Molecular recognition by acetylcholinesterase at the peripheral anionic site: Structure-activity relationships for inhibitions by aryl carbamates

Bioorganic and Medicinal Chemistry

Volumn 7, Issue 12, 1999, Pages 2683-2689

  Lin, Gialih ^a   Lai, Cheng Yue ^a   Liao, Wei Cheng ^a  

^a NATIONAL CHUNG HSING UNIVERSITY   (Taiwan)

Author keywords

Acetylcholinesterase inhibition; Carbamates; Peripheral site

Indexed keywords

ACETYLCHOLINESTERASE; ANION; CARBAMIC ACID DERIVATIVE; CHOLINESTERASE INHIBITOR; EDROPHONIUM; FUNCTIONAL GROUP;

ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; COMPETITIVE INHIBITION; CONTROLLED STUDY; DISSOCIATION CONSTANT; ELECTROPHORUS; ENZYME ACTIVE SITE; ENZYME CONFORMATION; ENZYME INHIBITION; ENZYME KINETICS; MOLECULAR RECOGNITION; PROTON NUCLEAR MAGNETIC RESONANCE; STRUCTURE ACTIVITY RELATION;

ACETYLCHOLINESTERASE; ANIMALS; ANIONS; CARBAMATES; CATALYTIC DOMAIN; CHOLINESTERASE INHIBITORS; EDROPHONIUM; ELECTROPHORUS; KINETICS; MAGNETIC RESONANCE SPECTROSCOPY; PROTEIN CONFORMATION; STRUCTURE-ACTIVITY RELATIONSHIP;

ELECTROPHORUS ELECTRICUS;

EID: 0033379073     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0968-0896(99)00213-8     Document Type: Article

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