-
1
-
-
0027987849
-
Randomised trial of cholesterol lowering in 4444 patients with coronary heart disease: The Scandinavian Simvastatin Survival Study (4S)
-
Randomised trial of cholesterol lowering in 4444 patients with coronary heart disease: The Scandinavian Simvastatin Survival Study (4S). Lancet 344: 1383-1389.
-
Lancet
, vol.344
, pp. 1383-1389
-
-
-
2
-
-
0032487931
-
Prevention of cardiovascular events and death with pravastatin in patients with coronary heart disease and a broad range of initial cholesterol levels
-
The Long-Term Intervention with Pravastatin in Ischaemic Disease (LIPID) Study Group
-
Prevention of cardiovascular events and death with pravastatin in patients with coronary heart disease and a broad range of initial cholesterol levels. The Long-Term Intervention with Pravastatin in Ischaemic Disease (LIPID) Study Group. N Engl J Med 339:1349-1357.
-
N Engl J Med
, vol.339
, pp. 1349-1357
-
-
-
3
-
-
77649291952
-
Pravastatin counteracts angiotensin II-induced upregulation and activation of NADPH oxidase at plasma membrane of human endothelial cells
-
Alvarez E, Rodino-Janeiro BK, Ucieda-Somoza R, and González- Juanatey JR (2010) Pravastatin counteracts angiotensin II-induced upregulation and activation of NADPH oxidase at plasma membrane of human endothelial cells. J Cardiovasc Pharmacol 55:203-212.
-
(2010)
J Cardiovasc Pharmacol
, vol.55
, pp. 203-212
-
-
Alvarez, E.1
Rodino-Janeiro, B.K.2
Ucieda-Somoza, R.3
González-Juanatey, J.R.4
-
4
-
-
50649105705
-
Effects of pravastatin on obesity, diabetes, and adiponectin in diet-induced obese mice
-
Araki K, Masaki T, Katsuragi I, Kakuma T, and Yoshimatsu H (2008) Effects of pravastatin on obesity, diabetes, and adiponectin in diet-induced obese mice. Obesity (Silver Spring) 16:2068-2073.
-
(2008)
Obesity (Silver Spring
, vol.16
, pp. 2068-2073
-
-
Araki, K.1
Masaki, T.2
Katsuragi, I.3
Kakuma, T.4
Yoshimatsu, H.5
-
5
-
-
77649247134
-
Activation of membrane NADPH oxidase associated with lysosome-targeted acid sphingomyelinase in coronary endothelial cells
-
Bao JX, Jin S, Zhang F, Wang ZC, Li N, and Li PL (2010a) Activation of membrane NADPH oxidase associated with lysosome-targeted acid sphingomyelinase in coronary endothelial cells. Antioxid Redox Signal 12:703-712.
-
(2010)
Antioxid Redox Signal
, vol.12
, pp. 703-712
-
-
Bao, J.X.1
Jin, S.2
Zhang, F.3
Wang, Z.C.4
Li, N.5
Li, P.L.6
-
6
-
-
77749264336
-
Triggering role of acid sphingomyelinase in endothelial lysosome-membrane fusion and dysfunction in coronary arteries
-
Bao JX, Xia M, Poklis JL, Han WQ, Brimson C, and Li PL (2010b) Triggering role of acid sphingomyelinase in endothelial lysosome-membrane fusion and dysfunction in coronary arteries. Am J Physiol Heart Circ Physiol 298:H992-H1002.
-
(2010)
Am J Physiol Heart Circ Physiol
, vol.298
-
-
Bao, J.X.1
Xia, M.2
Poklis, J.L.3
Han, W.Q.4
Brimson, C.5
Li, P.L.6
-
7
-
-
77952216684
-
Atorvastatin inhibits homocysteine-induced dysfunction and apoptosis in endothelial progenitor cells
-
Bao XM, Wu CF, and Lu GP (2010c) Atorvastatin inhibits homocysteine-induced dysfunction and apoptosis in endothelial progenitor cells. Acta Pharmacol Sin 31: 476-484.
-
(2010)
Acta Pharmacol Sin
, vol.31
, pp. 476-484
-
-
Bao, X.M.1
Wu, C.F.2
Lu, G.P.3
-
8
-
-
0036847070
-
Simvastatin promotes atherosclerotic plaque stability in ApoE-deficient mice independently of lipid lowering
-
DOI 10.1161/01.ATV.0000036081.01231.16
-
Bea F, Blessing E, Bennett B, Levitz M, Wallace EP, and Rosenfeld ME (2002) Simvastatin promotes atherosclerotic plaque stability in apoE-deficient mice independently of lipid lowering. Arterioscler Thromb Vasc Biol 22:1832-1837. (Pubitemid 35315769)
-
(2002)
Arteriosclerosis, Thrombosis, and Vascular Biology
, vol.22
, Issue.11
, pp. 1832-1837
-
-
Bea, F.1
Blessing, E.2
Bennett, B.3
Levitz, M.4
Wallace, E.P.5
Rosenfeld, M.E.6
-
9
-
-
67649837051
-
Atorvastatin prevents angiotensin II-induced vascular remodeling and oxidative stress
-
Briones AM, Rodríguez-Criado N, Hernanz R, García-Redondo AB, Rodrigues-Díez RR, Alonso MJ, Egido J, Ruiz-Ortega M, and Salaices M (2009) Atorvastatin prevents angiotensin II-induced vascular remodeling and oxidative stress. Hypertension 54:142-149.
-
(2009)
Hypertension
, vol.54
, pp. 142-149
-
-
Briones, A.M.1
Rodríguez-Criado, N.2
Hernanz, R.3
García-Redondo, A.B.4
Rodrigues-Díez, R.R.5
Alonso, M.J.6
Egido, J.7
Ruiz-Ortega, M.8
Salaices, M.9
-
10
-
-
79957899628
-
Mechanisms for the anti-inflammatory effects of statins
-
Bu DX, Griffin G, and Lichtman AH (2011) Mechanisms for the anti-inflammatory effects of statins. Curr Opin Lipidol 22:165-170.
-
(2011)
Curr Opin Lipidol
, vol.22
, pp. 165-170
-
-
Bu, D.X.1
Griffin, G.2
Lichtman, A.H.3
-
11
-
-
34147182364
-
Resveratrol attenuates oxLDLstimulated NADPH oxidase activity and protects endothelial cells from oxidative functional damages
-
Chow SE, Hshu YC, Wang JS, and Chen JK (2007) Resveratrol attenuates oxLDLstimulated NADPH oxidase activity and protects endothelial cells from oxidative functional damages. J Appl Physiol 102:1520-1527.
-
(2007)
J Appl Physiol
, vol.102
, pp. 1520-1527
-
-
Chow, S.E.1
Hshu, Y.C.2
Wang, J.S.3
Chen, J.K.4
-
12
-
-
61549114350
-
Statins control oxidized LDLmediated histone modifications and gene expression in cultured human endothelial cells
-
Dje N'Guessan P, Riediger F, Vardarova K, Scharf S, Eitel J, Opitz B, Slevogt H, Weichert W, Hocke AC, and Schmeck B, et al. (2009) Statins control oxidized LDLmediated histone modifications and gene expression in cultured human endothelial cells. Arterioscler Thromb Vasc Biol 29:380-386.
-
(2009)
Arterioscler Thromb Vasc Biol
, vol.29
, pp. 380-386
-
-
Dje N'Guessan, P.1
Riediger, F.2
Vardarova, K.3
Scharf, S.4
Eitel, J.5
Opitz, B.6
Slevogt, H.7
Weichert, W.8
Hocke, A.C.9
Schmeck, B.10
-
13
-
-
11344277830
-
Statins for atherosclerosis-as good as it gets?
-
Ehrenstein MR, Jury EC, and Mauri C (2005) Statins for atherosclerosis-as good as it gets? N Engl J Med 352:73-75.
-
(2005)
N Engl J Med
, vol.352
, pp. 73-75
-
-
Ehrenstein, M.R.1
Jury, E.C.2
Mauri, C.3
-
14
-
-
0024972452
-
Animal safety and toxicology of simvastatin and related hydroxy-methylglutaryl-coenzyme A reductase inhibitors
-
Gerson RJ, MacDonald JS, Alberts AW, Kornbrust DJ, Majka JA, Stubbs RJ, and Bokelman DL (1989) Animal safety and toxicology of simvastatin and related hydroxy-methylglutaryl-coenzyme A reductase inhibitors. Am J Med 87 (4A): 28S-38S.
-
(1989)
Am J Med
, vol.87
, Issue.4 A
-
-
Gerson, R.J.1
MacDonald, J.S.2
Alberts, A.W.3
Kornbrust, D.J.4
Majka, J.A.5
Stubbs, R.J.6
Bokelman, D.L.7
-
15
-
-
33846639179
-
Statins and the vascular endothelial inflammatory response
-
DOI 10.1016/j.it.2006.12.003, PII S1471490606003498
-
Greenwood J and Mason JC (2007) Statins and the vascular endothelial inflammatory response. Trends Immunol 28:88-98. (Pubitemid 46178495)
-
(2007)
Trends in Immunology
, vol.28
, Issue.2
, pp. 88-98
-
-
Greenwood, J.1
Mason, J.C.2
-
16
-
-
0032559362
-
Rho GTpases and the actin cytoskeleton
-
DOI 10.1126/science.279.5350.509
-
Hall A (1998) Rho GTPases and the actin cytoskeleton. Science 279:509-514. (Pubitemid 28067271)
-
(1998)
Science
, vol.279
, Issue.5350
, pp. 509-514
-
-
Hall, A.1
-
17
-
-
0345532411
-
HMG-CoA reductase inhibitor increases GTP cyclohydrolase I mRNA and tetrahydrobiopterin in vascular endothelial cells
-
DOI 10.1161/01.ATV.0000054659.72231.A1
-
Hattori Y, Nakanishi N, Akimoto K, Yoshida M, and Kasai K (2003) HMGCoA reductase inhibitor increases GTP cyclohydrolase I mRNA and tetrahydrobiopterin in vascular endothelial cells. Arterioscler Thromb Vasc Biol 23: 176-182. (Pubitemid 36231925)
-
(2003)
Arteriosclerosis, Thrombosis, and Vascular Biology
, vol.23
, Issue.2
, pp. 176-182
-
-
Hattori, Y.1
Nakanishi, N.2
Akimoto, K.3
Yoshida, M.4
Kasai, K.5
-
18
-
-
37349010303
-
Adverse balance of nitric oxide/peroxynitrite in the dysfunctional endothelium can be reversed by statins
-
DOI 10.1097/FJC.0b013e31811f3fd0, PII 0000534420071000000006
-
Heeba G, Hassan MK, Khalifa M, and Malinski T (2007) Adverse balance of nitric oxide/peroxynitrite in the dysfunctional endothelium can be reversed by statins. J Cardiovasc Pharmacol 50:391-398. (Pubitemid 350303816)
-
(2007)
Journal of Cardiovascular Pharmacology
, vol.50
, Issue.4
, pp. 391-398
-
-
Heeba, G.1
Hassan, M.K.A.2
Khalifa, M.3
Malinski, T.4
-
19
-
-
33645872999
-
Lipoprotein oxidation in cardiovascular disease: Chief culprit or innocent bystander?
-
Heinecke JW (2006) Lipoprotein oxidation in cardiovascular disease: Chief culprit or innocent bystander? J Exp Med 203:813-816.
-
(2006)
J Exp Med
, vol.203
, pp. 813-816
-
-
Heinecke, J.W.1
-
20
-
-
60749131372
-
Statins in endothelial signaling and activation
-
Jacobson JR (2009) Statins in endothelial signaling and activation. Antioxid Redox Signal 11:811-821.
-
(2009)
Antioxid Redox Signal
, vol.11
, pp. 811-821
-
-
Jacobson, J.R.1
-
21
-
-
18844441159
-
A role for platelet-derived growth factor β-receptor in a newborn rat model of endothelin-mediated pulmonary vascular remodeling
-
DOI 10.1152/ajplung.00180.2004
-
Jankov RP, Kantores C, Belcastro R, Yi S, Ridsdale RA, Post M, and Tanswell AK (2005) A role for platelet-derived growth factor beta-receptor in a newborn rat model of endothelin-mediated pulmonary vascular remodeling. Am J Physiol Lung Cell Mol Physiol 288:L1162-L1170. (Pubitemid 40695443)
-
(2005)
American Journal of Physiology - Lung Cellular and Molecular Physiology
, vol.288
, Issue.6
-
-
Jankov, R.P.1
Kantores, C.2
Belcastro, R.3
Yi, S.4
Ridsdale, R.A.5
Post, M.6
Keith Tanswell, A.7
-
23
-
-
55449134163
-
Lysosomal targeting and trafficking of acid sphingomyelinase to lipid raft platforms in coronary endothelial cells
-
Jin S, Yi F, Zhang F, Poklis JL, and Li PL (2008a) Lysosomal targeting and trafficking of acid sphingomyelinase to lipid raft platforms in coronary endothelial cells. Arterioscler Thromb Vasc Biol 28:2056-2062.
-
(2008)
Arterioscler Thromb Vasc Biol
, vol.28
, pp. 2056-2062
-
-
Jin, S.1
Yi, F.2
Zhang, F.3
Poklis, J.L.4
Li, P.L.5
-
24
-
-
40749145747
-
Critical role of lipid raft redox signaling platforms in endostatin-induced coronary endothelial dysfunction
-
Jin S, Zhang Y, Yi F, and Li PL (2008b) Critical role of lipid raft redox signaling platforms in endostatin-induced coronary endothelial dysfunction. Arterioscler Thromb Vasc Biol 28:485-490.
-
(2008)
Arterioscler Thromb Vasc Biol
, vol.28
, pp. 485-490
-
-
Jin, S.1
Zhang, Y.2
Yi, F.3
Li, P.L.4
-
25
-
-
33646033422
-
Poloxamer 407 (P-407)-mediated reduction in the gene expression of ATP-binding-cassette transporter A1 may contribute to increased cholesterol in peripheral tissues of P-407-treated rats
-
Johnston TP, Jaye M, Webb CL, Krawiec JA, Alom-Ruiz SP, Sachs-Barrable K, and Wasan KM (2006) Poloxamer 407 (P-407)-mediated reduction in the gene expression of ATP-binding-cassette transporter A1 may contribute to increased cholesterol in peripheral tissues of P-407-treated rats. Eur J Pharmacol 536: 232-240.
-
(2006)
Eur J Pharmacol
, vol.536
, pp. 232-240
-
-
Johnston, T.P.1
Jaye, M.2
Webb, C.L.3
Krawiec, J.A.4
Alom-Ruiz, S.P.5
Sachs-Barrable, K.6
Wasan, K.M.7
-
26
-
-
15944384675
-
Statins: Immunomodulators for autoimmune rheumatic disease?
-
DOI 10.1191/0961203303lu2135oa
-
Jury EC and Ehrenstein MR (2005) Statins: Immunomodulators for autoimmune rheumatic disease? Lupus 14:192-196. (Pubitemid 40445582)
-
(2005)
Lupus
, vol.14
, Issue.3
, pp. 192-196
-
-
Jury, E.C.1
Ehrenstein, M.R.2
-
27
-
-
27644447314
-
Oxidized LDL, a critical factor in atherogenesis
-
DOI 10.1016/j.cardiores.2005.09.009, PII S0008636305004463
-
Li D and Mehta JL (2005) Oxidized LDL, a critical factor in atherogenesis. Cardiovasc Res 68:353-354. (Pubitemid 41566554)
-
(2005)
Cardiovascular Research
, vol.68
, Issue.3
, pp. 353-354
-
-
Li, D.1
Mehta, J.L.2
-
29
-
-
70450189795
-
Inflammation in atherosclerosis: From pathophysiology to practice
-
Leducq Transatlantic Network on Atherothrombosis
-
Libby P, Ridker PM, and Hansson GK; Leducq Transatlantic Network on Atherothrombosis (2009) Inflammation in atherosclerosis: From pathophysiology to practice. J Am Coll Cardiol 54:2129-2138.
-
(2009)
J Am Coll Cardiol
, vol.54
, pp. 2129-2138
-
-
Libby, P.1
Ridker, P.M.2
Hansson, G.K.3
-
30
-
-
2642533516
-
Effects of HMG-CoA reductase inhibitors on endothelial function: Role of microdomains and oxidative stress
-
Mason RP, Walter MF, and Jacob RF (2004) Effects of HMG-CoA reductase inhibitors on endothelial function: Role of microdomains and oxidative stress. Circulation 109 (21, Suppl 1)II34-II41. (Pubitemid 38724154)
-
(2004)
Circulation
, vol.109
, Issue.21 SUPPL.
-
-
Mason, R.P.1
Walter, M.F.2
Jacob, R.F.3
-
31
-
-
84863911000
-
Cholesterol-lowering drugs inhibit lectin-like oxidized low-density lipoprotein-1 receptor function by membrane raft disruption
-
Matarazzo S, Quitadamo MC, Mango R, Ciccone S, Novelli G, and Biocca S (2012) Cholesterol-lowering drugs inhibit lectin-like oxidized low-density lipoprotein-1 receptor function by membrane raft disruption. Mol Pharmacol 82:246-254.
-
(2012)
Mol Pharmacol
, vol.82
, pp. 246-254
-
-
Matarazzo, S.1
Quitadamo, M.C.2
Mango, R.3
Ciccone, S.4
Novelli, G.5
Biocca, S.6
-
32
-
-
0031693206
-
Apoptotic, non-apoptotic, and anti-apoptotic pathways of tumor necrosis factor signalling
-
DOI 10.1016/S0006-2952(98)00154-3, PII S0006295298001543
-
Natoli G, Costanzo A, Guido F, Moretti F, and Levrero M (1998) Apoptotic, nonapoptotic, and anti-apoptotic pathways of tumor necrosis factor signalling. Biochem Pharmacol 56:915-920. (Pubitemid 28454555)
-
(1998)
Biochemical Pharmacology
, vol.56
, Issue.8
, pp. 915-920
-
-
Natoli, G.1
Costanzo, A.2
Guido, F.3
Moretti, F.4
Levrero, M.5
-
34
-
-
49749108198
-
Pravastatin improves renal ischemia-reperfusion injury by inhibiting the mevalonate pathway
-
Sharyo S, Yokota-Ikeda N, Mori M, Kumagai K, Uchida K, Ito K, Burne-Taney MJ, Rabb H, and Ikeda M (2008) Pravastatin improves renal ischemia-reperfusion injury by inhibiting the mevalonate pathway. Kidney Int 74:577-584.
-
(2008)
Kidney Int
, vol.74
, pp. 577-584
-
-
Sharyo, S.1
Yokota-Ikeda, N.2
Mori, M.3
Kumagai, K.4
Uchida, K.5
Ito, K.6
Burne-Taney, M.J.7
Rabb, H.8
Ikeda, M.9
-
35
-
-
0037197722
-
Is the oxidative modification hypothesis relevant to human atherosclerosis? Do the antioxidant trials conducted to date refute the hypothesis?
-
DOI 10.1161/01.CIR.0000014762.06201.06
-
Steinberg D and Witztum JL (2002) Is the oxidative modification hypothesis relevant to human atherosclerosis? Do the antioxidant trials conducted to date refute the hypothesis? Circulation 105:2107-2111. (Pubitemid 34465275)
-
(2002)
Circulation
, vol.105
, Issue.17
, pp. 2107-2111
-
-
Steinberg, D.1
Witztum, J.L.2
-
36
-
-
33749019757
-
Simvastatin improves diabetes-induced coronary endothelial dysfunction
-
DOI 10.1124/jpet.106.106823
-
Tawfik HE, El-Remessy AB, Matragoon S, Ma G, Caldwell RB, and Caldwell RW (2006) Simvastatin improves diabetes-induced coronary endothelial dysfunction. J Pharmacol Exp Ther 319:386-395. (Pubitemid 44455146)
-
(2006)
Journal of Pharmacology and Experimental Therapeutics
, vol.319
, Issue.1
, pp. 386-395
-
-
Tawfik, H.E.1
El-Remessy, A.B.2
Matragoon, S.3
Ma, G.4
Caldwell, R.B.5
Caldwell, R.W.6
-
38
-
-
33847606920
-
A novel mechanism of action for statins against diabetes-induced oxidative stress
-
DOI 10.1007/s00125-007-0597-0
-
Vecchione C, Gentile MT, Aretini A, Marino G, Poulet R, Maffei A, Passarelli F, Landolfi A, Vasta A, and Lembo G (2007) A novel mechanism of action for statins against diabetes-induced oxidative stress. Diabetologia 50:874-880. (Pubitemid 46355833)
-
(2007)
Diabetologia
, vol.50
, Issue.4
, pp. 874-880
-
-
Vecchione, C.1
Gentile, M.T.2
Aretini, A.3
Marino, G.4
Poulet, R.5
Maffei, A.6
Passarelli, F.7
Landolfi, A.8
Vasta, A.9
Lembo, G.10
-
39
-
-
0343048978
-
Improvement of nitric oxide-dependent vasodilatation by HMG-CoA reductase inhibitors through attenuation of endothelial superoxide anion formation
-
Wagner AH, Köhler T, Rückschloss U, Just I, and Hecker M (2000) Improvement of nitric oxide-dependent vasodilatation by HMG-CoA reductase inhibitors through attenuation of endothelial superoxide anion formation. Arterioscler Thromb Vasc Biol 20:61-69. (Pubitemid 30048347)
-
(2000)
Arteriosclerosis, Thrombosis, and Vascular Biology
, vol.20
, Issue.1
, pp. 61-69
-
-
Wagner, A.H.1
Kohler, T.2
Ruckschloss, U.3
Just, I.4
Hecker, M.5
-
40
-
-
38049034068
-
Pleiotropic effects of statin therapy: Molecular mechanisms and clinical results
-
Wang CY, Liu PY, and Liao JK (2008) Pleiotropic effects of statin therapy: Molecular mechanisms and clinical results. Trends Mol Med 14:37-44.
-
(2008)
Trends Mol Med
, vol.14
, pp. 37-44
-
-
Wang, C.Y.1
Liu, P.Y.2
Liao, J.K.3
-
41
-
-
58149395046
-
Contribution of guanine nucleotide exchange factor Vav2 to hyperhomocysteinemic glomerulosclerosis in rats
-
Yi F, Xia M, Li N, Zhang C, Tang L, and Li PL (2009) Contribution of guanine nucleotide exchange factor Vav2 to hyperhomocysteinemic glomerulosclerosis in rats. Hypertension 53:90-96.
-
(2009)
Hypertension
, vol.53
, pp. 90-96
-
-
Yi, F.1
Xia, M.2
Li, N.3
Zhang, C.4
Tang, L.5
Li, P.L.6
-
42
-
-
34250315352
-
Acid sphingomyelinase and its redox amplification in formation of lipid raft redox signaling platforms in endothelial cells
-
Zhang AY, Yi F, Jin S, Xia M, Chen QZ, Gulbins E, and Li PL (2007) Acid sphingomyelinase and its redox amplification in formation of lipid raft redox signaling platforms in endothelial cells. Antioxid Redox Signal 9:817-828.
-
(2007)
Antioxid Redox Signal
, vol.9
, pp. 817-828
-
-
Zhang, A.Y.1
Yi, F.2
Jin, S.3
Xia, M.4
Chen, Q.Z.5
Gulbins, E.6
Li, P.L.7
-
43
-
-
31744443116
-
Lipid raft clustering and redox signaling platform formation in coronary arterial endothelial cells
-
DOI 10.1161/10.1161/01.HYP.0000196727.53300.62
-
Zhang AY, Yi F, Zhang G, Gulbins E, and Li PL (2006) Lipid raft clustering and redox signaling platform formation in coronary arterial endothelial cells. Hypertension 47:74-80. (Pubitemid 43177818)
-
(2006)
Hypertension
, vol.47
, Issue.1
, pp. 74-80
-
-
Zhang, A.Y.1
Yi, F.2
Zhang, G.3
Gulbins, E.4
Li, P.-L.5
-
45
-
-
27644447883
-
Oxidized LDL downregulates ATP-binding cassette transporter-1 in human vascular endothelial cells via inhibiting liver X receptor (LXR)
-
DOI 10.1016/j.cardiores.2005.07.003, PII S0008636305003688
-
Zhu Y, Liao H, Xie X, Yuan Y, Lee TS, Wang N, Wang X, Shyy JY, and Stemerman MB (2005) Oxidized LDL downregulates ATP-binding cassette transporter-1 in human vascular endothelial cells via inhibiting liver X receptor (LXR). Cardiovasc Res 68:425-432. (Pubitemid 41566562)
-
(2005)
Cardiovascular Research
, vol.68
, Issue.3
, pp. 425-432
-
-
Zhu, Y.1
Liao, H.2
Xie, X.3
Yuan, Y.4
Lee, T.-S.5
Wang, N.6
Wang, X.7
Shyy, J.Y.-J.8
Stemerman, M.B.9
|