Multi-organ Abnormalities and mTORC1 Activation in Zebrafish Model of Multiple Acyl-CoA Dehydrogenase Deficiency

PLoS Genetics

Volumn 9, Issue 6, 2013, Pages

  Kim, Seok Hyung ^a   Scott, Sarah A ^a   Bennett, Michael J ^b   Carson, Robert P ^a   Fessel, Joshua ^a   Brown, H Alex ^a   Ess, Kevin C ^a  

^a VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHOLESTEROL; ELECTRON TRANSFERRING FLAVOPROTEIN; ELECTRON TRANSFERRING FLAVOPROTEIN A; MAMMALIAN TARGET OF RAPAMYCIN COMPLEX 1; RAPAMYCIN; SULFATIDE; TRIACYLGLYCEROL; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN DISEASE; CELL HYPERPLASIA; CELL PROLIFERATION; CELL SIZE; CELL SWELLING; CONTROLLED STUDY; DISEASE COURSE; DISEASE SEVERITY; DISORDERS OF MITOCHONDRIAL FUNCTIONS; ETFA GENE; GENE FUNCTION; GENE MUTATION; HISTOPATHOLOGY; HOMOZYGOTE; KIDNEY DISEASE; KIDNEY TUBULE CELL; LIVER CELL; LIVER DISEASE; MATERNAL NUTRITION; MULTIPLE ACYL COA DEHYDROGENASE DEFICIENCY; MUTANT; NEURAL STEM CELL; NONHUMAN; ORGAN INJURY; PHENOTYPE; PROTEIN INDUCTION; SIGNAL TRANSDUCTION; ZEBRA FISH;

ANIMALS; DISEASE MODELS, ANIMAL; ELECTRON-TRANSFERRING FLAVOPROTEINS; HUMANS; MITOCHONDRIA; MITOCHONDRIAL DISEASES; MOLECULAR TARGETED THERAPY; MULTIPLE ACYL COENZYME A DEHYDROGENASE DEFICIENCY; MULTIPROTEIN COMPLEXES; SIGNAL TRANSDUCTION; TOR SERINE-THREONINE KINASES; ZEBRAFISH;

ANIMALIA; DANIO RERIO;

EID: 84879647900     PISSN: 15537390     EISSN: 15537404     Source Type: Journal    
DOI: 10.1371/journal.pgen.1003563     Document Type: Article

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