Cytotoxicity and QSAR study of (thio)ureas derived from phenylalkylamines and pyridylalkylamines

Medicinal Chemistry Research

Volumn 22, Issue 8, 2013, Pages 4016-4029

  Pingaew, Ratchanok ^a   Tongraung, Pan ^a   Worachartcheewan, Apilak ^b   Nantasenamat, Chanin ^b   Prachayasittikul, Supaluk ^b   Ruchirawat, Somsak ^c   Prachayasittikul, Virapong ^b  

^a SRINAKHARINWIROT UNIVERSITY   (Thailand)

^b MAHIDOL UNIVERSITY   (Thailand)

^c Toxicology and Management of Chemicals   (Thailand)

Author keywords

Anticancer; Multiple linear regression; QSAR; Urea

Indexed keywords

1 (3,4 DIMETHOXYPHENETHYL) 3 (4 CHLOROPHENYL)THIOUREA; 1 (3,4 DIMETHOXYPHENETHYL) 3 (4 CHLOROPHENYL)UREA; 1 (3,4 DIMETHOXYPHENETHYL) 3 (4 NITROPHENYL)THIOUREA; 1 (4 CHLOROPHENYL) 3 (2 (PYRIDIN 2 YL)ETHYL)UREA; 1 (4 CHLOROPHENYL) 3 (PYRIDIN 2 YLMETHYL)THIOUREA; 1 (4 CHLOROPHENYL) 3 (PYRIDIN 2 YLMETHYL)UREA; 1 (4 CHLOROPHENYL) 3 PHENETHYLTHIOUREA; 1 (4 CHLOROPHENYL) 3 PHENETHYLUREA; 1 (4 NITROPHENYL) 3 (2 (PYRIDIN 2 YL)ETHYL)THIOUREA; 1 (4 NITROPHENYL) 3 (PYRIDIN 2 YLMETHYL)THIOUREA; 1 (4 NITROPHENYL) 3 PHENETHYLTHIOUREA; 1,1' (1,3 PHENYLENEBIS(METHYLENE))BIS(3 (4 CHLOROPHENYL)THIOUREA); 1,1' (1,3 PHENYLENEBIS(METHYLENE))BIS(3 (4 NITROPHENYL)THIOUREA; 1,1' (1,3 PHENYLENEBIS(METHYLENE))BIS(3 (4CHLOROPHENYL)THIOUREA); 2 (2 PYRIDYL)ETHYLAMINE; 2 PICOLYLAMINE DERIVATIVE; ALIPHATIC AMINE; ANTINEOPLASTIC AGENT; DOXORUBICIN; ETOPOSIDE; HOMOVERATYLAMINE DERIVATIVE; PHENYLALKYLAMINE; THIOUREA DERIVATIVE; UNCLASSIFIED DRUG; XYLYLENEDIAMINE DERIVATIVE;

ARTICLE; CANCER CELL CULTURE; CARBON NUCLEAR MAGNETIC RESONANCE; CELL STRAIN HEPG2; CONTROLLED STUDY; CYTOTOXICITY; DRUG POTENCY; DRUG SYNTHESIS; HUMAN; HUMAN CELL; IONIZATION; PROTON NUCLEAR MAGNETIC RESONANCE; QUANTITATIVE STRUCTURE ACTIVITY RELATION; QUANTUM CHEMISTRY;

EID: 84879501042     PISSN: 10542523     EISSN: 15548120     Source Type: Journal    
DOI: 10.1007/s00044-012-0402-6     Document Type: Article

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