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Volumn 1, Issue OCT, 2011, Pages

Glutathione S-transferases in pediatric cancer

Author keywords

Drug resistance; Epidemiology; Glutathione S transferase; Microsatellite; Pediatric cancer; Therapeutic target

Indexed keywords


EID: 84879630371     PISSN: None     EISSN: 2234943X     Source Type: Journal    
DOI: 10.3389/fonc.2011.00039     Document Type: Review
Times cited : (20)

References (110)
  • 2
    • 0033645405 scopus 로고    scopus 로고
    • Polymorphisms within glutathione S-transferase genes and initial response to glucocorticoids in childhood acute lymphoblastic leukaemia
    • Anderer, G., Schrappe, M., Brechlin, A. M., Lauten, M., Muti, P., Welte, K., and Stanulla, M. (2000). Polymorphisms within glutathione S-transferase genes and initial response to glucocorticoids in childhood acute lymphoblastic leukaemia. Pharmacogenetics 10, 715-726.
    • (2000) Pharmacogenetics , vol.10 , pp. 715-726
    • Anderer, G.1    Schrappe, M.2    Brechlin, A.M.3    Lauten, M.4    Muti, P.5    Welte, K.6    Stanulla, M.7
  • 3
    • 79954624221 scopus 로고    scopus 로고
    • Mitochondrial glutathione transferases involving a new function for membrane permeability transition pore regulation
    • Aniya, Y., and Imaizumi, N. (2011). Mitochondrial glutathione transferases involving a new function for membrane permeability transition pore regulation. Drug Metab. Rev. 43, 292-299.
    • (2011) Drug Metab. Rev. , vol.43 , pp. 292-299
    • Aniya, Y.1    Imaizumi, N.2
  • 4
    • 0031021397 scopus 로고    scopus 로고
    • Structure, catalytic mechanism, and evolution of the glutathione transferases
    • Armstrong, R. N. (1997). Structure, catalytic mechanism, and evolution of the glutathione transferases. Chem. Res. Toxicol. 10, 2-18.
    • (1997) Chem. Res. Toxicol. , vol.10 , pp. 2-18
    • Armstrong, R.N.1
  • 5
    • 34547888296 scopus 로고    scopus 로고
    • Polymorphisms in genes encoding drug metabolizing enzymes and their influence on the outcome of children with neuroblastoma
    • Ashton, L. J., Murray, J. E., Haber, M., Marshall, G. M., Ashley, D. M., and Norris, M. D. (2007). Polymorphisms in genes encoding drug metabolizing enzymes and their influence on the outcome of children with neuroblastoma. Pharmacogenet. Genomics 17, 709-717.
    • (2007) Pharmacogenet. Genomics , vol.17 , pp. 709-717
    • Ashton, L.J.1    Murray, J.E.2    Haber, M.3    Marshall, G.M.4    Ashley, D.M.5    Norris, M.D.6
  • 6
    • 0031866258 scopus 로고    scopus 로고
    • Altered expression of resistance associated genes in hepatoblastoma xenografts incorporated into mice following treatment with adriamycin or cisplatin
    • Bader, P., Fuchs, J., Wenderoth, M., von Schweinitz, D., Niethammer, D., and Beck, J. F. (1998). Altered expression of resistance associated genes in hepatoblastoma xenografts incorporated into mice following treatment with adriamycin or cisplatin. Anticancer Res. 18, 3127-3132.
    • (1998) Anticancer Res. , vol.18 , pp. 3127-3132
    • Bader, P.1    Fuchs, J.2    Wenderoth, M.3    von Schweinitz, D.4    Niethammer, D.5    Beck, J.F.6
  • 7
    • 0030967073 scopus 로고    scopus 로고
    • Glutathione transferases catalyse the detoxication of oxidized metabolites (?-quinones) of catecholamines and may serve as an antioxidant system preventing degenerative cellular processes
    • Baez, S., Segura-Aguilar, J., Widersten, M., Johansson, A. S., and Mannervik, B. (1997). Glutathione transferases catalyse the detoxication of oxidized metabolites (?-quinones) of catecholamines and may serve as an antioxidant system preventing degenerative cellular processes. Biochem. J. 324, 25-28.
    • (1997) Biochem. J. , vol.324 , pp. 25-28
    • Baez, S.1    Segura-Aguilar, J.2    Widersten, M.3    Johansson, A.S.4    Mannervik, B.5
  • 8
    • 77449135890 scopus 로고    scopus 로고
    • Substrate specificity combined with stereopromiscuity in glutathione transferase A4-4-dependent metabolism of 4-hydroxynonenal
    • Balogh, L. M., Le Trong, I., Kripps, K. A., Shireman, L. M., Stenkamp, R. E., Zhang, W., Mannervik, B., and Atkins, W. M. (2011). Substrate specificity combined with stereopromiscuity in glutathione transferase A4-4-dependent metabolism of 4-hydroxynonenal. Biochemistry 49, 1541-1548.
    • (2011) Biochemistry , vol.49 , pp. 1541-1548
    • Balogh, L.M.1    Le Trong, I.2    Kripps, K.A.3    Shireman, L.M.4    Stenkamp, R.E.5    Zhang, W.6    Mannervik, B.7    Atkins, W.M.8
  • 9
    • 0037969835 scopus 로고    scopus 로고
    • Characterization of MTHFR, GSTM1, GSTT1, GSTP1, and CYP1A1 genotypes in childhood acute leukemia
    • Balta, G., Yuksek, N., Ozyurek, E., Ertem, U., Hicsonmez, G., Altay, C., and Gurgey, A. (2003). Characterization of MTHFR, GSTM1, GSTT1, GSTP1, and CYP1A1 genotypes in childhood acute leukemia. Am. J. Hematol. 73, 154-160.
    • (2003) Am. J. Hematol. , vol.73 , pp. 154-160
    • Balta, G.1    Yuksek, N.2    Ozyurek, E.3    Ertem, U.4    Hicsonmez, G.5    Altay, C.6    Gurgey, A.7
  • 11
    • 0028036292 scopus 로고
    • Detoxication of base propenals and other α,β-unsaturated aldehyde products of radical reactions and lipid peroxidation by human glutathione transferase
    • Berhane, K., Widersten, M., Engstrom, A., Kozarich, J. W., and Mannervik, B. (1994). Detoxication of base propenals and other α,β-unsaturated aldehyde products of radical reactions and lipid peroxidation by human glutathione transferase. Proc. Natl. Acad. Sci. U.S.A. 91, 1480-1484.
    • (1994) Proc. Natl. Acad. Sci. U.S.A. , vol.91 , pp. 1480-1484
    • Berhane, K.1    Widersten, M.2    Engstrom, A.3    Kozarich, J.W.4    Mannervik, B.5
  • 12
    • 0033917994 scopus 로고    scopus 로고
    • Identification of mu-class glutathione transferases M2-2 and M3-3 as cytosolic prostaglandin E synthases in the human brain
    • Beuckmann, C. T., Fujimori, K., Urade, Y., and Hayaishi, O. (2000). Identification of mu-class glutathione transferases M2-2 and M3-3 as cytosolic prostaglandin E synthases in the human brain. Neurochem. Res. 25, 733-738.
    • (2000) Neurochem. Res. , vol.25 , pp. 733-738
    • Beuckmann, C.T.1    Fujimori, K.2    Urade, Y.3    Hayaishi, O.4
  • 13
    • 38349182228 scopus 로고    scopus 로고
    • S-(4-nitrophenacyl)glutathione is a specific substrate for glutathione transferase omega 1-1
    • Board, P. G., Coggan, M., Cappello, J., Zhou, H., Oakley, A. J., and Anders, M. W. (2008). S-(4-nitrophenacyl)glutathione is a specific substrate for glutathione transferase omega 1-1. Anal. Biochem. 374, 25-30.
    • (2008) Anal. Biochem. , vol.374 , pp. 25-30
    • Board, P.G.1    Coggan, M.2    Cappello, J.3    Zhou, H.4    Oakley, A.J.5    Anders, M.W.6
  • 15
    • 33747179265 scopus 로고    scopus 로고
    • Relevance of the deletion polymorphisms of the glutathione S-transferases GSTT1 and GSTM1 in pharmacology and toxicology
    • Bolt, H. M., and Their, R. (2006). Relevance of the deletion polymorphisms of the glutathione S-transferases GSTT1 and GSTM1 in pharmacology and toxicology. Curr. Drug Metab. 7, 613-628.
    • (2006) Curr. Drug Metab. , vol.7 , pp. 613-628
    • Bolt, H.M.1    Their, R.2
  • 16
    • 0000259325 scopus 로고
    • An enzyme from rat liver catalyzing conjugations with glutathione
    • Booth, J., Boyland, E., and Sims, P. (1961). An enzyme from rat liver catalyzing conjugations with glutathione. Biochem. J. 79, 516-524.
    • (1961) Biochem. J. , vol.79 , pp. 516-524
    • Booth, J.1    Boyland, E.2    Sims, P.3
  • 17
    • 0031032786 scopus 로고    scopus 로고
    • Higher frequency of glutathione S-transferase deletions in black children with acute lymphoblastic leukemia
    • Chen, C. L., Liu, Q., Pui, C. H., Rivera, G. K., Sandlund, J. T., Ribeiro, R., Evans, W. E., and Relling, M. V. (1997). Higher frequency of glutathione S-transferase deletions in black children with acute lymphoblastic leukemia. Blood 89, 1701-1707.
    • (1997) Blood , vol.89 , pp. 1701-1707
    • Chen, C.L.1    Liu, Q.2    Pui, C.H.3    Rivera, G.K.4    Sandlund, J.T.5    Ribeiro, R.6    Evans, W.E.7    Relling, M.V.8
  • 19
    • 0034637708 scopus 로고    scopus 로고
    • Expression of hGSTP1 alleles in human lung and catalytic activity of the native protein variants towards 1-chloro-2,4-dinitrobenzene, 4-vinylpyridine and (+)-anti benzo[a]pyrene-7,8-diol-9,10-oxide
    • Coles, B., Yang, M., Lang, N. P., and Kadlubar, F. F. (2000). Expression of hGSTP1 alleles in human lung and catalytic activity of the native protein variants towards 1-chloro-2,4-dinitrobenzene, 4-vinylpyridine and (+)-anti benzo[a]pyrene-7,8-diol-9,10-oxide. Cancer Lett. 156, 167-175.
    • (2000) Cancer Lett. , vol.156 , pp. 167-175
    • Coles, B.1    Yang, M.2    Lang, N.P.3    Kadlubar, F.F.4
  • 20
    • 0000112444 scopus 로고
    • A liver enzyme that conjugates sulfobromophthalein with glutathione
    • Coombes, B., and Stakelum, G. S. (1961). A liver enzyme that conjugates sulfobromophthalein with glutathione. J. Clin. Invest. 40, 981-988.
    • (1961) J. Clin. Invest. , vol.40 , pp. 981-988
    • Coombes, B.1    Stakelum, G.S.2
  • 21
    • 0036660410 scopus 로고    scopus 로고
    • Glutathione S-transferase genotypes, genetic susceptibility, and outcome of therapy in childhood acute lymphoblastic leukemia
    • Davies, S. M., Bhatia, S., Ross, J. A., Kiffmeyer, W. R., Gaynon, P. S., Radloff, G. A., Robison, L. L., and Perentesis, J. P. (2002). Glutathione S-transferase genotypes, genetic susceptibility, and outcome of therapy in childhood acute lymphoblastic leukemia. Blood 100, 67-71.
    • (2002) Blood , vol.100 , pp. 67-71
    • Davies, S.M.1    Bhatia, S.2    Ross, J.A.3    Kiffmeyer, W.R.4    Gaynon, P.S.5    Radloff, G.A.6    Robison, L.L.7    Perentesis, J.P.8
  • 25
    • 0037163046 scopus 로고    scopus 로고
    • Activation of the p38 signaling pathway by heat shock involves the dissociation of glutathione s-transferase Mu from Ask1
    • Dorion, S., Lambert, H., and Landry, J. (2002). Activation of the p38 signaling pathway by heat shock involves the dissociation of glutathione s-transferase Mu from Ask1. J. Biol. Chem. 277, 30792-30797.
    • (2002) J. Biol. Chem. , vol.277 , pp. 30792-30797
    • Dorion, S.1    Lambert, H.2    Landry, J.3
  • 28
    • 79954625549 scopus 로고    scopus 로고
    • Regulation of the cardiac muscle ryanodine receptor by glutathione transferases
    • Dulhunty, A. F., Hewawasam, R., Liu, D., Casarotto, M. G., and Board, P. G. (2011). Regulation of the cardiac muscle ryanodine receptor by glutathione transferases. Drug Metab. Rev. 43, 236-252.
    • (2011) Drug Metab. Rev. , vol.43 , pp. 236-252
    • Dulhunty, A.F.1    Hewawasam, R.2    Liu, D.3    Casarotto, M.G.4    Board, P.G.5
  • 29
    • 77952581540 scopus 로고    scopus 로고
    • GSTM1, GSTT1, GSTP1, GSTA1 and colorectal cancer risk: a comprehensive meta-analysis
    • Economopoulos, K. P., and Sergentanis, T. N. (2010). GSTM1, GSTT1, GSTP1, GSTA1 and colorectal cancer risk: a comprehensive meta-analysis. Eur. J. Cancer 46, 1617-1631.
    • (2010) Eur. J. Cancer , vol.46 , pp. 1617-1631
    • Economopoulos, K.P.1    Sergentanis, T.N.2
  • 31
    • 79954621888 scopus 로고    scopus 로고
    • Sigma-class glutathione transferases
    • Flanagan, J. U., and Smythe, M. L. (2011). Sigma-class glutathione transferases. Drug Metab. Rev. 43, 194-214.
    • (2011) Drug Metab. Rev. , vol.43 , pp. 194-214
    • Flanagan, J.U.1    Smythe, M.L.2
  • 32
    • 77955660007 scopus 로고    scopus 로고
    • Emergent properties of EWS/FLI regulation via GGAA microsatellites in Ewing's sarcoma
    • Gangwal, K., Close, D., Enriquez, C. A., Hill, C. P., and Lessnick, S. L. (2010). Emergent properties of EWS/FLI regulation via GGAA microsatellites in Ewing's sarcoma. Genes Cancer 1, 177-187.
    • (2010) Genes Cancer , vol.1 , pp. 177-187
    • Gangwal, K.1    Close, D.2    Enriquez, C.A.3    Hill, C.P.4    Lessnick, S.L.5
  • 34
    • 53649107137 scopus 로고    scopus 로고
    • DAX1, a direct target of EWS/FLI oncoprotein, is a principle regulator of cell-cycle progression in Ewing's tumor cells
    • Garcia-Aragoncillo, E., Carillo, J., Lalli, E., Agra, N., Gómez-López, G., Pestaña, A., and Alonso, J. (2008). DAX1, a direct target of EWS/FLI oncoprotein, is a principle regulator of cell-cycle progression in Ewing's tumor cells. Oncogene 27, 6034-6043.
    • (2008) Oncogene , vol.27 , pp. 6034-6043
    • Garcia-Aragoncillo, E.1    Carillo, J.2    Lalli, E.3    Agra, N.4    Gómez-López, G.5    Pestaña, A.6    Alonso, J.7
  • 35
    • 40449106476 scopus 로고    scopus 로고
    • Glutathione S-transferase P1 genotypes, genetic susceptibility and outcome of therapy in thai childhood acute lymphoblastic leukemia
    • Gatedee, J., Pakakassama, S., Muangman, S., and Pongstaporn, W. (2007). Glutathione S-transferase P1 genotypes, genetic susceptibility and outcome of therapy in thai childhood acute lymphoblastic leukemia. Asian Pac. J. Cancer Prev. 8, 294-296.
    • (2007) Asian Pac. J. Cancer Prev. , vol.8 , pp. 294-296
    • Gatedee, J.1    Pakakassama, S.2    Muangman, S.3    Pongstaporn, W.4
  • 36
    • 0032874845 scopus 로고    scopus 로고
    • Glutathione and glutathione-dependent enzymes represent a co-ordinately regulated defence against oxidative stress
    • Hayes, J. D., and McLellan, L. I. (1999). Glutathione and glutathione-dependent enzymes represent a co-ordinately regulated defence against oxidative stress. Free Radic. Res. 31, 273-300.
    • (1999) Free Radic. Res. , vol.31 , pp. 273-300
    • Hayes, J.D.1    McLellan, L.I.2
  • 37
    • 0033828113 scopus 로고    scopus 로고
    • Glutathione s-transferase polymorphisms and their biological consequences
    • Hayes, J. D., and Strange, R. C. (2000). Glutathione s-transferase polymorphisms and their biological consequences. Pharmacology 61, 154-166.
    • (2000) Pharmacology , vol.61 , pp. 154-166
    • Hayes, J.D.1    Strange, R.C.2
  • 38
    • 79954617744 scopus 로고    scopus 로고
    • Knockout and transgenic mice in glutathione transferase research
    • Henderson, C. J., and Wolf, C. R. (2011). Knockout and transgenic mice in glutathione transferase research. Drug Metab. Rev. 43, 152-164.
    • (2011) Drug Metab. Rev. , vol.43 , pp. 152-164
    • Henderson, C.J.1    Wolf, C.R.2
  • 39
    • 0024499993 scopus 로고
    • Differential expression of alpha and pi isoenzymes of glutathione s-transferase in developing human kidney
    • Hiley, C., Bell, J., Hume, R., and Strange, R. (1989). Differential expression of alpha and pi isoenzymes of glutathione s-transferase in developing human kidney. Biochim. Biophys. Acta 990, 321-324.
    • (1989) Biochim. Biophys. Acta , vol.990 , pp. 321-324
    • Hiley, C.1    Bell, J.2    Hume, R.3    Strange, R.4
  • 40
    • 77949612842 scopus 로고    scopus 로고
    • Glutathione s-transferase M1 inhibits dexamethasone-induced apoptosis in association with the suppression of Bim through dual mechanisms in a lymphoblastic leukemia cell line
    • Hosono, N., Kishi, S., Iho, S., Urasaki, Y., Yoshida, A., Kurooka, H., Yokota, Y., and Ueda, T. (2010). Glutathione s-transferase M1 inhibits dexamethasone-induced apoptosis in association with the suppression of Bim through dual mechanisms in a lymphoblastic leukemia cell line. Cancer Sci. 101, 767-773.
    • (2010) Cancer Sci. , vol.101 , pp. 767-773
    • Hosono, N.1    Kishi, S.2    Iho, S.3    Urasaki, Y.4    Yoshida, A.5    Kurooka, H.6    Yokota, Y.7    Ueda, T.8
  • 41
    • 0031238820 scopus 로고    scopus 로고
    • Mechanism of differential catalytic efficiency of two polymorphic forms of human glutathione S-transferase P1-1 in the glutathione conjugation of carcinogenic diol epoxides of chrysene
    • Hu, X., Ji, X., Srivastava, S. K., Xia, H., Awasthi, S., Nanduri, B., Awasthi, Y. C., Zimniak, P., and Singh, S. V. (1997a). Mechanism of differential catalytic efficiency of two polymorphic forms of human glutathione S-transferase P1-1 in the glutathione conjugation of carcinogenic diol epoxides of chrysene. Arch. Biochem. Biophys. 345, 32-38.
    • (1997) Arch. Biochem. Biophys. , vol.345 , pp. 32-38
    • Hu, X.1    Ji, X.2    Srivastava, S.K.3    Xia, H.4    Awasthi, S.5    Nanduri, B.6    Awasthi, Y.C.7    Zimniak, P.8    Singh, S.V.9
  • 42
    • 0031577161 scopus 로고    scopus 로고
    • Active site architecture of polymorphic forms of human glutathione S-transferase P1-1 accounts for their enantioselectivity and disparate activity in the glutathione conjugation of 7β,8α-dihydroxy-9α,10α-oxy-7,8,9,10-tetrahydrobenzo(α)pyrene
    • Hu, X., O'Donnell, R., Srivastava, S. K., Xia, H., Zimniak, P., Nanduri, B., Bleicher, R. J., Awasthi, S., Awasthi, Y. C., Ji, X., and Singh, S. V. (1997b). Active site architecture of polymorphic forms of human glutathione S-transferase P1-1 accounts for their enantioselectivity and disparate activity in the glutathione conjugation of 7β,8α-dihydroxy-9α,10α-oxy-7,8,9,10-tetrahydrobenzo(α)pyrene. Biochem. Biophys. Res. Commun. 235, 424-428.
    • (1997) Biochem. Biophys. Res. Commun. , vol.235 , pp. 424-428
    • Hu, X.1    O'Donnell, R.2    Srivastava, S.K.3    Xia, H.4    Zimniak, P.5    Nanduri, B.6    Bleicher, R.J.7    Awasthi, S.8    Awasthi, Y.C.9    Ji, X.10    Singh, S.V.11
  • 43
    • 0031577576 scopus 로고    scopus 로고
    • Activity of four allelic forms of glutathione S-transferase hGSTP1-1 for diol epoxides of polycyclic aromatic hydrocarbons
    • Hu, X., Xia, H., Srivastava, S. K., Herzog, C., Awasthi, Y. C., Ji, X., Zimniak, P., and Singh, S. V. (1997c). Activity of four allelic forms of glutathione S-transferase hGSTP1-1 for diol epoxides of polycyclic aromatic hydrocarbons. Biochem. Biophys. Res. Commun. 238, 397-402.
    • (1997) Biochem. Biophys. Res. Commun. , vol.238 , pp. 397-402
    • Hu, X.1    Xia, H.2    Srivastava, S.K.3    Herzog, C.4    Awasthi, Y.C.5    Ji, X.6    Zimniak, P.7    Singh, S.V.8
  • 44
    • 0032401820 scopus 로고    scopus 로고
    • Catalytic efficiencies of allelic variants of human glutathione-transferase P1-1 toward carcinogenic anti-diol epoxides of benzo[c]phenanthrene and benzo[g]chrysene
    • Hu, X., Xia, H., Srivastava, S. K., Pal, A., Awasthi, Y. C., Zimniak, P., and Singh, S. V. (1998). Catalytic efficiencies of allelic variants of human glutathione-transferase P1-1 toward carcinogenic anti-diol epoxides of benzo[c]phenanthrene and benzo[g]chrysene. Cancer Res. 58, 5340-5343.
    • (1998) Cancer Res. , vol.58 , pp. 5340-5343
    • Hu, X.1    Xia, H.2    Srivastava, S.K.3    Pal, A.4    Awasthi, Y.C.5    Zimniak, P.6    Singh, S.V.7
  • 45
    • 0030787417 scopus 로고    scopus 로고
    • The GST T1 and CYP2E1 genotypes are possible factors causing vinyl chloride induced abnormal liver function
    • Huang, C. Y., Huang, K. L., Cheng, T. J., Wang, J. D., and Hsieh, L. L. (1997). The GST T1 and CYP2E1 genotypes are possible factors causing vinyl chloride induced abnormal liver function. Arch. Toxicol. 71, 482-488.
    • (1997) Arch. Toxicol. , vol.71 , pp. 482-488
    • Huang, C.Y.1    Huang, K.L.2    Cheng, T.J.3    Wang, J.D.4    Hsieh, L.L.5
  • 46
    • 70349560286 scopus 로고    scopus 로고
    • Expression of thymidylate synthase and glutathione-s-transferase pi in patients with esophageal squamous cell carcinoma
    • Huang, J. X., Li, F. Y., Xiao, W., Song, Z. X., Qian, R. Y., Chen, P., and Salminen, E. (2009). Expression of thymidylate synthase and glutathione-s-transferase pi in patients with esophageal squamous cell carcinoma. World J. Gastroenterol. 15, 4316-4321.
    • (2009) World J. Gastroenterol. , vol.15 , pp. 4316-4321
    • Huang, J.X.1    Li, F.Y.2    Xiao, W.3    Song, Z.X.4    Qian, R.Y.5    Chen, P.6    Salminen, E.7
  • 47
    • 0032519517 scopus 로고    scopus 로고
    • Human glutathione transferase A4-4: an alpha class enzyme with high catalytic efficiency in the conjugation of 4-hydroxynonenal and other genotoxic products of lipid peroxidation
    • Hubatsch, I., Ridderstrom, M., and Mannervik, B. (1998). Human glutathione transferase A4-4: an alpha class enzyme with high catalytic efficiency in the conjugation of 4-hydroxynonenal and other genotoxic products of lipid peroxidation. Biochem. J. 330, 175-179.
    • (1998) Biochem. J. , vol.330 , pp. 175-179
    • Hubatsch, I.1    Ridderstrom, M.2    Mannervik, B.3
  • 48
    • 0029840329 scopus 로고    scopus 로고
    • Identification and characterization of a novel human microsomal glutathione S-transferase with leukotrience C4 synthase activity and significant sequence identity to 5-lipoxygenase-activating protein and leukotriene C4 synthase
    • Jakobsson, P. J., Mancini, J. A., and Ford-Hutchinson, A. W. (1996). Identification and characterization of a novel human microsomal glutathione S-transferase with leukotrience C4 synthase activity and significant sequence identity to 5-lipoxygenase-activating protein and leukotriene C4 synthase. J. Biol. Chem. 271, 22203-22210.
    • (1996) J. Biol. Chem. , vol.271 , pp. 22203-22210
    • Jakobsson, P.J.1    Mancini, J.A.2    Ford-Hutchinson, A.W.3
  • 49
    • 0030923439 scopus 로고    scopus 로고
    • Identification and characterization of a novel microsomal enzyme with glutathione-dependent transferase and peroxidase activities
    • Jakobsson, P. J., Mancini, J. A., Riendeau, D., and Ford-Hutchinson, A. W. (1997). Identification and characterization of a novel microsomal enzyme with glutathione-dependent transferase and peroxidase activities. J. Biol. Chem. 272, 22934-22939.
    • (1997) J. Biol. Chem. , vol.272 , pp. 22934-22939
    • Jakobsson, P.J.1    Mancini, J.A.2    Riendeau, D.3    Ford-Hutchinson, A.W.4
  • 50
    • 0346656658 scopus 로고    scopus 로고
    • GST polymorphisms and occurrence of second neoplasms after treatment of childhood leukemia
    • Jazbec, J., Aplenc, R., Dolzan, V., Debeljak, M., and Jereb, B. (2003). GST polymorphisms and occurrence of second neoplasms after treatment of childhood leukemia. Leukemia 17, 2540-2542.
    • (2003) Leukemia , vol.17 , pp. 2540-2542
    • Jazbec, J.1    Aplenc, R.2    Dolzan, V.3    Debeljak, M.4    Jereb, B.5
  • 51
    • 0035980083 scopus 로고    scopus 로고
    • Human glutathione transferase A3-3, a highly efficient catalyst of double-bond isomerization in the biosynthetic pathway of steroid hormones
    • Johansson, A. S., and Mannervik, B. (2001). Human glutathione transferase A3-3, a highly efficient catalyst of double-bond isomerization in the biosynthetic pathway of steroid hormones. J. Biol. Chem. 276, 33061-33065.
    • (2001) J. Biol. Chem. , vol.276 , pp. 33061-33065
    • Johansson, A.S.1    Mannervik, B.2
  • 52
    • 78049369447 scopus 로고    scopus 로고
    • Multiple roles of microsomal glutathione transferase 1 in cellular protection: a mechanistic study
    • Johansson, K., Jarvliden, J., Gogvadze, V., and Morgenstern, R. (2010). Multiple roles of microsomal glutathione transferase 1 in cellular protection: a mechanistic study. Free Radic. Biol. Med. 49, 1638-1645.
    • (2010) Free Radic. Biol. Med. , vol.49 , pp. 1638-1645
    • Johansson, K.1    Jarvliden, J.2    Gogvadze, V.3    Morgenstern, R.4
  • 53
    • 0030894660 scopus 로고    scopus 로고
    • Conjugation of highly reactive aflatoxin B1 exo-8,9-epoxide catalysed by rat and human glutathione transferases: estimation of kinetic parameters
    • Johnson, W. W., Ueng, Y. F., Widersten, W., Mannervik, B., Hayes, J. D., Sherratt, P. J., Ketterer, B., and Guengerich, F. P. (1997). Conjugation of highly reactive aflatoxin B1 exo-8,9-epoxide catalysed by rat and human glutathione transferases: estimation of kinetic parameters. Biochemistry 36, 3056-3060.
    • (1997) Biochemistry , vol.36 , pp. 3056-3060
    • Johnson, W.W.1    Ueng, Y.F.2    Widersten, W.3    Mannervik, B.4    Hayes, J.D.5    Sherratt, P.J.6    Ketterer, B.7    Guengerich, F.P.8
  • 54
    • 4744363964 scopus 로고    scopus 로고
    • Genetic polymorphism of CYP1A1, CYP2D6, GSTM1 and GSTT1 and susceptibility to acute lymphoblastic leukaemia in Indian children
    • Joseph, T., Kusumakumary, P., Chacko, P., Abraham, A., and Pillai, M. R. (2004). Genetic polymorphism of CYP1A1, CYP2D6, GSTM1 and GSTT1 and susceptibility to acute lymphoblastic leukaemia in Indian children. Pediatr. Blood Cancer 43, 560-567.
    • (2004) Pediatr. Blood Cancer , vol.43 , pp. 560-567
    • Joseph, T.1    Kusumakumary, P.2    Chacko, P.3    Abraham, A.4    Pillai, M.R.5
  • 55
    • 77954644015 scopus 로고    scopus 로고
    • Genetic variations in human glutathione transferase enzymes: significance for pharmacology and toxicology
    • Josephy, P. D. (2010). Genetic variations in human glutathione transferase enzymes: significance for pharmacology and toxicology. Hum. Genomics Proteomics 2010, 876940-876953.
    • (2010) Hum. Genomics Proteomics , vol.2010 , pp. 876940-876953
    • Josephy, P.D.1
  • 57
    • 13844256990 scopus 로고    scopus 로고
    • Double deletions of glutathione S-transferase genes (GSTM1 and GSTT1) reduce the risk of early relapse in childhood B-lineage acute lymphoblastic leukaemia (ALL)
    • Kham, S. K., Soh, C. K., Heng, C. K., Ariffin, H., Quah, T. C., and Yeoh, A. E. (2004). Double deletions of glutathione S-transferase genes (GSTM1 and GSTT1) reduce the risk of early relapse in childhood B-lineage acute lymphoblastic leukaemia (ALL). Ann. Acad. Med. Singapore 33, S83-S85.
    • (2004) Ann. Acad. Med. Singapore , vol.33
    • Kham, S.K.1    Soh, C.K.2    Heng, C.K.3    Ariffin, H.4    Quah, T.C.5    Yeoh, A.E.6
  • 58
    • 33845344030 scopus 로고    scopus 로고
    • NR0B1 is required for the oncogenic phenotype mediated by EWS/FLI in Ewing's sarcoma
    • Kinsey, M., Smith, R., and Lessnick, S. L. (2006). NR0B1 is required for the oncogenic phenotype mediated by EWS/FLI in Ewing's sarcoma. Mol. Cancer Res. 4, 851-859.
    • (2006) Mol. Cancer Res. , vol.4 , pp. 851-859
    • Kinsey, M.1    Smith, R.2    Lessnick, S.L.3
  • 59
    • 0033105657 scopus 로고    scopus 로고
    • Susceptibility to childhood acute lymphoblastic leukemia: influence of CYP1A1, CYP2D6, GSTM1, and GSTT1 genetic polymorphisms
    • Krajinovic, M., Labuda, D., Richer, C., Karimi, S., and Sinnett, D. (1999). Susceptibility to childhood acute lymphoblastic leukemia: influence of CYP1A1, CYP2D6, GSTM1, and GSTT1 genetic polymorphisms. Blood 93, 1496-1501.
    • (1999) Blood , vol.93 , pp. 1496-1501
    • Krajinovic, M.1    Labuda, D.2    Richer, C.3    Karimi, S.4    Sinnett, D.5
  • 60
    • 0036866625 scopus 로고    scopus 로고
    • Glutathione S-transferase P1 genetic polymorphisms and susceptibility to childhood acute lymphoblastic leukaemia
    • Krajinovic, M., Labuda, D., and Sinnett, D. (2002). Glutathione S-transferase P1 genetic polymorphisms and susceptibility to childhood acute lymphoblastic leukaemia. Pharmacogenetics 12, 655-658.
    • (2002) Pharmacogenetics , vol.12 , pp. 655-658
    • Krajinovic, M.1    Labuda, D.2    Sinnett, D.3
  • 61
    • 70450184674 scopus 로고    scopus 로고
    • GSTM4 is a microsatellite-containing EWS/FLI target involved in Ewing's sarcoma oncogenesis and therapeutic resistance
    • Luo, W., Gangwal, K., Sankar, S., Boucher, K. M., Thomas, D., and Lessnick, S. L. (2009). GSTM4 is a microsatellite-containing EWS/FLI target involved in Ewing's sarcoma oncogenesis and therapeutic resistance. Oncogene 28, 4126-4132.
    • (2009) Oncogene , vol.28 , pp. 4126-4132
    • Luo, W.1    Gangwal, K.2    Sankar, S.3    Boucher, K.M.4    Thomas, D.5    Lessnick, S.L.6
  • 63
    • 0035830931 scopus 로고    scopus 로고
    • Cloning, expression, and up-regulation of inducible rat prostaglandin e synthase during lipopolysaccharide-induced pyresis and adjuvant-induced arthritis
    • Mancini, J. A., Blood, K., Guay, J., Gordon, R., Claveau, D., Chan, C. C., and Riendeau, D. (2001). Cloning, expression, and up-regulation of inducible rat prostaglandin e synthase during lipopolysaccharide-induced pyresis and adjuvant-induced arthritis. J. Biol. Chem. 279, 4469-4475.
    • (2001) J. Biol. Chem. , vol.279 , pp. 4469-4475
    • Mancini, J.A.1    Blood, K.2    Guay, J.3    Gordon, R.4    Claveau, D.5    Chan, C.C.6    Riendeau, D.7
  • 64
    • 71049152487 scopus 로고    scopus 로고
    • Response to glucocorticoids and toxicity in childhood acute lymphoblastic leukemia: role of polymorphisms of genes involved in glucocorticoid response
    • Marino, S., Verzegnassi, F., Tamaro, P., Stocco, G., Bartoli, F., Decorti, G., and Rabusin, M. (2009). Response to glucocorticoids and toxicity in childhood acute lymphoblastic leukemia: role of polymorphisms of genes involved in glucocorticoid response. Pediatr. Blood Cancer 53, 984-991.
    • (2009) Pediatr. Blood Cancer , vol.53 , pp. 984-991
    • Marino, S.1    Verzegnassi, F.2    Tamaro, P.3    Stocco, G.4    Bartoli, F.5    Decorti, G.6    Rabusin, M.7
  • 65
    • 78649683899 scopus 로고    scopus 로고
    • Urinary glutathione S-transferases in the pathogenesis and diagnostic evaluation of acute kidney injury following cardiac surgery: a critical review
    • McMahon, B. A., Koyner, J. L., and Murray, P. T. (2010). Urinary glutathione S-transferases in the pathogenesis and diagnostic evaluation of acute kidney injury following cardiac surgery: a critical review. Curr. Opin. Crit. Care 16, 550-555.
    • (2010) Curr. Opin. Crit. Care , vol.16 , pp. 550-555
    • McMahon, B.A.1    Koyner, J.L.2    Murray, P.T.3
  • 66
    • 79952336337 scopus 로고    scopus 로고
    • JS-K, a nitric oxide-releasing prodrug, induces breast cancer cell death while sparing normal mammary epithelial cells
    • McMurtry, V., Saavedra, J. E., Nieves-Alicea, R., Simeone, A. M., Keefer, L. K., and Tari, A. M. (2011). JS-K, a nitric oxide-releasing prodrug, induces breast cancer cell death while sparing normal mammary epithelial cells. Int. J. Oncol. 38, 963-971.
    • (2011) Int. J. Oncol. , vol.38 , pp. 963-971
    • McMurtry, V.1    Saavedra, J.E.2    Nieves-Alicea, R.3    Simeone, A.M.4    Keefer, L.K.5    Tari, A.M.6
  • 68
    • 77952690934 scopus 로고    scopus 로고
    • Glutathione-S-transferase genes and asthma phenotypes: a human genome epidemiology (HuGE) systematic review and meta-analysis including unpublished data
    • Minelli, C., Granell, R., Newson, R., Rose-Zerilli, M. J., Torrent, M., Ring, S. M., Holloway, J. W., Shaheen, S. O., and Henderson, J. A. (2010). Glutathione-S-transferase genes and asthma phenotypes: a human genome epidemiology (HuGE) systematic review and meta-analysis including unpublished data. Int. J. Epidemiol. 39, 539-562.
    • (2010) Int. J. Epidemiol. , vol.39 , pp. 539-562
    • Minelli, C.1    Granell, R.2    Newson, R.3    Rose-Zerilli, M.J.4    Torrent, M.5    Ring, S.M.6    Holloway, J.W.7    Shaheen, S.O.8    Henderson, J.A.9
  • 69
    • 0030065613 scopus 로고    scopus 로고
    • Isozyme-specific glutathione S-transferase inhibitors potentiate drug sensitivity in cultured human tumor cell lines
    • Morgan, A. S., Ciaccio, P. J., Tew, K. D., and Kauvar, L. M. (1996). Isozyme-specific glutathione S-transferase inhibitors potentiate drug sensitivity in cultured human tumor cell lines. Cancer Chemother. Pharmacol. 37, 363-370.
    • (1996) Cancer Chemother. Pharmacol. , vol.37 , pp. 363-370
    • Morgan, A.S.1    Ciaccio, P.J.2    Tew, K.D.3    Kauvar, L.M.4
  • 71
    • 0034650803 scopus 로고    scopus 로고
    • Redox regulation of glutathione S-transferase induction by benzyl isothiocyanate: correlation of enzyme induction with the formation of reactive oxygen intermediates
    • Nakamura, Y., Ohigashi, H., Masuda, S., Murakami, A., Morimitsu, Y., Kawamoto, Y., Osawa, T., Imagawa, M., and Uchida, K. (2000). Redox regulation of glutathione S-transferase induction by benzyl isothiocyanate: correlation of enzyme induction with the formation of reactive oxygen intermediates. Cancer Res. 60, 219-225.
    • (2000) Cancer Res. , vol.60 , pp. 219-225
    • Nakamura, Y.1    Ohigashi, H.2    Masuda, S.3    Murakami, A.4    Morimitsu, Y.5    Kawamoto, Y.6    Osawa, T.7    Imagawa, M.8    Uchida, K.9
  • 72
    • 84860390394 scopus 로고    scopus 로고
    • Engineering GST M2-2 for high activity with indene 1,2-oxide and indication of an H-site residue sustaining catalytic promiscuity
    • Norrgard, M. A., and Mannervik, B. (2011). Engineering GST M2-2 for high activity with indene 1,2-oxide and indication of an H-site residue sustaining catalytic promiscuity. J. Mol. Biol. 412, 111-120.
    • (2011) J. Mol. Biol. , vol.412 , pp. 111-120
    • Norrgard, M.A.1    Mannervik, B.2
  • 73
    • 79954572279 scopus 로고    scopus 로고
    • Glutathione transferases: a structural perspective
    • Oakley, A. (2011). Glutathione transferases: a structural perspective. Drug Metab. Rev. 43, 138-151.
    • (2011) Drug Metab. Rev. , vol.43 , pp. 138-151
    • Oakley, A.1
  • 74
    • 33749661948 scopus 로고    scopus 로고
    • Identification of target genes in their native cellular context: an analysis of EWS/FLI in Ewing's sarcoma
    • Owen, L. A., and Lessnick, S. L. (2006). Identification of target genes in their native cellular context: an analysis of EWS/FLI in Ewing's sarcoma. Cell Cycle 5, 2049-2053.
    • (2006) Cell Cycle , vol.5 , pp. 2049-2053
    • Owen, L.A.1    Lessnick, S.L.2
  • 77
    • 63549114826 scopus 로고    scopus 로고
    • Polymorphism of glutathione S-transferase Omega gene: association with risk of childhood acute lymphoblastic leukemia
    • Pongstaporn, W., Pakakasama, S., Sanguansin, S., Hongeng, S., and Petmitr, S. (2009). Polymorphism of glutathione S-transferase Omega gene: association with risk of childhood acute lymphoblastic leukemia. J. Cancer Res. Clin. Oncol. 135, 673-678.
    • (2009) J. Cancer Res. Clin. Oncol. , vol.135 , pp. 673-678
    • Pongstaporn, W.1    Pakakasama, S.2    Sanguansin, S.3    Hongeng, S.4    Petmitr, S.5
  • 78
    • 22544436117 scopus 로고    scopus 로고
    • 7-Nitro-2,1,3-benzoxadiazole derivatives, a new class of suicide inhibitors for glutathione s-transferases
    • Ricci, G., De Maria, F., Antonini, G., Turella, P., Bullo, A., Stella, L., Filomeni, G., and Caccuri, A. M. (2005). 7-Nitro-2,1,3-benzoxadiazole derivatives, a new class of suicide inhibitors for glutathione s-transferases. J. Biol. Chem. 280, 26397-26405.
    • (2005) J. Biol. Chem. , vol.280 , pp. 26397-26405
    • Ricci, G.1    De Maria, F.2    Antonini, G.3    Turella, P.4    Bullo, A.5    Stella, L.6    Filomeni, G.7    Caccuri, A.M.8
  • 79
    • 1942521481 scopus 로고    scopus 로고
    • Modelling and bioinformatics studies of the human Kappa-class glutathione transferase predict a novel third glutathione transferase family with similarity to prokaryotic 2-hydroxychromene-2-carboxylate isomerases
    • Robinson, A., Huttley, G. A., Booth, H. S., and Board, P. G. (2004). Modelling and bioinformatics studies of the human Kappa-class glutathione transferase predict a novel third glutathione transferase family with similarity to prokaryotic 2-hydroxychromene-2-carboxylate isomerases. Biochem. J. 379, 541-552.
    • (2004) Biochem. J. , vol.379 , pp. 541-552
    • Robinson, A.1    Huttley, G.A.2    Booth, H.S.3    Board, P.G.4
  • 80
    • 33751115477 scopus 로고    scopus 로고
    • Human GSTA-1 reduces c-Jun N-terminal kinase signaling and apoptosis in Caco-2 cells
    • Romero, L., Andrews, K., Ng, L., O'Rourke, K., Maslen, A., and Kirby, G. (2006). Human GSTA-1 reduces c-Jun N-terminal kinase signaling and apoptosis in Caco-2 cells. Biochem. J. 400, 135-141.
    • (2006) Biochem. J. , vol.400 , pp. 135-141
    • Romero, L.1    Andrews, K.2    Ng, L.3    O'Rourke, K.4    Maslen, A.5    Kirby, G.6
  • 81
    • 73449146255 scopus 로고    scopus 로고
    • Enzymes as useful tools and potential targets in cancer chemotherapy
    • Ruzza, P., and Quintieri, L. (2009). Enzymes as useful tools and potential targets in cancer chemotherapy. Anticancer Agents Med. Chem. 9, 716.
    • (2009) Anticancer Agents Med. Chem. , vol.9 , pp. 716
    • Ruzza, P.1    Quintieri, L.2
  • 83
    • 0028099650 scopus 로고
    • P-glycoprotein and glutathione S-transferase pi in childhood acute lymphoblastic leukaemia
    • Sauerbrey, A., Zintl, F., and Volm, M. (1994). P-glycoprotein and glutathione S-transferase pi in childhood acute lymphoblastic leukaemia. Br. J. Cancer 70, 1144-1149.
    • (1994) Br. J. Cancer , vol.70 , pp. 1144-1149
    • Sauerbrey, A.1    Zintl, F.2    Volm, M.3
  • 85
    • 79957814731 scopus 로고    scopus 로고
    • Role of MGST1 in reactive intermediate-induced injury
    • Schaffert, C. S. (2011). Role of MGST1 in reactive intermediate-induced injury. World J. Gastroenterol. 17, 2552-2557.
    • (2011) World J. Gastroenterol. , vol.17 , pp. 2552-2557
    • Schaffert, C.S.1
  • 87
    • 75449102372 scopus 로고    scopus 로고
    • Inhibition of glutathione-s-transferase as a treatment strategy for multidrug resistance in childhood rhabdomyosarcoma
    • Seitz, G., Bonin, M., Fuchs, J., Poths, S., Ruck, P., Warmann, S. W., and Armeanu-Ebinger, S. (2010). Inhibition of glutathione-s-transferase as a treatment strategy for multidrug resistance in childhood rhabdomyosarcoma. Int. J. Oncol. 36, 491-500.
    • (2010) Int. J. Oncol. , vol.36 , pp. 491-500
    • Seitz, G.1    Bonin, M.2    Fuchs, J.3    Poths, S.4    Ruck, P.5    Warmann, S.W.6    Armeanu-Ebinger, S.7
  • 88
    • 33745817069 scopus 로고    scopus 로고
    • Antitumor activity of JS-K [O2-(2,4-dinitrophenyl) 1-[(4-ethoxycarbonyl)piperazin-1-yl]diazen-1-ium-1,2-diolate] and related O2-aryl diazeniumdiolates in vitro and in vivo
    • Shami, P. J., Saavedra, J. E., Bonifant, C. L., Chu, J., Udupi, V., Malaviya, S., Carr, B. I., Kar, S., Wang, M., Jia, L., Ji, X., and Keefer, L. K. (2006). Antitumor activity of JS-K [O2-(2,4-dinitrophenyl) 1-[(4-ethoxycarbonyl)piperazin-1-yl]diazen-1-ium-1,2-diolate] and related O2-aryl diazeniumdiolates in vitro and in vivo. J. Med. Chem. 49, 4356-4366.
    • (2006) J. Med. Chem. , vol.49 , pp. 4356-4366
    • Shami, P.J.1    Saavedra, J.E.2    Bonifant, C.L.3    Chu, J.4    Udupi, V.5    Malaviya, S.6    Carr, B.I.7    Kar, S.8    Wang, M.9    Jia, L.10    Ji, X.11    Keefer, L.K.12
  • 89
    • 0030778937 scopus 로고    scopus 로고
    • Evidence that human class theta glutathione S-transferase T1-1 can catalyse the activation of dichloromethane, a liver and lung carcinogen in the mouse. Comparison of the tissue distribution of GSTT1 with that of classes alpha, mu and pi GST in human
    • Sherratt, P. J., Pulford, D. J., Harrison, D. J., Green, T., and Hayes, J. D. (1997). Evidence that human class theta glutathione S-transferase T1-1 can catalyse the activation of dichloromethane, a liver and lung carcinogen in the mouse. Comparison of the tissue distribution of GSTT1 with that of classes alpha, mu and pi GST in human. Biochem. J. 326, 837-846.
    • (1997) Biochem. J. , vol.326 , pp. 837-846
    • Sherratt, P.J.1    Pulford, D.J.2    Harrison, D.J.3    Green, T.4    Hayes, J.D.5
  • 90
    • 33646366123 scopus 로고    scopus 로고
    • Expression profiling of EWS/FLI identifies NKX2.2 as a critical target gene in Ewing's sarcoma
    • Smith, R., Owen, L. A., Trem, D. J., Wong, J. S., Whangbo, J. S., Golub, T. R., and Lessnick, S. L. (2006). Expression profiling of EWS/FLI identifies NKX2.2 as a critical target gene in Ewing's sarcoma. Cancer Cell 9, 405-416.
    • (2006) Cancer Cell , vol.9 , pp. 405-416
    • Smith, R.1    Owen, L.A.2    Trem, D.J.3    Wong, J.S.4    Whangbo, J.S.5    Golub, T.R.6    Lessnick, S.L.7
  • 91
    • 0034651551 scopus 로고    scopus 로고
    • Polymorphisms within glutathione S-transferase genes (GSTM1, GSTT1, GSTP1) and risk of relapse in childhood B-cell precursor acute lymphoblastic leukemia: a case-control study
    • Stanulla, M., Schrappe, M., Brechlin, A. M., Zimmermann, M., and Welte, K. (2000). Polymorphisms within glutathione S-transferase genes (GSTM1, GSTT1, GSTP1) and risk of relapse in childhood B-cell precursor acute lymphoblastic leukemia: a case-control study. Blood 95, 1222-1228.
    • (2000) Blood , vol.95 , pp. 1222-1228
    • Stanulla, M.1    Schrappe, M.2    Brechlin, A.M.3    Zimmermann, M.4    Welte, K.5
  • 93
    • 0345686727 scopus 로고    scopus 로고
    • Impact of glutathione S-transferase gene deletion on early relapse in childhood B-precursor acute lymphoblastic leukemia
    • Takanashi, M., Morimoto, A., Yagi, T., Kuriyama, K., Kano, G., Imamura, T., Hibi, S., Todo, S., and Imashuku, S. (2003). Impact of glutathione S-transferase gene deletion on early relapse in childhood B-precursor acute lymphoblastic leukemia. Haematologica 88, 1238-1244.
    • (2003) Haematologica , vol.88 , pp. 1238-1244
    • Takanashi, M.1    Morimoto, A.2    Yagi, T.3    Kuriyama, K.4    Kano, G.5    Imamura, T.6    Hibi, S.7    Todo, S.8    Imashuku, S.9
  • 94
    • 0029853099 scopus 로고    scopus 로고
    • Mutagenesis of the active site of the human Theta-class glutathione transferase GSTT2-2: catalysis with different substrates involves different residues
    • Tan, K. L., Chelyanayagam, G., Parker, M. W., and Board, P. G. (1996). Mutagenesis of the active site of the human Theta-class glutathione transferase GSTT2-2: catalysis with different substrates involves different residues. Biochem. J. 319, 315-321.
    • (1996) Biochem. J. , vol.319 , pp. 315-321
    • Tan, K.L.1    Chelyanayagam, G.2    Parker, M.W.3    Board, P.G.4
  • 96
    • 0031558238 scopus 로고    scopus 로고
    • Inhibitors of glutathione S-transferases as therapeutic agents
    • Tew, K. D., Dutta, S., and Schultz, M. (1997). Inhibitors of glutathione S-transferases as therapeutic agents. Adv. Drug Deliv. Rev. 26, 91-104.
    • (1997) Adv. Drug Deliv. Rev. , vol.26 , pp. 91-104
    • Tew, K.D.1    Dutta, S.2    Schultz, M.3
  • 97
    • 79959362325 scopus 로고    scopus 로고
    • The role of glutathione s-transferase P in signaling pathways and s-glutathionylation in cancer
    • Tew, K. D., Manevich, Y., Grek, C., Xiong, Y., Uys, J., and Townsend, D. M. (2011). The role of glutathione s-transferase P in signaling pathways and s-glutathionylation in cancer. Free Radic. Biol. Med. 51, 299-313.
    • (2011) Free Radic. Biol. Med. , vol.51 , pp. 299-313
    • Tew, K.D.1    Manevich, Y.2    Grek, C.3    Xiong, Y.4    Uys, J.5    Townsend, D.M.6
  • 98
    • 0029895281 scopus 로고    scopus 로고
    • Glutathione-associated enzymes in the human cell lines of the National Cancer Institute Drug Screening Program
    • Tew, K. D., Monks, A., Barone, L., Rosser, D., Akerman, G., Montali, J. A., Wheatley, J. B., and Schmidt, D. E. (1996). Glutathione-associated enzymes in the human cell lines of the National Cancer Institute Drug Screening Program. Mol. Pharmacol. 50, 149-159.
    • (1996) Mol. Pharmacol. , vol.50 , pp. 149-159
    • Tew, K.D.1    Monks, A.2    Barone, L.3    Rosser, D.4    Akerman, G.5    Montali, J.A.6    Wheatley, J.B.7    Schmidt, D.E.8
  • 100
    • 33750570283 scopus 로고    scopus 로고
    • Caveolin-1 (CAV1) is a target of EWS/FLI-1 and a key determinant of the oncogenic phenotype and tumorigenicity of Ewing's sarcoma cells
    • Tirado, O. M., Mateo-Lozano, S., Villar, J., Dettin, L. E., Llort, A., Gallego, S., Ban, J., Kovar, H., and Notario, V. (2006). Caveolin-1 (CAV1) is a target of EWS/FLI-1 and a key determinant of the oncogenic phenotype and tumorigenicity of Ewing's sarcoma cells. Cancer Res. 66, 9937-9947.
    • (2006) Cancer Res. , vol.66 , pp. 9937-9947
    • Tirado, O.M.1    Mateo-Lozano, S.2    Villar, J.3    Dettin, L.E.4    Llort, A.5    Gallego, S.6    Ban, J.7    Kovar, H.8    Notario, V.9
  • 101
    • 0032522741 scopus 로고    scopus 로고
    • Glutathione transferase zeta catalyses the oxygenation of the carcinogen dichloroacetic acid to glyoxylic acid
    • Tong, Z., Board, P. G., and Anders, M. W. (1998a). Glutathione transferase zeta catalyses the oxygenation of the carcinogen dichloroacetic acid to glyoxylic acid. Biochem. J. 331, 371-374.
    • (1998) Biochem. J. , vol.331 , pp. 371-374
    • Tong, Z.1    Board, P.G.2    Anders, M.W.3
  • 102
    • 0031741776 scopus 로고    scopus 로고
    • Glutathione transferase zeta-catalyzed biotransformation of dichloroacetic acid and other a-haloacids
    • Tong, Z., Board, P. G., and Anders, M. W. (1998b). Glutathione transferase zeta-catalyzed biotransformation of dichloroacetic acid and other a-haloacids. Chem. Res. Toxicol. 11, 1332-1338.
    • (1998) Chem. Res. Toxicol. , vol.11 , pp. 1332-1338
    • Tong, Z.1    Board, P.G.2    Anders, M.W.3
  • 103
    • 0642374221 scopus 로고    scopus 로고
    • The role of glutathione-s-transferase in anti-cancer drug resistance
    • Townsend, D. M., and Tew, K. D. (2003). The role of glutathione-s-transferase in anti-cancer drug resistance. Oncogene 22, 7369-7375.
    • (2003) Oncogene , vol.22 , pp. 7369-7375
    • Townsend, D.M.1    Tew, K.D.2
  • 106
    • 33747644390 scopus 로고    scopus 로고
    • A strong glutathione s-transferase inhibitor overcomes the P-glycoprotein-mediated resistance in tumor cells: NBDHEX triggers a caspase-dependent apoptosis in MDR1-expressing leukemia cells
    • Turella, P., Filomeni, G., Dupuis, M. L., Ciriolo, M. R., Molinari, A., De Maria, F., Tombesi, M., Cianfriglia, M., Federici, G., Ricci, G., and Caccuri, A. M. (2006). A strong glutathione s-transferase inhibitor overcomes the P-glycoprotein-mediated resistance in tumor cells: NBDHEX triggers a caspase-dependent apoptosis in MDR1-expressing leukemia cells. J. Biol. Chem. 281, 23725-23732.
    • (2006) J. Biol. Chem. , vol.281 , pp. 23725-23732
    • Turella, P.1    Filomeni, G.2    Dupuis, M.L.3    Ciriolo, M.R.4    Molinari, A.5    De Maria, F.6    Tombesi, M.7    Cianfriglia, M.8    Federici, G.9    Ricci, G.10    Caccuri, A.M.11
  • 107
    • 70449107252 scopus 로고    scopus 로고
    • Redox-directed cancer therapeutics: molecular mechanisms and opportunities
    • Wondrak, G. T. (2009). Redox-directed cancer therapeutics: molecular mechanisms and opportunities. Antioxid. Redox Signal. 11, 3013-3069.
    • (2009) Antioxid. Redox Signal. , vol.11 , pp. 3013-3069
    • Wondrak, G.T.1
  • 108
    • 33748919803 scopus 로고    scopus 로고
    • Human glutathion s-transferase P1-1 interacts with TRAF2 and regulates TRAF2-ASK1 signals
    • Wu, Y., Fan, Y., Xue, B., Luo, L., Shen, J., Zhang, S., Jiang, Y., and Yin, Z. (2006). Human glutathion s-transferase P1-1 interacts with TRAF2 and regulates TRAF2-ASK1 signals. Oncogene 25, 5787-5800.
    • (2006) Oncogene , vol.25 , pp. 5787-5800
    • Wu, Y.1    Fan, Y.2    Xue, B.3    Luo, L.4    Shen, J.5    Zhang, S.6    Jiang, Y.7    Yin, Z.8
  • 109
    • 0025778695 scopus 로고
    • Glutathione S-transferase mu locus: use of genotyping and phenotyping assays to assess association with lung cancer susceptibility
    • Zhong, S., Howie, A. F., Ketterer, B., Taylor, J., Hayes, J. D., Beckett, G. J., Wathen, C. G., Wolf, C. R., and Spurr, N. K. (1991). Glutathione S-transferase mu locus: use of genotyping and phenotyping assays to assess association with lung cancer susceptibility. Carcinogenesis 12, 1533-1537.
    • (1991) Carcinogenesis , vol.12 , pp. 1533-1537
    • Zhong, S.1    Howie, A.F.2    Ketterer, B.3    Taylor, J.4    Hayes, J.D.5    Beckett, G.J.6    Wathen, C.G.7    Wolf, C.R.8    Spurr, N.K.9
  • 110
    • 4744351395 scopus 로고    scopus 로고
    • Polymorphism within the glutathione S-transferase P1 gene is associated with increased susceptibility to childhood malignant diseases
    • Zielinska, E., Zubowska, M., and Bodalski, J. (2004). Polymorphism within the glutathione S-transferase P1 gene is associated with increased susceptibility to childhood malignant diseases. Pediatr. Blood Cancer 43, 552-559.
    • (2004) Pediatr. Blood Cancer , vol.43 , pp. 552-559
    • Zielinska, E.1    Zubowska, M.2    Bodalski, J.3


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