3-(Iodoacetamido)-benzoylurea: A novel cancericidal tubulin ligand that inhibits microtubule polymerization, phosphorylates bcl-2, and induces apoptosis in tumor cells

Cancer Research

Volumn 58, Issue 23, 1998, Pages 5389-5395

  Jiang, Jian Dong ^a   Davis, Ashley S ^b   Middleton, Kim ^b   Ling, Yi He ^c   Perez Soler, Roman ^c   Holland, James F ^a   Bekesi, J George ^a  

^a MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^b Cytoskeleton Inc   (United States)

^c NEW YORK UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

3 (IODOACETAMIDO)BENZOYLUREA; ANTINEOPLASTIC AGENT; COLCHICINE; GUANOSINE DIPHOSPHATE; GUANOSINE TRIPHOSPHATE; ONCOPROTEIN; PACLITAXEL; PROTEIN BCL 2; PROTEIN SUBUNIT; TUBULIN; UNCLASSIFIED DRUG; VINBLASTINE;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CANCER CHEMOTHERAPY; CONTROLLED STUDY; DRUG CYTOTOXICITY; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE; METAPHASE; MICROTUBULE ASSEMBLY; MOLECULAR WEIGHT; POLYMERIZATION; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SOLID TUMOR;

ANTINEOPLASTIC AGENTS; APOPTOSIS; BINDING SITES; BINDING, COMPETITIVE; CELL CYCLE; DIMERIZATION; HUMANS; LIGANDS; MICROTUBULES; MITOSIS; MITOTIC SPINDLE APPARATUS; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-BCL-2; TUBULIN; TUMOR CELLS, CULTURED;

EID: 0032403865     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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