The anti-inflammatory effect of baicalin on hypoxia/reoxygenation and TNF-α induced injury in cultural rat cardiomyocytes

Phytotherapy Research

Volumn 24, Issue 3, 2010, Pages 429-437

  Lin, Lin ^a   Wu, Xiao Dong ^a   Davey, Andrew K ^b   Wang, Jiping ^b,c  

^a SOUTHEAST UNIVERSITY   (China)

^b UNIVERSITY OF SOUTH AUSTRALIA   (Australia)

^c UniSA City East Campus ^*  (Australia)

Author keywords

Baicalin; Cardiomyocytes; Hypoxia reoxygenation; IL 6; Inflammation; TNF

Indexed keywords

BAICALIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 6; SUPEROXIDE DISMUTASE; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CELL DAMAGE; CELL DEATH; CELL STRUCTURE; CELL VIABILITY; CONTROLLED STUDY; ENZYME ACTIVITY; HEART MUSCLE CELL; HYPOXIA; NONHUMAN; RAT; REOXYGENATION;

ANIMALS; CELL HYPOXIA; CELL SURVIVAL; CELLS, CULTURED; FLAVONOIDS; INTERLEUKIN-10; INTERLEUKIN-6; MYOCYTES, CARDIAC; NF-KAPPA B; OXYGEN; RATS; RATS, SPRAGUE-DAWLEY; SUPEROXIDE DISMUTASE; TUMOR NECROSIS FACTOR-ALPHA;

RATTUS;

EID: 77349087843     PISSN: 0951418X     EISSN: 10991573     Source Type: Journal    
DOI: 10.1002/ptr.3003     Document Type: Article

References (40)

1. Agnetti G, Bordoni A, Angeloni C, Leoncini E, Guarnieri C, Caldarera CM, Biagi PL, Hrelia S. 2005. Green tea modulation of inducible nitric oxide synthase in hypoxic/ reoxygenated cardiomyocytes. Biochimie 87: 457-460.
2. Amrani Y, Ammit AJ, Panettieri RA Jr. 2001. Tumor necrosis factor receptor (TNFR) 1, but not TNFR 2, mediates tumor necrosis factor-alpha-induced interleukin-6 and RANTES in human airway smooth muscle cells: role of p38 and p42/44 mitogen-activated protein kinases. Mol Pharmacol 60: 646-655.
3. Ancey C, Corbi P, Froger J, Delwail A, Wijdenes J, Gascan H, Potreau D, Lecron JC. 2002. Secretion of IL-6, IL-11 and lif by human cardiomyoaytes in primary culture. Cytokine 18: 199-205.
4. Bartoccioni E, Michaelis D, Hohlfeld R. 1994. Constitutive and cytokine-induced production of interleukin-6 by human myoblasts. Immunol Lett 42: 135-138.
5. Bowie A, O'Neill LA. 2000. Oxidative stress and nuclear factor-kB activation: a reassessment of the evidence in the light of recent discoveries. Biochem Pharmacol 59: 13-23.
6. Buja LM. 2005. Myocardial ischemia and reperfusion injury. Cardiovasc Pathol 14: 170-175.
7. Chang WT, Shao ZH, Yin JJ, Mehendale S, Wang CZ, Qin Y, Li J, Chen WJ, Chien CT, Becker LB, Vanden Hoek TL, Yuan CS. 2007. Comparative effects of flavonoids on oxidant scavenging and ischemia-reperfusion injury in cardiomyocytes. Eur J Pharmacol 566: 58-66.
8. Chaparro-Huerta V, Flores-Soto ME, Gudiño-Cabrera G, Rivera-Cervantes MC, Bitzer-Quintero OK, Beas-Zárate C. 2008. Role of p38 MAPK and proinflammatory cytokines expression in glutamate-induced neuronal death of neonatal rats. Int J Dev Neurosci 26: 487-495.
9. Chou TC, Chang LP, Li CY, Wong CS, Yang SP. 2003. The antiinflammatory and analgesic effects of baicalin in carrageenan-evoked thermal hyperalgesia. Anesth Analg 97: 1724-1729.
10. Chandrasekar B, Colston JT, Geimer J, Cortez D, Freeman GL. 2000. Induction of nuclear factor kappaB but not kappaB-responsive cytokine expression during myocardial reperfusion injury after neutropenia. Free Radic Biol Med 28:1579-1588.
11. Deten A, Volz HC, Briest W, Zimmer HG. 2002. Cardiac cytokine expression is upregulated in the acute phase after myocardial infarction. Experimental studies in rats. Cardiovasc Res 55:329-340.
12. 2 induced apoptosis through a novel NF-kB p50/p50 homodimer mediated signaling pathway. Biochem Biophys Res Commun 371: 626-629.
13. Dongyan Y, Li BQ, Fu T, Mikovits JA, Ruscetti FW, Wang JM. 2000. Flavonoid baicalin inhibits HIV-1 infection at the level of viral entry. Biochem Biophys Res Commun 276: 534-538.
14. Frangogiannis NG, Smith CW, Entman ML. 2002. The inflammatory response in myocardial infarction. Cardiovasc Res 53: 31-47.
15. Frangogiannis NG, Lindsey ML, Michael LH, Youker KA, Bressler RB, Mendoza LH, Spengler RN, Smith CW, Entman ML. 1998. Resident cardiac mast cells degranulate and release preformed TNF-alpha, initiating the cytokine cascade in experimental canine myocardial ischemia/reperfusion. Circulation 98:699-710.
16. Franke WW, Schumacher H, Borrmann CM, Grund C, Winter-Simanowski S, Schlechter T, Pieperhoff S, Hofmann I. 2007. The area composita of adhering junctions connecting heart muscle cells of vertebrates - III: Assembly and disintegration of intercalated disks in rat cardiomyocytes growing in culture. Eur J Cell Biol 86: 127-142.
17. Gordon JR, Galli SJ. 1990. Mast cells as a source of both preformed andimmunologically inducible TNF-alpha/ cachectin. Nature 346: 274-276.
18. Hall G, Hasday JD, Rogers TB. 2006. Regulating the regulator: NF-κB signaling in heart. J Mol Cell Cardiol 41: 580-591.
19. Han L, Xu C, Jiang C, Li H, Zhang W, Zhao Y, Zhang L, Zhang Y, Zhao W, Yang B. 2007. Effects of polyamines on apoptosis induced by simulated ischemia/reperfusion injury in cultured neonatal rat cardiomyocytes. Cell Biol Int 31: 1345-1352.
20. Ikonomidis I, Athanassopoulos G, Lekakis J, Venetsanou K, Marinou M, Stamatelopoulos K, Cokkinos DV, Nihoyannopoulos P. 2005. Myocardial ischemia induces interleukin-6 and tissue factor production in patients with coronary artery disease: a dobutamine stress echocardiography study. Circulation 112:3272-3279.
21. Ishihara R, Taketani S, Sasai-Takedatsu M, Adachi Y, Kino M, Furuya A, Hanai N, Tokunaga R, Kobayashi Y. 2000. ELISA for urinary trehalase with monoclonal antibodies: a technique for assessment of renal tubular damage. Clin Chem 46: 636-643.
22. Jacquet S, Zarrinpashneh E, Chavey A, Ginion A, Leclerc I, Viollet B, Rutter GA, Bertrand L, Marber MS. 2007. The relationship between p38 mitogen-activated protein kinase and AMP-activated protein kinase during myocardial ischemia. Cardiovasc Res 76: 465-472.
23. Kim HJ, Tsoy I, Park JM, Chung JI, Shin SC, Chang KC. 2006. Anthocyanins from soybean seed coat inhibit the expression of TNF-α-induced genes associated with ischemia/ reperfusion in endothelial cell by NF-kB-dependent pathway and reduce rat myocardial damages incurred by ischemia and reperfusion in vivo. FEBS Lett 580: 1391-1397.
24. Kosmala W, Przewlocka-Kosmala M, Mazurek W. 2005. Proinflammatory cytokines and myocardial viability in patients after acute myocardial infarction. Int J Cardiol 101: 449-456.
25. Kumar A, Takada Y, Boriek AM, Aggarwal BB. 2004. Nuclear factor-kappaB: its role in health and disease. J Mol Med 82: 434-448.
26. Krakauer T, Li BQ, Young HA. 2001. The favonoid baicalin inhibit superantigen-induced inflammatory cytokines and chemokines. FEBS Lett. 500: 52-55.
27. Lakoski SG, Liu Y, Brosnihan KB, Herrington DM. 2008. Interleukin-10 concentration and coronary heart disease (CHD) event risk in the estrogen replacement and atherosclerosis (ERA) study. Atherosclerosis 197: 443-447.
28. BQ, Fu T, Gong WH, Dunlop N, Kung H, Yan Y, Kang J, Wang JM. 2000. The flavonoid baicalin exhibits anti-inflammatory activity by binding to chemokines. Immunopharmacology 49: 295-306.
29. McCord JM, Fridovich I. 1969. Superoxide dismutase. An enzymic function for erythrocuprein (hemocuprein). J Biol Chem 244: 6049-6055.
30. Nakahata N, Kutsuwa M, Kyo R, Kubo M, Hayashi K, Ohizumi Y. 1998. Analysis of inhibitory effects of Scutellariae radix and baicalein on prostaglandin E2 production in rat C6 glioma cells. Am J Chin Med 26: 311-323.
31. Pevni D, Frolkis I, Shapira I, Schwartz D, Schwartz I, Chernichovski T, Nesher N, Uretzky G. 2008. Cardioplegic ischemia or reperfusion: Which is a main trigger for tumor necrosis factor production? Int J Cardiol 127: 186-191.
32. Sangetha S, Zuraini Z, Suryani S, Sasidharan S. 2009. In situ TEM and SEM studies on the antimicrobial activity and prevention of Candida albicans biofilm by Cassia spectabilis extract. Micron 40: 439-443.
33. Szegezdi E, Duffy A, O'Mahoney ME, Logue SE, Mylotte LA, O'Brien T, Samali A. 2006. ER stress contributes to ischemia-induced cardiomyocyte apoptpsis. Biochem Biophys Res Commun 349: 1406-1411.
34. Tanno M, Bassi R, Gorog DA, Saurin AT, Jiang J, Heads RJ, Martin JL, Davis RJ, Flavell RA, Marber MS. 2003. Diverse mechanisms of myocardial p38 mitogen-activated protein kinase activation: evidence for MKK-independent activation by a TAB1-associated mechanism contributing to injury during myocardial ischemia. Circ Res 93: 254-261.
35. Valen G, Yan ZQ, Hansson GK. 2001. Nuclear factor Kappa-B and theheart. J Am Coll Cardiol 2: 307-314.
36. Woo AY, Cheng CH, Waye MM. 2005. Baicalein protects rat cardiomyocytes from hypoxia/reoxygenation damage via a prooxidant mechanism. Cardiovasc Res 65: 244-253.
37. Wong CK, Wang CB, Ip WK, Tian YP, Lam CW. 2005. Role of p38 MAPK and NF-κB for chemokine release in coculture of human eosinophils and bronchial epithelial cells. Clin Exp Immunol 139: 90-100.
38. Wang P, Wu P, Siegel MI, Egan RW, Billah MM. 1995. Interleukin (IL)-10 inhibits nuclear factor kappa B (NF kappa B) activation in human monocytes. IL-10 and IL-4 suppress cytokine synthesis by different mechanisms. J Biol Chem 270: 9558-9563.
39. Zhang XD, Wu XD. 2007. Protective effect of baicalin on myocardial ischemia in isolated rat heart. Chin J Clin Pharmacol Ther 12: 177-181.
40. Zahler S, Massoudy P, Hartl H, Hähnel C, Meisner H, Becker BF. 1999. Acute cardiac inflammatory responses to postischemic reperfusion during cardiopulmonary bypass. Cardiovasc Res 41: 722-730.