An Experimental and Computational Evolution-Based Method to Study a Mode of Co-evolution of Overlapping Open Reading Frames in the AAV2 Viral Genome

PLoS ONE

Volumn 8, Issue 6, 2013, Pages

  Kawano, Yasuhiro ^a,b   Neeley, Shane ^a   Adachi, Kei ^a   Nakai, Hiroyuki ^a  

^a OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

^b TAKARA BIO INC   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ASSEMBLY ACTIVATING PROTEIN; CAPSID PROTEIN; HEPTAPEPTIDE; PROTEIN VP3; UNCLASSIFIED DRUG; VIRUS PROTEIN;

ADENO ASSOCIATED VIRUS; AMINO ACID SEQUENCE; AMINO TERMINAL SEQUENCE; ARTICLE; CARBOXY TERMINAL SEQUENCE; COEVOLUTION; CONTROLLED STUDY; EMBRYO; GENETIC CONSERVATION; GENETIC VARIABILITY; HUMAN; HUMAN CELL; MOLECULAR EVOLUTION; NONHUMAN; NUCLEOTIDE SEQUENCE; OPEN READING FRAME; OVERLAPPING OPEN READING FRAME; PROTEIN MOTIF; SEQUENCE ANALYSIS; VIRUS GENOME; VIRUS INFECTIVITY; VIRUS PARTICLE;

AMINO ACID MOTIFS; AMINO ACID SEQUENCE; DEPENDOVIRUS; EVOLUTION, MOLECULAR; GENOME, VIRAL; HEK293 CELLS; HUMANS; MOLECULAR SEQUENCE DATA; MUTATION; OPEN READING FRAMES; SEQUENCE HOMOLOGY, AMINO ACID;

ADENO-ASSOCIATED VIRUS; MIRIDAE;

EID: 84879486500     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0066211     Document Type: Article

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