메뉴 건너뛰기




Volumn 110, Issue 1, 2010, Pages 21-34

TRAIL/TRAIL-R in hematologic malignancies

Author keywords

Apoptosis; Leukemia; Lymphoma; TRAIL

Indexed keywords

AMG 655; AMG 951; APOMAB; BCR ABL PROTEIN; BEVACIZUMAB; BORTEZOMIB; CS 1008; CYTOKINE RECEPTOR AGONIST; DASATINIB; DEATH RECEPTOR 4; DEATH RECEPTOR 5; DULANERMIN; FAS LIGAND; FLICE INHIBITORY PROTEIN; IMATINIB; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LBY 135; LEXATUMAMAB; MAPATUMAMAB; MONOCLONAL ANTIBODY; NILOTINIB; PERIFOSINE; PROTEIN BCL 2; PROTEIN TYROSINE KINASE INHIBITOR; RECOMBINANT TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND; RITUXIMAB; TUMOR NECROSIS FACTOR ALPHA; TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND; TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND RECEPTOR; UNCLASSIFIED DRUG; UNINDEXED DRUG; X LINKED INHIBITOR OF APOPTOSIS;

EID: 77951751200     PISSN: 07302312     EISSN: 10974644     Source Type: Journal    
DOI: 10.1002/jcb.22549     Document Type: Review
Times cited : (40)

References (120)
  • 1
    • 0034961181 scopus 로고    scopus 로고
    • Retinoic acid-induced apoptosis in leukemia cells is mediated by paracrine action of tumor-selective death ligand TRAIL
    • DOI 10.1038/89050
    • Altucci L, Rossini A, RaffelabergerW, Reitmair A, Chomienne C, Gronemeyer H. 2001. Retinoic acid-induced apoptosis in leukaemia cells is mediated by paracrine action of tumor-selective death ligand TRAIL. Nature Med 7:680-686. (Pubitemid 32588023)
    • (2001) Nature Medicine , vol.7 , Issue.6 , pp. 680-686
    • Altucci, L.1    Rossin, A.2    Raffelsberger, W.3    Reitmair, A.4    Chomienne, C.5    Gronemeyer, H.6
  • 3
    • 0037255789 scopus 로고    scopus 로고
    • Allogeneic stem cell transplantation for chronic myeloid leukemia
    • Barrett J. 2009. Allogeneic stem cell transplantation for chronic myeloid leukemia. Semin Hematol 40:59-71.
    • (2009) Semin Hematol , vol.40 , pp. 59-71
    • Barrett, J.1
  • 4
    • 0035912109 scopus 로고    scopus 로고
    • Sensitization of resistant lymphoma cells to irradiation-induced apoptosis by the death ligand TRAIL
    • DOI 10.1038/sj.onc.1204318
    • Belka C, Schmid B, Marini P, Durand E, Rudner J, Faltin H, Bamberg M, Schulze-Osthoff K, Budach W. 2001. Sensitization of resistant lymphoma cells to irradiation-induced apoptosis by the death ligand TRAIL. Oncogene 20:2190-2196. (Pubitemid 32424014)
    • (2001) Oncogene , vol.20 , Issue.17 , pp. 2190-2196
    • Belka, C.1    Schmid, B.2    Marini, P.3    Durand, E.4    Rudner, J.5    Faltin, H.6    Bamberg, M.7    Schulze-Osthoff, K.8    Budach, W.9
  • 6
    • 70449701923 scopus 로고    scopus 로고
    • Oligomerized tumor necrosis factor-related apoptosis inducing ligand strongly induces cell death in myeloma cells, but also activates proinflammatory signaling pathways
    • Berg D, Stuhmer T, Siegmund D, Muller N, Giner T, Breiholz O, Kracht M, Bargou R, Wajant H. 2009 Oligomerized tumor necrosis factor-related apoptosis inducing ligand strongly induces cell death in myeloma cells, but also activates proinflammatory signaling pathways. FEBS J 276:6912-6927.
    • (2009) FEBS J , vol.276 , pp. 6912-6927
    • Berg, D.1    Stuhmer, T.2    Siegmund, D.3    Muller, N.4    Giner, T.5    Breiholz, O.6    Kracht, M.7    Bargou, R.8    Wajant, H.9
  • 7
    • 34848902287 scopus 로고    scopus 로고
    • Blockade of death receptor-mediated pathways early in the signaling cascade coincides with distinct apoptosis resistance in cutaneous T-cell lymphoma cells
    • DOI 10.1038/sj.jid.5700868, PII 5700868
    • Braun FK, Fecker LF, Schwarz C, Waltera P, Assaf C, Durkop H, Sterry W, Eberle J. 2007. Blockade of death receptor-mediated pathways early in the signalling cascade coincides with distinct apoptosis resistance in cutaneous T-cell lymphoma cells. J Invest Dermatol 127:2425-2437. (Pubitemid 47619746)
    • (2007) Journal of Investigative Dermatology , vol.127 , Issue.10 , pp. 2425-2437
    • Braun, F.K.1    Fecker, L.F.2    Schwarz, C.3    Walden, P.4    Assaf, C.5    Durkop, H.6    Sterry, W.7    Eberle, J.8
  • 10
    • 25844495160 scopus 로고    scopus 로고
    • Myelodysplastic syndromes: A comprehensive review
    • Catenacci DV, Schiller GJ. 2005. Myelodysplastic syndromes: A comprehensive review. Blood Rev 19:301-319.
    • (2005) Blood Rev , vol.19 , pp. 301-319
    • Catenacci, D.V.1    Schiller, G.J.2
  • 13
    • 0034533011 scopus 로고    scopus 로고
    • Expression of tumour necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) receptors and sensitivity to TRAIL-induced apoptosis in primary B-cell acute lymphoblastic leukaemia cells
    • Clodi K, Wimmer D, Li Y, Goodwin R, Jaeger U, Mann G, Gadner H, Younes A. 2000. Expression of tumour necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) receptors and sensitivity to TRAIL-induced apoptosis in primary B-cell acute lymphoblastic leukaemia cells. Br J Haematol 111:580-586.
    • (2000) Br J Haematol , vol.111 , pp. 580-586
    • Clodi, K.1    Wimmer, D.2    Li, Y.3    Goodwin, R.4    Jaeger, U.5    Mann, G.6    Gadner, H.7    Younes, A.8
  • 14
    • 47149098403 scopus 로고    scopus 로고
    • Resistance to FasL and tumor necrosis factor-related apoptosis-inducing ligand-mediated apoptosis in Sézary syndrome T cells associated with impaired death receptor and FLICE-inhibitory protein expression
    • Contassot E, Kerl K, Roques S, Shane R, Gaide O, Dupuis M, Rook A, French LE. 2008. Resistance to FasL and tumor necrosis factor-related apoptosis-inducing ligand-mediated apoptosis in Sézary syndrome T cells associated with impaired death receptor and FLICE-inhibitory protein expression. Blood 111:4780-4787.
    • (2008) Blood , vol.111 , pp. 4780-4787
    • Contassot, E.1    Kerl, K.2    Roques, S.3    Shane, R.4    Gaide, O.5    Dupuis, M.6    Rook, A.7    French, L.E.8
  • 15
    • 0036467427 scopus 로고    scopus 로고
    • Increased susceptibility to tumor initiation and metastasis in TNF-related apoptosis-inducing ligand-deficient mice
    • Cretney E, Takeda K, Yagita H, Glaccum M, Peschon JJ, Smythgy MJ. 2002. Increased susceptibility to tumor initiation and metastasis in TNF-related apoptosis inducing ligand-deficient mice. J Immunol 168:1356-1361. (Pubitemid 34094506)
    • (2002) Journal of Immunology , vol.168 , Issue.3 , pp. 1356-1361
    • Cretney, E.1    Takeda, K.2    Yagita, H.3    Glaccum, M.4    Peschon, J.J.5    Smyth, M.J.6
  • 16
    • 37049008917 scopus 로고    scopus 로고
    • Cooperation of the proapoptotic receptor agonist rhApo2L/TRAIL with the CD20 antibody rituximab against non-Hodgkin lymphoma xenografts
    • DOI 10.1182/blood-2007-02-076075
    • Daniel D, Yang B, Lawrence DA, Toptal K, Balter I, Lee WP, Gogineni A, Cole MJ, Yee SF, Ross S, Ashkenazi A. 2007. Cooperation of the proapoptotic receptor agonist rhApo2L/TRAIL with the CD20 antibody rituximab against non-Hodgkin lymphoma xenografts. Blood 110:4037-4046. (Pubitemid 350248460)
    • (2007) Blood , vol.110 , Issue.12 , pp. 4037-4046
    • Daniel, D.1    Yang, B.2    Lawrence, D.A.3    Totpal, K.4    Balter, I.5    Lee, W.P.6    Gogineni, A.7    Cole, M.J.8    Yee, S.F.9    Ross, S.10    Ashkenazi, A.11
  • 17
    • 52649101930 scopus 로고    scopus 로고
    • Perifosine synergistically enhances TRAIL-induced myeloma cell apoptosis via upregulation of death receptors
    • David E, Sinha R, Chen J, Sun SY, Kaufman JL, Lonial S. 2008. Perifosine synergistically enhances TRAIL-induced myeloma cell apoptosis via upregulation of death receptors. Clin Cancer Res 14:5080-5087.
    • (2008) Clin Cancer Res , vol.14 , pp. 5080-5087
    • David, E.1    Sinha, R.2    Chen, J.3    Sun, S.Y.4    Kaufman, J.L.5    Lonial, S.6
  • 18
    • 52049088263 scopus 로고    scopus 로고
    • Resistance to TRAIL-induced apoptosis caused by constitutional phosphorylation of AKT and PTEN in acute lymphoblastic leukemia cells
    • Dida F, Li Y, Ivano A, Deguchi T, Azuma E, Komada Y. 2008. Resistance to TRAIL-induced apoptosis caused by constitutional phosphorylation of AKT and PTEN in acute lymphoblastic leukemia cells. Exp Hematol 36:1343-1353.
    • (2008) Exp Hematol , vol.36 , pp. 1343-1353
    • Dida, F.1    Li, Y.2    Ivano, A.3    Deguchi, T.4    Azuma, E.5    Komada, Y.6
  • 19
    • 33749252583 scopus 로고    scopus 로고
    • Human inhibitor of apoptosis protein: Why XIAP is the black sheep of the family
    • Eckelman BP, Salvesen GS, Scott FL. 2006. Human inhibitor of apoptosis protein: Why XIAP is the black sheep of the family. EMBO Rep 7:988-994.
    • (2006) EMBO Rep , vol.7 , pp. 988-994
    • Eckelman, B.P.1    Salvesen, G.S.2    Scott, F.L.3
  • 20
    • 0038339094 scopus 로고    scopus 로고
    • TRAIL induced survival and proliferation in cancer cells resistant towards TRAIL-induced apoptosis mediated by NF-kB
    • DOI 10.1038/sj.onc.1206520
    • Ehrhardt H, Fulda S, Schmid I, Hischott J, Debatin KM, Jeremias I. 2003. TRAIL induced survival and proliferation in cancer cells resistant towards TRAIL-induced apoptosis mediated by NF-kB. Oncogene 22:3842-3852. (Pubitemid 36819657)
    • (2003) Oncogene , vol.22 , Issue.25 , pp. 3842-3852
    • Ehrhardt, H.1    Fulda, S.2    Schmid, I.3    Hiscott, J.4    Debatin, K.-M.5    Jeremias, I.6
  • 21
    • 9144272267 scopus 로고    scopus 로고
    • Frequent polymorphic changes but not mutations of TRAIL receptors DR4 and DR5 in mantle cell lymphoma and other B-cell lymphoid neoplasms
    • Fernandez V, Jares P, Bea S, Salaverria I, Guino E, SanJosé S, Colomer D, Ott G, Montserrat E, Campo E. 2004. Frequent polymorphic changes but not mutations of TRAIL receptors DR4 and DR5 in mantle cell lymphoma and other B-cell lymphoid neoplasms. Haematologica 89:1322-1331. (Pubitemid 39540569)
    • (2004) Haematologica , vol.89 , Issue.11 , pp. 1322-1331
    • Fernandez, V.1    Jares, P.2    Bea, S.3    Salaverria, I.4    Guino, E.5    De Sanjose, S.6    Colomer, D.7    Ott, G.8    Montserrat, E.9    Campo, E.10
  • 22
    • 38149139518 scopus 로고    scopus 로고
    • TRAIL-R deficiency in mice promotes susceptibility to chronic inflammation and tumorigenesis
    • Finnberg N, Klein-Szanto AJ, El-Deiry WS. 2008. TRAIL-R deficiency in mice promotes susceptibility to chronic inflammation and tumorigenesis. J Clin Invest 118:111-123.
    • (2008) J Clin Invest , vol.118 , pp. 111-123
    • Finnberg, N.1    Klein-Szanto, A.J.2    El-Deiry, W.S.3
  • 23
    • 85042587668 scopus 로고    scopus 로고
    • Small molecule XIAP inhibitors cooperate with TRAIL to induce apoptosis in childhood acute leukaemia cells and overcome Bcl-2-mediated resistance
    • Fakler M, Loeder S, Vogler M, Schneider K, Jeremias I, Dibatin KM, Fulda S. 2009. Small molecule XIAP inhibitors cooperate with TRAIL to induce apoptosis in childhood acute leukaemia cells and overcome Bcl-2-mediated resistance. Blood 113:1710-1722.
    • (2009) Blood , vol.113 , pp. 1710-1722
    • Fakler, M.1    Loeder, S.2    Vogler, M.3    Schneider, K.4    Jeremias, I.5    Dibatin, K.M.6    Fulda, S.7
  • 24
    • 33846243705 scopus 로고    scopus 로고
    • Edelfosine and perifosine induce selective apoptosis in multiple myeloma by recruitment of death receptors and downstream signaling molecules into lipid rafts
    • DOI 10.1182/blood-2006-04-016824
    • Gapate C, Mollinedo F. 2007. Edelfosine and perifosine induce selective apoptosis in multiple myeloma by recruitment of death receptors and downstream signaling molecules into lipid rafts. Blodd 109:711-719. (Pubitemid 46105973)
    • (2007) Blood , vol.109 , Issue.2 , pp. 711-719
    • Gajate, C.1    Mollinedo, F.2
  • 25
    • 0032717188 scopus 로고    scopus 로고
    • TRAIL is a potent inducer of apoptosis in myeloma cells derived from multiple myeloma patients and is not cytotoxic to hematopoietic stem cells
    • Gazitt Y. 1999. TRAIL is a potent inducer of apoptosis in myeloma cells derived from multiple patients and is not cytotoxic to hematopoietic stem cells. Leukemia 13:1817-1824. (Pubitemid 29535266)
    • (1999) Leukemia , vol.13 , Issue.11 , pp. 1817-1824
    • Gazitt, Y.1
  • 26
    • 63849263097 scopus 로고    scopus 로고
    • Phorbol ester-induced PKCε downmodulation sensitizes AMl cells to TRAIL-induced apoptosis and cell differentiation
    • Gobbi G, Mirandola P, Carubbi C, Micheloni C, Malinverno C, Lunghi P, Bonati A, Vitale M. 2009. Phorbol ester-induced PKCε downmodulation sensitizes AMl cells to TRAIL-induced apoptosis and cell differentiation. Blood 113:3080-3087.
    • (2009) Blood , vol.113 , pp. 3080-3087
    • Gobbi, G.1    Mirandola, P.2    Carubbi, C.3    Micheloni, C.4    Malinverno, C.5    Lunghi, P.6    Bonati, A.7    Vitale, M.8
  • 27
    • 45649084324 scopus 로고    scopus 로고
    • Phase 2 study of mapatumumab, a fully human agonistic monoclonal antibody which targets and activates the TRAIL receptor-1, in patients with advanced non-small cell lung cancer
    • Greco FA, et al. 2008. Phase 2 study of mapatumumab, a fully human agonistic monoclonal antibody which targets and activates the TRAIL receptor-1, in patients with advanced non-small cell lung cancer. Lung Cancer
    • (2008) Lung Cancer
    • Greco, F.A.1
  • 33
    • 33750621119 scopus 로고    scopus 로고
    • HGS-ETR1, a fully human monoclonal antibody to the tumor necrosis factor-related apoptosis-inducing ligand death receptor 1 (TRAIL-R1) in patients with advanced solid cancer: Results of a phase 1 trial
    • Hotte SJ, Hirte HW, Chen EX, Le LH, Corey A, Maclean M, Iacobucci A, Fox NL, Oza AM. 2004. HGS-ETR1, a fully human monoclonal antibody to the tumor necrosis factor-related apoptosis-inducing ligand death receptor 1 (TRAIL-R1) in patients with advanced solid cancer: Results of a phase 1 trial. J Clin Oncol 23:3052.
    • (2004) J Clin Oncol , vol.23 , pp. 3052
    • Hotte, S.J.1    Hirte, H.W.2    Chen, E.X.3    Le, L.H.4    Corey, A.5    Maclean, M.6    Iacobucci, A.7    Fox, N.L.8    Oza, A.M.9
  • 34
    • 0038622950 scopus 로고    scopus 로고
    • Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) and Fas apoptosis in Burkitt's lymphomas with loss of multiple pro-apoptotic proteins
    • Hussain A, Doucet JP, Gutierrez M, Ahmad M, Al-Hussein K, Gaidano G, Bhatia K. 2003. Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) and Fas apoptosis in Burkitt's lymphomas with loss of multiple proapoptotic proteins. Haematologica 88:167-1175. (Pubitemid 37101494)
    • (2003) Haematologica , vol.88 , Issue.2 , pp. 167-175
    • Hussain, A.1    Doucet, J.-P.2    Gutierrez, M.I.3    Ahmad, M.4    Al-Hussein, K.5    Capello, D.6    Gaidano, G.7    Bhatia, K.8
  • 38
    • 65549085701 scopus 로고    scopus 로고
    • Cullin 3-based polyubiquitination and p62-dependent aggregation of caspase-8 mediate extrinsic apoptosis signalling
    • Jin Z, Li Y, Pitti R, Lawrence D, Pham V, Lill J, Ashkenazi A. 2009. Cullin 3-based polyubiquitination and p62-dependent aggregation of caspase-8 mediate extrinsic apoptosis signalling. Cell 137:721-735.
    • (2009) Cell , vol.137 , pp. 721-735
    • Jin, Z.1    Li, Y.2    Pitti, R.3    Lawrence, D.4    Pham, V.5    Lill, J.6    Ashkenazi, A.7
  • 39
    • 0344441904 scopus 로고    scopus 로고
    • Role of the TRAIL/APO2-L death receptors in chlorambucil- And fludarabine-induced apoptosis in chronic lymphocytic leukemia
    • DOI 10.1038/sj.onc.1207004
    • Johnston JB, Kabore AF, Strutinsky J, Hu X, Paul J, Kropp D, Kuschak B, Begleiter A, Gibson SB. 2003. Role of the TRAIL/APO2-L death receptors in a chlorambucil- and fludabarine-induced apoptosis in chronic lymphocytic leukaemia. Oncogene 22:8356-8369. (Pubitemid 37485528)
    • (2003) Oncogene , vol.22 , Issue.51 , pp. 8356-8369
    • Johnston, J.B.1    Kabore, A.F.2    Strutinsky, J.3    Hu, X.4    Paul, J.T.5    Kropp, D.M.6    Kuschak, B.7    Begleiter, A.8    Gibson, S.B.9
  • 40
    • 0037832627 scopus 로고    scopus 로고
    • Cytotoxic drugs enhance the ex vivo sensitivity of malignant cells from a subset of acute myeloid leukaemia patients to apoptosis induction by tumour necrosis factor receptor-related apoptosis-inducing ligand
    • DOI 10.1046/j.1365-2141.2003.04340.x
    • Jones DT, Ganeshaguru K, Mitchell WA, Foroni L, Baker RT, Prentice HG. 2003. Cytotoxic drugs enhance the ex vivo sensitivity of malignant cells from a subset of acute myeloid leukaemia patients to apoptosis induction by tumor necrosis factor receptor-related apoptosis-inducing ligand. Br J Haematol 121:713-720. (Pubitemid 36718187)
    • (2003) British Journal of Haematology , vol.121 , Issue.5 , pp. 713-720
    • Jones, D.T.1    Ganeshaguru, K.2    Mitchell, W.A.3    Foroni, L.4    Baker, R.J.5    Prentice, H.G.6    Mehta, A.B.7    Wickremasinghe, R.G.8
  • 42
    • 35448934364 scopus 로고    scopus 로고
    • Apoptosis and anti-apoptotic mechanisms in the progression of MDS
    • Kerbany DB, Deeg J. 2007. Apoptosis and anti-apoptotic mechanisms in the progression of MDS. Exp Hematol 35:1739-1746.
    • (2007) Exp Hematol , vol.35 , pp. 1739-1746
    • Kerbany, D.B.1    Deeg, J.2
  • 44
    • 69949180337 scopus 로고    scopus 로고
    • Enhancement of TRAIL cytotoxicity by AG-490 in human ALL cells in characterized by downregulation of c-IAP-1 and c-IAP-2 through inhibition of Jak2/Stat3
    • Lanuti P, Bertagnolo V, Pierdomenico L, Bascelli A, Santavenere E, Alinari L, Capitani S, Miscia S, Marchisio M. 2009. Enhancement of TRAIL cytotoxicity by AG-490 in human ALL cells in characterized by downregulation of c-IAP-1 and c-IAP-2 through inhibition of Jak2/Stat3. Cell Res 19:1079-1089.
    • (2009) Cell Res , vol.19 , pp. 1079-1089
    • Lanuti, P.1    Bertagnolo, V.2    Pierdomenico, L.3    Bascelli, A.4    Santavenere, E.5    Alinari, L.6    Capitani, S.7    Miscia, S.8    Marchisio, M.9
  • 45
    • 85117737787 scopus 로고    scopus 로고
    • Lenalinomide treatment promotes CD154 expression on CLL cells and enhances production of antibodies by normal B cells through a PI3-kinase dependent pathway
    • in press
    • Lapalombella R, Andritsos L, Liu Q, May SE, Browning R, Pham L. in press. Lenalinomide treatment promotes CD154 expression on CLL cells and enhances production of antibodies by normal B cells through a PI3-kinase dependent pathway. Blood.
    • Blood
    • Lapalombella, R.1    Andritsos, L.2    Liu, Q.3    May, S.E.4    Browning, R.5    Pham, L.6
  • 47
    • 13844296264 scopus 로고    scopus 로고
    • Phase I study of a fully human monoclonal antibody to the tumor necrosis factor-related apoptosis-inducing ligand death receptor 4 (TRAIL-R1) in subjects with advanced solid malignancies or non-Hodgkin's lymphoma (NHL)
    • Le LH, Hirte HW, Hotte SJ, Maclean M, Iacobucci A, Corey A, Fox NL, Oza AM. 2004. Phase I study of a fully human monoclonal antibody to the tumor necrosis factor-related apoptosis-inducing ligand death receptor 4 (TRAIL-R1) in subjects with advanced solid malignancies or non-Hodgkin's lymphoma (NHL). J Clin Oncol 22:2533.
    • (2004) J Clin Oncol , vol.22 , pp. 2533
    • Le, L.H.1    Hirte, H.W.2    Hotte, S.J.3    Maclean, M.4    Iacobucci, A.5    Corey, A.6    Fox, N.L.7    Oza, A.M.8
  • 48
    • 17744364468 scopus 로고    scopus 로고
    • Somatic mutations of TRAIL-receptor 1 and TRAIL-receptor 2 genes in non-Hodgkin's lymphoma
    • Lee SH, Shin MS, Kim HS. 2001. Somatic mutations of TRAIL-receptor 1 and TRAIL-receptor 2 genes in non-Hodgkin's lymphoma. Oncogene 20:399-3403.
    • (2001) Oncogene , vol.20 , pp. 399-3403
    • Lee, S.H.1    Shin, M.S.2    Kim, H.S.3
  • 50
    • 17144392555 scopus 로고    scopus 로고
    • Absence of gene mutation in TRAIL receptor 1 (TRAIL-R1) and TRAIL receptor 2 (TRAIL-R2) in chronic myelogenous leukemia and myelodysplastic syndrome, and analysis of mRNA expressions of TRAIL and TRAIL-related genes in chronic myelogenous leukemia
    • DOI 10.1159/000083449
    • Liu LG, Tanaka H, Ito K, Ito T, Sultana TA, Kyo T, Kimura A. 2005. Absence of gene mutation in TRAIL receptor 1 (TRAIL-R1) and TRAIL receptor 2 (TRAILR2) in chronic myelogenous leukemia and myelodysplastic syndrome, and analysis of mRNA expressions of TRAIL and TRAIL-related genes in chronic myelogenous leukemia. Acta Haematol 113:113-123. (Pubitemid 40522815)
    • (2005) Acta Haematologica , vol.113 , Issue.2 , pp. 113-123
    • Liu, L.-G.1    Tanaka, H.2    Ito, K.3    Ito, T.4    Sultana, T.A.5    Kyo, T.6    Kimura, A.7
  • 51
    • 41949136647 scopus 로고    scopus 로고
    • Bortezomib blocks Bax degradation in malignant B cells during treatment with TRAIL
    • Liu FT, Agrawal SG, Gribben JG, Ye H, Du MQ, Newland AC, Jia L. 2008. Bortezomib blocks Bax degradation in malignant B cells during treatment with TRAIL. Blood 111:2797-2805.
    • (2008) Blood , vol.111 , pp. 2797-2805
    • Liu, F.T.1    Agrawal, S.G.2    Gribben, J.G.3    Ye, H.4    Du, M.Q.5    Newland, A.C.6    Jia, L.7
  • 52
    • 33947404036 scopus 로고    scopus 로고
    • Agonists of TRAIL death receptors induce myeloma cell apoptosis that is not prevented by cells of the bone marrow microenvironment
    • Locklin RM, Croucher PI, Russell RG, Edwards CM. 2007. Agonists of TRAIL death receptors induce myeloma cell apoptosis that is not prevented by cells of the bone marrow microenvironment. Leukemia 21:805-812.
    • (2007) Leukemia , vol.21 , pp. 805-812
    • Locklin, R.M.1    Croucher, P.I.2    Russell, R.G.3    Edwards, C.M.4
  • 55
    • 0037015675 scopus 로고    scopus 로고
    • Mechanisms of resistance to TRAIL-induced apoptosis in primary B cell chronic lymphocytic leukaemia
    • DOI 10.1038/sj.onc.1205853
    • MacFarlane M, Harper N, Snowden RT, Dyer M, Barnett G, Pringle H, Cohen G. 2002. Mechanisms of resistance to TRAIL-induced apoptosis in primary B cell chronic lymphocytic leukaemia. Oncogene 21:6809-6818. (Pubitemid 35221923)
    • (2002) Oncogene , vol.21 , Issue.44 , pp. 6809-6818
    • MacFarlane, M.1    Harper, N.2    Snowden, T.R.3    Dyer, M.J.S.4    Barnett, G.A.5    Pringle, J.H.6    Cohen, G.M.7
  • 57
    • 34547653954 scopus 로고    scopus 로고
    • Augmented antitumor activity against B-cell lymphoma by a combination of monoclonal antibodies targeting TRAIL-R1 and CD20
    • DOI 10.1158/1078-0432.CCR-07-0680
    • Maddipatla S, Hernandez-Llizaliturri F, Knight J, Czuczman M. 2007. Augmented antitumor activity against B-cell lymphoma by a combination of monoclonal antibodies targeting TRAIL-R1 and CD20. Clin Cancer Res 13:4556-4564. (Pubitemid 47219726)
    • (2007) Clinical Cancer Research , vol.13 , Issue.15 , pp. 4556-4564
    • Maddipatla, S.1    Hernandez-Ilizaliturri, F.J.2    Knight, J.3    Czuczman, M.S.4
  • 58
    • 13144265771 scopus 로고    scopus 로고
    • A novel receptor for Apo2L/TRAIL contains a truncated death domain
    • Marsters SA, Sheridan JP, Pitti RM. 1997. A novel receptor for Apo2L/TRAIL contains a truncated death domain. Curr Biol 7:1003-1006.
    • (1997) Curr Biol , vol.7 , pp. 1003-1006
    • Marsters, S.A.1    Sheridan, J.P.2    Pitti, R.M.3
  • 59
    • 0035761437 scopus 로고    scopus 로고
    • Loss of a novel tumor suppressor gene locus at chromosome 8p is associated with leukemic mantle cell lymphoma
    • Martinez-Climent JA, Vizcarra E, Sanchez D, Blesa D, Marugan I, Bnet I. 2001. Loss of a novel tumor suppressor gene locus at chromosome 8p is associated with leukemic mantle cell lymphoma. Blood 98:3479-3482.
    • (2001) Blood , vol.98 , pp. 3479-3482
    • Martinez-Climent, J.A.1    Vizcarra, E.2    Sanchez, D.3    Blesa, D.4    Marugan, I.5    Bnet, I.6
  • 61
    • 13744263743 scopus 로고    scopus 로고
    • Resistance to Apo2 ligand (Apo2L)/tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-mediated apoptosis and constitutive expression of Apo2L/TRAIL in human T-cell leukemia virus type 1-infected T-cell lines
    • DOI 10.1128/JVI.79.3.1367-1378.2005
    • Matsuda T, Almasan A, Tomita M, Uchihara J, Masuda M, Ohshiro K, Takasu N, Yagita H, Ohta T, Mori N. 2005. Resistance to Apo2 Ligand (Apo2L9/Tumor Necrosis Factor Related Apoptosis-inducing ligand (TRAIL)-mediated apoptosis and constitutive expression of Apo2L/TRAIL in human T-cell leukaemia virus type 1-infected T-cell lines. J Virol 79:1367-1378. (Pubitemid 40459084)
    • (2005) Journal of Virology , vol.79 , Issue.3 , pp. 1367-1378
    • Matsuda, T.1    Almasan, A.2    Tomita, M.3    Uchihara, J.-N.4    Masuda, M.5    Ohshiro, K.6    Takasu, N.7    Yagita, H.8    Ohta, T.9    Mori, N.10
  • 63
  • 64
    • 0030999555 scopus 로고    scopus 로고
    • A breakpoint map of recurrent chromosomal rearrangements in human neoplasia
    • Mitelman F, Mertens F, Johansson B. 1997. A breakpoint map of recurrent chromosomal rearrangements in human neoplasia. Nat Genet 15(Spec No.): 417-474.
    • (1997) Nat Genet , vol.15 , Issue.SPEC NO , pp. 417-474
    • Mitelman, F.1    Mertens, F.2    Johansson, B.3
  • 66
    • 0037085796 scopus 로고    scopus 로고
    • Intracellular regulation of tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis in human multiple myeloma cells
    • DOI 10.1182/blood.V99.6.2162
    • Mitsiades N, Mitsiades CS, Poulaki V, Anderson KC, Treon SP. 2002. Intracellular regulation of tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis in human multiple myeloma cells. Blood 99:2162-2171. (Pubitemid 34525502)
    • (2002) Blood , vol.99 , Issue.6 , pp. 2162-2171
    • Mitsiades, N.1    Mitsiades, C.S.2    Poulaki, V.3    Anderson, K.C.4    Treon, S.P.5
  • 67
    • 0029904295 scopus 로고    scopus 로고
    • DNA copy number changes in diffuse large B-cell lymphoma-comparative genomic hybridization study
    • Monni O, Joensuu H, Franssila K, Knuutila S. 1996. DNA copy number changes in diffuse B-cell lymphoma: Comparative genomic hybridization study. Blood 87:5269-5278. (Pubitemid 26189870)
    • (1996) Blood , vol.87 , Issue.12 , pp. 5269-5278
    • Monni, O.1    Joensuu, H.2    Franssila, K.3    Knuutila, S.4
  • 68
    • 0038007343 scopus 로고    scopus 로고
    • Regulation of tumour necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced apoptosis in Burkitt's lymphoma cell lines
    • DOI 10.1046/j.1365-2141.2003.04424.x
    • Mouzakiti A, Packham G. 2003. Regulation of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced apoptosis in Burkitt's lymphoma cell lines. Br J Haematol 122:61-69. (Pubitemid 36819339)
    • (2003) British Journal of Haematology , vol.122 , Issue.1 , pp. 61-69
    • Mouzakiti, A.1    Packham, G.2
  • 72
    • 0035126944 scopus 로고    scopus 로고
    • Cotreatment with STI-571 enhances tumor necrosis factor a-related apoptosis-inducing ligand (TRAIL or Apo-2L)-induced apoptosis of Bcr-Abl-positive human acute leukemia cells
    • Nimmanapalli R, Porosnicu M, Nguyen D, Worthington E, O'Bryan E, Perkins C, Bhalla K. 2001. Cotreatment with STI-571 enhances tumor necrosis factor a-related apoptosis-inducing ligand (TRAIL or Apo-2L)-induced apoptosis of Bcr-Abl-positive human acute leukemia cells. Clin Cancer Res 7:350-357. (Pubitemid 32183039)
    • (2001) Clinical Cancer Research , vol.7 , Issue.2 , pp. 350-357
    • Nimmanapalli, R.1    Porosnicu, M.2    Nguyen, D.3    Worthington, E.4    O'Bryan, E.5    Perkins, C.6    Bhalla, K.7
  • 73
    • 68349090436 scopus 로고    scopus 로고
    • Synergistic induction of apoptosis in primary B-CLL cells after treatment with recombinant tumor necrosis factor-related apoptosis-inducing ligand and histone deacetylase inhibitors
    • Norian LA, Kucaba TA, Earel JK, Knutson T, Van Oosten RL, Griffith TS. 2009. Synergistic induction of apoptosis in primary B-CLL cells after treatment with recombinant tumor necrosis factor-related apoptosis-inducing ligand and histone deacetylase inhibitors. J Oncol 2009:408038.
    • (2009) J Oncol , vol.2009 , pp. 408038
    • Norian, L.A.1    Kucaba, T.A.2    Earel, J.K.3    Knutson, T.4    Van Oosten, R.L.5    Griffith, T.S.6
  • 74
    • 70449923187 scopus 로고    scopus 로고
    • The effect of microenvironmental CD40 signals on TRAIL- and drug-induced apoptosis in follicular lymphoma cells
    • Nuutinen U, Ropponen A, Eeva J, Eray M, Pellinen R, Wahlfors J, Pelkonen J. The effect of microenvironmental CD40 signals on TRAIL- and drug-induced apoptosis in follicular lymphoma cells. Scand J Immunol 2009. 70:565-573.
    • (2009) Scand J Immunol , vol.70 , pp. 565-573
    • Nuutinen, U.1    Ropponen, A.2    Eeva, J.3    Eray, M.4    Pellinen, R.5    Wahlfors, J.6    Pelkonen, J.7
  • 75
    • 33645893189 scopus 로고    scopus 로고
    • Human T-cell leukaemia virus type-I oncoprotein Tax inhibits Fas-mediated apoptosis by inducing cellular FLIP through activation of NF-kB
    • Okamoto K, Fujisawa JI, Reth M, Yonehora S. 2006. Human T-cell leukaemia virus type-I oncoprotein Tax inhibits Fas-mediated apoptosis by inducing cellular FLIP through activation of NF-kB. Genes Cells 11:177-191.
    • (2006) Genes Cells , vol.11 , pp. 177-191
    • Okamoto, K.1    Fujisawa, J.I.2    Reth, M.3    Yonehora, S.4
  • 77
    • 65649122622 scopus 로고    scopus 로고
    • Sensitization of imatinib-resistant CML cells to TRAIL-induced apoptosis is mediated through down-regulation of Bcr-Abl as well as c-FLIP
    • Park SJ, Kim MJ, Kim HB, Kang CD, Kim SH. 2009. Sensitization of imatinib-resistant CML cells to TRAIL-induced apoptosis is mediated through down-regulation of Bcr-Abl as well as c-FLIP. Biochem J 420:73-7381.
    • (2009) Biochem J , vol.420 , pp. 73-7381
    • Park, S.J.1    Kim, M.J.2    Kim, H.B.3    Kang, C.D.4    Kim, S.H.5
  • 78
    • 67349264883 scopus 로고    scopus 로고
    • Cotreatment with apicidin overcomes TRAIL resistance via inhibition of Bcr-Abl signaling pathway in K562 leukemia cells
    • Park SJ, Kim MJ, Kim HB, Sohn HY, Bae JH, Kang CD, Kim SH. 2009. Cotreatment with apicidin overcomes TRAIL resistance via inhibition of Bcr-Abl signaling pathway in K562 leukemia cells. Exp Cell Res 315:1809-1818.
    • (2009) Exp Cell Res , vol.315 , pp. 1809-1818
    • Park, S.J.1    Kim, M.J.2    Kim, H.B.3    Sohn, H.Y.4    Bae, J.H.5    Kang, C.D.6    Kim, S.H.7
  • 79
    • 33947174342 scopus 로고    scopus 로고
    • Sensitivity and resistance of human cancer cells to TRAIL: Mechanisms and therapeutical perspectives
    • Pasquini L, Petrucci E, Riccioni R, Petronelli A, Testa U. 2006. Sensitivity and resistance of human cancer cells to TRAIL: Mechanisms and therapeutical perspectives. Cancer Therapy 4:47-72.
    • (2006) Cancer Therapy , vol.4 , pp. 47-72
    • Pasquini, L.1    Petrucci, E.2    Riccioni, R.3    Petronelli, A.4    Testa, U.5
  • 81
    • 40749116017 scopus 로고    scopus 로고
    • Bone marrow stroma confers resistance to Apo2Ligand/TRAIL in multiple myeloma in part by regulating c-FLIP
    • Perez LE, Parquet N, Shain K, Nimmanapalli R, Alsinja M, Anasetti C, Dalton W. 2008. Bone marrow stroma confers resistance to Apo2Ligand/TRAIL in multiple myeloma in part by regulating c-FLIP. J Immunol 180:1545-1555.
    • (2008) J Immunol , vol.180 , pp. 1545-1555
    • Perez, L.E.1    Parquet, N.2    Shain, K.3    Nimmanapalli, R.4    Alsinja, M.5    Anasetti, C.6    Dalton, W.7
  • 82
    • 76249085456 scopus 로고    scopus 로고
    • Bortezomib restores stroma-mediated APO2L/TRAIL apoptosis resistance in multiple myeloma
    • Perez LE, Parquet N, Meads M, Anasetti C, Dalton W. 2010. Bortezomib restores stroma-mediated APO2L/TRAIL apoptosis resistance in multiple myeloma. Eur J Haematol 84:212-222.
    • (2010) Eur J Haematol , vol.84 , pp. 212-222
    • Perez, L.E.1    Parquet, N.2    Meads, M.3    Anasetti, C.4    Dalton, W.5
  • 84
    • 0034146471 scopus 로고    scopus 로고
    • Cultivated HRS cells are resistant to CD95L-mediated apoptosis despite expression of wild-type CD95
    • Re D, Hoffmaqnn A, Wolf J, Diehl V, Staratsche K, Jox A. 2000. Cultivated HRS cells are resistant to CD95L-mediated apoptosis despite expression of wild-type CD95. Exp Hematol 28:348-360.
    • (2000) Exp Hematol , vol.28 , pp. 348-360
    • Re, D.1    Hoffmaqnn, A.2    Wolf, J.3    Diehl, V.4    Staratsche, K.5    Jox, A.6
  • 87
    • 33846476267 scopus 로고    scopus 로고
    • Selective inhibition of IkB kinase sensitizes mantle cell lymphoma B cells to TRAIL by decreasing cellular FLIP level
    • Roué G, Perez-Galàn P, Lòpez-Guerra M, Villamour N, Campo E, Colomer D. 2007. Selective inhibition of IkB kinase sensitizes mantle cell lymphoma B cells to TRAIL by decreasing cellular FLIP level. J Immunol 178:1923-1930. (Pubitemid 46154665)
    • (2007) Journal of Immunology , vol.178 , Issue.3 , pp. 1923-1930
    • Roue, G.1    Perez-Galan, P.2    Lopez-Guerra, M.3    Villamor, N.4    Campo, E.5    Colomer, D.6
  • 93
    • 0036786215 scopus 로고    scopus 로고
    • Tumor necrosis factor-related apoptosis-inducing ligand induces monocytic maturation of leukemic and normal myeloid precursors through a caspase-dependent pathway
    • Secchiero P, Gonelli A, Miarnadola P, Melloni E, Zamai I, Celeghini C. 2002. Tumor necrosis factor-related apoptosis-inducing ligand induces monocytic maturation of leukemic and normal myeloid precursors through a caspase-dependent pathway. Blood 100:2421-2429.
    • (2002) Blood , vol.100 , pp. 2421-2429
    • Secchiero, P.1    Gonelli, A.2    Miarnadola, P.3    Melloni, E.4    Zamai, I.5    Celeghini, C.6
  • 95
    • 33646574651 scopus 로고    scopus 로고
    • Functional integrity of the p53-mediated apoptotic pathway induced by the nongenotoxic agent nutlin-3 in B-cell chronic lymphocytic leukemia (B-CLL)
    • DOI 10.1182/blood-2005-11-4465
    • Secchiero P, Barbarotto E, Tiribelli M, Zerbinati C, di Iasio MG, Gonelli A, Cavazzini F, Carupioni D, Fanin R, Cuneo A, Zauli G. 2006. Functional integrity of the p53-mediated apoptotic pathway induced by the nongenotoxic agent nutilin-3 in B-cell chronic lymphocytic leukemia (B-CLL). Blood 107:4122-4129. (Pubitemid 43726822)
    • (2006) Blood , vol.107 , Issue.10 , pp. 4122-4129
    • Secchiero, P.1    Barbarotto, E.2    Tiribelli, M.3    Zerbinati, C.4    Di Iasio, M.G.5    Gonelli, A.6    Cavazzini, F.7    Campioni, D.8    Fanin, R.9    Cuneo, A.10    Zauli, G.11
  • 96
    • 0037374460 scopus 로고    scopus 로고
    • Osteoprotegerin is a soluble decoy receptor for tumor necrosis factor-related apoptosis-inducing ligand/Apo2 ligand and can function as a paracrine survival factor for human myeloma cells
    • Shipman CM, Croucher PJ. 2003. Osteoprotegerin is a soluble decoy receptor for tumor necrosis factor-related apoptosis-inducing ligand/Apo2 ligand and can function as a paracrine survival factor for human myeloma cells. Cancer Res 63:912-916.
    • (2003) Cancer Res , vol.63 , pp. 912-916
    • Shipman, C.M.1    Croucher, P.J.2
  • 97
    • 45749137688 scopus 로고    scopus 로고
    • A phase Ib study to assess the safety of lexatumumab, a human monoclonal antibody that activates TRAIL-R2, in combination with gemcitabine, pemetrexed, doxorubicin or FOLFIRI
    • Sikic BI, Wakelee HA, Von Mehren M, Lewis N, Calvert AH, Plummer ER, Fox L, Howard T, Jones FS, Burris HA. 2007. A phase Ib study to assess the safety of lexatumumab, a human monoclonal antibody that activates TRAIL-R2, in combination with gemcitabine, pemetrexed, doxorubicin or FOLFIRI. J Clin Oncol 25:14006.
    • (2007) J Clin Oncol , vol.25 , pp. 14006
    • Sikic, B.I.1    Wakelee, H.A.2    Von Mehren, M.3    Lewis, N.4    Calvert, A.H.5    Plummer, E.R.6    Fox, L.7    Howard, T.8    Jones, F.S.9    Burris, H.A.10
  • 98
    • 34848912052 scopus 로고    scopus 로고
    • Bortezomib sensitizes non-Hodgkin's lymphoma cells to apoptosis induced by antibodies to tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) receptors TRAIL-R1 and TRAIL-R2
    • Smith MR, Jin F, Joshi I. 2007. Bortezomib sensitizes non-Hodgkin's lymphoma cells to apoptosis induced by antibodies to tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) receptors TRAIL-R1 and TRAIL-R2. Clin Cancer Res 13(Suppl 18):55285-55345.
    • (2007) Clin Cancer Res , vol.13 , Issue.SUPPL. 18 , pp. 55285-55345
    • Smith, M.R.1    Jin, F.2    Joshi, I.3
  • 99
    • 85117738658 scopus 로고    scopus 로고
    • TRAIL-induced apoptosis of authentic myeloma cells does not correlate with the procaspase-8/cFLIP ratio
    • Spencer A, Yeh SL, Koutrevelis K, Bautch-Brown C. 2002. TRAIL-induced apoptosis of authentic myeloma cells does not correlate with the procaspase-8/cFLIP ratio. Blood 100:3050-3051.
    • (2002) Blood , vol.100 , pp. 3050-3051
    • Spencer, A.1    Yeh, S.L.2    Koutrevelis, K.3    Bautch-Brown, C.4
  • 101
    • 33644873448 scopus 로고    scopus 로고
    • Potential mechanism of resistance to TRAIL-induced apoptosis in Burkitt's lymphoma
    • Tafuku S, Matsuda T, Kawakami H, Tomita M, Yagita H, Mori N. 2006. Potential mechanism of resistance to TRAIL-induced apoptosis in Burkitt's lymphoma. Eur J Haematol 76:64-74.
    • (2006) Eur J Haematol , vol.76 , pp. 64-74
    • Tafuku, S.1    Matsuda, T.2    Kawakami, H.3    Tomita, M.4    Yagita, H.5    Mori, N.6
  • 103
    • 2342623331 scopus 로고    scopus 로고
    • IFNα-stimulated neutrophils and monocytes release a soluble form of TNF-related apoptosis-inducing ligand (TRAIL/Apo-2 ligand) displaying apoptotic activity on leukemic cells
    • DOI 10.1182/blood-2003-08-2806
    • Tecchio C, Huber V, Scapini P, Calzetti F, Margotto D, Todeschini G, Pilla L, Martinelli G, Pizzolo G, Rivoltini L, Cassatelle M. 2004. IFNα-stimulated neutrophils and monocytes release a soluble form of TNF-related apoptosis-inducing ligand (TRAIL/Apo-2 ligand) displaying apoptotic activity on leukemic cells. Blood 103:3837-3844. (Pubitemid 38596303)
    • (2004) Blood , vol.103 , Issue.10 , pp. 3837-3844
    • Tecchio, C.1    Huber, V.2    Scapini, P.3    Calzetti, F.4    Margotto, D.5    Todeschini, G.6    Pilla, L.7    Martinelli, G.8    Pizzolo, G.9    Rivoltini, L.10    Cassatella, M.A.11
  • 104
    • 34248187996 scopus 로고    scopus 로고
    • Phase I pharmacokinetic and biologic correlative study of mapatumumab, a fully human monoclonal antibody with agonist activity to tumor necrosis factor-related apoptosis-inducing ligand receptor-1
    • DOI 10.1200/JCO.2006.08.8898
    • Tolcher AW, Mita M, Meropol NJ, von Mehren M, Patnaik A, Padavic K, Hill M, Mays T, McCoy T, Fox NL, Halpern W, Corey A, Cohen RB. 2007. Phase I pharmacokinetic and biologic correlative study of mapatumumab, a fully human monoclonal antibody with agonist activity to tumor necrosis factor-related apoptosis-inducing ligand receptor-1. J Clin Oncol 25:1390-1395. (Pubitemid 46706887)
    • (2007) Journal of Clinical Oncology , vol.25 , Issue.11 , pp. 1390-1395
    • Tolcher, A.W.1    Mita, M.2    Meropol, N.J.3    Von Mehren, M.4    Patnaik, A.5    Padavic, K.6    Hill, M.7    Mays, T.8    McCoy, T.9    Fox, N.L.10    Halpern, W.11    Corey, A.12    Cohen, R.B.13
  • 106
    • 0042744782 scopus 로고    scopus 로고
    • Mycosis fungoides shows concurrent deregulation of multiple genes involved in the TNF signaling pathway: An expression profile study
    • DOI 10.1182/blood-2002-11-3574
    • Tracey L, Villuendas R, Dotor AM, Spiteri I, Ortiz P, Garcia J, Peralto JL, Lawler M, Piris M. 2003. Mycosis fungoides shows concurrent deregulation of multiple genes involved in the TNF signalling pathway: An expression profile study. Blood 102:1042-1050. (Pubitemid 36917802)
    • (2003) Blood , vol.102 , Issue.3 , pp. 1042-1050
    • Tracey, L.1    Villuendas, R.2    Dotor, A.M.3    Spiteri, I.4    Ortiz, P.5    Garcia, J.F.6    Rodriguez Peralto, J.L.7    Lawler, M.8    Piris, M.A.9
  • 107
    • 49049086995 scopus 로고    scopus 로고
    • CD40 ligand protects from TRAIL-induced apoptosis in follicular lymphomas through NF-κB activation and upregulation of c-FLIP and Bcl-XL
    • Travert M, Ame-Thomas P, Pangault C, Morizot A, Micheau O, Semana G, Lamy T, Fest T, Tarte K, Guilaudeux T. 2008. CD40 ligand protects from TRAIL-induced apoptosis in follicular lymphomas through NF-κB activation and upregulation of c-FLIP and Bcl-XL. J Immunol 181:1001-1011.
    • (2008) J Immunol , vol.181 , pp. 1001-1011
    • Travert, M.1    Ame-Thomas, P.2    Pangault, C.3    Morizot, A.4    Micheau, O.5    Semana, G.6    Lamy, T.7    Fest, T.8    Tarte, K.9    Guilaudeux, T.10
  • 108
    • 8644229153 scopus 로고    scopus 로고
    • TRAIL induction by radiation in lymphoma patients
    • DOI 10.1081/CNV-200026397
    • Unnithan J, Macklis RM. 2004. TRAIL induction by radiation in lymphoma patients. Cancer Invest 22:522-525. (Pubitemid 39506872)
    • (2004) Cancer Investigation , vol.22 , Issue.4 , pp. 522-525
    • Unnithan, J.1    Macklis, R.M.2
  • 112
    • 0034551746 scopus 로고    scopus 로고
    • Antileukemic drugs increase death receptor 5 levels and enhance Apo-2L-induced apoptosis of acute human leukaemia cells
    • Wen J, Ramadevi N, Nguyen D, Perkins C, Worthington E, Bhalia K. 2000. Antileukemic drugs increase death receptor 5 levels and enhance Apo-2L-induced apoptosis of acute human leukaemia cells. Blood 96:3900-3906.
    • (2000) Blood , vol.96 , pp. 3900-3906
    • Wen, J.1    Ramadevi, N.2    Nguyen, D.3    Perkins, C.4    Worthington, E.5    Bhalia, K.6
  • 113
    • 33748056488 scopus 로고    scopus 로고
    • TRAIL enhances efficacy of radiotherapy in a p53 mutant, Bcl-2 overexpressing lymphoid malignancy
    • DOI 10.1016/j.radonc.2006.07.030, PII S0167814006003082, Papers from ICTR 2006. International Conference on Transtational Research and Pre-Clinical Stratigies in Rediation Oncology
    • Wissink EH, Verbrugge I, Vink SR, Schader U, Walczak H, Borst J, Verheij M. 2006. TRAIL enhances efficacy of radiotherapy in a p53 mutant, Bcl-2 overexpressing lymphoid malignancy. Radiother Oncol 80:214-222. (Pubitemid 44301543)
    • (2006) Radiotherapy and Oncology , vol.80 , Issue.2 , pp. 214-222
    • Wissink, E.H.J.1    Verbrugge, I.2    Vink, S.R.3    Schader, M.B.4    Schaefer, U.5    Walczak, H.6    Borst, J.7    Verheij, M.8
  • 114
    • 0034989624 scopus 로고    scopus 로고
    • In vitro susceptibility to TRAIL-induced apoptosis of acute leukemia cells in the context of TRAIL receptor gene expression and constitutive NF-kappa B activity
    • Wuchter C, Krappmann D, Cai Z, Ruppert V, Scheiderreit C, Dorken B, Ludwig WD, Karawajew L. 2001. In vitro susceptibility to TRAIL-induced apoptosis of acute leukemia cells in the context of TRAIL receptor gene expression and constitutive NF-kappa B activity. Leukemia 15:921-928.
    • (2001) Leukemia , vol.15 , pp. 921-928
    • Wuchter, C.1    Krappmann, D.2    Cai, Z.3    Ruppert, V.4    Scheiderreit, C.5    Dorken, B.6    Ludwig, W.D.7    Karawajew, L.8
  • 115
    • 37149035841 scopus 로고    scopus 로고
    • A phase IB safety and pharmacokinetic (PK) study of recombinant human Apo2L/TRAIL in combination with rituximab in patients with low-grade non-Hodgkin lymphoma
    • Yee L, Fanale M, Dimick K, Calvert S, Robins C, Ing J, Ling J, Novotny W, Ashkenazi A, Burris H. 2007. A phase IB safety and pharmacokinetic (PK) study of recombinant human Apo2L/TRAIL in combination with rituximab in patients with low-grade non-Hodgkin lymphoma. J Clin Oncol 25:8078.
    • (2007) J Clin Oncol , vol.25 , pp. 8078
    • Yee, L.1    Fanale, M.2    Dimick, K.3    Calvert, S.4    Robins, C.5    Ing, J.6    Ling, J.7    Novotny, W.8    Ashkenazi, A.9    Burris, H.10
  • 117
    • 33646390886 scopus 로고    scopus 로고
    • Results of a phase 2 trial of HGS-ETR1 (agonistic human monoclonal antibody to TRAIL receptor 1) in subjects with relapsed/refractory non-Hodgkin's lymphoma (NHL)
    • Abstract 489
    • Younes A, et al. 2005. Results of a phase 2 trial of HGS-ETR1 (agonistic human monoclonal antibody to TRAIL receptor 1) in subjects with relapsed/refractory non-Hodgkin's lymphoma (NHL). Blood 106: Abstract 489.
    • (2005) Blood , vol.106
    • Younes, A.1
  • 119
    • 0035892123 scopus 로고    scopus 로고
    • Expression of tumor necrosis factor-related apoptosis-inducing ligand, Apo2L, and its receptors in myelodysplastic syndrome: Effects on in vitro hemopoiesis
    • Zang Y, Goodwin R, Loken M, Bryant E, Deeg J. 2001. Expression of tumor necrosis factor-related apoptosis-inducing ligand, Apo2L, and its receptors in myelodysplastic syndrome: Effects on in vitro hemopoiesis. Blood 98:3058-3065.
    • (2001) Blood , vol.98 , pp. 3058-3065
    • Zang, Y.1    Goodwin, R.2    Loken, M.3    Bryant, E.4    Deeg, J.5
  • 120
    • 0035264546 scopus 로고    scopus 로고
    • Resistance to Fas-mediated apoptosis of human T-cell lines expressing human T-lymphotropic virus type-2 (HTLV-2) tax protein
    • DOI 10.1006/viro.2000.0765
    • Zehender G, Varchetta S, De Maddalena C. 2001. Resistance to Fas-mediated apoptosis of human T-cell lines expressing human T-lymphotropic virus type-2 (HTLV-2) Tax protein. Virology 281:43-50. (Pubitemid 32911524)
    • (2001) Virology , vol.281 , Issue.1 , pp. 43-50
    • Zehender, G.1    Varchetta, S.2    De Maddalena, C.3    Colasante, C.4    Riva, A.5    Meroni, L.6    Moroni, M.7    Galli, M.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.