Dual modulation of cyclooxygenase and CYP epoxygenase metabolism and acute vascular inflammation in mice

Prostaglandins and Other Lipid Mediators

Volumn 104-105, Issue , 2013, Pages 67-73

  Oni Orisan, Akinyemi ^a   Deng, Yangmei ^a   Schuck, Robert N ^a   Theken, Katherine N ^a   Edin, Matthew L ^b   Lih, Fred B ^b   Molnar, Kimberly ^a   DeGraff, Laura ^b   Tomer, Kenneth B ^b   Zeldin, Darryl C ^b   Lee, Craig R ^a  

^a UNIVERSITY OF NORTH CAROLINA   (United States)

^b NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

Author keywords

Cyclooxygenase; CYP2J2; Epoxyeicosatrienoic acid; Prostaglandin; Soluble epoxide hydrolase; Vascular inflammation

Indexed keywords

CYTOCHROME P450; CYTOCHROME P450 2J2; CYTOCHROME P450 EPOXYGENASE; ENDOTOXIN; INDOMETACIN; MYELOPEROXIDASE; PROSTAGLANDIN SYNTHASE; UNCLASSIFIED DRUG;

ACUTE VASCULAR INFLAMMATION; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; CONFERENCE PAPER; CONTROLLED STUDY; ENZYME ACTIVITY; FEMALE; GENE OVEREXPRESSION; IN VIVO STUDY; INHIBITION KINETICS; LIVER; LUNG; MALE; MODULATION; MOUSE; NONHUMAN; SIGNAL TRANSDUCTION; VASCULITIS; WILD TYPE;

8,11,14-EICOSATRIENOIC ACID; ACUTE DISEASE; ANIMALS; CYCLOOXYGENASE INHIBITORS; CYTOCHROME P-450 ENZYME SYSTEM; ENDOTHELIUM, VASCULAR; ENDOTOXINS; EPOXIDE HYDROLASES; FEMALE; GENE EXPRESSION REGULATION; INDOMETHACIN; INFLAMMATION; LIVER; LUNG; MALE; MICE; MICE, TRANSGENIC; PEROXIDASE; PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES;

EID: 84879687904     PISSN: 10988823     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.prostaglandins.2012.09.003     Document Type: Conference Paper

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