The effect of dissolved oxygen concentration control on cell growth and antibiotic retamycin production in Streptomyces olindensis So20 fermentations

Brazilian Journal of Chemical Engineering

Volumn 21, Issue 2, 2004, Pages 185-192

  Martins, R A ^a   Guimaraes L M ^b   Pamboukian, C R ^b   Tonso, A ^a   Facciotti, M C R ^a   Schmidell, W ^b  

^a UNIVERSITY OF SÃO PAULO   (Brazil)

^b NONE

Author keywords

Antibiotic; Oxygen transfer; Retamycin; Streptomyces

Indexed keywords

ANTIBIOTICS; BIOREACTORS; CELL CULTURE; DISSOLVED OXYGEN SENSORS; FERMENTATION; GLUCOSE; MICROORGANISMS; OXYGEN;

OXYGEN TRANSFER; RETAMYCIN; STREPTOMYCES;

CELLS;

EID: 1842481333     PISSN: 01046632     EISSN: None     Source Type: Journal    
DOI: 10.1590/S0104-66322004000200007     Document Type: Conference Paper

References (10)

1. Asfora, J.J., Santana, C.F. and Lima, O.G., Primeiras Observações com o Uso da Retamicina em Pacientes Portadores de Leucemias Agudas, Revista do Institute de Antibióticos, vol. 12, pp. 89-99 (1972).
2. Chen, H.C. and Wilde, F., The Effect of Dissolved Oxygen and Aeration Rate on Antibiotic Production of Streptomyces fradiae, Biotechnology and Bioengineering, vol. 37, pp. 591-595 (1990).
3. Cotias, C.T., Santana, C.F., Pinto, K.V., Filho, A.M., Lacerda, A.and Moreira, L.C., Estudos Farmacológicos e Hispatológicos da Retamicina (Complexo), Revista do Institute de Antibióticos, vol. 11, pp. 51-59 (1971).
4. Hopwood, D.A., Bibb, M.J., Chater, K.F., Kieser, T., Bruton, C.J., Kieser, H.M., Lydiate, J., Smith, C.P., Ward, J.M. and Scrempf, H., Genetic Manipulation of Streptomyces: A Llaboratory Manual, Norwich, The John Innes Foundation, England (1985).
5. 2 on the Fermentative Production of Gallidermin by Staphylococcus gallinarum, Biotechnology Letters, vol. 19, pp. 1063-1065 (1997).
6. Martins, R.A., Transferência de Oxigênio e Respiração Microbiana em Cultivos de Streptomyces olindensis So20, Visando à Produção do Antibiótico Retamicina, Master's Thesis, Escola Politécnica, Universidade de São Paulo, São Paulo, Brazil, 157p (2001).
7. Schmidell, W., Lima, U.A., Aquarone, E. and Borzani, W., Biotecnologia Industrial, pp. 299-308 (2001) (Coleção Biotecnologia, vol. 2).
8. Schmidell, W., Lima, U.A., Aquarone, E. and Borzani, W., Biotecnologia Industrial, pp. 299-308 (2001) (Coleção Biotecnologia, vol. 2).
9. Shioya, S., Morikawa, M., Kajihara, Y. and Shimizu, H., Optimization of Agitation and Aeration Conditions for Maximum Virginiamycin Production, Applied Microbiology and Biotechnology, vol. 51, pp. 164-169 (1999).
10. Yegneswaran, P.K., Gray, M.R. and Thompson, B.G., Effect of Dissolved Oxygen Control on Growth and Antibiotic Production in Streptomyces clavuligerus Fermentations, Biotechnology Progress, vol .7, pp. 246-250 (1991).