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Volumn 80, Issue 6, 2012, Pages 961-970

Discovery of Novel 1,2,4-Triazol-5-Ones as Tumor Necrosis Factor-Alpha Inhibitors for the Treatment of Neuropathic Pain

Author keywords

1,2,4 triazol 5 one; Antiallodynic; Antihyperalgesic; Carrageenan induced paw edema; Neuropathic pain; Nitric oxide; Tumor necrosis factor alpha

Indexed keywords

1,2,4 TRIAZOL 5 ONE DERIVATIVE; 3 (4 PHENOXYPHENYL) 4 [3 (TRIFLUOROMETHYL)PHENYL] 1H 1,2,4 TRIAZOL 5(4H) ONE; 3 (5 NITROFURAN 2 YL) 4 [3 (TRIFLUOROMETHYL)PHENYL] 1H 1,2,4 TRIAZOL 5(4H) ONE; 3 (HEPTAN 4 YL) 4 [3 (TRIFLUOROMETHYL)PHENYL] 1H 1,2,4 TRIAZOL 5(4H) ONE; 4 (2,4 DIMETHYLPHENYL) 3 (5 NITROFURAN 2 YL) 1H 1,2,4 TRIAZOL 5(4H) ONE; 4 (2,4 DIMETHYLPHENYL) 3 (HEPTAN 4 YL) 1H 1,2,4 TRIAZOL 5(4H) ONE; 4 (2,4 DIMETHYLPHENYL) 3 (PYRAZIN 2 YL) 1H 1,2,4 TRIAZOL 5(4H) ONE; 4 (2,5 DIMETHYLPHENYL) 3 (4 PHENOXYPHENYL) 1H 1,2,4 TRIAZOL 5(4H) ONE; 4 (2,5 DIMETHYLPHENYL) 3 (5 NITROFURAN 2 YL) 1H 1,2,4 TRIAZOL 5(4H) ONE; 4 (2,5 DIMETHYLPHENYL) 3 (HEPTAN 4 YL) 1H 1,2,4 TRIAZOL 5(4H) ONE; 4 (2,5 DIMETHYLPHENYL) 3 (PYRAZIN 2 YL) 1H 1,2,4 TRIAZOL 5(4H) ONE; 4 (2,6 DIMETHYLPHENYL) 3 (4 PHENOXYPHENYL) 1H 1,2,4 TRIAZOL 5(4H) ONE; 4 (2,6 DIMETHYLPHENYL) 3 (5 NITROFURAN 2 YL) 1H 1,2,4 TRIAZOL 5(4H) ONE; 4 (2,6 DIMETHYLPHENYL) 3 (HEPTAN 4 YL) 1H 1,2,4 TRIAZOL 5(4H) ONE; 4 (2,6 DIMETHYLPHENYL) 3 (PYRAZIN 2 YL) 1H 1,2,4 TRIAZOL 5(4H) ONE; 4 (4 BROMOPHENYL) 3 (4 PHENOXYPHENYL) 1H 1,2,4 TRIAZOL 5(4H) ONE; 4 (4 BROMOPHENYL) 3 (5 NITROFURAN 2 YL) 1H 1,2,4 TRIAZOL 5(4H) ONE; 4 (4 BROMOPHENYL) 3 (HEPTAN 4 YL) 1H 1,2,4 TRIAZOL 5(4H) ONE; 4 (4 BROMOPHENYL) 3 (PYRAZIN 2 YL) 1H 1,2,4 TRIAZOL 5(4H) ONE; 4 (4 CHLOROPHENYL) 3 (4 PHENOXYPHENYL) 1H 1,2,4 TRIAZOL 5(4H) ONE; 4 (4 CHLOROPHENYL) 3 (5 NITROFURAN 2 YL) 1H 1,2,4 TRIAZOL 5(4H) ONE; 4 (4 CHLOROPHENYL) 3 (HEPTAN 4 YL) 1H 1,2,4 TRIAZOL 5(4H) ONE; 4 (4 CHLOROPHENYL) 3 (PYRAZIN 2 YL) 1H 1,2,4 TRIAZOL 5(4H) ONE; TUMOR NECROSIS FACTOR ALPHA INHIBITOR; UNCLASSIFIED DRUG;

EID: 84868130114     PISSN: 17470277     EISSN: 17470285     Source Type: Journal    
DOI: 10.1111/cbdd.12049     Document Type: Article
Times cited : (10)

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