Indexed keywords
ANTIINFLAMMATORY AGENT;
TETRAHYDRO PYRAZOLO [4,3 C] PYRIDINE DERIVATIVE;
TUMOR NECROSIS FACTOR ALPHA;
UNCLASSIFIED DRUG;
3 TERT BUTYL 5 ETHYL 3 METHYL 4,5,6,7 TETRAHYDRO 1H PYRAZOLO[4,3 C]PYRIDINE 1 CARBOXAMIDE;
3 TERT BUTYL N (2,4 DIMETHYLPHENYL) 5 ETHYL 3 METHYL 4,5,6,7 TETRAHYDRO 1H PYRAZOLO[4,3 C]PYRIDINE 1 CARBOXAMIDE;
3 TERT BUTYL N (2,5 DIMETHYLPHENYL) 5 ETHYL 3 METHYL 4,5,6,7 TETRAHYDRO 1H PYRAZOLO[4,3 C]PYRIDINE 1 CARBOXAMIDE;
3 TERT BUTYL N (2,6 DIMETHYLPHENYL) 5 ETHYL 3 METHYL 4,5,6,7 TETRAHYDRO 1H PYRAZOLO[4,3 C]PYRIDINE 1 CARBOXAMIDE;
3 TERT BUTYL N (4 CHLOROPHENYL) 5 ETHYL 4,5,6,7 TETRAHYDRO 1H PYRAZOLO[4,3 C]PYRIDINE 1 CARBOXAMIDE;
3 TERT BUTYL N 5 ETHYL N (2 FLUORO5 METHYLPHENYL) 4,5,6,7 TETRAHYDRO 1H PYRAZOLO[4,3 C]PYRIDINE 1 CARBOXAMIDE;
3 TERT BUTYL N 5 ETHYL N [3 (TRIFLUOROMETHYL)PHENYL] 4,5,6,7 TETRAHYDRO 1H PYRAZOLO[4,3 C]PYRIDINE 1 CARBOXAMIDE;
5 ETHYL 3 METHYL N [3 (TRIFLUORO)PHENYL] 4,5,6,7 TETRAHYDRO 1H PYRAZOLO[4,3 C]PYRIDINE 1 CARBOXAMIDE;
5 ETHYL N (2 FLUORO 5 METHYLPHENYL) 5 ETHYL 3 METHYL 4,5,6,7 TETRAHYDRO 1H PYRAZOLO[4,3 C]PYRIDINE 1 CARBOXAMIDE;
CANNABINOID 1 RECEPTOR;
GABAPENTIN;
INDOMETACIN;
N (2,4 DIFLUOROPHENYL) 5 ETHYL 3 METHYL 4,5,6,7 TETRAHYDRO 1H PYRAZOLO[4,3 C]PYRIDINE 1 CARBOXAMIDE;
N (2,4 DIMETHYLPHENYL) 5 ETHYL 3 METHYL 4,5,6,7 TETRAHYDRO 1H PYRAZOLO[4,3 C]PYRIDINE 1 CARBOXAMIDE;
N (2,5 DIMETHYLPHENYL) 5 ETHYL 3 METHYL 4,5,6,7 TETRAHYDRO 1H PYRAZOLO[4,3 C]PYRIDINE 1 CARBOXAMIDE;
N (2,6 DIMETHYLPHENYL) 5 ETHYL 3 METHYL 4,5,6,7 TETRAHYDRO 1H PYRAZOLO[4,3 C]PYRIDINE 1 CARBOXAMIDE;
N (4 BROMOPHENYL) 5 ETHYL 3 METHYL 4,5,6,7 TETRAHYDRO 1H PYRAZOLO[4,3 C]PYRIDINE 1 CARBOXAMIDE;
N (4 CHLOROPHENYL) 5 ETHYL 3 METHYL 4,5,6,7 TETRAHYDRO 1H PYRAZOLO[4,3 C]PYRIDINE 1 CARBOXAMIDE;
NITRIC OXIDE;
PYRAZOLE DERIVATIVE;
ANIMAL EXPERIMENT;
ANIMAL MODEL;
ANTIINFLAMMATORY ACTIVITY;
ARTICLE;
CONTROLLED STUDY;
DRUG SYNTHESIS;
MOUSE;
NEUROPATHIC PAIN;
NONHUMAN;
SCIATIC NERVE INJURY;
ALLODYNIA;
ANALGESIC ACTIVITY;
CHRONIC CONSTRICTION INJURY;
DRUG EFFICACY;
DRUG SYNOVIAL FLUID LEVEL;
FEMALE;
HYPERALGESIA;
MALE;
NEUROTOXICITY;
PAIN;
PHARMACOPHORE;
1
0002084907
Issues in the management of neuropathic pain
A.I. Bausbaum, J.-M. Besson (Eds.), Wiley, New York
R.K. Portenoy, Issues in the management of neuropathic pain, in: A.I. Bausbaum, J.-M. Besson (Eds.), Towards a New Pharmacology of Pain, Wiley, New York, 1991, pp. 393-416.
(1991)
Towards a New Pharmacology of Pain
, pp. 393-416
Portenoy, R.K.1
8
0035840826
V. Morisset, J. Ahluwalia, I. Nagy, L. Urban, Eur. J. Pharmacol. 429 (2001) 93-100.
(2001)
Eur. J. Pharmacol.
, vol.429
, pp. 93-100
Morisset, V.1
Ahluwalia, J.2
Nagy, I.3
Urban, L.4
10
84884291034
US Patent 2007, 0254911A1
M. Xia, M. Pan, F. Liotta, M.P. Wachter, US Patent 2007, 0254911A1.
Xia, M.1
Pan, M.2
Liotta, F.3
Wachter, M.P.4
11
9144263557
R.L. Thurmond, S. Sun, C.A. Sehon, S.M. Baker, H. Cai, Y. Gu, W. Jiang, J.P. Riley, K.N. Williams, J.P. Edwards, L. Karlsson, J. Pharmacol. Exp. Ther. 308 (2004) 268-276.
(2004)
J. Pharmacol. Exp. Ther.
, vol.308
, pp. 268-276
Thurmond, R.L.1
Sun, S.2
Sehon, C.A.3
Baker, S.M.4
Cai, H.5
Gu, Y.6
Jiang, W.7
Riley, J.P.8
Williams, K.N.9
Edwards, J.P.10
Karlsson, L.11
12
20044390727
D.J. Gustin, C.A. Sehon, J. Wei, H. Cai, S.P. Meduna, H. Khatuya, S. Sun, Y. Gu, W. Jiang, R.L. Thurmond, L. Karlsson, J.P. Edwards, Bioorg. Med. Chem. Lett. 15 (2005) 1687-1691.
(2005)
Bioorg. Med. Chem. Lett.
, vol.15
, pp. 1687-1691
Gustin, D.J.1
Sehon, C.A.2
Wei, J.3
Cai, H.4
Meduna, S.P.5
Khatuya, H.6
Sun, S.7
Gu, Y.8
Jiang, W.9
Thurmond, R.L.10
Karlsson, L.11
Edwards, J.P.12
13
33644815279
C.A. Grice, G. Tays, H. Khatuya, D.J. Gustin, C.R. Butler, J. Wei, C.A. Sehon, S. Sun, Y. Gu, W. Jiang, R.L. Thurmond, L. Karlsson, J.P. Edwards, Bioorg. Med. Chem. Lett. 16 (2006) 2209-2212.
(2006)
Bioorg. Med. Chem. Lett.
, vol.16
, pp. 2209-2212
Grice, C.A.1
Tays, G.2
Khatuya, H.3
Gustin, D.J.4
Butler, C.R.5
Wei, J.6
Sehon, C.A.7
Sun, S.8
Gu, Y.9
Jiang, W.10
Thurmond, R.L.11
Karlsson, L.12
Edwards, J.P.13
14
34548580127
J. Wei, B.A. Pio, H. Cai, S.P. Meduna, S. Sun, Y. Gu, W. Jiang, R.L. Thurmond, L. Karlson, J.P. Edwards, Bioorg. Med. Chem. Lett. 17 (2007) 5525-5529.
(2007)
Bioorg. Med. Chem. Lett.
, vol.17
, pp. 5525-5529
Wei, J.1
Pio, B.A.2
Cai, H.3
Meduna, S.P.4
Sun, S.5
Gu, Y.6
Jiang, W.7
Thurmond, R.L.8
Karlson, L.9
Edwards, J.P.10
15
71749093965
M.K. Ameriks, F.U. Axe, D. Bembenek, J.P. Edward, Y. Gu, L. Karlon, M. Randel, S. Sun, R.L. Thurmond, J. Zhu, Bioorg. Med. Chem. Lett. 19 (2009) 6131-6134.
(2009)
Bioorg. Med. Chem. Lett.
, vol.19
, pp. 6131-6134
Ameriks, M.K.1
Axe, F.U.2
Bembenek, D.3
Edward, J.P.4
Gu, Y.5
Karlon, L.6
Randel, M.7
Sun, S.8
Thurmond, R.L.9
Zhu, J.10
16
33846404143
R. Soliva, J.L. Gelpi, C. Almansa, M. Virgili, M. Orozco, J. Med. Chem. 50 (2007) 283-293.
(2007)
J. Med. Chem.
, vol.50
, pp. 283-293
Soliva, R.1
Gelpi, J.L.2
Almansa, C.3
Virgili, M.4
Orozco, M.5
17
76649090599
T. Sifferlen, C. Bos, E. Cottreel, R. Koberstein, M. Gude, H. Aissaoui, T. Weller, J. Gatfield, C. Brisbare-Roch, F. Jenck, Bioorg. Med. Chem. Lett. 20 (2010) 1539-1542.
(2010)
Bioorg. Med. Chem. Lett.
, vol.20
, pp. 1539-1542
Sifferlen, T.1
Bos, C.2
Cottreel, E.3
Koberstein, R.4
Gude, M.5
Aissaoui, H.6
Weller, T.7
Gatfield, J.8
Brisbare-Roch, C.9
Jenck, F.10
19
3242741033
P. Yogeeswari, D. Sriram, S.N. Pandeya, J.P. Stables, Farmaco 59 (2004) 609-613.
(2004)
Farmaco
, vol.59
, pp. 609-613
Yogeeswari, P.1
Sriram, D.2
Pandeya, S.N.3
Stables, J.P.4
20
3242746776
P. Yogeeswari, R. Thirumurugan, R. Kavya, J.S. Samuel, J.P. Stables, D. Sriram, Eur. J. Med. Chem. 39 (2004) 729-734.
(2004)
Eur. J. Med. Chem.
, vol.39
, pp. 729-734
Yogeeswari, P.1
Thirumurugan, R.2
Kavya, R.3
Samuel, J.S.4
Stables, J.P.5
Sriram, D.6
21
14644438358
P. Yogeeswari, D. Sriram, V. Veena, R. Kavya, K. Rakhra, S. Mehta, J.V. Ragavendran, R. Thirumurugan, J.P. Stables, Biomed. Pharmacother. 59 (2005) 51-55.
(2005)
Biomed. Pharmacother.
, vol.59
, pp. 51-55
Yogeeswari, P.1
Sriram, D.2
Veena, V.3
Kavya, R.4
Rakhra, K.5
Mehta, S.6
Ragavendran, J.V.7
Thirumurugan, R.8
Stables, J.P.9
22
0028803880
H. McQuay, D. Caroll, A.R. Jadad, P. Wiffen, A. Moore, Br. Med. J. 311 (1995) 1047-1052.
(1995)
Br. Med. J.
, vol.311
, pp. 1047-1052
McQuay, H.1
Caroll, D.2
Jadad, A.R.3
Wiffen, P.4
Moore, A.5
23
34249082410
P. Yogeeswari, J.V. Ragavendran, D. Sriram, Y. Nageswari, R. Kavya, N. Sreevatsan, K. Vanitha, J. Stables, J. Med. Chem. 50 (2007) 2459-2467.
(2007)
J. Med. Chem.
, vol.50
, pp. 2459-2467
Yogeeswari, P.1
Ragavendran, J.V.2
Sriram, D.3
Nageswari, Y.4
Kavya, R.5
Sreevatsan, N.6
Vanitha, K.7
Stables, J.8
24
36248992805
P. Yogeeswari, J.V. Ragavendran, D. Sriram, R. Kavya, R. Vanitha, H. Neelakantan, Pharmacology 81 (2008) 21-31.
(2008)
Pharmacology
, vol.81
, pp. 21-31
Yogeeswari, P.1
Ragavendran, J.V.2
Sriram, D.3
Kavya, R.4
Vanitha, R.5
Neelakantan, H.6
25
77953208857
P. Yogeeswari, J.V. Ragavendran, D. Sriram, A. Priyanka, S. Ganguly, A.S.K. Reddy, A. Semwal, Pharmacol. Online 1 (2010) 575-590.
(2010)
Pharmacol. Online
, vol.1
, pp. 575-590
Yogeeswari, P.1
Ragavendran, J.V.2
Sriram, D.3
Priyanka, A.4
Ganguly, S.5
Reddy, A.S.K.6
Semwal, A.7
26
77957267999
P. Yogeeswari, A. Semwal, D. Sriram, J.V. Ragavendran, N. Sreevatsan, M. Sharma, Pharmacol. Online 1 (2010) 634-647.
(2010)
Pharmacol. Online
, vol.1
, pp. 634-647
Yogeeswari, P.1
Semwal, A.2
Sriram, D.3
Ragavendran, J.V.4
Sreevatsan, N.5
Sharma, M.6
27
0347380971
P. Yogeeswari, D. Sriram, A. Brahmandam, I. Sridharan, R. Thirumurugan, J.P. Stables, Med. Chem. Res. 12 (2003) 57-68.
(2003)
Med. Chem. Res.
, vol.12
, pp. 57-68
Yogeeswari, P.1
Sriram, D.2
Brahmandam, A.3
Sridharan, I.4
Thirumurugan, R.5
Stables, J.P.6
28
26444438132
P. Yogeeswari, D. Sriram, R. Thirumurugan, J.V. Raghavendran, K. Sudhan, R. Kumar, J. Stables, J. Med. Chem. 48 (2005) 6202-6211.
(2005)
J. Med. Chem.
, vol.48
, pp. 6202-6211
Yogeeswari, P.1
Sriram, D.2
Thirumurugan, R.3
Raghavendran, J.V.4
Sudhan, K.5
Kumar, R.6
Stables, J.7
29
84861988708
A. Semwal, P. Yogeeswari, J.V. Ragavendran, D. Sriram, J. Stables, Int. J. Drug Des. Discov. 1 (2010) 169-187.
(2010)
Int. J. Drug Des. Discov.
, vol.1
, pp. 169-187
Semwal, A.1
Yogeeswari, P.2
Ragavendran, J.V.3
Sriram, D.4
Stables, J.5
30
79957496154
P. Yogeeswari, N. Menon, A. Semwal, M. Arjun, D. Sriram, Eur. J. Med. Chem. 46 (2011) 2964-2970.
(2011)
Eur. J. Med. Chem.
, vol.46
, pp. 2964-2970
Yogeeswari, P.1
Menon, N.2
Semwal, A.3
Arjun, M.4
Sriram, D.5
31
84868130114
M. Sharma, S. Garigipati, B. Kundu, D. Vanamala, A. Semwal, D. Sriram, P. Yogeeswari, Chem. Biol. Drug Des. 8 (2012) 961-970.
(2012)
Chem. Biol. Drug Des.
, vol.8
, pp. 961-970
Sharma, M.1
Garigipati, S.2
Kundu, B.3
Vanamala, D.4
Semwal, A.5
Sriram, D.6
Yogeeswari, P.7
32
84928474769
M. Sharma, D. Vanamala, A. Semwal, D. Sriram, P. Yogeeswari, Pain Ther. 1 (2012) 1-17.
(2012)
Pain Ther.
, vol.1
, pp. 1-17
Sharma, M.1
Vanamala, D.2
Semwal, A.3
Sriram, D.4
Yogeeswari, P.5
33
84870263235
M. Sharma, S.S. Dash, G. Matharasala, V. Deekshith, D. Sriram, P. Yogeeswari, Antiinflamm. Antiallerg. Agents Med. Chem. 11 (2012) 182-190.
(2012)
Antiinflamm. Antiallerg. Agents Med. Chem.
, vol.11
, pp. 182-190
Sharma, M.1
Dash, S.S.2
Matharasala, G.3
Deekshith, V.4
Sriram, D.5
Yogeeswari, P.6
34
33748855540
P. Yogeeswari, D. Sriram, R. Thirumurugan, L.R. Jeevanlal, S. Jit, J.V. Ragavendran, R. Kavya, K. Rakhra, V. Saraswat, Acta Pharm. 56 (2006) 259-272.
(2006)
Acta Pharm.
, vol.56
, pp. 259-272
Yogeeswari, P.1
Sriram, D.2
Thirumurugan, R.3
Jeevanlal, L.R.4
Jit, S.5
Ragavendran, J.V.6
Kavya, R.7
Rakhra, K.8
Saraswat, V.9
35
33750993503
M. Shalini, P. Yogeeswari, D. Sriram, P. Kudyar, P.R. Kumar, S. Induja, J.P. Stables, Med. Chem. 2 (2006) 617-625.
(2006)
Med. Chem.
, vol.2
, pp. 617-625
Shalini, M.1
Yogeeswari, P.2
Sriram, D.3
Kudyar, P.4
Kumar, P.R.5
Induja, S.6
Stables, J.P.7
36
34250176233
P. Yogeeswari, D. Sriram, P. Sahithya, J.V. Ragavendran, V. Ranganadh, Bioorg. Med. Chem. Lett. 17 (2007) 3712-3715.
(2007)
Bioorg. Med. Chem. Lett.
, vol.17
, pp. 3712-3715
Yogeeswari, P.1
Sriram, D.2
Sahithya, P.3
Ragavendran, J.V.4
Ranganadh, V.5
38
4544321692
R.L. Thurmond, M.P. Beavers, H. Cai, S.P. Meduna, D.J. Gustin, S. Sun, H.J. Almond, L. Karlsson, J.P. Edwards, J. Med. Chem. 47 (2004) 4799-4801.
(2004)
J. Med. Chem.
, vol.47
, pp. 4799-4801
Thurmond, R.L.1
Beavers, M.P.2
Cai, H.3
Meduna, S.P.4
Gustin, D.J.5
Sun, S.6
Almond, H.J.7
Karlsson, L.8
Edwards, J.P.9
40
84884282266
US Patent 2004, 0014801A1
F.E. Cohen, X. Du, C. Guo, J.H. McKerrow, US Patent 2004, 0014801A1.
Cohen, F.E.1
Du, X.2
Guo, C.3
McKerrow, J.H.4
46
1242273764
T. Garth, J.H. Whiteside, B. Jamie, M. Lilly, P. Michelle, G. Susan, W. Katharine, Br. J. Pharmacol. 141 (2004) 85-91.
(2004)
Br. J. Pharmacol.
, vol.141
, pp. 85-91
Garth, T.1
Whiteside, J.H.2
Jamie, B.3
Lilly, M.4
Michelle, P.5
Susan, G.6
Katharine, W.7
47
0028558684
Y. Choi, Y.W. Yoon, H.S. Na, S.H. Kim, J.M. Chung, Pain 59 (1994) 369-376.
(1994)
Pain
, vol.59
, pp. 369-376
Choi, Y.1
Yoon, Y.W.2
Na, H.S.3
Kim, S.H.4
Chung, J.M.5
48
0032860773
E. Eliav, U. Herzberg, M.A. Ruda, G.J. Bennett, Pain 83 (1999) 169-182.
(1999)
Pain
, vol.83
, pp. 169-182
Eliav, E.1
Herzberg, U.2
Ruda, M.A.3
Bennett, G.J.4
49
0035073284
R.M.Caudle, A.J.Mannes, R.Benoliel, E. Eliav,M.J. Iadarola, J. Pain2 (2001)118-127.
(2001)
J. Pain
, vol.2
, pp. 118-127
Caudle, R.M.1
Mannes, A.J.2
Benoliel, R.3
Eliav, E.4
Iadarola, M.J.5
51
0033812468
C.A. Fairbanks, H.O. Nguyen, B.M. Grocholski, G.L. Wilcox, Anesthesiology 93 (2000) 765-773.
(2000)
Anesthesiology
, vol.93
, pp. 765-773
Fairbanks, C.A.1
Nguyen, H.O.2
Grocholski, B.M.3
Wilcox, G.L.4
56
1342343936
J.D. Leggett, S. Aspley, S.R. Beckett, A.M. D'Antona, D.A. Kendall, Br. J. Pharmacol. 141 (2004) 253-262.
(2004)
Br. J. Pharmacol.
, vol.141
, pp. 253-262
Leggett, J.D.1
Aspley, S.2
Beckett, S.R.3
D'Antona, A.M.4
Kendall, D.A.5
58
0037087364
C.S. Hsieh, P. deRoos, K. Honey, C. Beers, A.Y. Rudensky, S. Aspley, J. Immunol. 168 (2002) 2618-2625.
(2002)
J. Immunol.
, vol.168
, pp. 2618-2625
Hsieh, C.S.1
DeRoos, P.2
Honey, K.3
Beers, C.4
Rudensky, A.Y.5
Aspley, S.6