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Volumn 23, Issue 15, 2013, Pages 4393-4397
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New antifungal scaffold derived from a natural pharmacophore: Synthesis of α-methylene-γ-butyrolactone derivatives and their antifungal activity against Colletotrichum lagenarium
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Author keywords
Methylene butyrolactone; Antifungal activity; Sesquiterpene lactones; Structure activity relationships
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Indexed keywords
4 PHENYL 3 PHENYL 2 METHYLENEBUTYROLACTONE DERIVATIVE;
ALPHA METHYLENE BUTYROLACTONE DERIVATIVE;
ANTIFUNGAL AGENT;
LACTONE;
SESQUITERPENOID;
UNCLASSIFIED DRUG;
ANTIFUNGAL ACTIVITY;
ARTICLE;
CARBON NUCLEAR MAGNETIC RESONANCE;
CELL LINE;
COLLETOTRICHUM LAGENARIUM;
CONTROLLED STUDY;
CROP PROTECTION;
CRYSTAL STRUCTURE;
CYTOTOXICITY;
DRUG DESIGN;
DRUG POTENCY;
DRUG SCREENING;
DRUG SELECTIVITY;
DRUG STRUCTURE;
DRUG SYNTHESIS;
HELA CELL;
HUMAN;
HUMAN CELL;
IC 50;
MASS SPECTROMETRY;
NONHUMAN;
PHARMACOPHORE;
PROTON NUCLEAR MAGNETIC RESONANCE;
STRUCTURE ACTIVITY RELATION;
X RAY DIFFRACTION;
4-BUTYROLACTONE;
ANTIFUNGAL AGENTS;
CELL LINE;
CELL SURVIVAL;
COLLETOTRICHUM;
CRYSTALLOGRAPHY, X-RAY;
DRUG DESIGN;
HELA CELLS;
HUMANS;
MICROBIAL SENSITIVITY TESTS;
MOLECULAR CONFORMATION;
STRUCTURE-ACTIVITY RELATIONSHIP;
COLLETOTRICHUM LAGENARIUM;
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EID: 84879689826
PISSN: 0960894X
EISSN: 14643405
Source Type: Journal
DOI: 10.1016/j.bmcl.2013.05.073 Document Type: Article |
Times cited : (36)
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References (48)
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