-
1
-
-
33750313208
-
Cancer stem cells. Perspectives on current status and future directions: AACR Workshop on Cancer Stem Cells
-
Clarke MF, Dick JE, Dirks PB, et al. Cancer stem cells. Perspectives on current status and future directions: AACR Workshop on Cancer Stem Cells. Cancer Res. 2006;66(19):9339-9344.
-
(2006)
Cancer Res
, vol.66
, Issue.19
, pp. 9339-9344
-
-
Clarke, M.F.1
Dick, J.E.2
Dirks, P.B.3
-
2
-
-
70349638289
-
Tumour-initiating cells: Challenges and opportunities for anticancer drug discovery
-
Zhou B-BS, Zhang H, Damelin M, Geles KG, Grindley JC, Dirks PB. Tumour-initiating cells: challenges and opportunities for anticancer drug discovery. Nat Rev Drug Discov. 2009;8(10):806-823.
-
(2009)
Nat Rev Drug Discov
, vol.8
, Issue.10
, pp. 806-823
-
-
Zhou, B.-B.S.1
Zhang, H.2
Damelin, M.3
Geles, K.G.4
Grindley, J.C.5
Dirks, P.B.6
-
3
-
-
0028091194
-
A cell initiating human acute myeloid leukaemia after transplantation into SCID mice
-
DOI 10.1038/367645a0
-
Lapidot T, Sirard C, Vormoor J, et al. A cell initiating human acute myeloid leukaemia after transplantation into SCID mice. Nature. 1994;367(6464):645-648. (Pubitemid 24067706)
-
(1994)
Nature
, vol.367
, Issue.6464
, pp. 645-648
-
-
Lapidot, T.1
Sirard, C.2
Vormoor, J.3
Murdoch, B.4
Hoang, T.5
Caceres-Cortes, J.6
Minden, M.7
Paterson, B.8
Caligiuri, M.A.9
Dick, J.E.10
-
4
-
-
0030789242
-
Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell
-
DOI 10.1038/nm0797-730
-
Bonnet D, Dick JE. Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell. Nat Med. 1997;3:730-737. (Pubitemid 27298715)
-
(1997)
Nature Medicine
, vol.3
, Issue.7
, pp. 730-737
-
-
Bonnet, D.1
Dick, J.E.2
-
5
-
-
78650068497
-
Leukemia-initiating cells in human T-lymphoblastic leukemia exhibit glucocorticoid resistance
-
Chiu PPL, Jiang H, Dick JE. Leukemia-initiating cells in human T-lymphoblastic leukemia exhibit glucocorticoid resistance. Blood. 2010;116(24):5268-5279.
-
(2010)
Blood
, vol.116
, Issue.24
, pp. 5268-5279
-
-
Chiu, P.P.L.1
Jiang, H.2
Dick, J.E.3
-
6
-
-
15244341393
-
Dexamethasone resistance in B-cell precursor childhood acute lymphoblastic leukemia occurs downstream of ligand-induced nuclear translocation of the glucocorticoid receptor
-
DOI 10.1182/blood-2004-05-2023
-
Bachmann PS, Gorman R, MacKenzie KL, Lutze-Mann L, Lock RB. Dexamethasone resistance in B-cell precursor childhood acute lymphoblastic leukemia occurs downstream of ligand-induced nuclear translocation of the glucocorticoid receptor. Blood. 2005;105(6):2519-2526. (Pubitemid 40387054)
-
(2005)
Blood
, vol.105
, Issue.6
, pp. 2519-2526
-
-
Bachmann, P.S.1
Gorman, R.2
MacKenzie, K.L.3
Lutze-Mann, L.4
Lock, R.B.5
-
7
-
-
77952566819
-
High BAALC expression predicts chemoresistance in adult B-precursor acute lymphoblastic leukemia
-
Kü hnl A, Gökbuget N, Stroux A, et al. High BAALC expression predicts chemoresistance in adult B-precursor acute lymphoblastic leukemia. Blood. 2010;115(18):3737-3744.
-
(2010)
Blood
, vol.115
, Issue.18
, pp. 3737-3744
-
-
Kühnl, A.1
Gökbuget, N.2
Stroux, A.3
-
8
-
-
77956170550
-
New insights into apoptosis signaling by Apo2L/TRAIL
-
Gonzalvez F, Ashkenazi A. New insights into apoptosis signaling by Apo2L/TRAIL. Oncogene. 2010;29(34):4752-4765.
-
(2010)
Oncogene
, vol.29
, Issue.34
, pp. 4752-4765
-
-
Gonzalvez, F.1
Ashkenazi, A.2
-
9
-
-
29244483111
-
TRAIL receptor-selective mutants signal to apoptosis via TRAIL-R1 in primary lymphoid malignancies
-
DOI 10.1158/0008-5472.CAN-05-2801
-
MacFarlane M, Kohlhaas SL, Sutcliffe MJ, Dyer MJS, Cohen GM. TRAIL receptor-selective mutants signal to apoptosis via TRAIL-R1 in primary lymphoid malignancies. Cancer Res. 2005;65(24):11265-11270. (Pubitemid 41821680)
-
(2005)
Cancer Research
, vol.65
, Issue.24
, pp. 11265-11270
-
-
MacFarlane, M.1
Kohlhaas, S.L.2
Sutcliffe, M.J.3
Dyer, M.J.S.4
Cohen, G.M.5
-
10
-
-
0034989624
-
In vitro susceptibility to TRAIL-induced apoptosis of acute leukemia cells in the context of TRAIL receptor gene expression and constitutive NF-κB activity
-
DOI 10.1038/sj.leu.2402131
-
Wuchter C, Krappmann D, Cai Z, et al. In vitro susceptibility to TRAIL-induced apoptosis of acute leukemia cells in the context of TRAIL receptor gene expression and constitutive NF-κB activity. Leukemia. 2001;15(6):921-928. (Pubitemid 32529892)
-
(2001)
Leukemia
, vol.15
, Issue.6
, pp. 921-928
-
-
Wuchter, C.1
Krappmann, D.2
Cai, Z.3
Ruppert, V.4
Scheidereit, C.5
Dorken, B.6
Ludwig, W.-D.7
Karawajew, L.8
-
11
-
-
77954659352
-
Regulatory functions of TRAIL in hematopoietic progenitors: Human umbilical cord blood and murine bone marrow transplantation
-
Mizrahi K, Stein J, Pearl-Yafe M, Kaplan O, Yaniv I, Askenasy N. Regulatory functions of TRAIL in hematopoietic progenitors: human umbilical cord blood and murine bone marrow transplantation. Leukemia. 2010;24(7):1325-1334.
-
(2010)
Leukemia
, vol.24
, Issue.7
, pp. 1325-1334
-
-
Mizrahi, K.1
Stein, J.2
Pearl-Yafe, M.3
Kaplan, O.4
Yaniv, I.5
Askenasy, N.6
-
12
-
-
84876072005
-
Targeting Apo2L/TRAIL receptors by soluble Apo2L/TRAIL
-
published online ahead of print January 8, 2011. doi:10.1016/j.canlet. 2010.11.001
-
Holland PM. Targeting Apo2L/TRAIL receptors by soluble Apo2L/TRAIL [published online ahead of print January 8, 2011]. Cancer Lett. doi:10.1016/j.canlet.2010.11.001.
-
Cancer Lett
-
-
Holland, P.M.1
-
13
-
-
77951894266
-
Phase 1b study of dulanermin (recombinant human Apo2L/TRAIL) in combination with paclitaxel, carboplatin, and bevacizumab in patients with advanced non-squamous non-small-cell lung cancer
-
Soria J-C, Smit E, Khayat D, et al. Phase 1b study of dulanermin (recombinant human Apo2L/TRAIL) in combination with paclitaxel, carboplatin, and bevacizumab in patients with advanced non-squamous non-small-cell lung cancer. J Clin Oncol. 2010;28(9):1527-1533.
-
(2010)
J Clin Oncol
, vol.28
, Issue.9
, pp. 1527-1533
-
-
Soria, J.-C.1
Smit, E.2
Khayat, D.3
-
14
-
-
78650021203
-
A Phase 1b/2 trial of mapatumumab in patients with relapsed/refractory non-Hodgkin's lymphoma
-
Younes A, Vose JM, Zelenetz AD, et al. A Phase 1b/2 trial of mapatumumab in patients with relapsed/refractory non-Hodgkin's lymphoma. Br J Cancer. 2010;103(12):1783-1787.
-
(2010)
Br J Cancer
, vol.103
, Issue.12
, pp. 1783-1787
-
-
Younes, A.1
Vose, J.M.2
Zelenetz, A.D.3
-
15
-
-
40749150603
-
Acute lymphoblastic leukaemia
-
DOI 10.1016/S0140-6736(08)60457-2, PII S0140673608604572
-
Pui C-H, Robison LL, Look AT. Acute lymphoblastic leukaemia. Lancet. 2008;371(9617):1030-1043. (Pubitemid 351389536)
-
(2008)
The Lancet
, vol.371
, Issue.9617
, pp. 1030-1043
-
-
Pui, C.-H.1
Robison, L.L.2
Look, A.T.3
-
16
-
-
0028925778
-
Defective lymphoid development in mice lacking expression of the common cytokine receptor gamma chain
-
Cao X, Shores EW, Hu-Li J, et al. Defective lymphoid development in mice lacking expression of the common cytokine receptor gamma chain. Immunity. 1995;2(3):223-238.
-
(1995)
Immunity
, vol.2
, Issue.3
, pp. 223-238
-
-
Cao, X.1
Shores, E.W.2
Hu-Li, J.3
-
17
-
-
0035499267
-
Stem cells, cancer, and cancer stem cells
-
DOI 10.1038/35102167
-
Reya T, Morrison SJ, Clarke MF, Weissman IL. Stem cells, cancer, and cancer stem cells. Nature. 2001;414(6859):105-111. (Pubitemid 33041634)
-
(2001)
Nature
, vol.414
, Issue.6859
, pp. 105-111
-
-
Reya, T.1
Morrison, S.J.2
Clarke, M.F.3
Weissman, I.L.4
-
18
-
-
45849102392
-
In Childhood Acute Lymphoblastic Leukemia, Blasts at Different Stages of Immunophenotypic Maturation Have Stem Cell Properties
-
DOI 10.1016/j.ccr.2008.05.015, PII S1535610808001888
-
le Viseur C, Hotfilder M, Bomken S, et al. In childhood acute lymphoblastic leukemia, blasts at different stages of immunophenotypic maturation have stem cell properties. Cancer Cell. 2008;14(1):47-58. (Pubitemid 351885495)
-
(2008)
Cancer Cell
, vol.14
, Issue.1
, pp. 47-58
-
-
Le, V.C.1
Hotfilder, M.2
Bomken, S.3
Wilson, K.4
Rottgers, S.5
Schrauder, A.6
Rosemann, A.7
Irving, J.8
Stam, R.W.9
Shultz, L.D.10
Harbott, J.11
Jurgens, H.12
Schrappe, M.13
Pieters, R.14
Vormoor, J.15
-
19
-
-
78149464805
-
High frequencies of leukemia stem cells in poor-outcome childhood precursor-B acute lymphoblastic leukemias
-
Morisot S, Wayne AS, Bohana-Kashtan O, et al. High frequencies of leukemia stem cells in poor-outcome childhood precursor-B acute lymphoblastic leukemias. Leukemia. 2010;24(11):1859-1866.
-
(2010)
Leukemia
, vol.24
, Issue.11
, pp. 1859-1866
-
-
Morisot, S.1
Wayne, A.S.2
Bohana-Kashtan, O.3
-
20
-
-
45149133254
-
CD34+CD38+CD19+ as well as CD34+CD38-CD19+ cells are leukemia-initiating cells with self-renewal capacity in human B-precursor ALL
-
DOI 10.1038/leu.2008.83, PII LEU200883
-
Kong Y, Yoshida S, Saito Y, et al. CD34+CD38+CD19+ as well as CD34+CD38+CD19+ cells are leukemia-initiating cells with self-renewal capacity in human B-precursor ALL. Leukemia. 2008;22(6):1207-1213. (Pubitemid 351833789)
-
(2008)
Leukemia
, vol.22
, Issue.6
, pp. 1207-1213
-
-
Kong, Y.1
Yoshida, S.2
Saito, Y.3
Doi, T.4
Nagatoshi, Y.5
Fukata, M.6
Saito, N.7
Yang, S.M.8
Iwamoto, C.9
Okamura, J.10
Liu, K.Y.11
Huang, X.J.12
Lu, D.P.13
Shultz, L.D.14
Harada, M.15
Ishikawa, F.16
-
21
-
-
24744462114
-
Tumor necrosis factor-related apoptosis-inducing ligand-mediated proliferation of tumor cells with receptor-proximal apoptosis defects
-
DOI 10.1158/0008-5472.CAN-04-4278
-
Baader E, Toloczko A, Fuchs U, et al. Tumor necrosis factor-related apoptosis-inducing ligand-mediated proliferation of tumor cells with receptor-proximal apoptosis defects. Cancer Res. 2005;65(17):7888-7895. (Pubitemid 41297266)
-
(2005)
Cancer Research
, vol.65
, Issue.17
, pp. 7888-7895
-
-
Baader, E.1
Toloczko, A.2
Fuchs, U.3
Schmid, I.4
Beltinger, C.5
Ehrhardt, H.6
Debatin, K.-M.7
Jeremias, I.8
-
22
-
-
85042587668
-
Small molecule XIAP inhibitors cooperate with TRAIL to induce apoptosis in childhood acute leukemia cells and overcome Bcl-2-mediated resistance
-
Fakler M, Loeder S, Vogler M, et al. Small molecule XIAP inhibitors cooperate with TRAIL to induce apoptosis in childhood acute leukemia cells and overcome Bcl-2-mediated resistance. Blood. 2009;113(8):1710-1722.
-
(2009)
Blood
, vol.113
, Issue.8
, pp. 1710-1722
-
-
Fakler, M.1
Loeder, S.2
Vogler, M.3
-
23
-
-
78751644099
-
Genetic variegation of clonal architecture and propagating cells in leukaemia
-
Anderson K, Lutz C, van Delft FW, et al. Genetic variegation of clonal architecture and propagating cells in leukaemia. Nature. 2011;469(7330):356-361.
-
(2011)
Nature
, vol.469
, Issue.7330
, pp. 356-361
-
-
Anderson, K.1
Lutz, C.2
Van Delft, F.W.3
-
24
-
-
78751661556
-
Evolution of human BCR-ABL1 lymphoblastic leukaemia-initiating cells
-
Notta F, Mullighan CG, Wang JCY, et al. Evolution of human BCR-ABL1 lymphoblastic leukaemia-initiating cells. Nature. 2011;469(7330):362-367.
-
(2011)
Nature
, vol.469
, Issue.7330
, pp. 362-367
-
-
Notta, F.1
Mullighan, C.G.2
Wang, J.C.Y.3
-
25
-
-
80051886642
-
Xenografts of highly resistant leukemia recapitulate the clonal composition of the leukemogenic compartment
-
Schmitz M, Breithaupt P, Scheidegger N, et al. Xenografts of highly resistant leukemia recapitulate the clonal composition of the leukemogenic compartment. Blood. 2011;118(7):1854-1864.
-
(2011)
Blood
, vol.118
, Issue.7
, pp. 1854-1864
-
-
Schmitz, M.1
Breithaupt, P.2
Scheidegger, N.3
-
26
-
-
35948984135
-
Chemotherapy-resistant human AML stem cells home to and engraft within the bone-marrow endosteal region
-
DOI 10.1038/nbt1350, PII NBT1350
-
Ishikawa F, Yoshida S, Saito Y, et al. Chemotherapy-resistant human AML stem cells home to and engraft within the bone-marrow endosteal region. Nat Biotechnol. 2007;25(11):1315-1321. (Pubitemid 350076512)
-
(2007)
Nature Biotechnology
, vol.25
, Issue.11
, pp. 1315-1321
-
-
Ishikawa, F.1
Yoshida, S.2
Saito, Y.3
Hijikata, A.4
Kitamura, H.5
Tanaka, S.6
Nakamura, R.7
Tanaka, T.8
Tomiyama, H.9
Saito, N.10
Fukata, M.11
Miyamoto, T.12
Lyons, B.13
Ohshima, K.14
Uchida, N.15
Taniguchi, S.16
Ohara, O.17
Akashi, K.18
Harada, M.19
Shultz, L.D.20
more..
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