Sox2 suppresses the invasiveness of breast cancer cells via a mechanism that is dependent on Twist1 and the status of Sox2 transcription activity

BMC Cancer

Volumn 13, Issue , 2013, Pages

  Wu, Fang ^a   Ye, Xiaoxia ^a   Wang, Peng ^a   Jung, Karen ^a   Wu, Chengsheng ^a   Douglas, Donna ^a   Kneteman, Norman ^a   Bigras, Gilbert ^a   Ma, Yupo ^b   Lai, Raymond ^a,c  

^a UNIVERSITY OF ALBERTA   (Canada)

^b STONY BROOK UNIVERSITY   (United States)

^c DynaLIFE Dx   (Canada)

Author keywords

Breast cancer; Invasiveness; Sox2; Transcription activity; Twist1

Indexed keywords

SMALL INTERFERING RNA; TRANSCRIPTION FACTOR SOX2; NUCLEAR PROTEIN; SOX2 PROTEIN, HUMAN; TRANSCRIPTION FACTOR SOX; TRANSCRIPTION FACTOR TWIST; TWIST1 PROTEIN, HUMAN;

ARTICLE; BREAST CANCER; CANCER CELL; CHROMATIN IMMUNOPRECIPITATION; EPITHELIAL MESENCHYMAL TRANSITION; HUMAN; HUMAN CELL; IN VITRO STUDY; PROMOTER REGION; PROTEIN BINDING; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WESTERN BLOTTING; BREAST TUMOR; FEMALE; GENE EXPRESSION REGULATION; GENE SILENCING; GENETIC TRANSCRIPTION; GENETICS; METABOLISM; PATHOLOGY; PHYSIOLOGY; SIGNAL TRANSDUCTION; TRANSCRIPTION INITIATION; TUMOR CELL LINE; TUMOR INVASION;

BLOTTING, WESTERN; BREAST NEOPLASMS; CELL LINE, TUMOR; CHROMATIN IMMUNOPRECIPITATION; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; GENE KNOCKDOWN TECHNIQUES; HUMANS; NEOPLASM INVASIVENESS; NUCLEAR PROTEINS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; SOXB1 TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC; TRANSCRIPTIONAL ACTIVATION; TWIST TRANSCRIPTION FACTOR;

EID: 84879479051     PISSN: None     EISSN: 14712407     Source Type: Journal    
DOI: 10.1186/1471-2407-13-317     Document Type: Article

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