Synthesis and antiproliferative activity of a new compound containing an α-methylene-γ-lactone group

Journal of Medicinal Chemistry

Volumn 45, Issue 12, 2002, Pages 2358-2361

  González, Antonio G ^a   Silva, Margarita Hernández ^b   Padrón, Juan I ^a   León, Francisco ^a   Reyes, Eduardo ^c   Álvarez Mon, Melchor ^c   Pivel, Juan P ^d   Quintana, José ^e   Estévez, Francisco ^e   Bermejo, Jaime ^a  

^a INSTITUTO DE PRODUCTOS NATURALES Y AGROBIOLOGÍA   (Spain)

^b UNIVERSIDAD DEL BÍO BÍO   (Chile)

^c UNIVERSITY OF ALCALÁ   (Spain)

^d CSIC   (Spain)

^e UNIVERSITY OF LAS PALMAS DE GRAN CANARIA   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA METHYLENE BUTYROLACTONE DERIVATIVE; ALPHA METHYLENE GAMMA LACTONE DERIVATIVE; GAMMA LACTONE DERIVATIVE; PHLORETIC ACID; UNCLASSIFIED DRUG;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL STRAIN HL 60; CONTROLLED STUDY; DRUG ACTIVITY; DRUG EFFECT; DRUG SYNTHESIS; HUMAN; HUMAN CELL; MITOGENESIS; MONONUCLEAR CELL; NONHUMAN; SPECTROSCOPY; SPLEEN CELL; STEREOCHEMISTRY; STRUCTURE ACTIVITY RELATION; STRUCTURE ANALYSIS; TOXICITY;

4-BUTYROLACTONE; ANIMALS; ANTINEOPLASTIC AGENTS; APOPTOSIS; CELLS, CULTURED; DRUG SCREENING ASSAYS, ANTITUMOR; HUMANS; MICE; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0037030646     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm025518n     Document Type: Article

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