A new sesquiterpene lactone from the roots of Saussurea lappa: Structure-anticancer activity study

Bioorganic and Medicinal Chemistry Letters

Volumn 18, Issue 14, 2008, Pages 4015-4017

  Robinson, A ^a   Kumar, T Vijay ^a   Sreedhar, E ^a   Naidu, V G M ^a   Krishna, Sistla Rama ^a   Babu, K Suresh ^a   Srinivas, P V ^a   Rao, J Madhusudana ^a  

^a INDIAN INSTITUTE OF CHEMICAL TECHNOLOGY   (India)

Author keywords

Cyclocostunolide; Anticancer activity; Costunolide; Costus roots; Saussurea lappa

Indexed keywords

BETA CYCLOCOSTUNOLIDE; CARBENE; COSTUNOLIDE; DEHYDROCOSTUSLACTONE; DIHYDROCOSTUNOLIDE; GAMMA LACTONE DERIVATIVE; HEXANE; ISODIHYDROCOSTUNOLIDE; SAUSSUREA LAPPA EXTRACT; SESQUITERPENE LACTONE DERIVATIVE; SODIUM DERIVATIVE;

ADDITION REACTION; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL CULTURE; CARBON NUCLEAR MAGNETIC RESONANCE; COSTUS; DRUG CYTOTOXICITY; DRUG ISOLATION; DRUG POTENCY; DRUG SYNTHESIS; HUMAN; HUMAN CELL; IC 50; IN VITRO STUDY; INFRARED SPECTROSCOPY; MEDICINAL PLANT; NONHUMAN; NUCLEAR OVERHAUSER EFFECT; PLANT ROOT; PROTON NUCLEAR MAGNETIC RESONANCE; SAUSSUREA LAPPA; STRUCTURE ACTIVITY RELATION; TRADITIONAL MEDICINE;

ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; CHEMISTRY, PHARMACEUTICAL; DRUG SCREENING ASSAYS, ANTITUMOR; HUMANS; INHIBITORY CONCENTRATION 50; LACTONES; MAGNETIC RESONANCE SPECTROSCOPY; MASS SPECTROMETRY; PLANT EXTRACTS; PLANT ROOTS; SAUSSUREA; SESQUITERPENES; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP;

COSTUS; SAUSSUREA LAPPA;

EID: 47149101774     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2008.06.008     Document Type: Article

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