Synthesis and cytotoxic evaluation of a series of γ-substituted γ-aryloxymethyl-α-methylene-γ-butyrolactones against cancer cells

Pharmaceutical Research

Volumn 17, Issue 6, 2000, Pages 715-719

  Tzeng, Cheng Chyi ^a   Lee, Kuan Han ^b   Wang, Tai Chi ^b   Han, Chein Hwa ^c   Chen, Yeh Long ^a  

^a KAOHSIUNG MEDICAL UNIVERSITY   (Taiwan)

^b TAJEN INSTITUTE OF TECHNOLOGY   (Taiwan)

^c CHIA NAN UNIVERSITY OF PHARMACY AND SCIENCE   (Taiwan)

Author keywords

Cytotoxicity; Qu inoline; Quinolin 2(1H) one; methylene butyrolactones

Indexed keywords

2 (1,1' BIPHENYL 4 YL) 2,3,4,5 TETRAHYDRO 4 METHYLENE 2 [(NAPHTHALEN 2 YLOXY)METHYL] 5 OXOFURAN; 2 NAPHTHALENE; 8 QUINOLINOL; BENZENE; CARBOSTYRIL; GAMMA BUTYROLACTONE DERIVATIVE; HYDROXYL GROUP; KETONE DERIVATIVE; METHYL GROUP; POLYCYCLIC AROMATIC HYDROCARBON DERIVATIVE; QUINALDINE; QUINOLIN 2(1H) ONE; QUINOLINE; UNCLASSIFIED DRUG;

ARTICLE; CANCER CELL; CYTOTOXICITY; DRUG POTENCY; DRUG SYNTHESIS; HUMAN; HUMAN CELL; LC 50; POLYMERIZATION; PRIORITY JOURNAL; STRUCTURE ACTIVITY RELATION; THROMBOCYTE AGGREGATION INHIBITION; VASODILATATION;

4-BUTYROLACTONE; ANTINEOPLASTIC AGENTS; DRUG EVALUATION; HUMANS; MAGNETIC RESONANCE SPECTROSCOPY; STRUCTURE-ACTIVITY RELATIONSHIP; TUMOR CELLS, CULTURED;

EID: 0033838472     PISSN: 07248741     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1007534416561     Document Type: Article

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