PTPL1 and PKCδ contribute to proapoptotic signalling in prostate cancer cells

Cell Death and Disease

Volumn 4, Issue 4, 2013, Pages

  Castilla, C ^a   Chinchon D ^a   Medina, R ^a   Torrubia, F J ^a   Japon M A ^a   Saez C ^a  

^a HOSPITAL UNIVERSITARIO VIRGEN DEL ROCÍO   (Spain)

Author keywords

Apoptosis; PKC ; Prostate cancer; PTPL1

Indexed keywords

FAS ANTIBODY; I KAPPA B ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; NON RECEPTOR PROTEIN TYROSINE PHOSPHATASE 13; POLY(ADENOSINE DIPHOSPHATE RIBOSE); PROTEIN BCL XL; PROTEIN KINASE C DELTA; PROTEIN MCL 1; SMALL INTERFERING RNA; BCL2L1 PROTEIN, HUMAN; I KAPPA B KINASE; MYELOID CELL LEUKEMIA SEQUENCE 1 PROTEIN; PROTEIN BCL 2; PROTEIN BCL X; PTPN13 PROTEIN, HUMAN; I KAPPA B KINASE ALPHA; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PACLITAXEL; PEPTIDES AND PROTEINS; PHENETHYL ISOTHIOCYANATE; PROTEIN MCL 1S; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CANCER CELL CULTURE; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROSTATE CANCER; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; CELL DIFFERENTIATION; CELL PROLIFERATION; DRUG ANTAGONISM; GENE EXPRESSION REGULATION; GENETICS; MALE; METABOLISM; PROSTATE TUMOR; TUMOR CELL LINE; CANCER CELL; CONTROLLED STUDY; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY;

APOPTOSIS; BCL-X PROTEIN; CELL DIFFERENTIATION; CELL LINE, TUMOR; CELL PROLIFERATION; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; I-KAPPA B KINASE; MALE; NF-KAPPA B; PROSTATIC NEOPLASMS; PROTEIN KINASE C-DELTA; PROTEIN TYROSINE PHOSPHATASE, NON-RECEPTOR TYPE 13; PROTO-ONCOGENE PROTEINS C-BCL-2; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION;

EID: 84879701129     PISSN: None     EISSN: 20414889     Source Type: Journal    
DOI: 10.1038/cddis.2013.90     Document Type: Article

References (59)

1. Krysko DV, Leybaert L, Vandenabeele P, D'Herde K. Gap junctions and the propagation of cell survival and cell death signals. Apoptosis 2005; 10: 459-469
2. Rodriguez-Sinovas A, Cabestrero A, Lopez D, Torre I, Morente M, Abellan A et al. The modulatory effects of connexin 43 on cell death/survival beyond cell coupling. Prog Biophys Mol Biol 2007; 94: 219-232
3. Wei CJ, Xu X, Lo CW. Connexins and cell signaling in development and disease. Annu Rev Cell Dev Biol 2004; 20: 811-838
4. Jiang JX, Gu S. Gap junction-And hemichannel-Independent actions of connexins. Biochim Biophys Acta 2005; 1711: 208-214
5. Behrens J, Kameritsch P, Wallner S, Pohl U, Pogoda K. The carboxyl tail of Cx43 augments p38 mediated cell migration in a gap junction-Independent manner. Eur J Cell Biol 2010; 89: 828-838
6. Bates DC, Sin WC, Aftab Q, Naus CC. Connexin43 enhances glioma invasion by a mechanism involving the carboxy terminus. Glia 2007; 55: 1554-1564
7. Kameritsch P, Pogoda K, Pohl U. Channel-Independent influence of connexin 43 on cell migration. Biochim Biophys Acta 2012; 1818: 1993-2001
8. Decrock E, De Vuyst E, Vinken M, Van Moorhem M, Vranckx K, Wang N et al. Connexin 43 hemichannels contribute to the propagation of apoptotic cell death in a rat C6 glioma cell model. Cell Death Differ 2009; 16: 151-163
9. Decrock E, Vinken M, De Vuyst E, Krysko DV, D'Herde K, Vanhaecke T et al. Connexinrelated signaling in cell death: To live or let die? Cell Death Differ 2009; 16: 524-536
10. Hur KC, Shim JE, Johnson RG. A potential role for cx43-hemichannels in staurosporininduced apoptosis. Cell Commun Adhes 2003; 10: 271-277
11. Kalvelyte A, Imbrasaite A, Bukauskiene A, Verselis VK, Bukauskas FF. Connexins and apoptotic transformation. Biochem Pharmacol 2003; 66: 1661-1672
12. Plotkin LI, Bellido T. Bisphosphonate-Induced, hemichannel-mediated, anti-Apoptosis through the Src/ERK pathway: A gap junction-Independent action of connexin 43. Cell Commun Adhes 2001; 8: 377-382
13. Iacobas DA, Urban-Maldonado M, Iacobas S, Scemes E, Spray DC. Array analysis of gene expression in connexin-43 null astrocytes. Physiol Genom 2003; 15: 177-190
14. Huang RP, Hossain MZ, Huang R, Gano J, Fan Y, Boynton AL. Connexin 43 (cx43) enhances chemotherapy-Induced apoptosis in human glioblastoma cells. Int J Cancer 2001; 92: 130-138
15. Sato H, Iwata H, Takano Y, Yamada R, Okuzawa H, Nagashima Y et al. Enhanced effect of connexin 43 on cisplatin-Induced cytotoxicity in mesothelioma cells. J Pharmacol Sci 2009; 110: 466-475
16. Boengler K, Dodoni G, Rodriguez-Sinovas A, Cabestrero A, Ruiz-Meana M, Gres P et al. Connexin 43 in cardiomyocyte mitochondria and its increase by ischemic preconditioning. Cardiovasc Res 2005; 67: 234-244
17. Halestrap AP. Mitochondria and preconditioning: A connexin connectioñ Circ Res 2006; 99: 10-12
18. Li H, Brodsky S, Kumari S, Valiunas V, Brink P, Kaide J et al. Paradoxical overexpression and translocation of connexin43 in homocysteine-Treated endothelial cells. Am J Physiol Heart Circ Physiol 2002; 282: H2124-H2133
19. Rodriguez-Sinovas A, Boengler K, Cabestrero A, Gres P, Morente M, Ruiz-Meana M et al. Translocation of connexin 43 to the inner mitochondrial membrane of cardiomyocytes through the heat shock protein 90-dependent TOM pathway and its importance for cardioprotection. Circ Res 2006; 99: 93-101
20. Huang RP, Fan Y, Hossain MZ, Peng A, Zeng ZL, Boynton AL. Reversion of the neoplastic phenotype of human glioblastoma cells by connexin 43 (cx43). Cancer Res 1998; 58: 5089-5096
21. Harada K, Nonaka T, Hamada N, Sakurai H, Hasegawa M, Funayama T et al. Heavy-Ioninduced bystander killing of human lung cancer cells: Role of gap junctional intercellular communication. Cancer Sci 2009; 100: 684-688
22. Cusato K, Ripps H, Zakevicius J, Spray DC. Gap junctions remain open during cytochrome c-Induced cell death: Relationship of conductance to 'bystander' cell killing. Cell Death Differ 2006; 13: 1707-1714
23. Frank DK, Szymkowiak B, Josifovska-Chopra O, Nakashima T, Kinnally KW. Single-cell microinjection of cytochrome c can result in gap junction-mediated apoptotic cell death of bystander cells in head and neck cancer. Head Neck 2005; 27: 794-800
24. Blanc EM, Bruce-Keller AJ, Mattson MP. Astrocytic gap junctional communication decreases neuronal vulnerability to oxidative stress-Induced disruption of Ca2 homeostasis and cell death. J Neurochem 1998; 70: 958-970
25. Ozog MA, Siushansian R, Naus CC. Blocked gap junctional coupling increases glutamateinduced neurotoxicity in neuron-Astrocyte co-cultures. J Neuropathol Exp Neurol 2002; 61: 132-141
26. Yasui K, Kada K, Hojo M, Lee JK, Kamiya K, Toyama J et al. Cell-To-cell interaction prevents cell death in cultured neonatal rat ventricular myocytes. Cardiovasc Res 2000; 48: 68-76
27. Danesh-Meyer HV, Kerr NM, Zhang J, Eady EK, O'Carroll SJ, Nicholson LF et al. Connexin43 mimetic peptide reduces vascular leak and retinal ganglion cell death following retinal ischaemia. Brain 2012; 135(Part 2): 506-520
28. Moorby C, Patel M. Dual functions for connexins: Cx43 regulates growth independently of gap junction formation. Exp Cell Res 2001; 271: 238-248
29. Krutovskikh VA, Piccoli C, Yamasaki H. Gap junction intercellular communication propagates cell death in cancerous cells. Oncogene 2002; 21: 1989-1999
30. Lin JH, Weigel H, Cotrina ML, Liu S, Bueno E, Hansen AJ et al. Gap-junction-mediated propagation and amplification of cell injury. Nat Neurosci 1998; 1: 494-500
31. Cotrina ML, Kang J, Lin JH, Bueno E, Hansen TW, He L et al. Astrocytic gap junctions remain open during ischemic conditions. J Neurosci 1998; 18: 2520-2537
32. Andrade-Rozental AF, Rozental R, Hopperstad MG, Wu JK, Vrionis FD, Spray DC. Gap junctions: The 'kiss of death' and the 'kiss of life'. Brain Res Brain Res Rev 2000; 32: 308-315
33. Kameritsch P, Pogoda K, Ritter A, Munzing S, Pohl U. Gap junctional communication controls the overall endothelial calcium response to vasoactive agonists. Cardiovasc Res 2012; 93: 508-515
34. Wilson MR, Close TW, Trosko JE. Cell population dynamics (apoptosis, mitosis, and cell-cell communication) during disruption of homeostasis. Exp Cell Res 2000; 254: 257-268
35. Kameritsch P, Khandoga N, Nagel W, Hundhausen C, Lidington D, Pohl U. Nitric oxide specifically reduces the permeability of Cx37-containing gap junctions to small molecules. J Cell Physiol 2005; 203: 233-242
36. Weber PA, Chang HC, Spaeth KE, Nitsche JM, Nicholson BJ. The permeability of gap junction channels to probes of different size is dependent on connexin composition and permeant-pore affinities. Biophys J 2004; 87: 958-973
37. Elfgang C, Eckert R, Lichtenberg-Frate H, Butterweck A, Traub O, Klein RA et al. Specific permeability and selective formation of gap junction channels in connexin-Transfected HeLa cells. J Cell Biol 1995; 129: 805-817
38. Contreras JE, Sanchez HA, Veliz LP, Bukauskas FF, Bennett MV, Saez JC. Role of connexin-based gap junction channels and hemichannels in ischemia-Induced cell death in nervous tissue. Brain Res Brain Res Rev 2004; 47: 290-303
39. Plotkin LI, Manolagas SC, Bellido T. Transduction of cell survival signals by connexin-43 hemichannels. J Biol Chem 2002; 277: 8648-8657
40. Baroja-Mazo A, Barbera-Cremades M, Pelegrin P. The participation of plasma membrane hemichannels to purinergic signaling. Biochim Biophys Acta 2013; 1828: 79-93
41. Neijssen J, Pang B, Neefjes J. Gap junction-mediated intercellular communication in the immune system. Prog Biophys Mol Biol 2007; 94: 207-218
42. Foss B, Tronstad KJ, Bruserud O. Connexin-based signaling in acute myelogenous leukemia (AML). Biochim Biophys Acta 2010; 1798: 1-8
43. Orrenius S, Zhivotovsky B, Nicotera P. Regulation of cell death: The calcium-Apoptosis link. Nat Rev Mol Cell Biol 2003; 4: 552-565
44. Jiang S, Chow SC, Nicotera P, Orrenius S. Intracellular Ca2 signals activate apoptosis in thymocytes: Studies using the Ca(2)-ATPase inhibitor thapsigargin. Exp Cell Res 1994; 212: 84-92
45. Martikainen P, Kyprianou N, Tucker RW, Isaacs JT. Programmed death of nonproliferating androgen-Independent prostatic cancer cells. Cancer Res 1991; 51: 4693-4700
46. Yan J, Khanna KK, Lavin MF. Defective radiation signal transduction in ataxia-Telangiectasia cells. Int J Radiat Biol 2000; 76: 1025-1035
47. Miyamoto S, Izumi M, Hori M, Kobayashi M, Ozaki H, Karaki H et al. Xestospongin C, a selective and membrane-permeable inhibitor of IP(3) receptor, attenuates the positive inotropic effect of alpha-Adrenergic stimulation in guinea-pig papillary muscle. Br J Pharmacol 2000; 130: 650-654
48. Yamamoto K, Hashimoto K, Isomura Y, Shimohama S, Kato N. An IP3-Assisted form of Ca2-Induced Ca2 release in neocortical neurons. NeuroReport 2000; 11: 535-539
49. Kameritsch P, Pogoda K, Ritter A, Munzing S, Pohl U. Gap junctional communication controls the overall endothelial calcium response to vasoactive agonists. Cardiovasc Res 93: 508-515
50. Chien MM, Zahradka KE, Newell MK, Freed JH. Fas-Induced B cell apoptosis requires an increase in free cytosolic magnesium as an early event. J Biol Chem 1999; 274: 7059-7066
51. Scoltock AB, Bortner CD, St J Bird G, Putney JW Jr, Cidlowski JA. A selective requirement for elevated calcium in DNA degradation, but not early events in anti-Fas-Induced apoptosis. J Biol Chem 2000; 275: 30586-30596
52. Krysko DV, Mussche S, Leybaert L, D'Herde K. Gap junctional communication and connexin43 expression in relation to apoptotic cell death and survival of granulosa cells. J Histochem Cytochem 2004; 52: 1199-1207
53. Nodin C, Nilsson M, Blomstrand F. Gap junction blockage limits intercellular spreading of astrocytic apoptosis induced by metabolic depression. J Neurochem 2005; 94: 1111-1123
54. Liu B, Wang Q, Yuan DD, Hong XT, Tao L. Berberine potentizes apoptosis induced by X-rays irradiation probably through modulation of gap junctions. Chin Med J (Engl) 2011; 124: 1221-1228
55. Azzam EI, de Toledo SM, Little JB. Direct evidence for the participation of gap junctionmediated intercellular communication in the transmission of damage signals from alphaparticle irradiated to nonirradiated cells. Proc Natl Acad Sci USA 2001; 98: 473-478
56. Zhou H, Randers-Pehrson G, Suzuki M, Waldren CA, Hei TK. Genotoxic damage in non-Irradiated cells: Contribution from the bystander effect. Radiat Prot Dosimetry 2002; 99: 227-232
57. Ripps H. Cell death in retinitis pigmentosa: Gap junctions and the 'bystander' effect. Exp Eye Res 2002; 74: 327-336
58. Oyaizu N, Adachi Y, Hashimoto F, McCloskey TW, Hosaka N, Kayagaki N et al. Monocytes express Fas ligand upon CD4 cross-linking and induce CD4 T cells apoptosis: A possible mechanism of bystander cell death in HIV infection. J Immunol 1997; 158: 2456-2463
59. Laemmli UK. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 1970; 227: 680-685