-
1
-
-
84863035821
-
Cancer stem cells: Distinct entities or dynamically regulated phenotypes
-
Li Y, Laterra J. Cancer stem cells: distinct entities or dynamically regulated phenotypes? Cancer Res 2012; 72: 576-580.
-
(2012)
Cancer Res
, vol.72
, pp. 576-580
-
-
Li, Y.1
Laterra, J.2
-
3
-
-
84856327694
-
Minimal residual disease in solid neoplasia: New frontier or red-herring
-
Mordant P, Loriot Y, Lahon B, Castier Y, Lesèche G, Soria JC et al. Minimal residual disease in solid neoplasia: new frontier or red-herring? Cancer Treat Rev 2012; 38: 101-110.
-
(2012)
Cancer Treat Rev
, vol.38
, pp. 101-110
-
-
Mordant, P.1
Loriot, Y.2
Lahon, B.3
Castier, Y.4
Lesèche, G.5
Soria, J.C.6
-
4
-
-
77950690962
-
Insights into minimal residual disease in cancer patients: Implications for anti-cancer therapies
-
Mü ller V, Alix-Panabières C, Pantel K. Insights into minimal residual disease in cancer patients: implications for anti-cancer therapies. Eur J Cancer 2010; 46: 1189-1197.
-
(2010)
Eur J Cancer
, vol.46
, pp. 1189-1197
-
-
Mü Ller, V.1
Alix-Panabières, C.2
Pantel, K.3
-
5
-
-
77949670310
-
Death receptor agonists as a targeted therapy for cancer
-
Wiezorek J, Holland P, Graves J. Death receptor agonists as a targeted therapy for cancer. Clin Cancer Res 2010; 16: 1701-1708.
-
(2010)
Clin Cancer Res
, vol.16
, pp. 1701-1708
-
-
Wiezorek, J.1
Holland, P.2
Graves, J.3
-
6
-
-
52649109068
-
The TRAIL apoptotic pathway in cancer onset, progression and therapy
-
Johnstone RW, Frew AJ, Smyth MJ. The TRAIL apoptotic pathway in cancer onset, progression and therapy. Nat Rev Cancer 2008; 8: 782-798.
-
(2008)
Nat Rev Cancer
, vol.8
, pp. 782-798
-
-
Johnstone, R.W.1
Frew, A.J.2
Smyth, M.J.3
-
7
-
-
45749098451
-
To kill a tumor cell: The potential of proapoptotic receptor agonists
-
Ashkenazi A, Herbst RS. To kill a tumor cell: the potential of proapoptotic receptor agonists. J Clin Invest 2008; 118: 1979-1990.
-
(2008)
J Clin Invest
, vol.118
, pp. 1979-1990
-
-
Ashkenazi, A.1
Herbst, R.S.2
-
8
-
-
79952336885
-
Combined modality therapy with TRAIL or agonistic death receptor antibodies
-
Amm HM, Oliver PG, Lee CH, Li Y, Buchsbaum DJ. Combined modality therapy with TRAIL or agonistic death receptor antibodies. Cancer Biol Ther 2011; 11: 431-449.
-
(2011)
Cancer Biol Ther
, vol.11
, pp. 431-449
-
-
Amm, H.M.1
Oliver, P.G.2
Lee, C.H.3
Li, Y.4
Buchsbaum, D.J.5
-
9
-
-
77951751200
-
TRAIL/TRAIL-R in hematologic malignancies
-
Testa U. TRAIL/TRAIL-R in hematologic malignancies. J Cell Biochem 2010; 110: 21-34.
-
(2010)
J Cell Biochem
, vol.110
, pp. 21-34
-
-
Testa, U.1
-
10
-
-
28944449421
-
Combining proteasome inhibition with TNF-related apoptosisinducing ligand (Apo2L/TRAIL) for cancer therapy
-
Sayers TJ, Murphy WJ. Combining proteasome inhibition with TNF-related apoptosisinducing ligand (Apo2L/TRAIL) for cancer therapy. Cancer Immunol Immunother 2006; 55: 76-84.
-
(2006)
Cancer Immunol Immunother
, vol.55
, pp. 76-84
-
-
Sayers, T.J.1
Murphy, W.J.2
-
11
-
-
84055212083
-
Important role of Caspase-8 for chemo-sensitivity of ALL cells
-
Ehrhardt H, Wachter F, Maurer M, Stahnke K, Jeremias I. Important role of Caspase-8 for chemo-sensitivity of ALL cells. Clin Cancer Res 2011; 17: 7605-7613.
-
(2011)
Clin Cancer Res
, vol.17
, pp. 7605-7613
-
-
Ehrhardt, H.1
Wachter, F.2
Maurer, M.3
Stahnke, K.4
Jeremias, I.5
-
12
-
-
24944458177
-
Activity of selective fully human agonistic antibodies to the TRAIL death receptors TRAIL-R1 and TRAIL-R2 in primary and cultured lymphoma cells: Induction of apoptosis and enhancement of doxorubicin-and bortezomib-induced cell death
-
Georgakis GV, Li Y, Humphreys R, Andreeff M, O'Brien S, Younes M et al. Activity of selective fully human agonistic antibodies to the TRAIL death receptors TRAIL-R1 and TRAIL-R2 in primary and cultured lymphoma cells: induction of apoptosis and enhancement of doxorubicin-and bortezomib-induced cell death. Br J Haematol 2005; 130: 501-510.
-
(2005)
Br J Haematol
, vol.130
, pp. 501-510
-
-
Georgakis, G.V.1
Li, Y.2
Humphreys, R.3
Andreeff, M.4
O'Brien, S.5
Younes, M.6
-
13
-
-
0141679399
-
Antitumor efficacy of TRA-8 anti-DR5 monoclonal antibody alone or in combination with chemotherapy and/or radiation therapy in a human breast cancer model
-
Buchsbaum DJ, Zhou T, Grizzle WE, Oliver PG, Hammond CJ, Zhang S et al. Antitumor efficacy of TRA-8 anti-DR5 monoclonal antibody alone or in combination with chemotherapy and/or radiation therapy in a human breast cancer model. Clin Cancer Res 2003; 9: 3731-3741.
-
(2003)
Clin Cancer Res
, vol.9
, pp. 3731-3741
-
-
Buchsbaum, D.J.1
Zhou, T.2
Grizzle, W.E.3
Oliver, P.G.4
Hammond, C.J.5
Zhang, S.6
-
14
-
-
0034551746
-
Antileukemic drugs increase death receptor 5 levels and enhance Apo-2L-induced apoptosis of human acute leukemia cells
-
Wen J, Ramadevi N, Nguyen D, Perkins C, Worthington E, Bhalla K. Antileukemic drugs increase death receptor 5 levels and enhance Apo-2L-induced apoptosis of human acute leukemia cells. Blood 2000; 96: 3900-3906.
-
(2000)
Blood
, vol.96
, pp. 3900-3906
-
-
Wen, J.1
Ramadevi, N.2
Nguyen, D.3
Perkins, C.4
Worthington, E.5
Bhalla, K.6
-
15
-
-
77953289301
-
New insights into p53 activation
-
Brooks CL, Gu W. New insights into p53 activation. Cell Res 2010; 20: 614-621.
-
(2010)
Cell Res
, vol.20
, pp. 614-621
-
-
Brooks, C.L.1
Gu, W.2
-
16
-
-
33749459941
-
Gene-specific mechanisms of p53 transcriptional control and prospects for cancer therapy
-
Resnick-Silverman L, Manfredi JJ. Gene-specific mechanisms of p53 transcriptional control and prospects for cancer therapy. J Cell Biochem 2006; 99: 679-689.
-
(2006)
J Cell Biochem
, vol.99
, pp. 679-689
-
-
Resnick-Silverman, L.1
Manfredi, J.J.2
-
17
-
-
0031253977
-
KILLER/DR5 is a DNA damage inducible p53-regulated death receptor gene
-
Wu GS, Burns TF, McDonald ER 3rd, Jiang W, Meng R, Krantz ID et al. KILLER/DR5 is a DNA damage inducible p53-regulated death receptor gene. Nat Genet 1997; 17: 141-143.
-
(1997)
Nat Genet
, vol.17
, pp. 141-143
-
-
Wu, G.S.1
Burns, T.F.2
McDonald III, E.R.3
Jiang, W.4
Meng, R.5
Krantz, I.D.6
-
18
-
-
82955207718
-
Optimized anti-tumor effects of anthracyclines plus vinca alkaloids using a novel, mechanism-based application schedule
-
Ehrhardt H, Schrembs D, Moritz C, Wachter F, Haldar S, Graubner U et al. Optimized anti-tumor effects of anthracyclines plus vinca alkaloids using a novel, mechanism-based application schedule. Blood 2011; 118: 6123-6131.
-
(2011)
Blood
, vol.118
, pp. 6123-6131
-
-
Ehrhardt, H.1
Schrembs, D.2
Moritz, C.3
Wachter, F.4
Haldar, S.5
Graubner, U.6
-
19
-
-
84860812161
-
Leukemia-initiating cells of patient-derived acute lymphoblastic leukemia xenografts are sensitive toward TRAIL
-
Castro Alves C, Terziyska N, GrunertM, Gündisch S, Graubner U, Quintanilla-Martinez L et al. Leukemia-initiating cells of patient-derived acute lymphoblastic leukemia xenografts are sensitive toward TRAIL. Blood 2012; 119: 4224-4227.
-
(2012)
Blood
, vol.119
, pp. 4224-4227
-
-
Castro Alves, C.1
Terziyska, N.2
Grunertm Gündisch, S.3
Graubner, U.4
Quintanilla-Martinez, L.5
-
20
-
-
0036052719
-
Enhanced sensitivity of G1 arrested human cancer cells suggests a novel therapeutic strategy using a combination of simvastatin and TRAIL
-
Jin Z, Dicker DT, El-Deiry WS. Enhanced sensitivity of G1 arrested human cancer cells suggests a novel therapeutic strategy using a combination of simvastatin and TRAIL. Cell Cycle 2002; 1: 82-89.
-
(2002)
Cell Cycle
, vol.1
, pp. 82-89
-
-
Jin, Z.1
Dicker, D.T.2
El-Deiry, W.S.3
-
21
-
-
1642576201
-
Sensitization for tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis by the chemopreventive agent resveratrol
-
Fulda S, Debatin KM. Sensitization for tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis by the chemopreventive agent resveratrol. Cancer Res 2004; 64: 337-346.
-
(2004)
Cancer Res
, vol.64
, pp. 337-346
-
-
Fulda, S.1
Debatin, K.M.2
-
22
-
-
34248221595
-
S-phase checkpoints regulate Apo2 ligand/TRAIL and CPT-11-induced apoptosis of prostate cancer cells
-
Ray S, Shyam S, Fraizer GC, Almasan A. S-phase checkpoints regulate Apo2 ligand/TRAIL and CPT-11-induced apoptosis of prostate cancer cells. Mol Cancer Ther 2007; 6: 1368-1378.
-
(2007)
Mol Cancer Ther
, vol.6
, pp. 1368-1378
-
-
Ray, S.1
Shyam, S.2
Fraizer, G.C.3
Almasan, A.4
-
23
-
-
34248379012
-
Impact of mutant p53 functional properties on TP53 mutation patterns and tumor phenotype: Lessons from recent developments in the IARC TP53 database
-
Petitjean A, Mathe E, Kato S, Ishioka C, Tavtigian SV, Hainaut P et al. Impact of mutant p53 functional properties on TP53 mutation patterns and tumor phenotype: lessons from recent developments in the IARC TP53 database. Hum Mutat 2007; 28: 622-629.
-
(2007)
Hum Mutat
, vol.28
, pp. 622-629
-
-
Petitjean, A.1
Mathe, E.2
Kato, S.3
Ishioka, C.4
Tavtigian, S.V.5
Hainaut, P.6
-
24
-
-
84863450256
-
NOXA as critical mediator for drug combinations in polychemotherapy
-
Ehrhardt H, Höfig I, Wachter F, Obexer P, Fulda S, Terziyska N et al. NOXA as critical mediator for drug combinations in polychemotherapy. Cell Death Dis 2012; 3: e327.
-
(2012)
Cell Death Dis
, vol.3
-
-
Ehrhardt, H.1
Höfig, I.2
Wachter, F.3
Obexer, P.4
Fulda, S.5
Terziyska, N.6
-
25
-
-
84875144889
-
Enhanced anti-tumor effects of vinca alkaloids given separately from cytostatic therapies
-
online first
-
Ehrhardt H, Pannert L, Pfeiffer S, Amtmann E, Jeremias I. Enhanced anti-tumor effects of vinca alkaloids given separately from cytostatic therapies. Br J Pharmacol 2012; 168: 1558-1569; online first.
-
(2012)
Br J Pharmaco
, vol.168
, pp. 1558-1569
-
-
Ehrhardt, H.1
Pannert, L.2
Pfeiffer, S.3
Amtmann, E.4
Jeremias, I.5
-
26
-
-
77952300119
-
Efficient shRNA delivery into B and T lymphoma cells using lentiviral vector-mediated transfer
-
Anastasov N, Klier M, Koch I, Angermeier D, Hö fler H, Fend F et al. Efficient shRNA delivery into B and T lymphoma cells using lentiviral vector-mediated transfer. J Hematop 2009; 2: 9-19.
-
(2009)
J Hematop
, vol.2
, pp. 9-19
-
-
Anastasov, N.1
Klier, M.2
Koch, I.3
Angermeier, D.4
Hö Fler, H.5
Fend, F.6
-
27
-
-
56249117299
-
Specific lentiviral shRNA-mediated knockdown of cyclin D1 in mantle cell lymphoma has minimal effects on cell survival and reveals a regulatory circuit with cyclin D2
-
Klier M, Anastasov N, Hermann A, Meindl T, Angermeier D, Raffeld M et al. Specific lentiviral shRNA-mediated knockdown of cyclin D1 in mantle cell lymphoma has minimal effects on cell survival and reveals a regulatory circuit with cyclin D2. Leukemia 2008; 22: 2097-2105.
-
(2008)
Leukemia
, vol.22
, pp. 2097-2105
-
-
Klier, M.1
Anastasov, N.2
Hermann, A.3
Meindl, T.4
Angermeier, D.5
Raffeld, M.6
-
28
-
-
38749133366
-
Cytotoxic drug-induced, p53-mediated upregulation of Caspase-8 in tumor cells
-
Ehrhardt H, Haecker S, Wittmann S, Maurer M, Borkhardt A, Toloczko A et al. Cytotoxic drug-induced, p53-mediated upregulation of Caspase-8 in tumor cells. Oncogene 2008; 27: 783-793.
-
(2008)
Oncogene
, vol.27
, pp. 783-793
-
-
Ehrhardt, H.1
Haecker, S.2
Wittmann, S.3
Maurer, M.4
Borkhardt, A.5
Toloczko, A.6
-
29
-
-
34248582829
-
Cancer cell lines as genetic models of their parent histology: Analyses based on array comparative genomic hybridization
-
Greshock J, Nathanson K, Martin AM, Zhang L, Coukos G, Weber BL et al. Cancer cell lines as genetic models of their parent histology: analyses based on array comparative genomic hybridization. Cancer Res 2007; 67: 3594-3600.
-
(2007)
Cancer Res
, vol.67
, pp. 3594-3600
-
-
Greshock, J.1
Nathanson, K.2
Martin, A.M.3
Zhang, L.4
Coukos, G.5
Weber, B.L.6
-
30
-
-
13844312493
-
Assessment of tumor characteristic gene expression in cell lines using a tissue similarity index (TSI)
-
Sandberg R, Ernberg I. Assessment of tumor characteristic gene expression in cell lines using a tissue similarity index (TSI). Proc Natl Acad Sci USA 2005; 102: 2052-2057.
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 2052-2057
-
-
Sandberg, R.1
Ernberg, I.2
-
31
-
-
0037220020
-
TP53 in hematologic cancer: Low incidence of mutations with significant clinical relevance
-
Peller S, Rotter V. TP53 in hematologic cancer: low incidence of mutations with significant clinical relevance. Hum Mutat 2003; 21: 1017-1026.
-
(2003)
Hum Mutat
, vol.21
, pp. 1017-1026
-
-
Peller, S.1
Rotter, V.2
-
32
-
-
84860813765
-
Efficient RNA interference in patients' acute lymphoblastic leukemia cells amplified as xenografts in mice
-
Höfig I, Ehrhardt H, Jeremias I. Efficient RNA interference in patients' acute lymphoblastic leukemia cells amplified as xenografts in mice. Cell Commun Signal 2012; 10: 8.
-
(2012)
Cell Commun Signal
, vol.10
, pp. 8
-
-
Höfig, I.1
Ehrhardt, H.2
Jeremias, I.3
-
33
-
-
80051886642
-
Xenografts of highly resistant leukemia recapitulate the clonal composition of the leukemogenic compartment
-
Schmitz M, Breithaupt P, Scheidegger N, Cario G, Bonapace L, Meissner B et al. Xenografts of highly resistant leukemia recapitulate the clonal composition of the leukemogenic compartment. Blood 2011; 118: 1854-1864.
-
(2011)
Blood
, vol.118
, pp. 1854-1864
-
-
Schmitz, M.1
Breithaupt, P.2
Scheidegger, N.3
Cario, G.4
Bonapace, L.5
Meissner, B.6
-
34
-
-
77958515009
-
Life or death: P53-induced apoptosis requires DNA binding cooperativity
-
Schlereth K, Charles JP, Bretz AC, Stiewe T. Life or death: p53-induced apoptosis requires DNA binding cooperativity. Cell Cycle 2010; 9: 4068-4076.
-
(2010)
Cell Cycle
, vol.9
, pp. 4068-4076
-
-
Schlereth, K.1
Charles, J.P.2
Bretz, A.C.3
Stiewe, T.4
-
35
-
-
77951942433
-
DNA binding cooperativity of p53 modulates the decision between cell-cycle arrest and apoptosis
-
Schlereth K, Beinoraviciute-Keller R, Zeitlinger MK, Bretz AC, Sauer M, Charles JP et al. DNA binding cooperativity of p53 modulates the decision between cell-cycle arrest and apoptosis. Mol Cell 2010; 38: 356-368.
-
(2010)
Mol Cell
, vol.38
, pp. 356-368
-
-
Schlereth, K.1
Beinoraviciute-Keller, R.2
Zeitlinger, M.K.3
Bretz, A.C.4
Sauer, M.5
Charles, J.P.6
-
36
-
-
77956170550
-
New insights into apoptosis signalling by Apo2L/TRAIL
-
Gonzalves F, Ashkenazi A. New insights into apoptosis signalling by Apo2L/TRAIL. Oncogene 2010; 29: 4752-4765.
-
(2010)
Oncogene
, vol.29
, pp. 4752-4765
-
-
Gonzalves, F.1
Ashkenazi, A.2
-
37
-
-
0016836859
-
Proliferation-dependent cytotoxicity of anticancer agents: A review
-
Valeriote F, van Putten L. Proliferation-dependent cytotoxicity of anticancer agents: a review. Cancer Res 1975; 35: 2619-2630.
-
(1975)
Cancer Res
, vol.35
, pp. 2619-2630
-
-
Valeriote, F.1
Van Putten, L.2
-
38
-
-
37549063419
-
Is cell death a critical end point for anticancer therapies or is cytostasis sufficient
-
Rixe O, Fojo T. Is cell death a critical end point for anticancer therapies or is cytostasis sufficient? Clin Cancer Res 2007; 13: 7280-7287.
-
(2007)
Clin Cancer Res
, vol.13
, pp. 7280-7287
-
-
Rixe, O.1
Fojo, T.2
-
39
-
-
84870478634
-
The adaptor protein FADD and the initiator Caspase-8 mediate activation of NF-kB by TRAIL
-
Grunert M, Gottschalk K, Kapahnke J, Gündisch S, Kieser A, Jeremias I. The adaptor protein FADD and the initiator Caspase-8 mediate activation of NF-kB by TRAIL. Cell Death Dis 2012; 3: e414.
-
(2012)
Cell Death Dis
, vol.3
-
-
Grunert, M.1
Gottschalk, K.2
Kapahnke, J.3
Gündisch, S.4
Kieser, A.5
Jeremias, I.6
|