Coexpression of factor VIII heavy and light chain adeno-associated viral vectors produces biologically active protein

Proceedings of the National Academy of Sciences of the United States of America

Volumn 96, Issue 22, 1999, Pages 12725-12730

  Burton, Melissa ^a   Nakai, Hiroyuki ^a,b   Colosi, Peter ^a   Cunningham, Janet ^a   Mitchell, Rachel ^a   Couto, Linda ^a  

^a Avigen Inc   (United States)

^b STANFORD UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BLOOD CLOTTING FACTOR 8; CELL DNA; COMPLEMENTARY DNA; ELONGATION FACTOR 1ALPHA; PROTEIN SUBUNIT; RECOMBINANT PROTEIN;

ADENO ASSOCIATED VIRUS; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL TRANSFER; CONTROLLED STUDY; DNA DETERMINATION; DOSE TIME EFFECT RELATION; EXPRESSION VECTOR; HEMOPHILIA A; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN BLOOD LEVEL; PROTEIN DETERMINATION; PROTEIN EXPRESSION; TREATMENT OUTCOME;

ANIMALS; CELL LINE; DEPENDOVIRUS; FACTOR VIII; GENE TRANSFER TECHNIQUES; GENETIC VECTORS; HUMANS; LIVER; MICE; MICE, INBRED C57BL; RECOMBINANT PROTEINS; RECOMBINATION, GENETIC;

ADENO-ASSOCIATED VIRUS; ANIMALIA;

EID: 0033607305     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.96.22.12725     Document Type: Article

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