Effects of bioreactor hydrodynamics on the physiology of Streptomyces

Bioprocess and Biosystems Engineering

Volumn 36, Issue 3, 2013, Pages 259-272

  Olmos, E ^a,b   Mehmood, N ^a,b   Haj Husein, L ^a,b   Goergen, J L ^a,b   Fick, M ^a,b   Delaunay, S ^a,b  

^a CNRS   (France)

^b UNIVERSITÉ DE LORRAINE   (France)

Author keywords

Antibiotic production; Bioreactor; Hydrodynamics; Mass transfer; Streptomyces

Indexed keywords

ANTIBIOTIC PRODUCTION; BIOREACTOR HYDRODYNAMICS; FILAMENTOUS BACTERIA; INTRACELLULAR SIGNALS; MICROBIAL RESPONSE; OPERATING CONDITION; PHYSIOLOGICAL RESPONSE; STREPTOMYCES;

ANTIBIOTICS; BIOCONVERSION; BIOREACTORS; HYDRODYNAMICS; MASS TRANSFER; PHYSIOLOGICAL MODELS; PHYSIOLOGY;

BACTERIA;

CAPREOMYCIN; CEPHALOSPORIN C; CEPHAMYCIN C; CHLORTETRACYCLINE; CLAVULANIC ACID; NATAMYCIN; NEOMYCIN; PRISTINAMYCIN; TYLOSIN; VIRGINIAMYCIN;

AGITATION; BACTERIAL GROWTH; BACTERIUM CULTURE; BIOREACTOR; BIOREACTOR DESIGN; CELL DAMAGE; DRUG MANUFACTURE; ENZYME ACTIVITY; FLOW RATE; GAS FLOW; GRAM POSITIVE BACTERIUM; HYDRODYNAMICS; MICROBIAL BIOMASS; NONHUMAN; NUTRIENT CONCENTRATION; NUTRIENT LIMITATION; OXYGEN DIFFUSION; PHYSIOLOGICAL PROCESS; PRIORITY JOURNAL; REVIEW; SCALE UP; STREPTOMYCES; STREPTOMYCES AUREOFACIENS; STREPTOMYCES AVERMITILIS; STREPTOMYCES CLAVULIGERUS; STREPTOMYCES FRADIAE; STREPTOMYCES GLOBISPORUS; STREPTOMYCES TENDAE; STREPTOMYCES VIRGINIAE; SUBMERGED FERMENTATION; TURBULENT FLOW;

ANTI-BACTERIAL AGENTS; BIOREACTORS; BIOTECHNOLOGY; FERMENTATION; HYDRODYNAMICS; OXYGEN; PRISTINAMYCIN; RHEOLOGY; STREPTOMYCES; STRESS, MECHANICAL;

STREPTOMYCES;

EID: 84879575408     PISSN: 16157591     EISSN: 16157605     Source Type: Journal    
DOI: 10.1007/s00449-012-0794-1     Document Type: Review

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