Synthesis and evaluation of novel carbamate-substituted flavanone derivatives as potent acetylcholinesterase inhibitors and anti-amnestic agents

Medicinal Chemistry Research

Volumn 22, Issue 4, 2013, Pages 1648-1659

  Anand, Preet ^a   Singh, Baldev ^a  

^a PUNJABI UNIVERSITY   (India)

Author keywords

Acetylcholinesterase; Alzheimer's disease; Carbamate; Flavanone

Indexed keywords

2 (2 HYDROXYPHENYL) 5,7 DIMETHOXYCHROMAN 4 ONE; 2 (2 HYDROXYPHENYL)CHROMAN 4 ONE; 2 (3 HYDROXY 4 METHOXYPHENYL) 5,7 DIMETHOXYCHROMAN 4 ONE; 2 (3 HYDROXY 4 METHOXYPHENYL)CHROMAN 4 ONE; 2 (3 HYDROXYPHENYL) 5,7 DIMETHOXYCHROMAN 4 ONE; 2 (3 HYDROXYPHENYL)CHROMAN 4 ONE; 2 (4 HYDROXY 3 METHOXY 5 NITROPHENYL) 5,7 DIMETHOXYCHROMAN 4 ONE; 2 (4 HYDROXY 3 METHOXY 5 NITROPHENYL)CHROMAN 4 ONE; 2 (4 HYDROXY 3 METHOXYPHENYL) 5,7 DIMETHOXYCHROMAN 4 ONE; 2 (4 HYDROXY 3 METHOXYPHENYL)CHROMAN 4 ONE; 2 (4 HYDROXY 3,5 DIMETHOXYPHENYL) 5,7 DIMETHOXYCHROMAN 4 ONE; 2 (4 HYDROXY 3,5 DIMETHOXYPHENYL)CHROMAN 4 ONE; 2 (4 HYDROXYPHENYL) 5,7 DIMETHOXYCHROMAN 4 ONE; 2 (4 HYDROXYPHENYL)CHROMAN 4 ONE; 2 (4 OXOCHROMAN 2 YL)PHENYL PHENYLCARBAMATE; 2 (5' 7' DIMETHOXY 4 OXOCHROMAN 2 YL)PHENYL PHENYLCARBAMATE; 2 METHOXY 4 (4 OXOCHROMAN 2 YL)PHENYL PHENYLCARBAMATE; 2 METHOXY 5 (4 OXOCHROMAN 2 YL)PHENYL PHENYLCARBAMATE; 2 METHOXY 6 NITRO 4 (4 OXOCHROMAN 2 YL)PHENYL PHENYLCARBAMATE; 2,6 DIMETHOXY 4 (4 OXOCHROMAN 2 YL)PHENYL PHENYLCARBAMATE; 2,6 DIMETHOXY 4 (5',7' DIMETHOXY 4 OXOCHROMAN 2 YL)PHENYL PHENYLCARBAMATE; 3 (4 OXOCHROMAN 2 YL)PHENYL PHENYLCARBAMATE; 3 (5' 7' DIMETHOXY 4 OXOCHROMAN 2 YL)PHENYL PHENYLCARBAMATE; 4 (4 OXOCHROMAN 2 YL)PHENYL PHENYLCARBAMATE; 4 (5' 7' DIMETHOXY 4 OXOCHROMAN 2 YL)PHENYL PHENYLCARBAMATE; CARBAMIC ACID DERIVATIVE; CHOLINESTERASE INHIBITOR; CHROMAN DERIVATIVE; FLAVANONE DERIVATIVE; UNCLASSIFIED DRUG; UNINDEXED DRUG;

ALZHEIMER DISEASE; AMNESIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; CYCLIZATION; DRUG SCREENING; DRUG SYNTHESIS; ENZYME INHIBITION; IC 50; IN VITRO STUDY; IN VIVO STUDY; MOUSE; NONHUMAN;

EID: 84879689938     PISSN: 10542523     EISSN: 15548120     Source Type: Journal    
DOI: 10.1007/s00044-012-0162-3     Document Type: Article

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