First chemical synthesis of a scorpion α-toxin affecting sodium channels: The Aah I toxin of Androctonus australis hector

Journal of Peptide Science

Volumn 10, Issue 11, 2004, Pages 666-677

  M'Barek, Sarrah ^a   Fajloun, Ziad ^a,b   Cestèle, Sandrine ^a,c   Devaux, Christiane ^a   Mansuelle, Pascal ^a   Mosbah, Amor ^a,b   Jouirou, Besma ^a,d   Mantegazza, Massimo ^c   Van Rietschoten, Jurphaas ^a   El Ayeb, Mohamed ^d   Rochat, Hervé ^a   Sabatier, Jean Marc ^a,b   Sampieri, Francois ^a  

^a CNRS   (France)

^b Laboratoire Cellpep SA   (France)

^c DEPARTMENT OF NEUROSURGERY   (Italy)

^d PASTEUR INSTITUTE OF TUNIS   (Tunisia)

Author keywords

Aah I; Oxidation refolding; Scorpion toxin; Sodium channel; Solid phase peptide synthesis

Indexed keywords

ALPHA TOXIN; AMINO ACID; DIMETHYL SULFOXIDE; MONOCLONAL ANTIBODY; SCORPION VENOM; SODIUM CHANNEL; TROMETAMOL;

AMINO ACID SEQUENCE; ANIMAL EXPERIMENT; ARTICLE; CIRCULAR DICHROISM; CLINICAL PROTOCOL; CONTROLLED STUDY; FEMALE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IMMUNOCHEMISTRY; ISOLATION AND PURIFICATION; LETHALITY; MOLECULAR WEIGHT; MOUSE; NONHUMAN; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; RENATURATION; SCORPION; SOLID; TOXIN ANALYSIS; TOXIN STRUCTURE; TOXIN SYNTHESIS; VOLTAGE CLAMP;

ANIMALS; ANTIBODIES, MONOCLONAL; ANTIBODY AFFINITY; ELECTROPHYSIOLOGY; MICE; NEUROTOXINS; PHOSPHOLIPASE C; PROTEIN RENATURATION; SCORPION VENOMS; SCORPIONS; SODIUM CHANNEL BLOCKERS; SODIUM CHANNELS; SURVIVAL RATE;

ANDROCTONUS; ANDROCTONUS AUSTRALIS; ANDROCTONUS AUSTRALIS HECTOR; BUTHIDAE; SCORPIONES;

EID: 8644278057     PISSN: 10752617     EISSN: None     Source Type: Journal    
DOI: 10.1002/psc.582     Document Type: Article

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