A.C.1    Lekanne Deprez, R.H.2    Moorman, A.F.3
  • 33
    • 0029090829 scopus 로고
    • Myogenic and morphogenetic defects in the heart tubes of murine embryos lacking the homeo box gene Nkx2-5
    • Lyons I, Parsons LM, Hartley L, Li R, Andrews JE, Robb L, Harvey RP: Myogenic and morphogenetic defects in the heart tubes of murine embryos lacking the homeo box gene Nkx2-5. Genes Dev 1995;9:1654-1666.
    • (1995) Genes Dev , vol.9 , pp. 1654-1666
    • Lyons, I.1    Parsons, L.M.2    Hartley, L.3    Li, R.4    Andrews, J.E.5    Robb, L.6    Harvey, R.P.7
  • 34
    • 0032907924 scopus 로고    scopus 로고
    • The cardiac homeobox gene Csx/Nkx2.5 lies genetically upstream of multiple genes essential for heart development
    • Tanaka M, Chen Z, Bartunkova S, Yamasaki N, Izumo S: The cardiac homeobox gene Csx/Nkx2.5 lies genetically upstream of multiple genes essential for heart development. Development 1999;126:1269-1280.
    • (1999) Development , vol.126 , pp. 1269-1280
    • Tanaka, M.1    Chen, Z.2    Bartunkova, S.3    Yamasaki, N.4    Izumo, S.5
  • 36
    • 0030799792 scopus 로고    scopus 로고
    • The cardiac transcription factors Nkx2-5 and GATA-4 are mutual cofactors
    • Durocher D, Charron F, Warren R, Schwartz RJ, Nemer M: The cardiac transcription factors Nkx2-5 and GATA-4 are mutual cofactors. EMBO J 1997;16:5687-5696.
    • (1997) EMBO J , vol.16 , pp. 5687-5696
    • Durocher, D.1    Charron, F.2    Warren, R.3    Schwartz, R.J.4    Nemer, M.5
  • 37
    • 0031844382 scopus 로고    scopus 로고
    • The cardiac tissue-restricted homeobox protein Csx/Nkx2.5 physically associates with the zinc finger protein GATA4 and cooperatively activates atrial natriuretic factor gene expression
    • Lee Y, Shioi T, Kasahara H, Jobe SM, Wiese RJ, Markham BE, Izumo S: The cardiac tissue-restricted homeobox protein Csx/Nkx2.5 physically associates with the zinc finger protein GATA4 and cooperatively activates atrial natriuretic factor gene expression. Mol Cell Biol 1998;18:3120-3129.
    • (1998) Mol Cell Biol , vol.18 , pp. 3120-3129
    • Lee, Y.1    Shioi, T.2    Kasahara, H.3    Jobe, S.M.4    Wiese, R.J.5    Markham, B.E.6    Izumo, S.7
  • 38
    • 0346056964 scopus 로고    scopus 로고
    • Molecular regulation of cardiac chamber-specific gene expression
    • Small EM, Krieg PA: Molecular regulation of cardiac chamber-specific gene expression. Trends Cardiovasc Med 2004;14:13-18.
    • (2004) Trends Cardiovasc Med , vol.14 , pp. 13-18
    • Small, E.M.1    Krieg, P.A.2
  • 39
    • 0035891429 scopus 로고    scopus 로고
    • The combinatorial activities of Nkx2.5 and dHAND are essential for cardiac ventricle formation
    • Yamagishi H, Yamagishi C, Nakagawa O, Harvey RP, Olson EN, Srivastava D: The combinatorial activities of Nkx2.5 and dHAND are essential for cardiac ventricle formation. Dev Biol 2001;239:190-203.
    • (2001) Dev Biol , vol.239 , pp. 190-203
    • Yamagishi, H.1    Yamagishi, C.2    Nakagawa, O.3    Harvey, R.P.4    Olson, E.N.5    Srivastava, D.6
  • 40
    • 58149239733 scopus 로고    scopus 로고
    • Roles of TGF-beta family signaling in stem cell renewal and differentiation
    • Watabe T, Miyazono K: Roles of TGF-beta family signaling in stem cell renewal and differentiation. Cell Res 2009;19:103-115.
    • (2009) Cell Res , vol.19 , pp. 103-115
    • Watabe, T.1    Miyazono, K.2
  • 41
    • 0031018002 scopus 로고    scopus 로고
    • A role for bone morphogenetic proteins in the induction of cardiac myogenesis
    • Schultheiss TM, Burch JB, Lassar AB: A role for bone morphogenetic proteins in the induction of cardiac myogenesis. Genes Dev 1997;11:451-462.
    • (1997) Genes Dev , vol.11 , pp. 451-462
    • Schultheiss, T.M.1    Burch, J.B.2    Lassar, A.B.3
  • 42
    • 33845928762 scopus 로고    scopus 로고
    • Developmental stage-specific biphasic roles of Wnt/beta-catenin signaling in cardiomyogenesis and hematopoiesis
    • Naito AT, Shiojima I, Akazawa H, Hidaka K, Morisaki T, Kikuchi A, Komuro I: Developmental stage-specific biphasic roles of Wnt/beta-catenin signaling in cardiomyogenesis and hematopoiesis. Proc Natl Acad Sci USA 2006;103:19812-19817.
    • (2006) Proc Natl Acad Sci USA , vol.103 , pp. 19812-19817
    • Naito, A.T.1    Shiojima, I.2    Akazawa, H.3    Hidaka, K.4    Morisaki, T.5    Kikuchi, A.6    Komuro, I.7
  • 43
    • 69249121687 scopus 로고    scopus 로고
    • Wnt3a-induced mesoderm formation and cardiomyogenesis in human embryonic stem cells
    • Tran TH, Wang X, Browne C, Zhang Y, Schinke M, Izumo S, Burcin M: Wnt3a-induced mesoderm formation and cardiomyogenesis in human embryonic stem cells. Stem Cells 2009;27:1869-1878.
    • (2009) Stem Cells , vol.27 , pp. 1869-1878
    • Tran, T.H.1    Wang, X.2    Browne, C.3    Zhang, Y.4    Schinke, M.5    Izumo, S.6    Burcin, M.7
  • 46
    • 74949106101 scopus 로고    scopus 로고
    • The combination of baicalin and baicalein enhances apoptosis via the ERK/p38 MAPK pathway in human breast cancer cells
    • Zhou QM, Wang S, Zhang H, Lu YY, Wang XF, Motoo Y, Su SB: The combination of baicalin and baicalein enhances apoptosis via the ERK/p38 MAPK pathway in human breast cancer cells. Acta Pharmacol Sin 2009;30:1648-1658.
    • (2009) Acta Pharmacol Sin , vol.30 , pp. 1648-1658
    • Zhou, Q.M.1    Wang, S.2    Zhang, H.3    Lu, Y.Y.4    Wang, X.F.5    Motoo, Y.6    Su, S.B.7
  • 47
    • 79959727338 scopus 로고    scopus 로고
    • Baicalin induces human mucoepidermoid carcinoma Mc3 cells apoptosis in vitro and in vivo
    • Xu XF, Cai BL, Guan SM, Li Y, Wu JZ, Wang Y, Liu B: Baicalin induces human mucoepidermoid carcinoma Mc3 cells apoptosis in vitro and in vivo. Invest New Drugs 2011;29:637-645.
    • (2011) Invest New Drugs , vol.29 , pp. 637-645
    • Xu, X.F.1    Cai, B.L.2    Guan, S.M.3    Li, Y.4    Wu, J.Z.5    Wang, Y.6    Liu, B.7
  • 48
    • 84878876201 scopus 로고    scopus 로고
    • Baicalin attenuates acute myocardial infarction of rats via mediating the mitogen-activated protein kinase pathway
    • Liu X, Gu J, Fan Y, Shi H, Jiang M: Baicalin attenuates acute myocardial infarction of rats via mediating the mitogen-activated protein kinase pathway. Biol Pharm Bull 2013;36:988-994.
    • (2013) Biol Pharm Bull , vol.36 , pp. 988-994
    • Liu, X.1    Gu, J.2    Fan, Y.3    Shi, H.4    Jiang, M.5
  • 50
    • 79960199325 scopus 로고    scopus 로고
    • Baicalin attenuates global cerebral ischemia/reperfusion injury in gerbils via anti-oxidative and anti-apoptotic pathways
    • Cao Y, Mao X, Sun C, Zheng P, Gao J, Wang X, Min D, Sun H, Xie N, Cai J: Baicalin attenuates global cerebral ischemia/reperfusion injury in gerbils via anti-oxidative and anti-apoptotic pathways. Brain Res Bull 2011;85:396-402.
    • (2011) Brain Res Bull , vol.85 , pp. 396-402
    • Cao, Y.1    Mao, X.2    Sun, C.3    Zheng, P.4    Gao, J.5    Wang, X.6    Min, D.7    Sun, H.8    Xie, N.9    Cai, J.10
  • 51
    • 77957258387 scopus 로고    scopus 로고
    • Neuroprotective effect of baicalin on compression spinal cord injury in rats
    • Cao Y, Li G, Wang YF, Fan ZK, Yu DS, Wang ZD, Bi YL: Neuroprotective effect of baicalin on compression spinal cord injury in rats. Brain Res 2010;1357:115-123.
    • (2010) Brain Res , vol.1357 , pp. 115-123
    • Cao, Y.1    Li, G.2    Wang, Y.F.3    Fan, Z.K.4    Yu, D.S.5    Wang, Z.D.6    Bi, Y.L.7
  • 52
    • 33846612024 scopus 로고    scopus 로고
    • Baicalin attenuates oxygen-glucose deprivation-induced injury via inhibiting NMDA receptor-mediated 5-lipoxygenase activation in rat cortical neurons
    • Ge QF, Hu X, Ma ZQ, Liu JR, Zhang WP, Chen Z, Wei EQ: Baicalin attenuates oxygen-glucose deprivation-induced injury via inhibiting NMDA receptor-mediated 5-lipoxygenase activation in rat cortical neurons. Pharmacol Res 2007;55:148-157.
    • (2007) Pharmacol Res , vol.55 , pp. 148-157
    • Ge, Q.F.1    Hu, X.2    Ma, Z.Q.3    Liu, J.R.4    Zhang, W.P.5    Chen, Z.6    Wei, E.Q.7
  • 53
    • 78751545034 scopus 로고    scopus 로고
    • Baicalin increases VEGF expression and angiogenesis by activating the ERR{alpha}/PGC-1{alpha} pathway
    • Zhang K, Lu J, Mori T, Smith-Powell L, Synold TW, Chen S, Wen W: Baicalin increases VEGF expression and angiogenesis by activating the ERR{alpha}/PGC-1{alpha} pathway. Cardiovasc Res 2011;89:426-435.
    • (2011) Cardiovasc Res , vol.89 , pp. 426-435
    • Zhang, K.1    Lu, J.2    Mori, T.3    Smith-Powell, L.4    Synold, T.W.5    Chen, S.6    Wen, W.7
  • 54
    • 84855487976 scopus 로고    scopus 로고
    • Ascorbic acid enhances the cardiac differentiation of induced pluripotent stem cells through promoting the proliferation of cardiac progenitor cells
    • Cao N, Liu Z, Chen Z, Wang J, Chen T, Zhao X, Ma Y, Qin L, Kang J, Wei B, Wang L, Jin Y, Yang HT: Ascorbic acid enhances the cardiac differentiation of induced pluripotent stem cells through promoting the proliferation of cardiac progenitor cells. Cell Res 2012;22:219-236.
    • (2012) Cell Res , vol.22 , pp. 219-236
    • Cao, N.1    Liu, Z.2    Chen, Z.3    Wang, J.4    Chen, T.5    Zhao, X.6    Ma, Y.7    Qin, L.8    Kang, J.9    Wei, B.10    Wang, L.11    Jin, Y.12    Yang, H.T.13


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