-
1
-
-
0025753852
-
The molecular pathology of alzheimer's disease
-
Selkoe DJ (1991) The molecular pathology of Alzheimer's disease. Neuron 6, 487-498
-
(1991)
Neuron
, vol.6
, pp. 487-498
-
-
Selkoe, D.J.1
-
2
-
-
0025899041
-
Amyloid deposition as the central event in the aetiology of Alzheimer's disease
-
Hardy J, Allsop D (1991) Amyloid deposition as the central event in the aetiology of Alzheimer's disease. Trends Pharmacol Sci 12, 383-388
-
(1991)
Trends Pharmacol Sci
, vol.12
, pp. 383-388
-
-
Hardy, J.1
Allsop, D.2
-
3
-
-
0022531202
-
Seizures and myoclonus in patients with Alzheimer's disease
-
Hauser WA, Morris ML, Heston LL, Anderson VE (1986) Seizures and myoclonus in patients with Alzheimer's disease. Neurology 36, 1226-1230 (Pubitemid 16047002)
-
(1986)
Neurology
, vol.36
, Issue.9
, pp. 1226-1230
-
-
Hauser, W.A.1
Morris, M.L.2
Heston, L.L.3
Anderson, V.E.4
-
4
-
-
0035877756
-
Early-onset Amyloid Deposition and Cognitive Deficits in Transgenic Mice Expressing a Double Mutant Form of Amyloid Precursor Protein 695
-
DOI 10.1074/jbc.M100710200
-
ChishtiMA,Yang DS, Janus C, Phinney AL, Horne P, Pearson J, Strome R, Zuker N, Loukides J, French J, Turner S, Lozza G, Grilli M, Kunicki S, Morissette C, Paquette J, Gervais F, Bergeron C, Fraser PE, Carlson GA, George-Hyslop PS, Westaway D (2001) Early-onset amyloid deposition and cognitive deficits in transgenic mice expressing a double mutant form of amyloid precursor protein 695. J Biol Chem 276, 21562-21570 (Pubitemid 37413154)
-
(2001)
Journal of Biological Chemistry
, vol.276
, Issue.24
, pp. 21562-21570
-
-
Chishti, M.A.1
Yang, D.-S.2
Janus, C.3
Phinney, A.L.4
Horne, P.5
Pearson, J.6
Strome, R.7
Zuker, N.8
Loukides, J.9
French, J.10
Turner, S.11
Lozza, G.12
Grilli, M.13
Kunicki, S.14
Morissette, C.15
Paquette, J.16
Gervais, F.17
Bergeron, C.18
Fraser, P.E.19
Carlson, G.A.20
St. George-Hyslop, P.21
Westawaya, D.22
more..
-
5
-
-
4344564473
-
Increased seizure threshold and severity in young transgenic CRND8 mice
-
DOI 10.1016/j.neulet.2004.05.107, PII S0304394004007177
-
Del Vecchio RA, Gold LH, Novick SJ, Wong G, Hyde LA (2004) Increased seizure threshold and severity in young transgenic CRND8 mice. Neurosci Lett 367, 164-167 (Pubitemid 39141218)
-
(2004)
Neuroscience Letters
, vol.367
, Issue.2
, pp. 164-167
-
-
Del Vecchio, R.A.1
Gold, L.H.2
Novick, S.J.3
Wong, G.4
Hyde, L.A.5
-
6
-
-
84883841879
-
Object recognition memory and BDNF expression are reduced in young TgCRND8 mice
-
Francis BM, Kim J, Barakat ME, Fraenkl S, Yucel YH, Peng S, Michalski B, Fahnestock M, McLaurin J, Mount HT (2010) Object recognition memory and BDNF expression are reduced in young TgCRND8 mice. Neurobiol Aging 33, 555-563
-
(2010)
Neurobiol Aging
, vol.33
, pp. 555-563
-
-
Francis, B.M.1
Kim, J.2
Barakat, M.E.3
Fraenkl, S.4
Yucel, Y.H.5
Peng, S.6
Michalski, B.7
Fahnestock, M.8
McLaurin, J.9
Mount, H.T.10
-
7
-
-
3042567711
-
Inflammation occurs early during the Aβ deposition process in TgCRND8 mice
-
DOI 10.1016/j.neurobiolaging.2003.08.008, PII S0197458003001945
-
Dudal S, Krzywkowski P, Paquette J, Morissette C, Lacombe D, Tremblay P, Gervais F (2004) Inflammation occurs early during the Abeta deposition process in TgCRND8 mice. Neurobiol Aging 25, 861-871 (Pubitemid 38813166)
-
(2004)
Neurobiology of Aging
, vol.25
, Issue.7
, pp. 861-871
-
-
Dudal, S.1
Krzywkowski, P.2
Paquette, J.3
Morissette, C.4
Lacombe, D.5
Tremblay, P.6
Gervais, F.7
-
8
-
-
84866751526
-
Tnfalpha in synaptic function: Switching gears
-
Santello M, Volterra A (2012) TNFalpha in synaptic function: Switching gears. Trends Neurosci 35, 638-647
-
(2012)
Trends Neurosci
, vol.35
, pp. 638-647
-
-
Santello, M.1
Volterra, A.2
-
9
-
-
80155156965
-
Early molecular and synaptic dysfunctions in the prodromal stages of Alzheimer's disease: Focus on TNF-and IL-1
-
Cavanagh C, Colby-Milley J, Farso M, Krantic S, Quirion R (2011) Early molecular and synaptic dysfunctions in the prodromal stages of Alzheimer's disease: Focus on TNF-And IL-1-. Future Neurol 6, 757-769
-
(2011)
Future Neurol
, vol.6
, pp. 757-769
-
-
Cavanagh, C.1
Colby-Milley, J.2
Farso, M.3
Krantic, S.4
Quirion, R.5
-
10
-
-
84859390704
-
HippocampalGABAergic neurons are susceptible to amyloid-beta toxicity in vitro and are decreased in number in the Alzheimer's disease TgCRND8 mouse model
-
Krantic S, Isorce N, Mechawar N, Davoli MA, Vignault E, Albuquerque M, Chabot JG, Moyse E, Chauvin JP, Aubert I, McLaurin J, Quirion R (2012) HippocampalGABAergic neurons are susceptible to amyloid-beta toxicity in vitro and are decreased in number in the Alzheimer's disease TgCRND8 mouse model. J Alzheimers Dis 29, 293-308
-
(2012)
J Alzheimers Dis
, vol.29
, pp. 293-308
-
-
Krantic, S.1
Isorce, N.2
Mechawar, N.3
Davoli, M.A.4
Vignault, E.5
Albuquerque, M.6
Chabot, J.G.7
Moyse, E.8
Chauvin, J.P.9
Aubert, I.10
McLaurin, J.11
Quirion, R.12
-
11
-
-
0028953529
-
Activation of microglial cells by beta-Amyloid protein and interferon-gamma
-
Meda L, Cassatella MA, Szendrei GI, Otvos L, Jr., Baron P, Villalba M, Ferrari D, Rossi F (1995) Activation of microglial cells by beta-Amyloid protein and interferon-gamma. Nature 374, 647-650
-
(1995)
Nature
, vol.374
, pp. 647-650
-
-
Meda, L.1
Cassatella, M.A.2
Szendrei, G.I.3
Otvos Jr., L.4
Baron, P.5
Villalba, M.6
Ferrari, D.7
Rossi, F.8
-
12
-
-
79952563494
-
Low-n oligomers as therapeutic targets of alzheimer's disease
-
Ono K, Yamada M (2011) Low-n oligomers as therapeutic targets of Alzheimer's disease. J Neurochem 117, 19-28
-
(2011)
J Neurochem
, vol.117
, pp. 19-28
-
-
Ono, K.1
Yamada, M.2
-
13
-
-
77952515576
-
An overview of APP processing enzymes and products
-
Chow VW, Mattson MP,Wong PC, GleichmannM(2010) An overview of APP processing enzymes and products. Neuromolecular Med 12, 1-12
-
(2010)
Neuromolecular Med
, vol.12
, pp. 1-12
-
-
Chow, V.W.1
Mattson, M.P.2
Wong, P.C.3
Gleichmann, M.4
-
14
-
-
62249094525
-
Inhibition of soluble tnf signaling in a mouse model of alzheimer's disease prevents pre-plaque amyloid-Associated neuropathology
-
McAlpine FE, Lee JK, Harms AS, Ruhn KA, Blurton-Jones M, Hong J, Das P, Golde TE, LaFerla FM, Oddo S, Blesch A, Tansey MG (2009) Inhibition of soluble TNF signaling in a mouse model of Alzheimer's disease prevents pre-plaque amyloid-Associated neuropathology. Neurobiol Dis 34, 163-177
-
(2009)
Neurobiol Dis
, vol.34
, pp. 163-177
-
-
McAlpine, F.E.1
Lee, J.K.2
Harms, A.S.3
Ruhn, K.A.4
Blurton-Jones, M.5
Hong, J.6
Das, P.7
Golde, T.E.8
LaFerla, F.M.9
Oddo, S.10
Blesch, A.11
Tansey, M.G.12
-
16
-
-
19744380563
-
Neuroscience: Resting microglial cells are highly dynamic surveillants of brain parenchyma in vivo
-
DOI 10.1126/science.1110647
-
Nimmerjahn A, Kirchhoff F, Helmchen F (2005) Resting microglial cells are highly dynamic surveillants of brain parenchyma in vivo. Science 308, 1314-1318 (Pubitemid 40746128)
-
(2005)
Science
, vol.308
, Issue.5726
, pp. 1314-1318
-
-
Nimmerjahn, A.1
Kirchhoff, F.2
Helmchen, F.3
-
17
-
-
0033044951
-
Reactive microgliosis
-
DOI 10.1016/S0301-0082(98)00069-0, PII S0301008298000690
-
Streit WJ,Walter SA, Pennell NA (1999) Reactive microgliosis. Prog Neurobiol 57, 563-581 (Pubitemid 29148415)
-
(1999)
Progress in Neurobiology
, vol.57
, Issue.6
, pp. 563-581
-
-
Streit, W.J.1
Walter, S.A.2
Pennell, N.A.3
-
18
-
-
79955605102
-
Physiology of microglia
-
Kettenmann H, Hanisch UK, Noda M, Verkhratsky A (2011) Physiology of microglia. Physiol Rev 91, 461-553
-
(2011)
Physiol Rev
, vol.91
, pp. 461-553
-
-
Kettenmann, H.1
Hanisch, U.K.2
Noda, M.3
Verkhratsky, A.4
-
19
-
-
84872903768
-
Quantitating the subtleties of microglial morphology with fractal analysis
-
Karperien A, Ahammer H, Jelinek HF (2013) Quantitating the subtleties of microglial morphology with fractal analysis. Front Cell Neurosci 7, 3
-
(2013)
Front Cell Neurosci
, vol.7
, pp. 3
-
-
Karperien, A.1
Ahammer, H.2
Jelinek, H.F.3
-
20
-
-
67349181734
-
PK11195 labels activated microglia in Alzheimer's disease and in vivo in a mouse model using PET
-
Venneti S, Lopresti BJ, Wang G, Hamilton RL, Mathis CA, Klunk WE, Apte UM,Wiley CA (2009) PK11195 labels activated microglia in Alzheimer's disease and in vivo in a mouse model using PET. Neurobiol Aging 30, 1217-1226
-
(2009)
Neurobiol Aging
, vol.30
, pp. 1217-1226
-
-
Venneti, S.1
Lopresti, B.J.2
Wang, G.3
Hamilton, R.L.4
Mathis, C.A.5
Klunk, W.E.6
Apte, U.M.7
Wiley, C.A.8
-
21
-
-
35548986304
-
Microglia: Active sensor and versatile effector cells in the normal and pathologic brain
-
DOI 10.1038/nn1997, PII NN1997
-
Hanisch UK, Kettenmann H (2007) Microglia: Active sensor and versatile effector cells in the normal and pathologic brain. Nat Neurosci 10, 1387-1394 (Pubitemid 350014685)
-
(2007)
Nature Neuroscience
, vol.10
, Issue.11
, pp. 1387-1394
-
-
Hanisch, U.-K.1
Kettenmann, H.2
-
22
-
-
0038705106
-
Role of cytokines in the gene expression of amyloid β-protein precursor: Identification of a 5′-UTR-binding nuclear factor and its implications in Alzheimer's disease
-
Lahiri DK, Chen D, Vivien D, Ge YW, Greig NH, Rogers JT (2003) Role of cytokines in the gene expression of amyloid beta-protein precursor: Identification of a 5'-UTR-binding nuclear factor and its implications in Alzheimer's disease. J Alzheimers Dis 5, 81-90 (Pubitemid 36588346)
-
(2003)
Journal of Alzheimer's Disease
, vol.5
, Issue.2
, pp. 81-90
-
-
Lahiri, D.K.1
Chen, D.2
Vivien, D.3
Ge, Y.-W.4
Greig, N.H.5
Rogers, J.T.6
-
23
-
-
33947512432
-
Interferon-γ and tumor necrosis factor-α regulate amyloid-β plaque deposition and β-secretase expression in Swedish mutant APP transgenic mice
-
DOI 10.2353/ajpath.2007.060378
-
Yamamoto M, Kiyota T, Horiba M, Buescher JL, Walsh SM, Gendelman HE, Ikezu T (2007) Interferon-gamma and tumor necrosis factor-Alpha regulate amyloid-beta plaque deposition and beta-secretase expression in Swedish mutant APP transgenic mice. Am J Pathol 170, 680-692 (Pubitemid 47339404)
-
(2007)
American Journal of Pathology
, vol.170
, Issue.2
, pp. 680-692
-
-
Yamamoto, M.1
Kiyota, T.2
Horiba, M.3
Buescher, J.L.4
Walsh, S.M.5
Gendelman, H.E.6
Ikezu, T.7
-
24
-
-
10344238086
-
Tumor necrosis factor-α, interleukin-1β, and interferon-γ stimulate γ-secretase-mediated cleavage of amyloid precursor protein through a JNK-dependent MAPK pathway
-
DOI 10.1074/jbc.M402034200
-
Liao YF, Wang BJ, Cheng HT, Kuo LH, Wolfe MS (2004) Tumor necrosis factor-Alpha, interleukin-1beta, and interferon-gamma stimulate gamma-secretase-mediated cleavage of amyloid precursor protein through a JNKdependent MAPK pathway. J Biol Chem 279, 49523-49532 (Pubitemid 39625840)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.47
, pp. 49523-49532
-
-
Liaoi, Y.-F.1
Wang, B.-J.2
Cheng, H.-T.3
Kuo, L.-H.4
Wolfe, M.S.5
-
25
-
-
63849175251
-
Uniquely hominid features of adult human astrocytes
-
Oberheim NA, Takano T, Han X, He W, Lin JH, Wang F, Xu Q,Wyatt JD, PilcherW, Ojemann JG, Ransom BR, Goldman SA, NedergaardM(2009) Uniquely hominid features of adult human astrocytes. J Neurosci 29, 3276-3287
-
(2009)
J Neurosci
, vol.29
, pp. 3276-3287
-
-
Oberheim, N.A.1
Takano, T.2
Han, X.3
He, W.4
Lin, J.H.5
Wang, F.6
Xu, Q.7
Wyatt, J.D.8
Pilcher, W.9
Ojemann, J.G.10
Ransom, B.R.11
Goldman, S.A.12
Nedergaard, M.13
|