Fluid flow shear stress upregulates prostanoid receptor EP2 but not EP4 in murine podocytes

Prostaglandins and Other Lipid Mediators

Volumn 104-105, Issue , 2013, Pages 49-57

  Srivastava, Tarak ^a   McCarthy, Ellen T ^b   Sharma, Ram ^c   Kats, Alexander ^a   Carlton, Carol G ^b   Alon, Uri S ^a   Cudmore, Patricia A ^a   El Meanawy, Ashraf ^d   Sharma, Mukut ^c  

^a UNIVERSITY OF MISSOURI KANSAS CITY   (United States)

^b UNIVERSITY OF KANSAS MEDICAL CENTER   (United States)

^c VETERANS AFFAIRS MEDICAL CENTER   (United States)

^d MEDICAL COLLEGE OF WISCONSIN   (United States)

Author keywords

Cyclooxygenase; EP2; Fluid flow shear stress; Hyperfiltration; Podocytes; Prostaglandin E2; Prostanoid receptors

Indexed keywords

PROSTAGLANDIN E RECEPTOR 1; PROSTAGLANDIN E RECEPTOR 2; PROSTAGLANDIN E RECEPTOR 3; PROSTAGLANDIN E RECEPTOR 4;

ANIMAL CELL; CHRONIC KIDNEY DISEASE; CONFERENCE PAPER; CONTROLLED STUDY; ELECTROPHORESIS; FLUID FLOW; IMMUNOBLOTTING; IMMUNOFLUORESCENCE MICROSCOPY; IMMUNOHISTOCHEMISTRY; KIDNEY; MOUSE; NONHUMAN; PODOCYTE; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SHEAR STRESS; UPREGULATION; WESTERN BLOTTING;

ANIMALS; CELL LINE; DIFFUSION CHAMBERS, CULTURE; DINOPROSTONE; FLUORESCENT ANTIBODY TECHNIQUE; GENE EXPRESSION REGULATION; MICE; MICE, TRANSGENIC; PODOCYTES; REAL-TIME POLYMERASE CHAIN REACTION; RECEPTORS, PROSTAGLANDIN E, EP1 SUBTYPE; RECEPTORS, PROSTAGLANDIN E, EP2 SUBTYPE; RECEPTORS, PROSTAGLANDIN E, EP4 SUBTYPE; STRESS, MECHANICAL;

EID: 84879689638     PISSN: 10988823     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.prostaglandins.2012.11.001     Document Type: Conference Paper

References (58)

1. R. Rodewald, and M.J. Karnovsky Porous substructure of the glomerular slit diaphragm in the rat and mouse J Cell Biol 60 1974 423 433
2. S.J. Shankland, J.W. Pippin, J. Reiser, and P. Mundel Podocytes in culture: past, present, and future Kidney Int 72 2007 26 36 (Pubitemid 47014453)
3. C. Faul, K. Asanuma, E. Yanagida-Asanuma, K. Kim, and P. Mundel Actin up: regulation of podocyte structure and function by components of the actin cytoskeleton Trends Cell Biol 17 2007 428 437 (Pubitemid 47499042)
4. N. Endlich, and K. Endlich Stretch, tension and adhesion - adaptive mechanisms of the actin cytoskeleton in podocytes Eur J Cell Biol 85 2006 229 234
5. C. Friedrich, N. Endlich, W. Kriz, and K. Endlich Podocytes are sensitive to fluid shear stress in vitro Am J Physiol Renal Physiol 291 2006 F856 F865 (Pubitemid 44506982)
6. N. Endlich, K.R. Kress, and J. Reiser Podocytes respond to mechanical stress in vitro J Am Soc Nephrol 12 2001 413 422 (Pubitemid 32180009)
7. R.V. Durvasula, A.T. Petermann, and K. Hiromura Activation of a local tissue angiotensin system in podocytes by mechanical strain Kidney Int 65 2004 30 39 (Pubitemid 38037489)
8. 2 is crucial in the response of podocytes to fluid flow shear stress J Cell Commun Signal 4 2010 79 90
9. L.C. Martineau, L.I. McVeigh, B.J. Jasmin, and C.R. Kennedy p38 MAP kinase mediates mechanically induced COX-2 and PG EP4 receptor expression in podocytes: implications for the actin cytoskeleton Am J Physiol Renal Physiol 286 4 2004 F693 F701 (Pubitemid 38365088)
10. R.K. Zalups The Os/+ mouse: a genetic animal model of reduced renal mass Am J Pathol 264 1993 F53 F60 (Pubitemid 23059088)
11. C. He, R.K. Zalups, D.A. Henderson, G.E. Striker, and L.J. Striker Molecular analysis of spontaneous glomerulosclerosis in Os/+ mice, a model with reduced nephron mass Am J Pathol 269 1995 F266 F273
12. C. Esposito, C.J. He, G.E. Striker, R.K. Zalups, and L.J. Striker Nature and severity of the glomerular response to nephron reduction is strain-dependent in mice Am J Pathol 154 1999 891 897 (Pubitemid 29122608)
13. G. Celsi, J. Savin, J.I. Henter, and M. Sohtell The contribution of ultrafiltration pressure for glomerular hyperfiltration in young nephrectomized rats Acta Physiol Scand 141 1991 483 487
14. G. Celsi, L. Larsson, I. Seri, V. Savin, and A. Aperia Glomerular adaptation in uninephrectomized young rats Pediatr Nephrol 3 1989 280 285 (Pubitemid 19171758)
15. B.M. Brenner Nephron adaptation to renal injury or ablation Am J Pathol 249 1985 F324 F337 (Pubitemid 16225762)
16. B.M. Brenner, and H.S. Mackenzie Nephron mass as a risk factor for progression of renal disease Kidney Int Suppl 63 1997 S124 S127 (Pubitemid 28020450)
17. B.M. Brenner, E.V. Lawler, and H.S. Mackenzie The hyperfiltration theory: a paradigm shift in nephrology Kidney Int 49 1996 1774 1777 (Pubitemid 26186610)
18. H. Scholz Prostaglandins Am J Physiol Regul Integr Comp Physiol 285 2003 R512 R514 (Pubitemid 37040554)
19. H. Vitzthum, I. Abt, S. Einhellig, and A. Kurtz Gene expression of prostanoid forming enzymes along the rat nephron Kidney Int 62 2002 1570 1581 (Pubitemid 35286264)
20. S. Narumiya, Y. Sugimoto, and F. Ushikubi Prostanoid receptors: structures, properties, and functions Physiol Rev 79 1999 1193 1226 (Pubitemid 29473315)
21. S. Narumiya, and A. Ichikawa Distribution and function of prostanoids receptors: studies from knockout mice Prog Lipid Res 39 2000 289 314 (Pubitemid 30336470)
22. M. Negishi, Y. Sugimoto, and A. Ichikawa Molecular mechanisms of diverse actions of prostanoid receptors Biochim Biophys Acta 1259 1995 109 119
23. M.D. Breyer, H.R. Jacobson, and R.M. Breyer Functional and molecular aspects of renal prostaglandin receptors J Am Soc Nephrol 7 1996 8 17 (Pubitemid 26068447)
24. M.D. Breyer, L. Davis, H.R. Jacobson, and R.M. Breyer Differential localization of prostaglandin E receptor subtypes in human kidney Am J Physiol Renal Fluid Electrolyte Physiol 270 1996 F912 F918
25. M.D. Breyer, and R.M. Breyer G protein-coupled prostanoid receptors and the kidney Annu Rev Physiol 63 2001 579 605
26. + absorption by activating the EP1 receptor J Clin Invest 102 1998 194 201 (Pubitemid 28323846)
27. R. Morath, T. Klein, H.W. Seyberth, and R.M. Nusing Immunolocalization of the four prostaglandin E-2 receptor proteins EP1, EP2, EP3, and EP4 in human kidney J Am Soc Nephrol 10 1999 1851 1860 (Pubitemid 29402505)
28. M. Bek, R. Nüsing, P. Kowark, A. Henger, P. Mundel, and H. Pavenstädt Characterization of prostanoid receptors in podocytes J Am Soc Nephrol 10 1999 2084 2093 (Pubitemid 29453485)
29. H. Cheng, X. Fan, Y. Guan, G.W. Moeckel, R. Zent, and R.C. Harris Distinct roles for basal and induced COX-2 in podocyte injury J Am Soc Nephrol 20 2009 1953 1962
30. W.H. Faour, J.F. Thibodeau, and C.R. Kennedy Mechanical stretch and prostaglandin E2 modulate critical signaling pathways in mouse podocytes Cell Signal 22 2010 1222 1230
31. E.M. Stitt-Cavanagh, W.H. Faour, and K. Takami A maladaptive role for EP4 receptors in podocytes J Am Soc Nephrol 21 2010 1678 1690
32. W.H. Faour, K. Gomi, and C.R. Kennedy PGE(2) induces COX-2 expression in podocytes via the EP4 receptor through a PKA-independent mechanism Cell Signal 20 2008 2156 2164
33. P. Mundel, H.W. Heid, T.M. Mundel, M. Krüger, J. Reiser, and W. Kriz Synaptopodin: an actin-associated protein in telencephalic dendrites and renal podocytes J Cell Biol 139 1997 193 204 (Pubitemid 27444091)
34. J.G. McGarry, J. Klein-Nulend, M.G. Mullender, and P.J. Prendergast A comparison of strain and fluid shear stress in stimulating bone cell responses - a computational and experimental study FASEB J 19 2005 482 484 (Pubitemid 40316557)
35. E.T. McCarthy, and M. Sharma Indomethacin protects permeability barrier from focal segmental glomerulosclerosis serum Kidney Int 61 2002 534 541 (Pubitemid 34102593)
36. T. Srivastava, E.T. McCarthy, R. Sharma, and M. Sharma Indomethacin blocks the fluid flow shear stress (FFSS)-induced increase in glomerular albumin permeability (Palb) in vitro Abstract# 1276. ASN annual meeting Philadelphia 2011
37. K.A. Nath, D.H. Chmielewski, and T.H. Hostetter Regulatory role of prostanoids in glomerular microcirculation of remnant nephrons Am J Physiol 252 1987 F829 F837
38. J.L. Wang, H.F. Cheng, M.Z. Zhang, J.A. McKanna, and R.C. Harris Selective increase of cyclooxygenase-2 expression in a model of renal ablation Am J Physiol 275 1998 F613 F622
39. H. Golbetz, V. Black, O. Shemesh, and B.D. Myers Mechanism of the antiproteinuric effect of indomethacin in nephrotic humans Am J Physiol 256 1989 F44 F51
40. R. Vriesendorp, A.J. Donker, D. de Zeeuw, P.E. de Jong, G.K. van der Hem, and J.R. Brentjens Effects of nonsteroidal anti-inflammatory drugs on proteinuria Am J Med 81 1986 84 94 (Pubitemid 16006985)
41. R. Vriesendorp, A.J. Donker, D. de Zeeuw, P.E. de Jong, and G.K. van der Hem Antiproteinuric effect of naproxen and indomethacin. A double-blind crossover study Am J Nephrol 5 1985 236 242 (Pubitemid 15048604)
42. J.A. Velosa, V.E. Torres, J.V. Donadio Jr., R.D. Wagoner, K.E. Holley, and K.P. Offord Treatment of severe nephrotic syndrome with meclofenamate: an uncontrolled pilot study Mayo Clin Proc 60 1985 586 592 (Pubitemid 16256790)
43. M.D. Breyer Prostaglandin E receptors and the kidney Am J Physiol Renal Physiol 279 2000 F12 F23 (Pubitemid 30619543)
44. C.D. Funk Prostaglandins and leukotrienes: advances in eicosanoid biology Science 294 2001 1871 1875 (Pubitemid 33101574)
45. Y. Sugimoto, S. Narumiya, and A. Ichikawa Distribution and function of prostanoid receptors: studies from knockout mice Prog Lipid Res 39 2000 289 314 (Pubitemid 30336470)
46. R. Morath, T. Klein, H.W. Seyberth, and R.M. Nüsing Immunolocalization of the four prostaglandin E2 receptor proteins EP1, EP2, EP3, and EP4 in human kidney J Am Soc Nephrol 10 1999 1851 1860 (Pubitemid 29402505)
47. R. Ikegami, Y. Sugimoto, and E. Segi The expression of prostaglandin E receptors EP2 and EP4 and their different regulation by lipopolysaccharide in C3H/HeN peritoneal macrophages J Immunol 166 2001 4689 4696 (Pubitemid 32233756)
48. M. Katsuyama, R. Ikegami, H. Karahashi, F. Amano, Y. Sugimoto, and A. Ichikawa Characterization of the LPS-stimulated expression of EP2 and EP4 prostaglandin E receptors in mouse macrophage-like cell line, J774.1 Biochem Biophys Res Commun 251 1998 727 731 (Pubitemid 28512778)
49. P.P. Cherian, B. Cheng, S. Gu, E. Sprague, L.F. Bonewald, and J.X. Jiang Effects of mechanical strain on the function of Gap junctions in osteocytes are mediated through the prostaglandin EP2 receptor J Biol Chem 44 2003 43146 43156 (Pubitemid 37345933)
50. M.A. Kamel, J.L. Picconi, N. Lara-Castillo, and M.L. Johnson Activation of β-catenin signaling in MLO-Y4 osteocytic cells versus 2T3 osteoblastic cells by fluid flow shear stress and PGE2: implications for the study of mechanosensation in bone Bone 47 2010 872 881
51. B. Cheng, Y. Kato, and S. Zhao PGE(2) is essential for gap junction-mediated intercellular communication between osteocyte-like MLO-Y4 cells in response to mechanical strain Endocrinology 142 2001 3464 3473 (Pubitemid 32681754)
52. N. Nishigaki, M. Negishi, and A. Ichikawa Two Gs-coupled prostaglandin E receptor subtypes, EP2 and EP4, differ in desensitization and sensitivity to the metabolic inactivation of the agonist Mol Pharmacol 50 1996 1031 1037 (Pubitemid 26347726)
53. 2 in osteocyte block steroid induced apoptosis through both β-catenin and PKA pathways J Bone Miner Res 12 2010 2657 2668
54. X. Xia, N. Batra, Q. Shi, L.F. Bonewald, E. Sprague, and J.X. Jiang Prostaglandin promotion of osteocyte gap junction function through transcriptional regulation of connexin 43 by glycogen synthase kinase 3/beta-catenin signaling Mol Cell Biol 1 2010 206 219
55. J.T. Wang, J.C. Evans, and J.B. Meigs Low-grade albuminuria and the risks of hypertension and blood pressure progression Circulation 111 2005 1370 1376 (Pubitemid 40396802)
56. J.S. Christinasen, J. Gammelgaard, M. Frandsen, and H.H. Parving Increased kidney size, glomerular filtration rate and renal plasma flow in short-term insulin-dependent diabetics Diabetlogia 20 1981 451 456 (Pubitemid 11098914)
57. B.M. Brenner, D.L. Garcia, and S. Anderson Glomeruli and blood pressure: less of one, more the other Am J Hypertens 1 1988 335 347
58. G. Keller, G. Zimmer, G. Mall, E. Ritz, and K. Amann Nephron number in patients with primary hypertension N Engl J Med 348 2003 101 108 (Pubitemid 36056716)