Influence of dissolved oxygen and shear conditions on clavulanic acid production by Streptomyces clavuligerus

Bioprocess and Biosystems Engineering

Volumn 27, Issue 2, 2005, Pages 99-104

  Rosa, J C ^a   Neto, A Baptista ^a   Hokka, C O ^a   Badino, A C ^a  

^a FEDERAL UNIVERSITY OF SÃO CARLOS   (Brazil)

Author keywords

Clavulanic acid; Dissolved oxygen; Mass transfer; Shear rate; Streptomyces clavuligerus

Indexed keywords

BACTERIA; ENZYME INHIBITION; FERMENTATION; OXYGEN; SPEED CONTROL;

Β-LACTAMASE; AIR FLOW; AIR SATURATION; CLAVULANIC ACID (CA);

CARBOXYLIC ACIDS;

CLAVULANIC ACID; DISSOLVED OXYGEN;

AEROBIC FERMENTATION; AEROBIC REACTOR; AIRFLOW; ARTICLE; BACTERIUM CULTURE; CONTROLLED STUDY; NONHUMAN; OXYGEN CONSUMPTION; OXYGENATION; PRIORITY JOURNAL; SHEAR RATE; STREPTOMYCES CLAVULIGERUS;

BIOREACTORS; CELL CULTURE TECHNIQUES; CLAVULANIC ACID; CULTURE MEDIA; GLYCEROL; MECHANOTRANSDUCTION, CELLULAR; OXYGEN; RHEOLOGY; SHEAR STRENGTH; SOLUBILITY; STREPTOMYCES;

EID: 17744399924     PISSN: 16157591     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00449-004-0386-9     Document Type: Article

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