Design and synthesis of novel potent antinociceptive agents: Methyl-imidazolyl N-acylhydrazone derivatives

Bioorganic and Medicinal Chemistry

Volumn 8, Issue 9, 2000, Pages 2243-2248

  Figueiredo, Juliana M ^a   Cãmara, Celso De A ^b   Amarante, Emanuel G ^a   Miranda, Ana Luisa P ^a   Santos, Fúlvia M ^a   Rodrigues, Carlos R ^a   Fraga, Carlos Alberto M ^a   Barreiro, Eliezer J ^b  

^a Laboratório de Avaliação e Síntese de Substãncias Bioativas LASSBio   (Brazil)

^b FEDERAL UNIVERSITY OF RIO DE JANEIRO   (Brazil)

Author keywords

[No Author keywords available]

Indexed keywords

(4 BROMOBENZYLIDENE) 5 METHYLIMIDAZOLE 4 CARBOHYDRAZIDE; (4 DIMETHYLAMINOBENZYLIDENE) 5 METHYLIMIDAZOLE 4 CARBOHYDRAZIDE; 5 METHYLIMIDAZOLE 4 CARBOHYDRAZIDE DERIVATIVE; ANTINOCICEPTIVE AGENT; DIPYRONE; HYDRAZONE DERIVATIVE; IMIDAZOLE DERIVATIVE; INDOMETACIN; UNCLASSIFIED DRUG;

ANALGESIA; ANIMAL MODEL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG DESIGN; DRUG SYNTHESIS; IN VITRO STUDY; INFRARED SPECTROPHOTOMETRY; MOUSE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PAW EDEMA; RAT; STEREOCHEMISTRY; STRUCTURE ACTIVITY RELATION; THIN LAYER CHROMATOGRAPHY;

ACETIC ACID; ANALGESICS; ANIMALS; CARRAGEENAN; COLIC; DRUG DESIGN; EDEMA; FEMALE; HETEROCYCLIC COMPOUNDS; HYDRAZONES; IMIDAZOLES; MALE; MICE; MODELS, ANIMAL; RATS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0342646923     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0968-0896(00)00152-8     Document Type: Article

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