Design and synthesis of niflumic acid-based N-acylhydrazone derivatives as novel anti-inflammatory and analgesic agents

Medicinal Chemistry Research

Volumn 22, Issue 5, 2013, Pages 2411-2420

  Kheradmand, Amin ^a   Navidpour, Latifeh ^a   Shafaroodi, Hamed ^b   Saeedi Motahar, Ghazaleh ^b   Shafiee, Abbas ^a  

^a TEHRAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^b ISLAMIC AZAD UNIVERSITY   (Iran)

Author keywords

Analgesic; Anti inflammatory; Niflumic acid hydrazide

Indexed keywords

(2,4 DIMETHOXYBENZYLIDENE) 2 (3 TRIFLUROMETHYLANILINO) NICOTINIC ACID HYDRAZIDE; (3 CHLOROBENZYLIDENE) 2 (3 TRIFLUOROMETHYLANILINO) NICOTINIC ACID HYDRAZIDE; (3 CHLOROBENZYLIDENE) 2 (METHYLAMINO)NICOTINIC ACID HYDRAZIDE; (3 FLUOROBENZYLIDENE) 2 (3 TRIFLUOROMETHYLANILINO) NICOTINIC ACID HYDRAZIDE; (3 HYDROXYBENZYLIDENE) 2 (3 TRIFLUOROMETHYLANILINO) NICOTINIC ACID HYDRAZIDE; (3 METHOXYBENZYLIDENE) 2 (3 TRIFLUROMETHYLANILINO) NICOTINIC ACID HYDRAZIDE; (3 METHOXYBENZYLIDENE) 2 (METHYLAMINO)NICOTINIC ACID HYDRAZIDE; (3,4 DIHYDROXYBENZYLIDENE) 2 (3 TRIFLUOROMETHYLANILINO) NICOTINIC ACID HYDRAZIDE; (3,4 DIMETHOXYBENZYLIDENE) 2 (3 TRIFLUROMETHYLANILINO) NICOTINIC ACID HYDRAZIDE; (3,4,5 TRIMETHOXYBENZYLIDENE) 2 (3 TRIFLUOROMETHYLANILINO)NICOTINIC ACID HYDRAZIDE; (4 CHLOROBENZYLIDENE) 2 (3 TRIFLUOROMETHYLANILINO) NICOTINIC ACID HYDRAZIDE; (4 CHLOROBENZYLIDENE) 2 (METHYLAMINO)NICOTINIC ACID HYDRAZIDE; (4 FLUOROBENZYLIDENE) 2 (3 TRIFLUOROMETHYLANILINO) NICOTINIC ACID HYDRAZIDE; (4 HYDROXYBENZYLIDENE) 2 (3 TRIFLUOROMETHYLANILINO) NICOTINIC ACID HYDRAZIDE; (4 METHOXYBENZYLIDENE) 2 (3 TRIFLUROMETHYLANILINO) NICOTINIC ACID HYDRAZIDE; (PYRIDIN 3 YLMETHYLENE) 2 (3 TRIFLUOROMETHYLANILINO)NICOTINIC ACID HYDRAZIDE; (PYRIDIN 3 YLMETHYLENE) 2 (METHYLAMINO)NICOTINIC ACID HYDRAZIDE; (PYRIDIN 4 YLMETHYLENE) 2 (3 TRIFLUOROMETHYLANILINO)NICOTINIC ACID HYDRAZIDE; (PYRIDIN 4 YLMETHYLENE) 2 (METHYLAMINO)NICOTINIC ACID HYDRAZIDE; 2 (METHYLAMINO)NICOTINIC ACID HYDRAZIDE; 2 [3 (TRIFLUOROMETHYL)ANILINO]NICOTINIC ACID HYDRAZIDE; 4 DIMETHYLAMINOBENZYLIDENE 2 (3 TRIFLUOROMETHYLANILINO)NICOTINIC ACID HYDRAZIDE; ANALGESIC AGENT; ANTIINFLAMMATORY AGENT; BENZYLIDENE 2 (3 TRIFLUROMETHYLANILINO)NICOTINIC ACID HYDRAZIDE; BENZYLIDENE 2 (METHYLAMINO)NICOTINIC ACID HYDRAZIDE; CARRAGEENAN; HYDRAZONE DERIVATIVE; NIFLUMIC ACID; UNCLASSIFIED DRUG;

ANALGESIC ACTIVITY; ANTIINFLAMMATORY ACTIVITY; ARTICLE; COMPARATIVE STUDY; DRUG DESIGN; DRUG SYNTHESIS; ESTERIFICATION; HYDROGEN BOND; PAW EDEMA; STEREOCHEMISTRY; STRUCTURE ACTIVITY RELATION;

EID: 84879685771     PISSN: 10542523     EISSN: 15548120     Source Type: Journal    
DOI: 10.1007/s00044-012-0235-3     Document Type: Article

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