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Volumn 2, Issue , 2010, Pages 634-647

Antiallodynic and antihyperalgesic activities of anticonvulsant gaba derivatives in both sciatic nerve and spinal nerve ligation models of neuropathic pain

Author keywords

aminobutyric acid; Analgesic activity; Antiallodynic; Antihyperalgesic; Gaba; Neuropathic pain; Thiosemicarbazones

Indexed keywords

4 (1,3 DIOXO 1,3 DIHYDRO 2H ISOINDOL 2 YL) N (4 METHYLPHENYL)BUTANAMIDE; 4 (2 CYCLOHEXYLIDENE HYDRAZINE CARBOTHIOAMIDO)BUTANOIC ACID; 4 (2 CYCLOPENTYLIDENE HYDRAZINE CARBOTHIOAMIDO)BUTANOIC ACID; 4 (HYDRAZINE CARBOTHIOAMIDO)BUTANOIC ACID; 4 [2 (1 PHENYLETHYLIDENE)HYDRAZINE CARBOTHIOAMIDO]BUTANOIC ACID; 4 [2 (1,3 DIPHENYLPROPAN 2 YLIDENE)HYDRAZINE CARBOTHIOAMIDO]BUTANOIC ACID; 4 [2 (2 HYDROXYBENZYLIDENE)HYDRAZINE CARBOTHIOAMIDO]BUTANOIC ACID; 4 [2 (2 OXOINDOLIN 3 YLIDENE)HYDRAZINE CARBOTHIOAMIDO]BUTANOIC ACID; 4 [2 (3 NITROBENZYLIDENE)HYDRAZINE CARBOTHIOAMIDO]BUTANOIC ACID; 4 [2 (4 CHLOROBENZYLIDENE)HYDRAZINE CARBOTHIOAMIDO]BUTANOIC ACID; 4 [2 (4 NITROBENZYLIDENE)HYDRAZINE CARBOTHIOAMIDO]BUTANOIC ACID; 4 [2 (DIPHENYLMETHYLENE)HYDRAZINECARBOTHIOAMIDO]BUTANOIC ACID; 4 [2 [1 (3 AMINOPHENYL)ETHYLIDENE]HYDRAZINECARBOTHIOAMIDO]BUTANOIC ACID; 4 [2 [1 (4 NITROPHENYL)ETHYLIDENE]HYDRAZINECARBOTHIOAMIDO]BUTANOIC ACID; 4 [2 [4 (DIMETHYLAMINO)BENZYLIDENE]HYDRAZINE CARBOTHIOAMIDO]BUTANOIC ACID; 4 [2 [4 BROMOPHENYL (PHENYL)METHYLENE]HYDRAZINE CARBOTHIOAMIDO]BUTANOIC ACID; 4 AMINOBUTYRIC ACID DERIVATIVE; ACETIC ACID; ACETYLSALICYLIC ACID; ANALGESIC AGENT; CARBAMAZEPINE; GABAPENTIN; LAMOTRIGINE; PENTOBARBITAL; UNCLASSIFIED DRUG;

EID: 77957267999     PISSN: None     EISSN: 18278620     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (1)

References (25)
  • 3
    • 0036366760 scopus 로고    scopus 로고
    • Anticonvulsants in neuropathic pain: Rationale and clinical evidence
    • Jensen, TS. Anticonvulsants in neuropathic pain: rationale and clinical evidence. Eur J Pain 2002; 6: 61-68.
    • (2002) Eur J Pain , vol.6 , pp. 61-68
    • Jensen, T.S.1
  • 4
    • 2942754158 scopus 로고    scopus 로고
    • GABA(B) receptor agonist baclofen has non-specific antinociceptive effect in the model of peripheral neuropathy in the rat
    • Franek, M, Vaculin, S, Rokyta, R. GABA(B) receptor agonist baclofen has non-specific antinociceptive effect in the model of peripheral neuropathy in the rat. Physiol Res 2004; 53: 351-355.
    • (2004) Physiol Res , vol.53 , pp. 351-355
    • Franek, M.1    Vaculin, S.2    Rokyta, R.3
  • 5
    • 0027982034 scopus 로고
    • Increased sensitivity to the antinociceptive activity of (+/-)-baclofen in an animal model of chronic neuropathic, but not chronic inflammatory hyperalgesia
    • Smith GD, Harrison SM, Birch PJ et al. Increased sensitivity to the antinociceptive activity of (+/-)-baclofen in an animal model of chronic neuropathic, but not chronic inflammatory hyperalgesia. Neuropharmacol 1994; 33: 1103-1108.
    • (1994) Neuropharmacol , vol.33 , pp. 1103-1108
    • Smith, G.D.1    Harrison, S.M.2    Birch, P.J.3
  • 6
    • 0030966704 scopus 로고    scopus 로고
    • The effect of spinal GABA receptor agonists on tactile allodynia in a surgically-induced neuropathic pain model in the rat
    • Hwang JH, Yaksh TL. The effect of spinal GABA receptor agonists on tactile allodynia in a surgically-induced neuropathic pain model in the rat. Pain 1997; 70: 15-22.
    • (1997) Pain , vol.70 , pp. 15-22
    • Hwang, J.H.1    Yaksh, T.L.2
  • 7
    • 0032734824 scopus 로고    scopus 로고
    • Possible analgesic effect of vigabatrin in animal experimental chronic neuropathic pain
    • Alves ND, De Castro CCM, De Carvalho AM, et al. Possible analgesic effect of vigabatrin in animal experimental chronic neuropathic pain. Arq. Neuropsiquiatr 1999; 57: 916-920.
    • (1999) Arq. Neuropsiquiatr , vol.57 , pp. 916-920
    • Alves, N.D.1    de Castro, C.C.M.2    de Carvalho, A.M.3
  • 8
    • 33847140707 scopus 로고    scopus 로고
    • Design and synthesis of anticonvulsants from a combined phthalimide-GABA-anilide and hydrazone pharmacophore
    • Ragavendran JV, Sriram D, Patel SK, et al. Design and synthesis of anticonvulsants from a combined phthalimide-GABA-anilide and hydrazone pharmacophore. Eur J Med Chem 2007;42: 146-151.
    • (2007) Eur J Med Chem , vol.42 , pp. 146-151
    • Ragavendran, J.V.1    Sriram, D.2    Patel, S.K.3
  • 9
    • 34249082410 scopus 로고    scopus 로고
    • Discovery of 4-aminobutyric acid derivatives possessing anticonvulsant and antinociceptive activities: A hybrid pharmacophore approach
    • Yogeeswari P, Ragavendran JV, Sriram D, et al. Discovery of 4-aminobutyric acid derivatives possessing anticonvulsant and antinociceptive activities: a hybrid pharmacophore approach. J Med Chem 2007; 50: 2459-2467.
    • (2007) J Med Chem , vol.50 , pp. 2459-2467
    • Yogeeswari, P.1    Ragavendran, J.V.2    Sriram, D.3
  • 10
    • 0035178865 scopus 로고    scopus 로고
    • Anticonvulsant and neurotoxicity evaluation of 5-(un)-substituted isatinimino derivatives
    • Pandeya SN, Sriram D, Yogeeswari P, et al. Anticonvulsant and neurotoxicity evaluation of 5-(un)-substituted isatinimino derivatives. Pharmazie 2001;56: 875-876.
    • (2001) Pharmazie , vol.56 , pp. 875-876
    • Pandeya, S.N.1    Sriram, D.2    Yogeeswari, P.3
  • 11
    • 0036501108 scopus 로고    scopus 로고
    • Anticonvulsant and neurotoxicity evaluation of some 6-chlorobenzothiazolyl-2-thiosemicarbazones
    • Yogeeswari P, Sriram D, Suniljit LRJ, Kumar et al. Anticonvulsant and neurotoxicity evaluation of some 6-chlorobenzothiazolyl-2-thiosemicarbazones. Eur J Med Chem 2002; 37: 231-236.
    • (2002) Eur J Med Chem , vol.37 , pp. 231-236
    • Yogeeswari, P.1    Sriram, D.2    Suniljit, L.R.J.3    Kumar4
  • 12
    • 0242270809 scopus 로고    scopus 로고
    • Synthesis and anticonvulsant and neurotoxicity evaluation of N4-phthalimido phenyl (thio) semicarbazides
    • Yogeeswari P, Sriram D, Saraswat V, et al. Synthesis and anticonvulsant and neurotoxicity evaluation of N4-phthalimido phenyl (thio) semicarbazides. Eur J Pharm Sci 2003; 20: 341-346.
    • (2003) Eur J Pharm Sci , vol.20 , pp. 341-346
    • Yogeeswari, P.1    Sriram, D.2    Saraswat, V.3
  • 13
    • 56949083395 scopus 로고    scopus 로고
    • Newer GABA derivatives for the treatment of epilepsy including febrile seizures: A bioisosteric approach
    • Ragavendran JV, Sriram D, Kotapati S, et al. Newer GABA derivatives for the treatment of epilepsy including febrile seizures: a bioisosteric approach Eur. J Med Chem 2008;43:2650-2665.
    • (2008) Eur. J Med Chem , vol.43 , pp. 2650-2665
    • Ragavendran, J.V.1    Sriram, D.2    Kotapati, S.3
  • 14
    • 84873776176 scopus 로고
    • A method for evaluating both nonnarcotic and narcotic analgesics
    • Siegmund EA, Cadmus RA. A method for evaluating both nonnarcotic and narcotic analgesics. Proc Soc Exp Biol 1957; 95:729-731.
    • (1957) Proc Soc Exp Biol , vol.95 , pp. 729-731
    • Siegmund, E.A.1    Cadmus, R.A.2
  • 15
    • 0023895875 scopus 로고    scopus 로고
    • A peripheral mononeuropathy in rat that produces disorders of pain sensation like those seen in man
    • Bennett GJ, Xie YK. A peripheral mononeuropathy in rat that produces disorders of pain sensation like those seen in man. Pain 1998; 33:87-107.
    • (1998) Pain , vol.33 , pp. 87-107
    • Bennett, G.J.1    Xie, Y.K.2
  • 16
    • 0142216122 scopus 로고    scopus 로고
    • Antagonists of the j-opioid receptor enhances allodynia in rats and mice after sciatic nerve ligation
    • Obara I, Mika J, Schafer MKH, et al. Antagonists of the j-opioid receptor enhances allodynia in rats and mice after sciatic nerve ligation. Br J Pharmacol.2003;140: 538-545.
    • (2003) Br J Pharmacol , vol.140 , pp. 538-545
    • Obara, I.1    Mika, J.2    Schafer, M.K.H.3
  • 17
    • 0026727999 scopus 로고
    • An experimental model for peripheral neuropathy produced by segmental spinal nerve ligation in the rat
    • Kim S, Chung JM. An experimental model for peripheral neuropathy produced by segmental spinal nerve ligation in the rat. Pain 1992; 50:355-363.
    • (1992) Pain , vol.50 , pp. 355-363
    • Kim, S.1    Chung, J.M.2
  • 18
    • 0028558684 scopus 로고
    • Behavioral signs of ongoing pain and cold allodynia in a rat model of neuropathic pain
    • Choi Y, Yoon YW, Na HS, et al. Behavioral signs of ongoing pain and cold allodynia in a rat model of neuropathic pain. Pain 1994;59:369-376.
    • (1994) Pain , vol.59 , pp. 369-376
    • Choi, Y.1    Yoon, Y.W.2    Na, H.S.3
  • 19
    • 0032836174 scopus 로고    scopus 로고
    • Detection of static and dynamic components of mechanical allodynia in rat models of neuropathic pain: Are they signalled by distinct primary sensory neurones?
    • Field MJ, Bramwell S, Hughes J, et al. Detection of static and dynamic components of mechanical allodynia in rat models of neuropathic pain: Are they signalled by distinct primary sensory neurones? Pain 1999; 83:303-311.
    • (1999) Pain , vol.83 , pp. 303-311
    • Field, M.J.1    Bramwell, S.2    Hughes, J.3
  • 20
    • 0033030274 scopus 로고    scopus 로고
    • Gabapentin and pregabalin, but not morphine and amitriptyline, block both static and dynamic components of mechanical allodynia induced by streptozocin in the rat
    • Field MJ, McCleary S, Hughes J, et al. Gabapentin and pregabalin, but not morphine and amitriptyline, block both static and dynamic components of mechanical allodynia induced by streptozocin in the rat. Pain 1999; 80:391-398.
    • (1999) Pain , vol.80 , pp. 391-398
    • Field, M.J.1    McCleary, S.2    Hughes, J.3
  • 21
    • 0035073284 scopus 로고    scopus 로고
    • Intrathecally administered cholera toxin blocks allodynia and hyperalgesia in persistent pain models
    • Caudle RM, Mannes AJ, Benoliel R, et al. Intrathecally administered cholera toxin blocks allodynia and hyperalgesia in persistent pain models. J Pain 2001; 2:118-127.
    • (2001) J Pain , vol.2 , pp. 118-127
    • Caudle, R.M.1    Mannes, A.J.2    Benoliel, R.3
  • 22
    • 0033913719 scopus 로고    scopus 로고
    • Evaluation of selective NK1 receptor antagonist CI-1021 in animal models of inflammatory and neuropathic pain
    • Gonzalez MI, Field MJ, Hughes J, et al. Evaluation of selective NK1 receptor antagonist CI-1021 in animal models of inflammatory and neuropathic pain. J Pharmacol Exp Ther 2000; 294:444-450.
    • (2000) J Pharmacol Exp Ther , vol.294 , pp. 444-450
    • Gonzalez, M.I.1    Field, M.J.2    Hughes, J.3
  • 23
    • 0033600492 scopus 로고    scopus 로고
    • A single intrathecal injection of GABA permanently reverses neuropathic pain after nerve injury
    • Eaton MJ, Martinez MA, Karmally S. A single intrathecal injection of GABA permanently reverses neuropathic pain after nerve injury. Brain Res.1999; 835: 334-339.
    • (1999) Brain Res , vol.835 , pp. 334-339
    • Eaton, M.J.1    Martinez, M.A.2    Karmally, S.3
  • 24
    • 0030580562 scopus 로고    scopus 로고
    • Loss of GABA-immunoreactivity in the spinal dorsal horn of rats with peripheral nerve injury and promotion of recovery by adrenal medullary grafts
    • Ibuki T, Hama AT, Wang XT, et al. Loss of GABA-immunoreactivity in the spinal dorsal horn of rats with peripheral nerve injury and promotion of recovery by adrenal medullary grafts. Neuroscience 1997; 76: 845-858.
    • (1997) Neuroscience , vol.76 , pp. 845-858
    • Ibuki, T.1    Hama, A.T.2    Wang, X.T.3
  • 25
    • 0024602581 scopus 로고
    • Behavioral and autonomic correlates of the tactile evoked allodynia produced by spinal glycine inhibition: Effects of modulatory receptor systems and excitatory amino acid antagonists
    • Yaksh, TL. Behavioral and autonomic correlates of the tactile evoked allodynia produced by spinal glycine inhibition: effects of modulatory receptor systems and excitatory amino acid antagonists. Pain 1989;37: 111-123.
    • (1989) Pain , vol.37 , pp. 111-123
    • Yaksh, T.L.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.